Use of direct oral anticoagulants does not significantly increase delayed bleeding after endoscopic submucosal dissection for early gastric neoplasms View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2021-04-30

AUTHORS

Jinju Choi, Soo-Jeong Cho, Sang-Hoon Na, Ayoung Lee, Jue Lie Kim, Hyunsoo Chung, Sang Gyun Kim

ABSTRACT

Direct oral anticoagulants (DOACs) are widely prescribed for the prevention of stroke in elderly patients with atrial fibrillation and approved indication for DOAC has been expanded. We aimed to evaluate the risk of delayed bleeding in patients who had taken DOAC and underwent endoscopic submucosal dissection (ESD) for gastric neoplasms. We included consecutive patients who underwent ESD between January 2016 and July 2019 in Seoul National University Hospital. Patients were divided into four groups (no med; no medication, DOAC, WFR; warfarin, anti-PLT; anti-platelet agent) according to the medications they had been taken before the procedure. We defined delayed bleeding as obvious post-procedural gastrointestinal bleeding sign including hematemesis or melena combined with hemoglobin drop ≥ 2 g/dL. Among 1634 patients enrolled in this study, 23 (1.4%) patients had taken DOAC and they usually stopped the medication for 2 days before the ESD and resumed within 1 or 2 days. We compared rates of delayed bleeding between groups. Delayed bleeding rates of the groups of no med, DOAC, WFR, and anti-PLT were 2.1% (32/1499) 8.7% (2/23), 14.3% (2/14), 11.2% (11/98), respectively (P < 0.001). However, there was no difference of delayed bleeding rate between no med and DOAC group after propensity score matching (no med vs DOAC, 1.7% vs 10.0%, P = 0.160). Taking DOAC was not associated statistically with post-ESD bleeding when adjusted by age, sex, comorbidities and characteristics of target lesion (Adjusted Odds Ratio: 2.4, 95% Confidence intervals: 0.41–13.73, P = 0.335). Crude rate of bleeding in DOAC users seemed to be higher than no medication group after performing ESD with 2 days of medication cessation. When adjusted by age, sex, and comorbidity, however, this difference seems to be small, which suggests that gastric post-ESD bleeding may be influenced by patients’ underlying condition in addition to medication use. More... »

PAGES

9399

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41598-021-88656-z

DOI

http://dx.doi.org/10.1038/s41598-021-88656-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1137611813

