TGF-β2 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-02

AUTHORS

Hirokazu Takahashi, Christiano R. R. Alves, Kristin I. Stanford, Roeland J. W. Middelbeek, Pasquale Nigro, Rebecca E. Ryan, Ruidan Xue, Masaji Sakaguchi, Matthew D. Lynes, Kawai So, Joram D. Mul, Min-Young Lee, Estelle Balan, Hui Pan, Jonathan M. Dreyfuss, Michael F. Hirshman, Mohamad Azhar, Jarna C. Hannukainen, Pirjo Nuutila, Kari K. Kalliokoski, Søren Nielsen, Bente K. Pedersen, C. Ronald Kahn, Yu-Hua Tseng, Laurie J. Goodyear

ABSTRACT

Many beneficial effects of exercise are mediated by factors secreted from the exercising muscle, so-called myokines. Here, the authors identify what might be the first exercised-induced adipokine, TGF-β2, which is secreted from subcutaneous fat in response to exercise-induced increases in serum lactate levels and has beneficial metabolic effects in mice.

PAGES

291

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s42255-018-0030-7

DOI

http://dx.doi.org/10.1038/s42255-018-0030-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112060630


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