Peptidyl prolyl cis/trans isomerase activity on the cell surface correlates with extracellular matrix development View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-12

AUTHORS

Weilin Lin, Malte Bonin, Annett Boden, Robert Wieduwild, Priyanka Murawala, Martin Wermke, Helena Andrade, Martin Bornhäuser, Yixin Zhang

ABSTRACT

Interactions with the extracellular matrix (ECM) dictate cell fates. However, the complexity of dense ECM network and cell-surface molecules prevent the study of their dynamic interaction at the molecular level on living cells. Here, we focus on peptidyl prolyl cis/trans isomerases (PPIases) to dissect prolyl isomerization from other dynamic events. We reveal the contribution of PPIase on the mechanical properties of various ECM materials and on the dynamic cell-ECM interaction. To avoid complications associated with the existing spectroscopy-based methods such as light scattering, an assay was developed for detecting PPIase activity on living cell surface. This assay allows us to correlate PPIase activity with ECM development, and with the physiological and pathological states of the cells, including the functional properties of cancer cells and immune effector cells. More... »

PAGES

58

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s42003-019-0315-8

DOI

http://dx.doi.org/10.1038/s42003-019-0315-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112059108

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30775459


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "TU Dresden", 
          "id": "https://www.grid.ac/institutes/grid.4488.0", 
          "name": [
            "B CUBE Center for Molecular Bioengineering, Technische Universit\u00e4t Dresden, 01307, Dresden, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lin", 
        "givenName": "Weilin", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "German Cancer Research Center", 
          "id": "https://www.grid.ac/institutes/grid.7497.d", 
          "name": [
            "Medizinische Klinik und Poliklinik I, Universit\u00e4tsklinikum Carl Gustav Carus, 01307, Dresden, Germany", 
            "German Consortium for Translational Cancer Research (DKTK), partner site Dresden, Dresden, Germany", 
            "German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bonin", 
        "givenName": "Malte", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "TU Dresden", 
          "id": "https://www.grid.ac/institutes/grid.4488.0", 
          "name": [
            "B CUBE Center for Molecular Bioengineering, Technische Universit\u00e4t Dresden, 01307, Dresden, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Boden", 
        "givenName": "Annett", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "TU Dresden", 
          "id": "https://www.grid.ac/institutes/grid.4488.0", 
          "name": [
            "B CUBE Center for Molecular Bioengineering, Technische Universit\u00e4t Dresden, 01307, Dresden, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wieduwild", 
        "givenName": "Robert", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "TU Dresden", 
          "id": "https://www.grid.ac/institutes/grid.4488.0", 
          "name": [
            "B CUBE Center for Molecular Bioengineering, Technische Universit\u00e4t Dresden, 01307, Dresden, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Murawala", 
        "givenName": "Priyanka", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospital Carl Gustav Carus", 
          "id": "https://www.grid.ac/institutes/grid.412282.f", 
          "name": [
            "Medizinische Klinik und Poliklinik I, Universit\u00e4tsklinikum Carl Gustav Carus, 01307, Dresden, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wermke", 
        "givenName": "Martin", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "TU Dresden", 
          "id": "https://www.grid.ac/institutes/grid.4488.0", 
          "name": [
            "B CUBE Center for Molecular Bioengineering, Technische Universit\u00e4t Dresden, 01307, Dresden, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Andrade", 
        "givenName": "Helena", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospital Carl Gustav Carus", 
          "id": "https://www.grid.ac/institutes/grid.412282.f", 
          "name": [
            "Medizinische Klinik und Poliklinik I, Universit\u00e4tsklinikum Carl Gustav Carus, 01307, Dresden, Germany", 
            "German Consortium for Translational Cancer Research (DKTK), partner site Dresden, Dresden, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bornh\u00e4user", 
        "givenName": "Martin", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "TU Dresden", 
          "id": "https://www.grid.ac/institutes/grid.4488.0", 
          "name": [
            "B CUBE Center for Molecular Bioengineering, Technische Universit\u00e4t Dresden, 01307, Dresden, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhang", 
        "givenName": "Yixin", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/s0092-8674(00)80273-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001193780"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m409178200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001731980"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja043277y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007663803"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja043277y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007663803"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nchembio.2007.35", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013840110", 
          "https://doi.org/10.1038/nchembio.2007.35"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pbio.1000439", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014146594"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/346671a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014667477", 