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/33931685


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adenocarcinoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adenoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Endoscopic Mucosal Resection", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Factor Xa Inhibitors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Postoperative Hemorrhage", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Stomach Neoplasms", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, 101, Daehak-ro Jongno-gu, 03080, Seoul, Korea", 
          "id": "http://www.grid.ac/institutes/grid.412484.f", 
          "name": [
            "Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, 101, Daehak-ro Jongno-gu, 03080, Seoul, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Choi", 
        "givenName": "Jinju", 
        "id": "sg:person.014723510217.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014723510217.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, 101, Daehak-ro Jongno-gu, 03080, Seoul, Korea", 
          "id": "http://www.grid.ac/institutes/grid.412484.f", 
          "name": [
            "Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, 101, Daehak-ro Jongno-gu, 03080, Seoul, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cho", 
        "givenName": "Soo-Jeong", 
        "id": "sg:person.0641563624.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0641563624.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea", 
          "id": "http://www.grid.ac/institutes/grid.412484.f", 
          "name": [
            "Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Na", 
        "givenName": "Sang-Hoon", 
        "id": "sg:person.01107124247.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01107124247.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, 101, Daehak-ro Jongno-gu, 03080, Seoul, Korea", 
          "id": "http://www.grid.ac/institutes/grid.412484.f", 
          "name": [
            "Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, 101, Daehak-ro Jongno-gu, 03080, Seoul, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lee", 
        "givenName": "Ayoung", 
        "id": "sg:person.015231121233.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015231121233.73"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, 101, Daehak-ro Jongno-gu, 03080, Seoul, Korea", 
          "id": "http://www.grid.ac/institutes/grid.412484.f", 
          "name": [
            "Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, 101, Daehak-ro Jongno-gu, 03080, Seoul, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Jue Lie", 
        "id": "sg:person.016671262361.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016671262361.60"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, 101, Daehak-ro Jongno-gu, 03080, Seoul, Korea", 
          "id": "http://www.grid.ac/institutes/grid.412484.f", 
          "name": [
            "Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, 101, Daehak-ro Jongno-gu, 03080, Seoul, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chung", 
        "givenName": "Hyunsoo", 
        "id": "sg:person.01051267505.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01051267505.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, 101, Daehak-ro Jongno-gu, 03080, Seoul, Korea", 
          "id": "http://www.grid.ac/institutes/grid.412484.f", 
          "name": [
            "Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, 101, Daehak-ro Jongno-gu, 03080, Seoul, Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Sang Gyun", 
        "id": "sg:person.016035435043.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016035435043.00"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s10120-015-0588-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020316695", 
          "https://doi.org/10.1007/s10120-015-0588-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-230x-14-172", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048414039", 
          "https://doi.org/10.1186/1471-230x-14-172"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10120-020-01105-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1129477785", 
          "https://doi.org/10.1007/s10120-020-01105-0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2021-04-30", 
    "datePublishedReg": "2021-04-30", 
    "description": "Direct oral anticoagulants (DOACs) are widely prescribed for the prevention of stroke in elderly patients with atrial fibrillation and approved indication for DOAC has been expanded. We aimed to evaluate the risk of delayed bleeding in patients who had taken DOAC and underwent endoscopic submucosal dissection (ESD) for gastric neoplasms. We included consecutive patients who underwent ESD between January 2016 and July 2019 in Seoul National University Hospital. Patients were divided into four groups (no med; no medication, DOAC, WFR; warfarin, anti-PLT; anti-platelet agent) according to the medications they had been taken before the procedure. We defined delayed bleeding as obvious post-procedural gastrointestinal bleeding sign including hematemesis or melena combined with hemoglobin drop\u2009\u2265\u20092\u00a0g/dL. Among 1634 patients enrolled in this study, 23 (1.4%) patients had taken DOAC and they usually stopped the medication for 2\u00a0days before the ESD and resumed within 1 or 2\u00a0days. We compared rates of delayed bleeding between groups. Delayed bleeding rates of the groups of no med, DOAC, WFR, and anti-PLT were 2.1% (32/1499) 8.7% (2/23), 14.3% (2/14), 11.2% (11/98), respectively (P\u2009<\u20090.001). However, there was no difference of delayed bleeding rate between no med and DOAC group after propensity score matching (no med vs DOAC, 1.7% vs 10.0%, P\u2009=\u20090.160). Taking DOAC was not associated statistically with post-ESD bleeding when adjusted by age, sex, comorbidities and characteristics of target lesion (Adjusted Odds Ratio: 2.4, 95% Confidence intervals: 0.41\u201313.73, P\u2009=\u20090.335). Crude rate of bleeding in DOAC users seemed to be higher than no medication group after performing ESD with 2\u00a0days of medication cessation. When adjusted by age, sex, and comorbidity, however, this difference seems to be small, which suggests that gastric post-ESD bleeding may be influenced by patients\u2019 underlying condition in addition to medication use.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/s41598-021-88656-z", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1045337", 
        "issn": [
          "2045-2322"
        ], 
        "name": "Scientific Reports", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "11"
      }
    ], 
    "keywords": [
      "direct oral anticoagulants", 
      "endoscopic submucosal dissection", 
      "post-ESD bleeding", 
      "oral anticoagulants", 
      "submucosal dissection", 
      "gastric neoplasms", 
      "Seoul National University Hospital", 
      "prevention of stroke", 
      "early gastric neoplasms", 
      "National University Hospital", 
      "DOAC group", 
      "DOAC users", 
      "hemoglobin drop", 
      "medication cessation", 
      "elderly patients", 
      "medication group", 
      "consecutive patients", 
      "medication use", 
      "atrial fibrillation", 
      "bleeding signs", 
      "University Hospital", 
      "target lesions", 
      "crude rate", 
      "patients", 
      "propensity score", 
      "bleeding", 
      "comorbidities", 
      "medications", 
      "anticoagulants", 
      "neoplasms", 
      "dissection", 
      "age", 
      "days", 
      "sex", 
      "group", 
      "MED", 
      "hematemesis", 
      "melena", 
      "fibrillation", 
      "hospital", 
      "lesions", 
      "stroke", 
      "prevention", 
      "cessation", 
      "rate", 
      "differences", 
      "scores", 
      "risk", 
      "PLT", 
      "signs", 
      "WFR", 
      "indications", 
      "use", 
      "study", 
      "procedure", 
      "addition", 
      "characteristics", 
      "conditions", 
      "drop", 
      "users"
    ], 
    "name": "Use of direct oral anticoagulants does not significantly increase delayed bleeding after endoscopic submucosal dissection for early gastric neoplasms", 
    "pagination": "9399", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1137611813"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s41598-021-88656-z"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "33931685"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s41598-021-88656-z", 
      "https://app.dimensions.ai/details/publication/pub.1137611813"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-10-01T06:49", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_890.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/s41598-021-88656-z"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41598-021-88656-z'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41598-021-88656-z'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41598-021-88656-z'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41598-021-88656-z'


