Light-induced structural changes in a full-length cyanobacterial phytochrome probed by time-resolved X-ray scattering View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-12

AUTHORS

Derren J. Heyes, Samantha J. O. Hardman, Martin N. Pedersen, Joyce Woodhouse, Eugenio De La Mora, Michael Wulff, Martin Weik, Marco Cammarata, Nigel S. Scrutton, Giorgio Schirò

ABSTRACT

Phytochromes are photoreceptor proteins that transmit a light signal from a photosensory region to an output domain. Photoconversion involves protein conformational changes whose nature is not fully understood. Here, we use time-resolved X-ray scattering and optical spectroscopy to study the kinetics of structural changes in a full-length cyanobacterial phytochrome and in a truncated form with no output domain. X-ray and spectroscopic signals on the µs/ms timescale are largely independent of the presence of the output domain. On longer time-scales, large differences between the full-length and truncated proteins indicate the timeframe during which the structural transition is transmitted from the photosensory region to the output domain and represent a large quaternary motion. The suggested independence of the photosensory-region dynamics on the µs/ms timescale defines a time window in which the photoreaction can be characterized (e.g. for optogenetic design) independently of the nature of the engineered output domain. More... »

PAGES

1

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s42003-018-0242-0

DOI

http://dx.doi.org/10.1038/s42003-018-0242-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1110929205

