Characterization of hypoxia-associated molecular features to aid hypoxia-targeted therapy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-04

AUTHORS

Youqiong Ye, Qingsong Hu, Hu Chen, Ke Liang, Yuan Yuan, Yu Xiang, Hang Ruan, Zhao Zhang, Anren Song, Huiwen Zhang, Lingxiang Liu, Lixia Diao, Yanyan Lou, Bingying Zhou, Li Wang, Shengtao Zhou, Jianjun Gao, Eric Jonasch, Steven H. Lin, Yang Xia, Chunru Lin, Liuqing Yang, Gordon B. Mills, Han Liang, Leng Han

ABSTRACT

The conventional view holds that hypoxia confers drug resistance. In contrast, here the authors use a multilayer ‘omics data approach to characterize the molecular features associated with tumour hypoxia and identify molecular alterations that correlate with both drug-resistant and drug-sensitive responses to approved drugs.

PAGES

1

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    URI

    http://scigraph.springernature.com/pub.10.1038/s42255-019-0045-8

    DOI

    http://dx.doi.org/10.1038/s42255-019-0045-8

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1112847872


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