 

This table displays all metadata directly associated to this object as RDF triples.

224 TRIPLES      21 PREDICATES      100 URIs      89 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s41598-021-88656-z schema:about N0ac1e8da77fe4f5f8c132479656ae637
2 N4887b5fdfb2547afb0eafd29ad06b8e6
3 N4a62b990659d41c098742f8a229256a1
4 N6bc1cbadb2d9487783b2d8a10ba17bb3
5 N6c7bb67c5118445ab78803d7112983c1
6 N7a6eee6912794040a4a4822a858ee6ac
7 N8f36a7787d6c45dd999ac636def11eb2
8 Nbfa7c54c3820433291b2995714577424
9 Nc78bec3eb36b48d0be47c14523b9b624
10 Nd953d4fce8d54dad9bfb65ddea1db144
11 Ne1758e7756c64a9090f36e1c9c90fde3
12 Nfae06d50f65d420ca54fe514fb1f16c2
13 anzsrc-for:11
14 anzsrc-for:1117
15 schema:author Nca795054fcd04c62b331f3a18f657090
16 schema:citation sg:pub.10.1007/s10120-015-0588-7
17 sg:pub.10.1007/s10120-020-01105-0
18 sg:pub.10.1186/1471-230x-14-172
19 schema:datePublished 2021-04-30
20 schema:datePublishedReg 2021-04-30
21 schema:description Direct oral anticoagulants (DOACs) are widely prescribed for the prevention of stroke in elderly patients with atrial fibrillation and approved indication for DOAC has been expanded. We aimed to evaluate the risk of delayed bleeding in patients who had taken DOAC and underwent endoscopic submucosal dissection (ESD) for gastric neoplasms. We included consecutive patients who underwent ESD between January 2016 and July 2019 in Seoul National University Hospital. Patients were divided into four groups (no med; no medication, DOAC, WFR; warfarin, anti-PLT; anti-platelet agent) according to the medications they had been taken before the procedure. We defined delayed bleeding as obvious post-procedural gastrointestinal bleeding sign including hematemesis or melena combined with hemoglobin drop ≥ 2 g/dL. Among 1634 patients enrolled in this study, 23 (1.4%) patients had taken DOAC and they usually stopped the medication for 2 days before the ESD and resumed within 1 or 2 days. We compared rates of delayed bleeding between groups. Delayed bleeding rates of the groups of no med, DOAC, WFR, and anti-PLT were 2.1% (32/1499) 8.7% (2/23), 14.3% (2/14), 11.2% (11/98), respectively (P < 0.001). However, there was no difference of delayed bleeding rate between no med and DOAC group after propensity score matching (no med vs DOAC, 1.7% vs 10.0%, P = 0.160). Taking DOAC was not associated statistically with post-ESD bleeding when adjusted by age, sex, comorbidities and characteristics of target lesion (Adjusted Odds Ratio: 2.4, 95% Confidence intervals: 0.41–13.73, P = 0.335). Crude rate of bleeding in DOAC users seemed to be higher than no medication group after performing ESD with 2 days of medication cessation. When adjusted by age, sex, and comorbidity, however, this difference seems to be small, which suggests that gastric post-ESD bleeding may be influenced by patients’ underlying condition in addition to medication use.
22 schema:genre article
23 schema:isAccessibleForFree true
24 schema:isPartOf N5e2bc94e84fe421793dc35ae8c588095
25 Nb135966ff4f548e1a723457b4114af3e
26 sg:journal.1045337
27 schema:keywords DOAC group
28 DOAC users
29 MED
30 National University Hospital
31 PLT
32 Seoul National University Hospital
33 University Hospital
34 WFR
35 addition
36 age
37 anticoagulants
38 atrial fibrillation
39 bleeding
40 bleeding signs
41 cessation
42 characteristics
43 comorbidities
44 conditions
45 consecutive patients
46 crude rate
47 days
48 differences
49 direct oral anticoagulants
50 dissection
51 drop
52 early gastric neoplasms
53 elderly patients
54 endoscopic submucosal dissection
55 fibrillation
56 gastric neoplasms
57 group
58 hematemesis
59 hemoglobin drop