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30740537


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0299", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Other Physical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/02", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Physical Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Manchester", 
          "id": "https://www.grid.ac/institutes/grid.5379.8", 
          "name": [
            "Manchester Institute of Biotechnology, University of Manchester, 131 Princess St, M1 7DN, Manchester, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Heyes", 
        "givenName": "Derren J.", 
        "id": "sg:person.0625765417.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625765417.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Manchester", 
          "id": "https://www.grid.ac/institutes/grid.5379.8", 
          "name": [
            "Manchester Institute of Biotechnology, University of Manchester, 131 Princess St, M1 7DN, Manchester, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hardman", 
        "givenName": "Samantha J. O.", 
        "id": "sg:person.0674321035.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674321035.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "European Synchrotron Radiation Facility", 
          "id": "https://www.grid.ac/institutes/grid.5398.7", 
          "name": [
            "European Synchrotron Radiation Facility, 71 Avenue des Martyrs, 38044, Grenoble, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pedersen", 
        "givenName": "Martin N.", 
        "id": "sg:person.015542666637.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015542666637.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "French National Centre for Scientific Research", 
          "id": "https://www.grid.ac/institutes/grid.4444.0", 
          "name": [
            "Institut de Biologie Structurale, CNRS, Univ. Grenoble Alpes, CEA, 71 Avenue des Martyrs, 38044, Grenoble, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Woodhouse", 
        "givenName": "Joyce", 
        "id": "sg:person.01301317113.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01301317113.77"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "French National Centre for Scientific Research", 
          "id": "https://www.grid.ac/institutes/grid.4444.0", 
          "name": [
            "Institut de Biologie Structurale, CNRS, Univ. Grenoble Alpes, CEA, 71 Avenue des Martyrs, 38044, Grenoble, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "De La Mora", 
        "givenName": "Eugenio", 
        "id": "sg:person.0651301177.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0651301177.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "European Synchrotron Radiation Facility", 
          "id": "https://www.grid.ac/institutes/grid.5398.7", 
          "name": [
            "European Synchrotron Radiation Facility, 71 Avenue des Martyrs, 38044, Grenoble, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wulff", 
        "givenName": "Michael", 
        "id": "sg:person.01125534466.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125534466.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "French National Centre for Scientific Research", 
          "id": "https://www.grid.ac/institutes/grid.4444.0", 
          "name": [
            "Institut de Biologie Structurale, CNRS, Univ. Grenoble Alpes, CEA, 71 Avenue des Martyrs, 38044, Grenoble, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Weik", 
        "givenName": "Martin", 
        "id": "sg:person.01012747443.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012747443.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Univ. Rennes 1, CNRS, UBL, Institut de Physique de Rennes (IPR) - UMR 6251, 263 avenue du G\u00e9n\u00e9ral Leclerc, 35042, Rennes, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cammarata", 
        "givenName": "Marco", 
        "id": "sg:person.01125720070.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125720070.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Manchester", 
          "id": "https://www.grid.ac/institutes/grid.5379.8", 
          "name": [
            "Manchester Institute of Biotechnology, University of Manchester, 131 Princess St, M1 7DN, Manchester, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Scrutton", 
        "givenName": "Nigel S.", 
        "id": "sg:person.0615614611.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615614611.90"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "French National Centre for Scientific Research", 
          "id": "https://www.grid.ac/institutes/grid.4444.0", 
          "name": [
            "Institut de Biologie Structurale, CNRS, Univ. Grenoble Alpes, CEA, 71 Avenue des Martyrs, 38044, Grenoble, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schir\u00f2", 
        "givenName": "Giorgio", 
        "id": "sg:person.01263074266.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01263074266.61"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1074/jbc.m113.531053", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001994051"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.arplant.53.100301.135302", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003717496"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cphc.200900894", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009622908"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cphc.200900894", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009622908"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/sciadv.1600920", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011002208"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m115.650127", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011671797"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.str.2016.01.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012642749"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.str.2016.01.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012642749"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature13310", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024047828", 
          "https://doi.org/10.1038/nature13310"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0806477105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027707382"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1063/1.4961911", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036369424"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m608878200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044949723"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmeth.1255", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047288935", 
          "https://doi.org/10.1038/nmeth.1255"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0909049502006593", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048109317"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0052418", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049979400"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0076-6879(92)10010-b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052634618"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi002651d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055167703"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi002651d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055167703"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi971563z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055214372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi971563z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055214372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/sciadv.1602498", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084221016"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/acs.chemrev.6b00700", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084781252"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s1600576717007786", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1086274400"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cbic.201800016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101529778"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.ra118.003069", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103635394"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-12", 
    "datePublishedReg": "2019-12-01", 
    "description": "Phytochromes are photoreceptor proteins that transmit a light signal from a photosensory region to an output domain. Photoconversion involves protein conformational changes whose nature is not fully understood. Here, we use time-resolved X-ray scattering and optical spectroscopy to study the kinetics of structural changes in a full-length cyanobacterial phytochrome and in a truncated form with no output domain. X-ray and spectroscopic signals on the \u00b5s/ms timescale are largely independent of the presence of the output domain. On longer time-scales, large differences between the full-length and truncated proteins indicate the timeframe during which the structural transition is transmitted from the photosensory region to the output domain and represent a large quaternary motion. The suggested independence of the photosensory-region dynamics on the \u00b5s/ms timescale defines a time window in which the photoreaction can be characterized (e.g. for optogenetic design) independently of the nature of the engineered output domain.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/s42003-018-0242-0", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2778908", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1300829", 
        "issn": [
          "2399-3642"
        ], 
        "name": "Communications Biology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "2"
      }
    ], 
    "name": "Light-induced structural changes in a full-length cyanobacterial phytochrome probed by time-resolved X-ray scattering", 
    "pagination": "1", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "935a05563cbacf67577ec95cd82b9a1f0dd3ea7835ef5acd8d85f185fd4d2fd9"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30740537"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101719179"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s42003-018-0242-0"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1110929205"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s42003-018-0242-0", 
      "https://app.dimensions.ai/details/publication/pub.1110929205"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T09:03", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000333_0000000333/records_41726_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/s42003-018-0242-0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s42003-018-0242-0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s42003-018-0242-0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s42003-018-0242-0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s42003-018-0242-0'


 

This table displays all metadata directly associated to this object as RDF triples.