          "https://doi.org/10.1038/346671a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1319448111", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017561925"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/asheducation-2002.1.73", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023178664"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m808964200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025710047"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmeth.3281", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026034813", 
          "https://doi.org/10.1038/nmeth.3281"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.052284899", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026953127"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nchem.120", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030482526", 
          "https://doi.org/10.1038/nchem.120"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nchem.120", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030482526", 
          "https://doi.org/10.1038/nchem.120"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0301-5629(94)00111-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034752155"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmeth.3257", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035393405", 
          "https://doi.org/10.1038/nmeth.3257"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.270.31.18323", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036332048"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/a803742f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036861168"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(91)90124-h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037884644"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0960-894x(95)00330-v", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038952892"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gad.1212704", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040020285"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/cddis.2013.410", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040943633", 
          "https://doi.org/10.1038/cddis.2013.410"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10254-003-0011-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041267791", 
          "https://doi.org/10.1007/s10254-003-0011-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc2107", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042182775", 
          "https://doi.org/10.1038/nrc2107"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc2107", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042182775", 
          "https://doi.org/10.1038/nrc2107"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbagen.2014.01.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046467939"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4838(84)90285-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050844364"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4838(84)90285-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050844364"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature01832", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052100299", 
          "https://doi.org/10.1038/nature01832"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature01832", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052100299", 
          "https://doi.org/10.1038/nature01832"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.87.23.9231", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052443578"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ac503960z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055019933"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079799870", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-12", 
    "datePublishedReg": "2019-12-01", 
    "description": "Interactions with the extracellular matrix (ECM) dictate cell fates. However, the complexity of dense ECM network and cell-surface molecules prevent the study of their dynamic interaction at the molecular level on living cells. Here, we focus on peptidyl prolyl cis/trans isomerases (PPIases) to dissect prolyl isomerization from other dynamic events. We reveal the contribution of PPIase on the mechanical properties of various ECM materials and on the dynamic cell-ECM interaction. To avoid complications associated with the existing spectroscopy-based methods such as light scattering, an assay was developed for detecting PPIase activity on living cell surface. This assay allows us to correlate PPIase activity with ECM development, and with the physiological and pathological states of the cells, including the functional properties of cancer cells and immune effector cells.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/s42003-019-0315-8", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1300829", 
        "issn": [
          "2399-3642"
        ], 
        "name": "Communications Biology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "2"
      }
    ], 
    "name": "Peptidyl prolyl cis/trans isomerase activity on the cell surface correlates with extracellular matrix development", 
    "pagination": "58", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "86b442f840b69d966c5869873419155d575ac95e78e0dc3dbcd4938130678a15"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30775459"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101719179"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s42003-019-0315-8"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1112059108"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s42003-019-0315-8", 
      "https://app.dimensions.ai/details/publication/pub.1112059108"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T09:08", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000338_0000000338/records_47957_00000002.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/s42003-019-0315-8"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s42003-019-0315-8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s42003-019-0315-8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s42003-019-0315-8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s42003-019-0315-8'


 

This table displays all metadata directly associated to this object as RDF triples.