60 hospital
61 indications
62 lesions
63 medication cessation
64 medication group
65 medication use
66 medications
67 melena
68 neoplasms
69 oral anticoagulants
70 patients
71 post-ESD bleeding
72 prevention
73 prevention of stroke
74 procedure
75 propensity score
76 rate
77 risk
78 scores
79 sex
80 signs
81 stroke
82 study
83 submucosal dissection
84 target lesions
85 use
86 users
87 schema:name Use of direct oral anticoagulants does not significantly increase delayed bleeding after endoscopic submucosal dissection for early gastric neoplasms
88 schema:pagination 9399
89 schema:productId N49bb65637075423390e45e8107f7f1e7
90 Na532b6fb8acb422bb113de187b6c1942
91 Nda323c222b414899b7f88147143f03d6
92 schema:sameAs https://app.dimensions.ai/details/publication/pub.1137611813
93 https://doi.org/10.1038/s41598-021-88656-z
94 schema:sdDatePublished 2022-10-01T06:49
95 schema:sdLicense https://scigraph.springernature.com/explorer/license/
96 schema:sdPublisher N66f4137d06454bd19cd5f58f071a09e2
97 schema:url https://doi.org/10.1038/s41598-021-88656-z
98 sgo:license sg:explorer/license/
99 sgo:sdDataset articles
100 rdf:type schema:ScholarlyArticle
101 N08ad9755efe4411c991c61a72cc6ccc8 rdf:first sg:person.015231121233.73
102 rdf:rest N150352209bb6498c93cb488315eb776e
103 N0ac1e8da77fe4f5f8c132479656ae637 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Retrospective Studies
105 rdf:type schema:DefinedTerm
106 N150352209bb6498c93cb488315eb776e rdf:first sg:person.016671262361.60
107 rdf:rest Nefb87c1365004fd6a75a803f8702c90f
108 N4887b5fdfb2547afb0eafd29ad06b8e6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Middle Aged
110 rdf:type schema:DefinedTerm
111 N49bb65637075423390e45e8107f7f1e7 schema:name dimensions_id
112 schema:value pub.1137611813
113 rdf:type schema:PropertyValue
114 N4a62b990659d41c098742f8a229256a1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Endoscopic Mucosal Resection
116 rdf:type schema:DefinedTerm
117 N5e2bc94e84fe421793dc35ae8c588095 schema:volumeNumber 11
118 rdf:type schema:PublicationVolume
119 N66f4137d06454bd19cd5f58f071a09e2 schema:name Springer Nature - SN SciGraph project
120 rdf:type schema:Organization
121 N6bc1cbadb2d9487783b2d8a10ba17bb3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Postoperative Hemorrhage
123 rdf:type schema:DefinedTerm
124 N6c7bb67c5118445ab78803d7112983c1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Male
126 rdf:type schema:DefinedTerm
127 N7a6eee6912794040a4a4822a858ee6ac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Factor Xa Inhibitors
129 rdf:type schema:DefinedTerm
130 N8f36a7787d6c45dd999ac636def11eb2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Stomach Neoplasms
132 rdf:type schema:DefinedTerm
133 N9c0a59f5a7334680b2cac5d5083cfe24 rdf:first sg:person.016035435043.00
134 rdf:rest rdf:nil
135 Na532b6fb8acb422bb113de187b6c1942 schema:name pubmed_id
136 schema:value 33931685
137 rdf:type schema:PropertyValue
138 Nb135966ff4f548e1a723457b4114af3e schema:issueNumber 1
139 rdf:type schema:PublicationIssue
140 Nbfa7c54c3820433291b2995714577424 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Aged
142 rdf:type schema:DefinedTerm
143 Nc78bec3eb36b48d0be47c14523b9b624 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Humans
145 rdf:type schema:DefinedTerm
146 Nca795054fcd04c62b331f3a18f657090 rdf:first sg:person.014723510217.58
147 rdf:rest Ne3ff40b5dd0c4ee88e21694104c86280
148 Nd953d4fce8d54dad9bfb65ddea1db144 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Female
150 rdf:type schema:DefinedTerm
151 Nda323c222b414899b7f88147143f03d6 schema:name doi
152 schema:value 10.1038/s41598-021-88656-z
