A magnetic antibody-conjugated nano-system for selective delivery of Ca(OH)2 and taxotere in ovarian cancer cells View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2022-09-21

AUTHORS

Reza Taheri-Ledari, Ehsan Zolfaghari, Simindokht Zarei-Shokat, Amir Kashtiaray, Ali Maleki

ABSTRACT

An efficient strategy for cancer therapy is presented, in which a tumor mass is initially pretreated with calcium hydroxide, then treated with Taxotere (TXT). In this regard, an advanced delivery system based on iron oxide nanoparticles has been designed. The surface of nanoparticles was functionalized with sortilin (SORT-1, a human IgG1 monoclonal antibody) that specifically encodes caov-4 ovarian cancerous cells. Plasmonic heating of the incorporated gold nanoparticles in polyvinyl alcohol (PVA) has been exploited to control the release process of TXT. The in vitro, ex vivo and in vivo experiments have exhibited high efficacy of a seven-day pretreatment by Ca(OH)2 plus 14 days treatment program by Ca(OH)2@Fe3O4/PVA/Au-SORT nano-therapeutics, where more penetration ratio resulted in tumor growth inhibition by ca. 78.3%. As a result, due to showing high values of the anti-tumor properties and biosafety, the presented pretreatment strategy is suggested for more effective treatment on the aged tumors. More... »