216 TRIPLES      21 PREDICATES      57 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s42003-019-0315-8 schema:about anzsrc-for:06
2 anzsrc-for:0601
3 schema:author N4f0599a735174a8fbb91c768c7ea4d6f
4 schema:citation sg:pub.10.1007/s10254-003-0011-3
5 sg:pub.10.1038/346671a0
6 sg:pub.10.1038/cddis.2013.410
7 sg:pub.10.1038/nature01832
8 sg:pub.10.1038/nchem.120
9 sg:pub.10.1038/nchembio.2007.35
10 sg:pub.10.1038/nmeth.3257
11 sg:pub.10.1038/nmeth.3281
12 sg:pub.10.1038/nrc2107
13 https://app.dimensions.ai/details/publication/pub.1079799870
14 https://doi.org/10.1016/0092-8674(91)90124-h
15 https://doi.org/10.1016/0167-4838(84)90285-1
16 https://doi.org/10.1016/0960-894x(95)00330-v
17 https://doi.org/10.1016/j.bbagen.2014.01.010
18 https://doi.org/10.1016/s0092-8674(00)80273-1
19 https://doi.org/10.1016/s0301-5629(94)00111-1
20 https://doi.org/10.1021/ac503960z
21 https://doi.org/10.1021/ja043277y
22 https://doi.org/10.1039/a803742f
23 https://doi.org/10.1073/pnas.052284899
24 https://doi.org/10.1073/pnas.1319448111
25 https://doi.org/10.1073/pnas.87.23.9231
26 https://doi.org/10.1074/jbc.270.31.18323
27 https://doi.org/10.1074/jbc.m409178200
28 https://doi.org/10.1074/jbc.m808964200
29 https://doi.org/10.1101/gad.1212704
30 https://doi.org/10.1182/asheducation-2002.1.73
31 https://doi.org/10.1371/journal.pbio.1000439
32 schema:datePublished 2019-12
33 schema:datePublishedReg 2019-12-01
34 schema:description Interactions with the extracellular matrix (ECM) dictate cell fates. However, the complexity of dense ECM network and cell-surface molecules prevent the study of their dynamic interaction at the molecular level on living cells. Here, we focus on peptidyl prolyl <i>cis/trans</i> isomerases (PPIases) to dissect prolyl isomerization from other dynamic events. We reveal the contribution of PPIase on the mechanical properties of various ECM materials and on the dynamic cell-ECM interaction. To avoid complications associated with the existing spectroscopy-based methods such as light scattering, an assay was developed for detecting PPIase activity on living cell surface. This assay allows us to correlate PPIase activity with ECM development, and with the physiological and pathological states of the cells, including the functional properties of cancer cells and immune effector cells.
35 schema:genre research_article
36 schema:inLanguage en
37 schema:isAccessibleForFree false
38 schema:isPartOf N0061fcdd49b042eabad8365700ee701c
39 Nae81cb82aeb84bb3bf95f9a617c336a3
40 sg:journal.1300829
41 schema:name Peptidyl prolyl cis/trans isomerase activity on the cell surface correlates with extracellular matrix development
42 schema:pagination 58
43 schema:productId N005976a159b148888453507609256dfe
44 N8a0c06e8e40b483387f2eb8759e6c404
45 Naf5cfc09f1134561b3d03d940c1a840f
46 Nc7e685ce79db42c98ca0ff740ec7ce0b
47 Nfca50376747048f2a645fa162ce5c7c3
48 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112059108
49 https://doi.org/10.1038/s42003-019-0315-8
50 schema:sdDatePublished 2019-04-11T09:08
51 schema:sdLicense https://scigraph.springernature.com/explorer/license/
52 schema:sdPublisher Nd610e2270f0e47fc84a0c6caa14b0ed0
53 schema:url https://www.nature.com/articles/s42003-019-0315-8
54 sgo:license sg:explorer/license/
55 sgo:sdDataset articles
56 rdf:type schema:ScholarlyArticle
57 N005976a159b148888453507609256dfe schema:name dimensions_id
58 schema:value pub.1112059108
59 rdf:type schema:PropertyValue
60 N0061fcdd49b042eabad8365700ee701c schema:issueNumber 1
61 rdf:type schema:PublicationIssue
62 N00ccb5050cad4618861fbace485a70ff rdf:first N2356746f5d5e42eeba927880bc035655
63 rdf:rest N6c9646ec25144a6a9d69cb65abe5987e
64 N227d578bc2324459a22b5f4761d11fd5 rdf:first Nda721e4b9b474fabaff5911056146d72
65 rdf:rest N61b2a6016e76470aa63de997b51a5138
66 N2356746f5d5e42eeba927880bc035655 schema:affiliation https://www.grid.ac/institutes/grid.4488.0
67 schema:familyName Murawala
68 schema:givenName Priyanka
69 rdf:type schema:Person
70 N32b5589f73494a16949d9444db9b932a schema:affiliation https://www.grid.ac/institutes/grid.4488.0
71 schema:familyName Lin
72 schema:givenName Weilin
73 rdf:type schema:Person