153 rdf:type schema:PropertyValue
154 Ndd0f5fe2212b4b7e963ca5796303ae6b rdf:first sg:person.01107124247.95
155 rdf:rest N08ad9755efe4411c991c61a72cc6ccc8
156 Ne1758e7756c64a9090f36e1c9c90fde3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Adenocarcinoma
158 rdf:type schema:DefinedTerm
159 Ne3ff40b5dd0c4ee88e21694104c86280 rdf:first sg:person.0641563624.14
160 rdf:rest Ndd0f5fe2212b4b7e963ca5796303ae6b
161 Nefb87c1365004fd6a75a803f8702c90f rdf:first sg:person.01051267505.19
162 rdf:rest N9c0a59f5a7334680b2cac5d5083cfe24
163 Nfae06d50f65d420ca54fe514fb1f16c2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Adenoma
165 rdf:type schema:DefinedTerm
166 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
167 schema:name Medical and Health Sciences
168 rdf:type schema:DefinedTerm
169 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
170 schema:name Public Health and Health Services
171 rdf:type schema:DefinedTerm
172 sg:journal.1045337 schema:issn 2045-2322
173 schema:name Scientific Reports
174 schema:publisher Springer Nature
175 rdf:type schema:Periodical
176 sg:person.01051267505.19 schema:affiliation grid-institutes:grid.412484.f
177 schema:familyName Chung
178 schema:givenName Hyunsoo
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01051267505.19
180 rdf:type schema:Person
181 sg:person.01107124247.95 schema:affiliation grid-institutes:grid.412484.f
182 schema:familyName Na
183 schema:givenName Sang-Hoon
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01107124247.95
185 rdf:type schema:Person
186 sg:person.014723510217.58 schema:affiliation grid-institutes:grid.412484.f
187 schema:familyName Choi
188 schema:givenName Jinju
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014723510217.58
190 rdf:type schema:Person
191 sg:person.015231121233.73 schema:affiliation grid-institutes:grid.412484.f
192 schema:familyName Lee
193 schema:givenName Ayoung
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015231121233.73
195 rdf:type schema:Person
196 sg:person.016035435043.00 schema:affiliation grid-institutes:grid.412484.f
197 schema:familyName Kim
198 schema:givenName Sang Gyun
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016035435043.00
200 rdf:type schema:Person
201 sg:person.016671262361.60 schema:affiliation grid-institutes:grid.412484.f
202 schema:familyName Kim
203 schema:givenName Jue Lie
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016671262361.60
205 rdf:type schema:Person
206 sg:person.0641563624.14 schema:affiliation grid-institutes:grid.412484.f
207 schema:familyName Cho
208 schema:givenName Soo-Jeong
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0641563624.14
210 rdf:type schema:Person
211 sg:pub.10.1007/s10120-015-0588-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020316695
212 https://doi.org/10.1007/s10120-015-0588-7
213 rdf:type schema:CreativeWork
214 sg:pub.10.1007/s10120-020-01105-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1129477785
215 https://doi.org/10.1007/s10120-020-01105-0
216 rdf:type schema:CreativeWork
217 sg:pub.10.1186/1471-230x-14-172 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048414039
218 https://doi.org/10.1186/1471-230x-14-172
219 rdf:type schema:CreativeWork
220 grid-institutes:grid.412484.f schema:alternateName Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
221 Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, 101, Daehak-ro Jongno-gu, 03080, Seoul, Korea
222 schema:name Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
223 Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, 101, Daehak-ro Jongno-gu, 03080, Seoul, Korea
224 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...