PAGES

995

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s42003-022-03966-w

DOI

http://dx.doi.org/10.1038/s42003-022-03966-w

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1151185687

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/36130999


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/03", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Chemical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0306", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Physical Chemistry (incl. Structural)", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antibodies, Monoclonal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Calcium Hydroxide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Docetaxel", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gold", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunoglobulin G", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Magnetic Phenomena", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Metal Nanoparticles", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ovarian Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polyvinyl Alcohol", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, 16846-13114, Tehran, Iran", 
          "id": "http://www.grid.ac/institutes/grid.411748.f", 
          "name": [
            "Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, 16846-13114, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Taheri-Ledari", 
        "givenName": "Reza", 
        "id": "sg:person.010362625417.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010362625417.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, 16846-13114, Tehran, Iran", 
          "id": "http://www.grid.ac/institutes/grid.411748.f", 
          "name": [
            "Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, 16846-13114, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zolfaghari", 
        "givenName": "Ehsan", 
        "id": "sg:person.016005657535.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016005657535.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, 16846-13114, Tehran, Iran", 
          "id": "http://www.grid.ac/institutes/grid.411748.f", 
          "name": [
            "Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, 16846-13114, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zarei-Shokat", 
        "givenName": "Simindokht", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, 16846-13114, Tehran, Iran", 
          "id": "http://www.grid.ac/institutes/grid.411748.f", 
          "name": [
            "Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, 16846-13114, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kashtiaray", 
        "givenName": "Amir", 
        "id": "sg:person.07733031723.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07733031723.90"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, 16846-13114, Tehran, Iran", 
          "id": "http://www.grid.ac/institutes/grid.411748.f", 
          "name": [
            "Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, 16846-13114, Tehran, Iran"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maleki", 
        "givenName": "Ali", 
        "id": "sg:person.0736660603.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736660603.36"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/s41467-020-20520-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1134522032", 
          "https://doi.org/10.1038/s41467-020-20520-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12668-020-00801-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1131948424", 
          "https://doi.org/10.1007/s12668-020-00801-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13238-016-0323-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034018913", 
          "https://doi.org/10.1007/s13238-016-0323-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10311-017-0618-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084024351", 
          "https://doi.org/10.1007/s10311-017-0618-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/labinvest.2017.116", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1092657338", 
          "https://doi.org/10.1038/labinvest.2017.116"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00018-018-2973-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1110226402", 
          "https://doi.org/10.1007/s00018-018-2973-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s40259-017-0254-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1092591128", 
          "https://doi.org/10.1007/s40259-017-0254-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nprot.2007.30", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016525230", 
          "https://doi.org/10.1038/nprot.2007.30"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00604-018-2908-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1105830370", 
          "https://doi.org/10.1007/s00604-018-2908-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12951-021-00982-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1140356558", 
          "https://doi.org/10.1186/s12951-021-00982-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/s41598-018-29736-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1105814186", 
          "https://doi.org/10.1038/s41598-018-29736-5"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2022-09-21", 
    "datePublishedReg": "2022-09-21", 
    "description": "An efficient strategy for cancer therapy is presented, in which a tumor mass is initially pretreated with calcium hydroxide, then treated with Taxotere (TXT). In this regard, an advanced delivery system based on iron oxide nanoparticles has been designed. The surface of nanoparticles was functionalized with sortilin (SORT-1, a human IgG1 monoclonal antibody) that specifically encodes caov-4 ovarian cancerous cells. Plasmonic heating of the incorporated gold nanoparticles in polyvinyl alcohol (PVA) has been exploited to control the release process of TXT. The in vitro, ex vivo and in vivo experiments have exhibited high efficacy of a seven-day pretreatment by Ca(OH)2 plus 14 days treatment program by Ca(OH)2@Fe3O4/PVA/Au-SORT nano-therapeutics, where more penetration ratio resulted in tumor growth inhibition by ca. 78.3%. As a result, due to showing high values of the anti-tumor properties and biosafety, the presented pretreatment strategy is suggested for more effective treatment on the aged tumors.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/s42003-022-03966-w", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1300829", 
        "issn": [
          "2399-3642"
        ], 
        "name": "Communications Biology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "5"
      }
    ], 
    "keywords": [
      "incorporated gold nanoparticles", 
      "iron oxide nanoparticles", 
      "surface of nanoparticles", 
      "advanced delivery systems", 
      "gold nanoparticles", 
      "oxide nanoparticles", 
      "polyvinyl alcohol", 
      "plasmonic heating", 
      "nanoparticles", 
      "delivery system", 
      "selective delivery", 
      "pretreatment strategies", 
      "efficient strategy", 
      "Seven-day pretreatment", 
      "cancer therapy", 
      "cancerous cells", 
      "ovarian cancerous cells", 
      "tumor growth inhibition", 
      "more effective treatments", 
      "ovarian cancer cells", 
      "day treatment program", 
      "anti-tumor properties", 
      "nano", 
      "Taxotere", 
      "tumor mass", 
      "effective treatment", 
      "ex vivo", 
      "treatment program", 
      "biosafety", 
      "release process", 
      "vivo experiments", 
      "cancer cells", 
      "high efficacy", 
      "growth inhibition", 
      "delivery", 
      "therapeutics", 
      "hydroxide", 
      "surface", 
      "cells", 
      "therapy", 
      "tumors", 
      "properties", 
      "calcium hydroxide", 
      "efficacy", 
      "sortilin", 
      "treatment", 
      "higher values", 
      "strategies", 
      "vivo", 
      "inhibition", 
      "pretreatment", 
      "alcohol", 
      "penetration ratio", 
      "Ca", 
      "system", 
      "ratio", 
      "heating", 
      "process", 
      "regard", 
      "program", 
      "mass", 
      "results", 
      "experiments", 
      "values"
    ], 
    "name": "A magnetic antibody-conjugated nano-system for selective delivery of Ca(OH)2 and taxotere in ovarian cancer cells", 
    "pagination": "995", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1151185687"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s42003-022-03966-w"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "36130999"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s42003-022-03966-w", 
      "https://app.dimensions.ai/details/publication/pub.1151185687"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-11-24T21:09", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221124/entities/gbq_results/article/article_931.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/s42003-022-03966-w"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s42003-022-03966-w'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s42003-022-03966-w'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s42003-022-03966-w'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s42003-022-03966-w'


 

This table displays all metadata directly associated to this object as RDF triples.

