Parental competition for the regulators of chromatin dynamics in mouse zygotes View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2022-07-14

AUTHORS

Masatoshi Ooga, Rei Inoue, Kousuke Kazama, Sayaka Wakayama, Satoshi Kamimura, Teruhiko Wakayama

ABSTRACT

The underlying mechanism for parental asymmetric chromatin dynamics is still unclear. To reveal this, we investigate chromatin dynamics in parthenogenetic, androgenic, and several types of male germ cells-fertilized zygotes. Here we illustrate that parental conflicting role mediates the regulation of chromatin dynamics. Sperm reduces chromatin dynamics in both parental pronuclei (PNs). During spermiogenesis, male germ cells acquire this reducing ability and its resistance. On the other hand, oocytes can increase chromatin dynamics. Notably, the oocytes-derived chromatin dynamics enhancing ability is dominant for the sperm-derived opposing one. This maternal enhancing ability is competed between parental pronuclei. Delayed fertilization timing is critical for this competition and compromises parental asymmetric chromatin dynamics and zygotic transcription. Together, parental competition for the maternal factor enhancing chromatin dynamics is a determinant to establish parental asymmetry, and paternal repressive effects have supporting roles to enhance asymmetry. More... »

PAGES

699

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s42003-022-03623-2

DOI

http://dx.doi.org/10.1038/s42003-022-03623-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1149469181

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/35835981


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1114", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Paediatrics and Reproductive Medicine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Nucleus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromatin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Histones", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Semen", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Zygote", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Animal Science and Biotechnology, School of Veterinary Medicine, Azabu University, 252-5201, Kanagawa, Japan", 
          "id": "http://www.grid.ac/institutes/grid.252643.4", 
          "name": [
            "Advanced Biotechnology Center, University of Yamanashi, 400-8510, Yamanashi, Japan", 
            "Faculty of Life and Environmental Sciences, University of Yamanashi, 400-8510, Yamanashi, Japan", 
            "Department of Animal Science and Biotechnology, School of Veterinary Medicine, Azabu University, 252-5201, Kanagawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ooga", 
        "givenName": "Masatoshi", 
        "id": "sg:person.01040220047.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01040220047.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Faculty of Life and Environmental Sciences, University of Yamanashi, 400-8510, Yamanashi, Japan", 
          "id": "http://www.grid.ac/institutes/grid.267500.6", 
          "name": [
            "Faculty of Life and Environmental Sciences, University of Yamanashi, 400-8510, Yamanashi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Inoue", 
        "givenName": "Rei", 
        "id": "sg:person.012623733215.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012623733215.90"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Faculty of Life and Environmental Sciences, University of Yamanashi, 400-8510, Yamanashi, Japan", 
          "id": "http://www.grid.ac/institutes/grid.267500.6", 
          "name": [
            "Faculty of Life and Environmental Sciences, University of Yamanashi, 400-8510, Yamanashi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kazama", 
        "givenName": "Kousuke", 
        "id": "sg:person.011420050407.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011420050407.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Advanced Biotechnology Center, University of Yamanashi, 400-8510, Yamanashi, Japan", 
          "id": "http://www.grid.ac/institutes/grid.267500.6", 
          "name": [
            "Advanced Biotechnology Center, University of Yamanashi, 400-8510, Yamanashi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wakayama", 
        "givenName": "Sayaka", 
        "id": "sg:person.01047105610.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01047105610.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Stem Cell Biology Team, Institute for Quantum Life Science, National Institutes for Quantum Science and Technology, 263-8555, Chiba, Japan", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Advanced Biotechnology Center, University of Yamanashi, 400-8510, Yamanashi, Japan", 
            "Stem Cell Biology Team, Institute for Quantum Life Science, National Institutes for Quantum Science and Technology, 263-8555, Chiba, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kamimura", 
        "givenName": "Satoshi", 