74 N4f0599a735174a8fbb91c768c7ea4d6f rdf:first N32b5589f73494a16949d9444db9b932a
75 rdf:rest N8991fac754334ed6a96ecbae74ae58d1
76 N61b2a6016e76470aa63de997b51a5138 rdf:first N91c81c41b44f479a84cf7275fc6b9877
77 rdf:rest Nba9dfbda973a4396b59d712f4105bab4
78 N6c9646ec25144a6a9d69cb65abe5987e rdf:first Ncda5892819314d7c8a23ce69c23e526a
79 rdf:rest N227d578bc2324459a22b5f4761d11fd5
80 N6e9308c2ea20405e8d2707918931bf67 schema:affiliation https://www.grid.ac/institutes/grid.4488.0
81 schema:familyName Boden
82 schema:givenName Annett
83 rdf:type schema:Person
84 N70b6aa4e4d624271addf57c0f797c8de rdf:first N6e9308c2ea20405e8d2707918931bf67
85 rdf:rest Nc7d4fd9ea2a24b7e9c69c7bd31a2f4be
86 N8991fac754334ed6a96ecbae74ae58d1 rdf:first N9df58f09f619407d9dc796f30a05fe3c
87 rdf:rest N70b6aa4e4d624271addf57c0f797c8de
88 N8a0c06e8e40b483387f2eb8759e6c404 schema:name pubmed_id
89 schema:value 30775459
90 rdf:type schema:PropertyValue
91 N91c81c41b44f479a84cf7275fc6b9877 schema:affiliation https://www.grid.ac/institutes/grid.412282.f
92 schema:familyName Bornhäuser
93 schema:givenName Martin
94 rdf:type schema:Person
95 N9df58f09f619407d9dc796f30a05fe3c schema:affiliation https://www.grid.ac/institutes/grid.7497.d
96 schema:familyName Bonin
97 schema:givenName Malte
98 rdf:type schema:Person
99 Na9b2ba7819254ab9b63945c1d0a5c163 schema:affiliation https://www.grid.ac/institutes/grid.4488.0
100 schema:familyName Zhang
101 schema:givenName Yixin
102 rdf:type schema:Person
103 Nae81cb82aeb84bb3bf95f9a617c336a3 schema:volumeNumber 2
104 rdf:type schema:PublicationVolume
105 Naf5cfc09f1134561b3d03d940c1a840f schema:name nlm_unique_id
106 schema:value 101719179
107 rdf:type schema:PropertyValue
108 Nba9dfbda973a4396b59d712f4105bab4 rdf:first Na9b2ba7819254ab9b63945c1d0a5c163
109 rdf:rest rdf:nil
110 Nc7d4fd9ea2a24b7e9c69c7bd31a2f4be rdf:first Ne163bb6d722d4ec18fd2f37888eebe2d
111 rdf:rest N00ccb5050cad4618861fbace485a70ff
112 Nc7e685ce79db42c98ca0ff740ec7ce0b schema:name readcube_id
113 schema:value 86b442f840b69d966c5869873419155d575ac95e78e0dc3dbcd4938130678a15
114 rdf:type schema:PropertyValue
115 Ncda5892819314d7c8a23ce69c23e526a schema:affiliation https://www.grid.ac/institutes/grid.412282.f
116 schema:familyName Wermke
117 schema:givenName Martin
118 rdf:type schema:Person
119 Nd610e2270f0e47fc84a0c6caa14b0ed0 schema:name Springer Nature - SN SciGraph project
120 rdf:type schema:Organization
121 Nda721e4b9b474fabaff5911056146d72 schema:affiliation https://www.grid.ac/institutes/grid.4488.0
122 schema:familyName Andrade
123 schema:givenName Helena
124 rdf:type schema:Person
125 Ne163bb6d722d4ec18fd2f37888eebe2d schema:affiliation https://www.grid.ac/institutes/grid.4488.0
126 schema:familyName Wieduwild
127 schema:givenName Robert
128 rdf:type schema:Person
129 Nfca50376747048f2a645fa162ce5c7c3 schema:name doi
130 schema:value 10.1038/s42003-019-0315-8
131 rdf:type schema:PropertyValue
132 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
133 schema:name Biological Sciences
134 rdf:type schema:DefinedTerm
135 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
136 schema:name Biochemistry and Cell Biology
137 rdf:type schema:DefinedTerm
138 sg:journal.1300829 schema:issn 2399-3642
139 schema:name Communications Biology
140 rdf:type schema:Periodical
141 sg:pub.10.1007/s10254-003-0011-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041267791
142 https://doi.org/10.1007/s10254-003-0011-3
143 rdf:type schema:CreativeWork
144 sg:pub.10.1038/346671a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014667477
145 https://doi.org/10.1038/346671a0
146 rdf:type schema:CreativeWork
147 sg:pub.10.1038/cddis.2013.410 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040943633
148 https://doi.org/10.1038/cddis.2013.410
149 rdf:type schema:CreativeWork
150 sg:pub.10.1038/nature01832 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052100299
151 https://doi.org/10.1038/nature01832
152 rdf:type schema:CreativeWork
153 sg:pub.10.1038/nchem.120 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030482526
154 https://doi.org/10.1038/nchem.120
155 rdf:type schema:CreativeWork
156 sg:pub.10.1038/nchembio.2007.35 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013840110