206 TRIPLES      21 PREDICATES      50 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s42003-018-0242-0 schema:about anzsrc-for:02
2 anzsrc-for:0299
3 schema:author N802f1a9a059e4b7788b70d3979570448
4 schema:citation sg:pub.10.1038/nature13310
5 sg:pub.10.1038/nmeth.1255
6 https://doi.org/10.1002/cbic.201800016
7 https://doi.org/10.1002/cphc.200900894
8 https://doi.org/10.1016/0076-6879(92)10010-b
9 https://doi.org/10.1016/j.str.2016.01.001
10 https://doi.org/10.1021/acs.chemrev.6b00700
11 https://doi.org/10.1021/bi002651d
12 https://doi.org/10.1021/bi971563z
13 https://doi.org/10.1063/1.4961911
14 https://doi.org/10.1073/pnas.0806477105
15 https://doi.org/10.1074/jbc.m113.531053
16 https://doi.org/10.1074/jbc.m115.650127
17 https://doi.org/10.1074/jbc.m608878200
18 https://doi.org/10.1074/jbc.ra118.003069
19 https://doi.org/10.1107/s0909049502006593
20 https://doi.org/10.1107/s1600576717007786
21 https://doi.org/10.1126/sciadv.1600920
22 https://doi.org/10.1126/sciadv.1602498
23 https://doi.org/10.1146/annurev.arplant.53.100301.135302
24 https://doi.org/10.1371/journal.pone.0052418
25 schema:datePublished 2019-12
26 schema:datePublishedReg 2019-12-01
27 schema:description Phytochromes are photoreceptor proteins that transmit a light signal from a photosensory region to an output domain. Photoconversion involves protein conformational changes whose nature is not fully understood. Here, we use time-resolved X-ray scattering and optical spectroscopy to study the kinetics of structural changes in a full-length cyanobacterial phytochrome and in a truncated form with no output domain. X-ray and spectroscopic signals on the µs/ms timescale are largely independent of the presence of the output domain. On longer time-scales, large differences between the full-length and truncated proteins indicate the timeframe during which the structural transition is transmitted from the photosensory region to the output domain and represent a large quaternary motion. The suggested independence of the photosensory-region dynamics on the µs/ms timescale defines a time window in which the photoreaction can be characterized (e.g. for optogenetic design) independently of the nature of the engineered output domain.
28 schema:genre research_article
29 schema:inLanguage en
30 schema:isAccessibleForFree false
31 schema:isPartOf N590ca9c1d8344b718509cd1e8e3a5c1b
32 Ne3be7c9847d240acaf08c6c91a508857
33 sg:journal.1300829
34 schema:name Light-induced structural changes in a full-length cyanobacterial phytochrome probed by time-resolved X-ray scattering
35 schema:pagination 1
36 schema:productId N13e11b04c02d4ff3847c5c64e432a69d
37 N2b86ad841122437fb44c2190778af239
38 N4b7941b554a64898992e2d4ceba4ef39
39 N6373f93e5ea04ec2986e30c3296f6e2d
40 N666c3bd0553a43468f5310546e92b8bf
41 schema:sameAs https://app.dimensions.ai/details/publication/pub.1110929205
42 https://doi.org/10.1038/s42003-018-0242-0
43 schema:sdDatePublished 2019-04-11T09:03
44 schema:sdLicense https://scigraph.springernature.com/explorer/license/
45 schema:sdPublisher Nb3e8fa2b871c42dd85bdde412f4a3a64
46 schema:url https://www.nature.com/articles/s42003-018-0242-0
47 sgo:license sg:explorer/license/
48 sgo:sdDataset articles
49 rdf:type schema:ScholarlyArticle
50 N0c174b7b08974f37ac13e2cda76ab4b4 schema:name Univ. Rennes 1, CNRS, UBL, Institut de Physique de Rennes (IPR) - UMR 6251, 263 avenue du Général Leclerc, 35042, Rennes, France
51 rdf:type schema:Organization
52 N0c87bfc01895435990dba0cf7c007742 rdf:first sg:person.01012747443.00
53 rdf:rest Nba4f633266ed402297ecece510ed585a
54 N13e11b04c02d4ff3847c5c64e432a69d schema:name nlm_unique_id
55 schema:value 101719179
56 rdf:type schema:PropertyValue
57 N171c0cfb974e426c86892b0d98e50f1e rdf:first sg:person.0651301177.21
58 rdf:rest Ne8698c31a0c6485496d3f17a3ac12616
59 N276acf9c7d4049f5b00c2e300d08778f rdf:first sg:person.0615614611.90
60 rdf:rest Ndd34f24c8ca24d97a7e50319ff613811
61 N2b86ad841122437fb44c2190778af239 schema:name pubmed_id
62 schema:value 30740537
63 rdf:type schema:PropertyValue
64 N4b7941b554a64898992e2d4ceba4ef39 schema:name doi