243 TRIPLES      21 PREDICATES      112 URIs      93 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s42003-022-03966-w schema:about N20b479b0230f4e3295946f1a5cc0701b
2 N6dc1f512f1864cd8811797d4ecc060e2
3 N93c583f9e07a4e46abf859dfcf7cf54f
4 Nb2a997293f4e44d3a3dd7cc83a07ff03
5 Nb4aeea054e2e4ca5b8bef6d548aa11d5
6 Nbc5f87185e7f441981c5b456237eae44
7 Nbf228c39b33e44cb8defe0486228487a
8 Nc15c3663906c42bb99a2618389906906
9 Nd78f53c68b5d4a6c88c22d9c0be26efb
10 Ne0e206d4ba344438abc3e6998ff4e05b
11 Nf430d5f3da29463085ba05f1ecc6dac5
12 Nfe668d0b8d824fc193698eda1e5644ac
13 anzsrc-for:03
14 anzsrc-for:0306
15 schema:author N953a1bfd27654d188010e42adfaf742d
16 schema:citation sg:pub.10.1007/s00018-018-2973-y
17 sg:pub.10.1007/s00604-018-2908-1
18 sg:pub.10.1007/s10311-017-0618-2
19 sg:pub.10.1007/s12668-020-00801-6
20 sg:pub.10.1007/s13238-016-0323-0
21 sg:pub.10.1007/s40259-017-0254-1
22 sg:pub.10.1038/labinvest.2017.116
23 sg:pub.10.1038/nprot.2007.30
24 sg:pub.10.1038/s41467-020-20520-6
25 sg:pub.10.1038/s41598-018-29736-5
26 sg:pub.10.1186/s12951-021-00982-6
27 schema:datePublished 2022-09-21
28 schema:datePublishedReg 2022-09-21
29 schema:description An efficient strategy for cancer therapy is presented, in which a tumor mass is initially pretreated with calcium hydroxide, then treated with Taxotere (TXT). In this regard, an advanced delivery system based on iron oxide nanoparticles has been designed. The surface of nanoparticles was functionalized with sortilin (SORT-1, a human IgG1 monoclonal antibody) that specifically encodes caov-4 ovarian cancerous cells. Plasmonic heating of the incorporated gold nanoparticles in polyvinyl alcohol (PVA) has been exploited to control the release process of TXT. The in vitro, ex vivo and in vivo experiments have exhibited high efficacy of a seven-day pretreatment by Ca(OH)2 plus 14 days treatment program by Ca(OH)2@Fe3O4/PVA/Au-SORT nano-therapeutics, where more penetration ratio resulted in tumor growth inhibition by ca. 78.3%. As a result, due to showing high values of the anti-tumor properties and biosafety, the presented pretreatment strategy is suggested for more effective treatment on the aged tumors.
30 schema:genre article
31 schema:isAccessibleForFree true
32 schema:isPartOf N2524870e59c140f9b59d60b9dd4fdcbf
33 N7a6161464e6642329bdd4ace66c2279f
34 sg:journal.1300829
35 schema:keywords Ca
36 Seven-day pretreatment
37 Taxotere
38 advanced delivery systems
39 alcohol
40 anti-tumor properties
41 biosafety
42 calcium hydroxide
43 cancer cells
44 cancer therapy
45 cancerous cells
46 cells
47 day treatment program
48 delivery
49 delivery system
50 effective treatment
51 efficacy
52 efficient strategy
53 ex vivo
54 experiments
55 gold nanoparticles
56 growth inhibition
57 heating
58 high efficacy
59 higher values
60 hydroxide
61 incorporated gold nanoparticles
62 inhibition
63 iron oxide nanoparticles
64 mass
65 more effective treatments
66 nano
67 nanoparticles
68 ovarian cancer cells
69 ovarian cancerous cells
70 oxide nanoparticles
71 penetration ratio
72 plasmonic heating
73 polyvinyl alcohol
74 pretreatment
75 pretreatment strategies
76 process
77 program
78 properties
79 ratio
80 regard
81 release process
82 results
83 selective delivery
84 sortilin
85 strategies
86 surface
87 surface of nanoparticles
88 system
89 therapeutics
90 therapy
91 treatment
92 treatment program
93 tumor growth inhibition
94 tumor mass
95 tumors
96 values
97 vivo
98 vivo experiments
99 schema:name A magnetic antibody-conjugated nano-system for selective delivery of Ca(OH)2 and taxotere in ovarian cancer cells
100 schema:pagination 995