        "id": "sg:person.01165405737.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01165405737.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Advanced Biotechnology Center, University of Yamanashi, 400-8510, Yamanashi, Japan", 
          "id": "http://www.grid.ac/institutes/grid.267500.6", 
          "name": [
            "Advanced Biotechnology Center, University of Yamanashi, 400-8510, Yamanashi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wakayama", 
        "givenName": "Teruhiko", 
        "id": "sg:person.0744067475.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744067475.82"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/nsmb.1821", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049832803", 
          "https://doi.org/10.1038/nsmb.1821"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrm2439", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051604438", 
          "https://doi.org/10.1038/nrm2439"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-4939-8831-0_12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1107803546", 
          "https://doi.org/10.1007/978-1-4939-8831-0_12"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nsmb.2839", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039535564", 
          "https://doi.org/10.1038/nsmb.2839"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/s41594-020-00521-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1132441876", 
          "https://doi.org/10.1038/s41594-020-00521-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature08162", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041447218", 
          "https://doi.org/10.1038/nature08162"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2022-07-14", 
    "datePublishedReg": "2022-07-14", 
    "description": "The underlying mechanism for parental asymmetric chromatin dynamics is still unclear. To reveal this, we investigate chromatin dynamics in parthenogenetic, androgenic, and several types of male germ cells-fertilized zygotes. Here we illustrate that parental conflicting role mediates the regulation of chromatin dynamics. Sperm reduces chromatin dynamics in both parental pronuclei (PNs). During spermiogenesis, male germ cells acquire this reducing ability and its resistance. On the other hand, oocytes can increase chromatin dynamics. Notably, the oocytes-derived chromatin dynamics enhancing ability is dominant for the sperm-derived opposing one. This maternal enhancing ability is competed between parental pronuclei. Delayed fertilization timing is critical for this competition and compromises parental asymmetric chromatin dynamics and zygotic transcription. Together, parental competition for the maternal factor enhancing chromatin dynamics is a determinant to establish parental asymmetry, and paternal repressive effects have supporting roles to enhance asymmetry.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/s42003-022-03623-2", 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.8419373", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1300829", 
        "issn": [
          "2399-3642"
        ], 
        "name": "Communications Biology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "5"
      }
    ], 
    "keywords": [
      "chromatin dynamics", 
      "parental pronuclei", 
      "parental competition", 
      "male germ cells", 
      "zygotic transcription", 
      "parental asymmetry", 
      "mouse zygotes", 
      "repressive effect", 
      "germ cells", 
      "fertilization timing", 
      "zygotes", 
      "pronuclei", 
      "underlying mechanism", 
      "transcription", 
      "spermiogenesis", 
      "regulator", 
      "conflicting role", 
      "competition", 
      "regulation", 
      "oocytes", 
      "sperm", 
      "role", 
      "maternal factors", 
      "dynamics", 
      "cells", 
      "ability", 
      "mechanism", 
      "resistance", 
      "determinants", 
      "timing", 
      "factors", 
      "types", 
      "asymmetry", 
      "effect", 
      "hand"
    ], 
    "name": "Parental competition for the regulators of chromatin dynamics in mouse zygotes", 
    "pagination": "699", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1149469181"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s42003-022-03623-2"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "35835981"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s42003-022-03623-2", 
      "https://app.dimensions.ai/details/publication/pub.1149469181"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-09-02T16:08", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_948.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/s42003-022-03623-2"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s42003-022-03623-2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s42003-022-03623-2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s42003-022-03623-2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s42003-022-03623-2'