65 schema:value 10.1038/s42003-018-0242-0
66 rdf:type schema:PropertyValue
67 N590ca9c1d8344b718509cd1e8e3a5c1b schema:issueNumber 1
68 rdf:type schema:PublicationIssue
69 N6373f93e5ea04ec2986e30c3296f6e2d schema:name readcube_id
70 schema:value 935a05563cbacf67577ec95cd82b9a1f0dd3ea7835ef5acd8d85f185fd4d2fd9
71 rdf:type schema:PropertyValue
72 N666c3bd0553a43468f5310546e92b8bf schema:name dimensions_id
73 schema:value pub.1110929205
74 rdf:type schema:PropertyValue
75 N802f1a9a059e4b7788b70d3979570448 rdf:first sg:person.0625765417.72
76 rdf:rest N9df354fa2e7f4e86a9080370b2dc3a3c
77 N9df354fa2e7f4e86a9080370b2dc3a3c rdf:first sg:person.0674321035.10
78 rdf:rest Nee32006d09214bb7bd7c99ad964f0322
79 Nb3e8fa2b871c42dd85bdde412f4a3a64 schema:name Springer Nature - SN SciGraph project
80 rdf:type schema:Organization
81 Nba4f633266ed402297ecece510ed585a rdf:first sg:person.01125720070.53
82 rdf:rest N276acf9c7d4049f5b00c2e300d08778f
83 Nd18ec5271e764adca7187c343163044b rdf:first sg:person.01301317113.77
84 rdf:rest N171c0cfb974e426c86892b0d98e50f1e
85 Ndd34f24c8ca24d97a7e50319ff613811 rdf:first sg:person.01263074266.61
86 rdf:rest rdf:nil
87 Ne3be7c9847d240acaf08c6c91a508857 schema:volumeNumber 2
88 rdf:type schema:PublicationVolume
89 Ne8698c31a0c6485496d3f17a3ac12616 rdf:first sg:person.01125534466.63
90 rdf:rest N0c87bfc01895435990dba0cf7c007742
91 Nee32006d09214bb7bd7c99ad964f0322 rdf:first sg:person.015542666637.98
92 rdf:rest Nd18ec5271e764adca7187c343163044b
93 anzsrc-for:02 schema:inDefinedTermSet anzsrc-for:
94 schema:name Physical Sciences
95 rdf:type schema:DefinedTerm
96 anzsrc-for:0299 schema:inDefinedTermSet anzsrc-for:
97 schema:name Other Physical Sciences
98 rdf:type schema:DefinedTerm
99 sg:grant.2778908 http://pending.schema.org/fundedItem sg:pub.10.1038/s42003-018-0242-0
100 rdf:type schema:MonetaryGrant
101 sg:journal.1300829 schema:issn 2399-3642
102 schema:name Communications Biology
103 rdf:type schema:Periodical
104 sg:person.01012747443.00 schema:affiliation https://www.grid.ac/institutes/grid.4444.0
105 schema:familyName Weik
106 schema:givenName Martin
107 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012747443.00
108 rdf:type schema:Person
109 sg:person.01125534466.63 schema:affiliation https://www.grid.ac/institutes/grid.5398.7
110 schema:familyName Wulff
111 schema:givenName Michael
112 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125534466.63
113 rdf:type schema:Person
114 sg:person.01125720070.53 schema:affiliation N0c174b7b08974f37ac13e2cda76ab4b4
115 schema:familyName Cammarata
116 schema:givenName Marco
117 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125720070.53
118 rdf:type schema:Person
119 sg:person.01263074266.61 schema:affiliation https://www.grid.ac/institutes/grid.4444.0
120 schema:familyName Schirò
121 schema:givenName Giorgio
122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01263074266.61
123 rdf:type schema:Person
124 sg:person.01301317113.77 schema:affiliation https://www.grid.ac/institutes/grid.4444.0
125 schema:familyName Woodhouse
126 schema:givenName Joyce
127 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01301317113.77
128 rdf:type schema:Person
129 sg:person.015542666637.98 schema:affiliation https://www.grid.ac/institutes/grid.5398.7
130 schema:familyName Pedersen
131 schema:givenName Martin N.
132 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015542666637.98
133 rdf:type schema:Person
134 sg:person.0615614611.90 schema:affiliation https://www.grid.ac/institutes/grid.5379.8
135 schema:familyName Scrutton
136 schema:givenName Nigel S.
137 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615614611.90
138 rdf:type schema:Person
139 sg:person.0625765417.72 schema:affiliation https://www.grid.ac/institutes/grid.5379.8
140 schema:familyName Heyes
141 schema:givenName Derren J.
142 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625765417.72
143 rdf:type schema:Person
144 sg:person.0651301177.21 schema:affiliation https://www.grid.ac/institutes/grid.4444.0
145 schema:familyName De La Mora
146 schema:givenName Eugenio
147 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0651301177.21