101 schema:productId N1bcf9112a469440ebddf9109e01a821d
102 N57ddb03ae50d4f8cafe36771a5d9e1c7
103 N906f5017ad674716bd5a00182a99596c
104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1151185687
105 https://doi.org/10.1038/s42003-022-03966-w
106 schema:sdDatePublished 2022-11-24T21:09
107 schema:sdLicense https://scigraph.springernature.com/explorer/license/
108 schema:sdPublisher N64586b8c08934ab7a046bc5a48a79167
109 schema:url https://doi.org/10.1038/s42003-022-03966-w
110 sgo:license sg:explorer/license/
111 sgo:sdDataset articles
112 rdf:type schema:ScholarlyArticle
113 N1bcf9112a469440ebddf9109e01a821d schema:name doi
114 schema:value 10.1038/s42003-022-03966-w
115 rdf:type schema:PropertyValue
116 N20b479b0230f4e3295946f1a5cc0701b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Humans
118 rdf:type schema:DefinedTerm
119 N2524870e59c140f9b59d60b9dd4fdcbf schema:volumeNumber 5
120 rdf:type schema:PublicationVolume
121 N420a45caab7a4094993d2c4296ed0322 schema:affiliation grid-institutes:grid.411748.f
122 schema:familyName Zarei-Shokat
123 schema:givenName Simindokht
124 rdf:type schema:Person
125 N47737c70e03545a3ab57bafd8475badb rdf:first sg:person.016005657535.41
126 rdf:rest N70fa37c8ee4e49e4bf4696f77cdc0b5b
127 N4ebb0880323b4df6ae49c4c5b22c00d7 rdf:first sg:person.0736660603.36
128 rdf:rest rdf:nil
129 N57ddb03ae50d4f8cafe36771a5d9e1c7 schema:name dimensions_id
130 schema:value pub.1151185687
131 rdf:type schema:PropertyValue
132 N64586b8c08934ab7a046bc5a48a79167 schema:name Springer Nature - SN SciGraph project
133 rdf:type schema:Organization
134 N6dc1f512f1864cd8811797d4ecc060e2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Female
136 rdf:type schema:DefinedTerm
137 N70fa37c8ee4e49e4bf4696f77cdc0b5b rdf:first N420a45caab7a4094993d2c4296ed0322
138 rdf:rest Nb0e9da132418421cadac3baa16c9c475
139 N7a6161464e6642329bdd4ace66c2279f schema:issueNumber 1
140 rdf:type schema:PublicationIssue
141 N906f5017ad674716bd5a00182a99596c schema:name pubmed_id
142 schema:value 36130999
143 rdf:type schema:PropertyValue
144 N93c583f9e07a4e46abf859dfcf7cf54f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Magnetic Phenomena
146 rdf:type schema:DefinedTerm
147 N953a1bfd27654d188010e42adfaf742d rdf:first sg:person.010362625417.20
148 rdf:rest N47737c70e03545a3ab57bafd8475badb
149 Nb0e9da132418421cadac3baa16c9c475 rdf:first sg:person.07733031723.90
150 rdf:rest N4ebb0880323b4df6ae49c4c5b22c00d7
151 Nb2a997293f4e44d3a3dd7cc83a07ff03 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Polyvinyl Alcohol
153 rdf:type schema:DefinedTerm
154 Nb4aeea054e2e4ca5b8bef6d548aa11d5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Aged
156 rdf:type schema:DefinedTerm
157 Nbc5f87185e7f441981c5b456237eae44 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Immunoglobulin G
159 rdf:type schema:DefinedTerm
160 Nbf228c39b33e44cb8defe0486228487a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Metal Nanoparticles
162 rdf:type schema:DefinedTerm
163 Nc15c3663906c42bb99a2618389906906 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Gold
165 rdf:type schema:DefinedTerm
166 Nd78f53c68b5d4a6c88c22d9c0be26efb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Ovarian Neoplasms
168 rdf:type schema:DefinedTerm
169 Ne0e206d4ba344438abc3e6998ff4e05b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Antibodies, Monoclonal
171 rdf:type schema:DefinedTerm
172 Nf430d5f3da29463085ba05f1ecc6dac5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Calcium Hydroxide
174 rdf:type schema:DefinedTerm
175 Nfe668d0b8d824fc193698eda1e5644ac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Docetaxel