 

This table displays all metadata directly associated to this object as RDF triples.

199 TRIPLES      21 PREDICATES      74 URIs      60 LITERALS      15 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s42003-022-03623-2 schema:about N15945693e59c4de3b17485e48d1e05fa
2 N1f126ecbdc314d5fa817f4059258f0cc
3 N7428de642a4746acb32d1ec66f600858
4 N7906e682bc624e78b05ec4ac21555ce4
5 Naeeaad75992e47038b40c07fcf411a65
6 Nbd1e2f68710c40769cae6ddb53c68109
7 Nbd72c9ed4d9742879a28e9412ee32099
8 Nea5cd37916e1432fab16b423b2b30557
9 anzsrc-for:11
10 anzsrc-for:1114
11 schema:author Nf1f660fad3804be1aea96df9a7102c04
12 schema:citation sg:pub.10.1007/978-1-4939-8831-0_12
13 sg:pub.10.1038/nature08162
14 sg:pub.10.1038/nrm2439
15 sg:pub.10.1038/nsmb.1821
16 sg:pub.10.1038/nsmb.2839
17 sg:pub.10.1038/s41594-020-00521-1
18 schema:datePublished 2022-07-14
19 schema:datePublishedReg 2022-07-14
20 schema:description The underlying mechanism for parental asymmetric chromatin dynamics is still unclear. To reveal this, we investigate chromatin dynamics in parthenogenetic, androgenic, and several types of male germ cells-fertilized zygotes. Here we illustrate that parental conflicting role mediates the regulation of chromatin dynamics. Sperm reduces chromatin dynamics in both parental pronuclei (PNs). During spermiogenesis, male germ cells acquire this reducing ability and its resistance. On the other hand, oocytes can increase chromatin dynamics. Notably, the oocytes-derived chromatin dynamics enhancing ability is dominant for the sperm-derived opposing one. This maternal enhancing ability is competed between parental pronuclei. Delayed fertilization timing is critical for this competition and compromises parental asymmetric chromatin dynamics and zygotic transcription. Together, parental competition for the maternal factor enhancing chromatin dynamics is a determinant to establish parental asymmetry, and paternal repressive effects have supporting roles to enhance asymmetry.
21 schema:genre article
22 schema:isAccessibleForFree true
23 schema:isPartOf N7035df2ae3744f4cbd4ae2b1d82a6276
24 N938b4e0998b7489b97d29f1350f10c5a
25 sg:journal.1300829
26 schema:keywords ability
27 asymmetry
28 cells
29 chromatin dynamics
30 competition
31 conflicting role
32 determinants
33 dynamics
34 effect
35 factors
36 fertilization timing
37 germ cells
38 hand
39 male germ cells
40 maternal factors
41 mechanism
42 mouse zygotes
43 oocytes
44 parental asymmetry
45 parental competition
46 parental pronuclei
47 pronuclei
48 regulation
49 regulator
50 repressive effect
51 resistance
52 role
53 sperm
54 spermiogenesis
55 timing
56 transcription
57 types
58 underlying mechanism
59 zygotes
60 zygotic transcription
61 schema:name Parental competition for the regulators of chromatin dynamics in mouse zygotes
62 schema:pagination 699
63 schema:productId N023dec6972eb4f69abdad4282b395900
64 Nad6c861efd7a47839b80c038880c5adb
65 Nd40ed486c57a47e1a95574860237dd08
66 schema:sameAs https://app.dimensions.ai/details/publication/pub.1149469181
67 https://doi.org/10.1038/s42003-022-03623-2
68 schema:sdDatePublished 2022-09-02T16:08
69 schema:sdLicense https://scigraph.springernature.com/explorer/license/
70 schema:sdPublisher N885627f9ede947f6903da88a13602a14
71 schema:url https://doi.org/10.1038/s42003-022-03623-2
72 sgo:license sg:explorer/license/
73 sgo:sdDataset articles
74 rdf:type schema:ScholarlyArticle
75 N023dec6972eb4f69abdad4282b395900 schema:name doi
76 schema:value 10.1038/s42003-022-03623-2
77 rdf:type schema:PropertyValue
78 N15945693e59c4de3b17485e48d1e05fa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Male
80 rdf:type schema:DefinedTerm
81 N1f126ecbdc314d5fa817f4059258f0cc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name Zygote
83 rdf:type schema:DefinedTerm
84 N28f7f67752b340668b10236486e5969b rdf:first sg:person.011420050407.39
85 rdf:rest N9772e01adc574487a83bf4909bf0b552
86 N3185b254808b413585c9a30d6ba07425 rdf:first sg:person.012623733215.90
87 rdf:rest N28f7f67752b340668b10236486e5969b
88 N7035df2ae3744f4cbd4ae2b1d82a6276 schema:issueNumber 1
89 rdf:type schema:PublicationIssue
90 N7428de642a4746acb32d1ec66f600858 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Histones
92 rdf:type schema:DefinedTerm
93 N7906e682bc624e78b05ec4ac21555ce4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Semen
95 rdf:type schema:DefinedTerm
96 N885627f9ede947f6903da88a13602a14 schema:name Springer Nature - SN SciGraph project
97 rdf:type schema:Organization
98 N938b4e0998b7489b97d29f1350f10c5a schema:volumeNumber 5
99 rdf:type schema:PublicationVolume
100 N9772e01adc574487a83bf4909bf0b552 rdf:first sg:person.01047105610.48
101 rdf:rest N9ebb8e4263604c038fdde304dc2c9f76
102 N9ebb8e4263604c038fdde304dc2c9f76 rdf:first sg:person.01165405737.88
103 rdf:rest Nae20978bed33457a951ecd9063060857
104 Nad6c861efd7a47839b80c038880c5adb schema:name dimensions_id
105 schema:value pub.1149469181
106 rdf:type schema:PropertyValue
107 Nae20978bed33457a951ecd9063060857 rdf:first sg:person.0744067475.82
108 rdf:rest rdf:nil
109 Naeeaad75992e47038b40c07fcf411a65 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Chromatin
