Ontology type: schema:ScholarlyArticle Open Access: True
2019-12
AUTHORSMaxim Verboven, Anne Cuypers, Dorien Deluyker, Ivo Lambrichts, Bert O Eijnde, Dominique Hansen, Virginie Bito
ABSTRACTExercise training is a low cost and safe approach for reducing the risk of cardiovascular disease development. Currently, moderate-intensity training (MIT) is the most preferred exercise type. However, high-intensity interval training (HIIT) is gaining interest especially among athletes and healthy individuals. In this study, we examined cardiac remodeling resulting from MIT and HIIT in healthy rats. Healthy male Sprague-Dawley rats were randomly assigned to MIT or HIIT for 13 weeks. Animals kept sedentary (SED) were used as control. Cardiac function was evaluated with echocardiography and hemodynamic measurements. Heart tissue was stained for capillary density and fibrosis. After 13 weeks of training, only HIIT induced beneficial cardiac hypertrophy. Overall global cardiac parameters (such as ejection fraction, cardiac output and volumes) were improved similarly between both training modalities. At tissue level, collagen content was significantly and similarly reduced in both exercise groups. Finally, only HIIT increased significantly capillary density. Our data indicate that even if very different in design, HIIT and MIT appear to be equally effective in improving cardiac function in healthy rats. Furthermore, HIIT provides additional benefits through improved capillary density and should therefore be considered as a preferred training modality for athletes and for patients. More... »
PAGES5612
http://scigraph.springernature.com/pub.10.1038/s41598-019-42023-1
DOIhttp://dx.doi.org/10.1038/s41598-019-42023-1
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curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41598-019-42023-1'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41598-019-42023-1'
This table displays all metadata directly associated to this object as RDF triples.
273 TRIPLES
21 PREDICATES
83 URIs
20 LITERALS
8 BLANK NODES