177 rdf:type schema:DefinedTerm
178 anzsrc-for:03 schema:inDefinedTermSet anzsrc-for:
179 schema:name Chemical Sciences
180 rdf:type schema:DefinedTerm
181 anzsrc-for:0306 schema:inDefinedTermSet anzsrc-for:
182 schema:name Physical Chemistry (incl. Structural)
183 rdf:type schema:DefinedTerm
184 sg:journal.1300829 schema:issn 2399-3642
185 schema:name Communications Biology
186 schema:publisher Springer Nature
187 rdf:type schema:Periodical
188 sg:person.010362625417.20 schema:affiliation grid-institutes:grid.411748.f
189 schema:familyName Taheri-Ledari
190 schema:givenName Reza
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010362625417.20
192 rdf:type schema:Person
193 sg:person.016005657535.41 schema:affiliation grid-institutes:grid.411748.f
194 schema:familyName Zolfaghari
195 schema:givenName Ehsan
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016005657535.41
197 rdf:type schema:Person
198 sg:person.0736660603.36 schema:affiliation grid-institutes:grid.411748.f
199 schema:familyName Maleki
200 schema:givenName Ali
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736660603.36
202 rdf:type schema:Person
203 sg:person.07733031723.90 schema:affiliation grid-institutes:grid.411748.f
204 schema:familyName Kashtiaray
205 schema:givenName Amir
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07733031723.90
207 rdf:type schema:Person
208 sg:pub.10.1007/s00018-018-2973-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1110226402
209 https://doi.org/10.1007/s00018-018-2973-y
210 rdf:type schema:CreativeWork
211 sg:pub.10.1007/s00604-018-2908-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1105830370
212 https://doi.org/10.1007/s00604-018-2908-1
213 rdf:type schema:CreativeWork
214 sg:pub.10.1007/s10311-017-0618-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084024351
215 https://doi.org/10.1007/s10311-017-0618-2
216 rdf:type schema:CreativeWork
217 sg:pub.10.1007/s12668-020-00801-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1131948424
218 https://doi.org/10.1007/s12668-020-00801-6
219 rdf:type schema:CreativeWork
220 sg:pub.10.1007/s13238-016-0323-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034018913
221 https://doi.org/10.1007/s13238-016-0323-0
222 rdf:type schema:CreativeWork
223 sg:pub.10.1007/s40259-017-0254-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092591128
224 https://doi.org/10.1007/s40259-017-0254-1
225 rdf:type schema:CreativeWork
226 sg:pub.10.1038/labinvest.2017.116 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092657338
227 https://doi.org/10.1038/labinvest.2017.116
228 rdf:type schema:CreativeWork
229 sg:pub.10.1038/nprot.2007.30 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016525230
230 https://doi.org/10.1038/nprot.2007.30
231 rdf:type schema:CreativeWork
232 sg:pub.10.1038/s41467-020-20520-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1134522032
233 https://doi.org/10.1038/s41467-020-20520-6
234 rdf:type schema:CreativeWork
235 sg:pub.10.1038/s41598-018-29736-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1105814186
236 https://doi.org/10.1038/s41598-018-29736-5
237 rdf:type schema:CreativeWork
238 sg:pub.10.1186/s12951-021-00982-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1140356558
239 https://doi.org/10.1186/s12951-021-00982-6
240 rdf:type schema:CreativeWork
241 grid-institutes:grid.411748.f schema:alternateName Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, 16846-13114, Tehran, Iran
242 schema:name Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, 16846-13114, Tehran, Iran
243 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...