111 rdf:type schema:DefinedTerm
112 Nbd1e2f68710c40769cae6ddb53c68109 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Cell Nucleus
114 rdf:type schema:DefinedTerm
115 Nbd72c9ed4d9742879a28e9412ee32099 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Mice
117 rdf:type schema:DefinedTerm
118 Nd40ed486c57a47e1a95574860237dd08 schema:name pubmed_id
119 schema:value 35835981
120 rdf:type schema:PropertyValue
121 Nea5cd37916e1432fab16b423b2b30557 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Animals
123 rdf:type schema:DefinedTerm
124 Nf1f660fad3804be1aea96df9a7102c04 rdf:first sg:person.01040220047.27
125 rdf:rest N3185b254808b413585c9a30d6ba07425
126 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
127 schema:name Medical and Health Sciences
128 rdf:type schema:DefinedTerm
129 anzsrc-for:1114 schema:inDefinedTermSet anzsrc-for:
130 schema:name Paediatrics and Reproductive Medicine
131 rdf:type schema:DefinedTerm
132 sg:grant.8419373 http://pending.schema.org/fundedItem sg:pub.10.1038/s42003-022-03623-2
133 rdf:type schema:MonetaryGrant
134 sg:journal.1300829 schema:issn 2399-3642
135 schema:name Communications Biology
136 schema:publisher Springer Nature
137 rdf:type schema:Periodical
138 sg:person.01040220047.27 schema:affiliation grid-institutes:grid.252643.4
139 schema:familyName Ooga
140 schema:givenName Masatoshi
141 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01040220047.27
142 rdf:type schema:Person
143 sg:person.01047105610.48 schema:affiliation grid-institutes:grid.267500.6
144 schema:familyName Wakayama
145 schema:givenName Sayaka
146 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01047105610.48
147 rdf:type schema:Person
148 sg:person.011420050407.39 schema:affiliation grid-institutes:grid.267500.6
149 schema:familyName Kazama
150 schema:givenName Kousuke
151 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011420050407.39
152 rdf:type schema:Person
153 sg:person.01165405737.88 schema:affiliation grid-institutes:None
154 schema:familyName Kamimura
155 schema:givenName Satoshi
156 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01165405737.88
157 rdf:type schema:Person
158 sg:person.012623733215.90 schema:affiliation grid-institutes:grid.267500.6
159 schema:familyName Inoue
160 schema:givenName Rei
161 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012623733215.90
162 rdf:type schema:Person
163 sg:person.0744067475.82 schema:affiliation grid-institutes:grid.267500.6
164 schema:familyName Wakayama
165 schema:givenName Teruhiko
166 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744067475.82
167 rdf:type schema:Person
168 sg:pub.10.1007/978-1-4939-8831-0_12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1107803546
169 https://doi.org/10.1007/978-1-4939-8831-0_12
170 rdf:type schema:CreativeWork
171 sg:pub.10.1038/nature08162 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041447218
172 https://doi.org/10.1038/nature08162
173 rdf:type schema:CreativeWork
174 sg:pub.10.1038/nrm2439 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051604438
175 https://doi.org/10.1038/nrm2439
176 rdf:type schema:CreativeWork
177 sg:pub.10.1038/nsmb.1821 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049832803
178 https://doi.org/10.1038/nsmb.1821
179 rdf:type schema:CreativeWork
180 sg:pub.10.1038/nsmb.2839 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039535564
181 https://doi.org/10.1038/nsmb.2839
182 rdf:type schema:CreativeWork
183 sg:pub.10.1038/s41594-020-00521-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1132441876
184 https://doi.org/10.1038/s41594-020-00521-1
185 rdf:type schema:CreativeWork
186 grid-institutes:None schema:alternateName Stem Cell Biology Team, Institute for Quantum Life Science, National Institutes for Quantum Science and Technology, 263-8555, Chiba, Japan
187 schema:name Advanced Biotechnology Center, University of Yamanashi, 400-8510, Yamanashi, Japan
188 Stem Cell Biology Team, Institute for Quantum Life Science, National Institutes for Quantum Science and Technology, 263-8555, Chiba, Japan
189 rdf:type schema:Organization
190 grid-institutes:grid.252643.4 schema:alternateName Department of Animal Science and Biotechnology, School of Veterinary Medicine, Azabu University, 252-5201, Kanagawa, Japan
191 schema:name Advanced Biotechnology Center, University of Yamanashi, 400-8510, Yamanashi, Japan
192 Department of Animal Science and Biotechnology, School of Veterinary Medicine, Azabu University, 252-5201, Kanagawa, Japan
193 Faculty of Life and Environmental Sciences, University of Yamanashi, 400-8510, Yamanashi, Japan
194 rdf:type schema:Organization
195 grid-institutes:grid.267500.6 schema:alternateName Advanced Biotechnology Center, University of Yamanashi, 400-8510, Yamanashi, Japan
196 Faculty of Life and Environmental Sciences, University of Yamanashi, 400-8510, Yamanashi, Japan
197 schema:name Advanced Biotechnology Center, University of Yamanashi, 400-8510, Yamanashi, Japan
198 Faculty of Life and Environmental Sciences, University of Yamanashi, 400-8510, Yamanashi, Japan
199 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...