157 https://doi.org/10.1038/nchembio.2007.35
158 rdf:type schema:CreativeWork
159 sg:pub.10.1038/nmeth.3257 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035393405
160 https://doi.org/10.1038/nmeth.3257
161 rdf:type schema:CreativeWork
162 sg:pub.10.1038/nmeth.3281 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026034813
163 https://doi.org/10.1038/nmeth.3281
164 rdf:type schema:CreativeWork
165 sg:pub.10.1038/nrc2107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042182775
166 https://doi.org/10.1038/nrc2107
167 rdf:type schema:CreativeWork
168 https://app.dimensions.ai/details/publication/pub.1079799870 schema:CreativeWork
169 https://doi.org/10.1016/0092-8674(91)90124-h schema:sameAs https://app.dimensions.ai/details/publication/pub.1037884644
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1016/0167-4838(84)90285-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050844364
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1016/0960-894x(95)00330-v schema:sameAs https://app.dimensions.ai/details/publication/pub.1038952892
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1016/j.bbagen.2014.01.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046467939
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1016/s0092-8674(00)80273-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001193780
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1016/s0301-5629(94)00111-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034752155
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1021/ac503960z schema:sameAs https://app.dimensions.ai/details/publication/pub.1055019933
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1021/ja043277y schema:sameAs https://app.dimensions.ai/details/publication/pub.1007663803
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1039/a803742f schema:sameAs https://app.dimensions.ai/details/publication/pub.1036861168
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1073/pnas.052284899 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026953127
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1073/pnas.1319448111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017561925
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1073/pnas.87.23.9231 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052443578
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1074/jbc.270.31.18323 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036332048
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1074/jbc.m409178200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001731980
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1074/jbc.m808964200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025710047
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1101/gad.1212704 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040020285
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1182/asheducation-2002.1.73 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023178664
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1371/journal.pbio.1000439 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014146594
204 rdf:type schema:CreativeWork
205 https://www.grid.ac/institutes/grid.412282.f schema:alternateName University Hospital Carl Gustav Carus
206 schema:name German Consortium for Translational Cancer Research (DKTK), partner site Dresden, Dresden, Germany
207 Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus, 01307, Dresden, Germany
208 rdf:type schema:Organization
209 https://www.grid.ac/institutes/grid.4488.0 schema:alternateName TU Dresden
210 schema:name B CUBE Center for Molecular Bioengineering, Technische Universität Dresden, 01307, Dresden, Germany
211 rdf:type schema:Organization
212 https://www.grid.ac/institutes/grid.7497.d schema:alternateName German Cancer Research Center
213 schema:name German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany
214 German Consortium for Translational Cancer Research (DKTK), partner site Dresden, Dresden, Germany
215 Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus, 01307, Dresden, Germany
216 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...