Controlling the transverse proton relaxivity of magnetic graphene oxide. View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Bibek Thapa, Daysi Diaz-Diestra, Dayra Badillo-Diaz, Rohit Kumar Sharma, Kiran Dasari, Shalini Kumari, Mikel B Holcomb, Juan Beltran-Huarac, Brad R Weiner, Gerardo Morell

ABSTRACT

The engineering of materials with controlled magnetic properties by means other than a magnetic field is of great interest in nanotechnology. In this study, we report engineered magnetic graphene oxide (MGO) in the nanocomposite form of iron oxide nanoparticles (IO)-graphene oxide (GO) with tunable core magnetism and magnetic resonance transverse relaxivity (r2). These tunable properties are obtained by varying the IO content on GO. The MGO series exhibits r2 values analogous to those observed in conventional single core and cluster forms of IO in different size regimes-motional averaging regime (MAR), static dephasing regime (SDR), and echo-limiting regime (ELR) or slow motion regime (SMR). The maximum r2 of 162 ± 5.703 mM-1s-1 is attained for MGO with 28 weight percent (wt%) content of IO on GO and hydrodynamic diameter of 414 nm, which is associated with the SDR. These findings demonstrate the clear potential of magnetic graphene oxide for magnetic resonance imaging (MRI) applications. More... »

PAGES

5633

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/s41598-019-42093-1

    DOI

    http://dx.doi.org/10.1038/s41598-019-42093-1

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1113185014

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30948768


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