148 rdf:type schema:Person
149 sg:person.0674321035.10 schema:affiliation https://www.grid.ac/institutes/grid.5379.8
150 schema:familyName Hardman
151 schema:givenName Samantha J. O.
152 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674321035.10
153 rdf:type schema:Person
154 sg:pub.10.1038/nature13310 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024047828
155 https://doi.org/10.1038/nature13310
156 rdf:type schema:CreativeWork
157 sg:pub.10.1038/nmeth.1255 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047288935
158 https://doi.org/10.1038/nmeth.1255
159 rdf:type schema:CreativeWork
160 https://doi.org/10.1002/cbic.201800016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101529778
161 rdf:type schema:CreativeWork
162 https://doi.org/10.1002/cphc.200900894 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009622908
163 rdf:type schema:CreativeWork
164 https://doi.org/10.1016/0076-6879(92)10010-b schema:sameAs https://app.dimensions.ai/details/publication/pub.1052634618
165 rdf:type schema:CreativeWork
166 https://doi.org/10.1016/j.str.2016.01.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012642749
167 rdf:type schema:CreativeWork
168 https://doi.org/10.1021/acs.chemrev.6b00700 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084781252
169 rdf:type schema:CreativeWork
170 https://doi.org/10.1021/bi002651d schema:sameAs https://app.dimensions.ai/details/publication/pub.1055167703
171 rdf:type schema:CreativeWork
172 https://doi.org/10.1021/bi971563z schema:sameAs https://app.dimensions.ai/details/publication/pub.1055214372
173 rdf:type schema:CreativeWork
174 https://doi.org/10.1063/1.4961911 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036369424
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1073/pnas.0806477105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027707382
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1074/jbc.m113.531053 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001994051
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1074/jbc.m115.650127 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011671797
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1074/jbc.m608878200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044949723
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1074/jbc.ra118.003069 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103635394
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1107/s0909049502006593 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048109317
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1107/s1600576717007786 schema:sameAs https://app.dimensions.ai/details/publication/pub.1086274400
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1126/sciadv.1600920 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011002208
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1126/sciadv.1602498 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084221016
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1146/annurev.arplant.53.100301.135302 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003717496
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1371/journal.pone.0052418 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049979400
197 rdf:type schema:CreativeWork
198 https://www.grid.ac/institutes/grid.4444.0 schema:alternateName French National Centre for Scientific Research
199 schema:name Institut de Biologie Structurale, CNRS, Univ. Grenoble Alpes, CEA, 71 Avenue des Martyrs, 38044, Grenoble, France
200 rdf:type schema:Organization
201 https://www.grid.ac/institutes/grid.5379.8 schema:alternateName University of Manchester
202 schema:name Manchester Institute of Biotechnology, University of Manchester, 131 Princess St, M1 7DN, Manchester, UK
203 rdf:type schema:Organization
204 https://www.grid.ac/institutes/grid.5398.7 schema:alternateName European Synchrotron Radiation Facility
205 schema:name European Synchrotron Radiation Facility, 71 Avenue des Martyrs, 38044, Grenoble, France
206 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...