Impact of exercise capacity on the long-term incidence of atrial arrhythmias in heart failure View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2021-09-21

AUTHORS

Tetsuri Sakai, Atsuhiko Yagishita, Masahiro Morise, Susumu Sakama, Takeshi Ijichi, Kengo Ayabe, Mari Amino, Yuji Ikari, Koichiro Yoshioka

ABSTRACT

We sought to demonstrate the impact of improved peak exercise oxygen consumption (V̇O2) during maximal exercise testing after cardiac rehabilitation (CR) on the incidence of arrhythmias in patients with heart failure (HF). The present study comprised of 220 patients with HF, and peak V̇O2 was examined at 2 and 5 months after CR. Of the 220 patients, 110 (50%) had a low peak V̇O2 of < 14 mL/min/kg at 2 months. The peak V̇O2 improved in 86 of these 110 (78%) patients at 5 months after CR. During a median follow-up of 6 years, the patients with improvement in peak V̇O2, compared to those without peak V̇O2 improvement, had a lower rate of mortality (4% vs. 29%, log-rank, P < 0.001) and HF hospitalization (6 vs. 17%, log-rank, P = 0.044) and a lower incidence of new-onset atrial arrhythmias (9 vs. 27%, log-rank, P = 0.013), with no difference in the incidence of ventricular arrhythmias between groups (1 vs. 4%, log-rank, P = 0.309). The majority of deaths in the patients without an improved peak V̇O2 were because of cardiovascular events (73%), particularly progressive HF (55%). Early detection and management of atrial arrhythmias may improve outcomes in patients without peak V̇O2 improvement after CR. More... »

PAGES

18705

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41598-021-98172-9

DOI

http://dx.doi.org/10.1038/s41598-021-98172-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1141267178

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/34548557


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