Ontology type: schema:ScholarlyArticle Open Access: True
2021-06-03
AUTHORSMasatsune Ishikawa, Shigeki Yamada, Masakazu Miyajima, Hiroaki Kazui, Etsuro Mori
ABSTRACTIdiopathic normal pressure hydrocephalus (iNPH) is a surgically treatable syndrome commonly observed in older adults. However, it is unclear whether clinical improvements after surgery can effectively reduce the long-term care burden (LTCB). In this study, we determined whether shunt surgery was effective in decreasing LTCB. We also investigated the degree of variability in patients and hospitals, using data from the iNPH multicenter study. This study involved 69 participants who underwent lumboperitoneal shunt surgery with follow-up for 12 months. A generalized linear mixed model was applied to analyze the fixed and random effects simultaneously. Regarding LTCB, the disability grades improved significantly. Although the dementia grades also improved, it was not statistically significant. The differences in the LTCB grades in most patients were within the range of the 95% confidence intervals, while in the case of hospitals, some were often out of the range. Further studies are needed to improve dementia in patients with iNPH. The incorporation of random variables, such as hospitals, is important for the analysis of data from multicenter studies. More... »
PAGES11732
http://scigraph.springernature.com/pub.10.1038/s41598-021-90911-2
DOIhttp://dx.doi.org/10.1038/s41598-021-90911-2
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1138572399
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/34083550
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Aged, 80 and over",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cost of Illness",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Female",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Hydrocephalus, Normal Pressure",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Long-Term Care",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Male",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Middle Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Postoperative Period",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Prognosis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Public Health Surveillance",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Randomized Controlled Trials as Topic",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Severity of Illness Index",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Treatment Outcome",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Normal Pressure Hydrocephalus Centre, Otowa Hospital, Kyoto, Kyoto, Japan",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Rakuwa Villa Ilios, Kyoto, Kyoto, Japan",
"Normal Pressure Hydrocephalus Centre, Otowa Hospital, Kyoto, Kyoto, Japan"
],
"type": "Organization"
},
"familyName": "Ishikawa",
"givenName": "Masatsune",
"id": "sg:person.013554460012.28",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013554460012.28"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Neurosurgery, Shiga University of Medical Science, Otsu, Shiga, Japan",
"id": "http://www.grid.ac/institutes/grid.410827.8",
"name": [
"Normal Pressure Hydrocephalus Centre, Otowa Hospital, Kyoto, Kyoto, Japan",
"Department of Neurosurgery, Shiga University of Medical Science, Otsu, Shiga, Japan"
],
"type": "Organization"
},
"familyName": "Yamada",
"givenName": "Shigeki",
"id": "sg:person.01076300413.35",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01076300413.35"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Neurosurgery, Juntendo Tokyo Koto Geriatric Medical Center, Kotoku, Tokyo, Japan",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Department of Neurosurgery, Juntendo Tokyo Koto Geriatric Medical Center, Kotoku, Tokyo, Japan"
],
"type": "Organization"
},
"familyName": "Miyajima",
"givenName": "Masakazu",
"id": "sg:person.01202611574.46",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202611574.46"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Neuropsychiatry, Kochi Medical School, Kochi University, Nankoku, Kochi, Japan",
"id": "http://www.grid.ac/institutes/grid.415887.7",
"name": [
"Department of Neuropsychiatry, Kochi Medical School, Kochi University, Nankoku, Kochi, Japan"
],
"type": "Organization"
},
"familyName": "Kazui",
"givenName": "Hiroaki",
"id": "sg:person.01207327153.52",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207327153.52"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Behavioral Neurology and Neuropsychiatry, Osaka University United Graduate School of Child Development, Toyonaka, Osaka, Japan",
"id": "http://www.grid.ac/institutes/grid.136593.b",
"name": [
"Department of Behavioral Neurology and Neuropsychiatry, Osaka University United Graduate School of Child Development, Toyonaka, Osaka, Japan"
],
"type": "Organization"
},
"familyName": "Mori",
"givenName": "Etsuro",
"id": "sg:person.0661603724.75",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0661603724.75"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1186/1472-6963-13-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038217934",
"https://doi.org/10.1186/1472-6963-13-2"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/1743-8454-7-18",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1078293303",
"https://doi.org/10.1186/1743-8454-7-18"
],
"type": "CreativeWork"
}
],
"datePublished": "2021-06-03",
"datePublishedReg": "2021-06-03",
"description": "Idiopathic normal pressure hydrocephalus (iNPH) is a surgically treatable syndrome commonly observed in older adults. However, it is unclear whether clinical improvements after surgery can effectively reduce the long-term care burden (LTCB). In this study, we determined whether shunt surgery was effective in decreasing LTCB. We also investigated the degree of variability in patients and hospitals, using data from the iNPH multicenter study. This study involved 69 participants who underwent lumboperitoneal shunt surgery with follow-up for 12\u00a0months. A generalized linear mixed model was applied to analyze the fixed and random effects simultaneously. Regarding LTCB, the disability grades improved significantly. Although the dementia grades also improved, it was not statistically significant. The differences in the LTCB grades in most patients were within the range of the 95% confidence intervals, while in the case of hospitals, some were often out of the range. Further studies are needed to improve dementia in patients with iNPH. The incorporation of random variables, such as hospitals, is important for the analysis of data from multicenter studies.",
"genre": "article",
"id": "sg:pub.10.1038/s41598-021-90911-2",
"inLanguage": "en",
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1045337",
"issn": [
"2045-2322"
],
"name": "Scientific Reports",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "11"
}
],
"keywords": [
"idiopathic normal pressure hydrocephalus",
"long-term care burden",
"normal pressure hydrocephalus",
"shunt surgery",
"pressure hydrocephalus",
"multicenter study",
"care burden",
"lumboperitoneal shunt surgery",
"treatable syndrome",
"clinical improvement",
"most patients",
"surgical treatment",
"disability grade",
"patients",
"surgery",
"older adults",
"hospital",
"confidence intervals",
"linear mixed models",
"hydrocephalus",
"Further studies",
"case of hospitals",
"burden",
"mixed models",
"grade",
"generalized linear mixed model",
"random effects",
"syndrome",
"supplementary study",
"dementia",
"study",
"months",
"analysis of data",
"adults",
"treatment",
"degree of variability",
"participants",
"improvement",
"interval",
"data",
"differences",
"cases",
"effect",
"variables",
"degree",
"variability",
"analysis",
"incorporation",
"range",
"model",
"random variables"
],
"name": "Improvement in the long-term care burden after surgical treatment of patients with idiopathic normal pressure hydrocephalus: a supplementary study",
"pagination": "11732",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1138572399"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/s41598-021-90911-2"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"34083550"
]
}
],
"sameAs": [
"https://doi.org/10.1038/s41598-021-90911-2",
"https://app.dimensions.ai/details/publication/pub.1138572399"
],
"sdDataset": "articles",
"sdDatePublished": "2022-05-10T10:33",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220509/entities/gbq_results/article/article_918.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1038/s41598-021-90911-2"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41598-021-90911-2'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41598-021-90911-2'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41598-021-90911-2'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41598-021-90911-2'
This table displays all metadata directly associated to this object as RDF triples.
221 TRIPLES
22 PREDICATES
94 URIs
84 LITERALS
22 BLANK NODES