RNA sequencing analysis of the developing chicken retina View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-12-20

AUTHORS

Christophe J. Langouet-Astrie, Annamarie L. Meinsen, Emily R. Grunwald, Stephen D. Turner, Raymond A. Enke

ABSTRACT

RNA sequencing transcriptome analysis using massively parallel next generation sequencing technology provides the capability to understand global changes in gene expression throughout a range of tissue samples. Development of the vertebrate retina requires complex temporal orchestration of transcriptional activation and repression. The chicken embryo (Gallus gallus) is a classic model system for studying developmental biology and retinogenesis. Existing retinal transcriptome projects have been critical to the vision research community for studying aspects of murine and human retinogenesis, however, there are currently no publicly available data sets describing the developing chicken retinal transcriptome. Here we used Illumina RNA sequencing (RNA-seq) analysis to characterize the mRNA transcriptome of the developing chicken retina in an effort to identify genes critical for retinal development in this important model organism. These data will be valuable to the vision research community for characterizing global changes in gene expression between ocular tissues and critical developmental time points during retinogenesis in the chicken retina. More... »

PAGES

160117

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/sdata.2016.117

DOI

http://dx.doi.org/10.1038/sdata.2016.117

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1017713388

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27996968


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