Active propagation of dendritic electrical signals in C. elegans View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Tomomi Shindou, Mayumi Ochi-Shindou, Takashi Murayama, Ei-ichiro Saita, Yuto Momohara, Jeffery R. Wickens, Ichiro N. Maruyama

ABSTRACT

Active propagation of electrical signals in C. elegans neurons requires ion channels capable of regenerating membrane potentials. Here we report regenerative depolarization of a major gustatory sensory neuron, ASEL. Whole-cell patch-clamp recordings in vivo showed supralinear depolarization of ASEL upon current injection. Furthermore, stimulation of animal's nose with NaCl evoked all-or-none membrane depolarization in ASEL. Mutant analysis showed that EGL-19, the α1 subunit of L-type voltage-gated Ca2+ channels, is essential for regenerative depolarization of ASEL. ASEL-specific knock-down of EGL-19 by RNAi demonstrated that EGL-19 functions in C. elegans chemotaxis along an NaCl gradient. These results demonstrate that a natural substance induces regenerative all-or-none electrical signals in dendrites, and that these signals are essential for activation of sensory neurons for chemotaxis. As in other vertebrate and invertebrate nervous systems, active information processing in dendrites occurs in C. elegans, and is necessary for adaptive behavior. More... »

PAGES

3430

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41598-019-40158-9

DOI

http://dx.doi.org/10.1038/s41598-019-40158-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112544068

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30837592


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Okinawa Institute of Science and Technology", 
          "id": "https://www.grid.ac/institutes/grid.250464.1", 
          "name": [
            "Neurobiology Research Unit, Okinawa Institute of Science and Technology Graduate University, 904-0495, Okinawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shindou", 
        "givenName": "Tomomi", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Okinawa Institute of Science and Technology", 
          "id": "https://www.grid.ac/institutes/grid.250464.1", 
          "name": [
            "Neurobiology Research Unit, Okinawa Institute of Science and Technology Graduate University, 904-0495, Okinawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ochi-Shindou", 
        "givenName": "Mayumi", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Okinawa Institute of Science and Technology", 
          "id": "https://www.grid.ac/institutes/grid.250464.1", 
          "name": [
            "Information Processing Biology Unit, Okinawa Institute of Science and Technology Graduate University, 904-0495, Okinawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Murayama", 
        "givenName": "Takashi", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Okinawa Institute of Science and Technology", 
          "id": "https://www.grid.ac/institutes/grid.250464.1", 
          "name": [
            "Information Processing Biology Unit, Okinawa Institute of Science and Technology Graduate University, 904-0495, Okinawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Saita", 
        "givenName": "Ei-ichiro", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Okinawa Institute of Science and Technology", 
          "id": "https://www.grid.ac/institutes/grid.250464.1", 
          "name": [
            "Information Processing Biology Unit, Okinawa Institute of Science and Technology Graduate University, 904-0495, Okinawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Momohara", 
        "givenName": "Yuto", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Okinawa Institute of Science and Technology", 
          "id": "https://www.grid.ac/institutes/grid.250464.1", 
          "name": [
            "Neurobiology Research Unit, Okinawa Institute of Science and Technology Graduate University, 904-0495, Okinawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wickens", 
        "givenName": "Jeffery R.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Okinawa Institute of Science and Technology", 
          "id": "https://www.grid.ac/institutes/grid.250464.1", 
          "name": [
            "Information Processing Biology Unit, Okinawa Institute of Science and Technology Graduate University, 904-0495, Okinawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maruyama", 
        "givenName": "Ichiro N.", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/s0896-6273(01)00276-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000284162"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1124/pr.57.4.13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001425123"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.3633-08.2009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001545130"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pbio.0060055", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003225358"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nn.2157", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003762110", 
          "https://doi.org/10.1038/nn.2157"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nn1362", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004779862", 
          "https://doi.org/10.1038/nn1362"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nn1362", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004779862", 
          "https://doi.org/10.1038/nn1362"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1124/pr.57.4.5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005056946"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/sj.emboj.7600940", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006966219"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/sj.emboj.7600940", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006966219"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0896-6273(00)81014-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009563057"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1162/08997660152002852", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009962342"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3389/fendo.2016.00173", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011141249"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuron.2014.05.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011479879"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1098/rstb.1986.0056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012123360"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nn.2131", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013191587", 
          "https://doi.org/10.1038/nn.2131"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature06927", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013716015", 
          "https://doi.org/10.1038/nature06927"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0896-6273(02)00607-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017804367"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3389/fnsys.2015.00151", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018728933"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1242/jeb.01616", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019232181"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.tins.2013.04.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019903065"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1318325110", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021403390"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nn.4157", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022542373", 
          "https://doi.org/10.1038/nn.4157"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/375073a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024798477", 
          "https://doi.org/10.1038/375073a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/375073a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024798477", 
          "https://doi.org/10.1038/375073a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/neu.20261", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025963071"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jphysiol.2010.200683", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026501163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jphysiol.2010.200683", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026501163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cub.2009.05.043", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026737734"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuron.2011.06.038", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027708582"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1242/jeb.01615", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028973915"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1742-4658.2010.07658.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029605940"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.tins.2014.11.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030148587"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.282.5396.2028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031687391"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nn.2155", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031777853", 
          "https://doi.org/10.1038/nn.2155"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-8993(99)01111-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034825302"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nn.2540", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035086621", 
          "https://doi.org/10.1038/nn.2540"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nn.2540", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035086621", 
          "https://doi.org/10.1038/nn.2540"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0896-6273(94)90207-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038647744"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cne.901600305", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041406915"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.celrep.2015.08.032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041796541"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.celrep.2015.08.032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041796541"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.physbeh.2007.05.055", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042240954"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2007.02.041", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044094821"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cub.2013.04.052", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044689467"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature04657", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044942696", 
          "https://doi.org/10.1038/nature04657"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature04657", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044942696", 
          "https://doi.org/10.1038/nature04657"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature04657", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044942696", 
          "https://doi.org/10.1038/nature04657"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cub.2007.02.037", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044960867"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1534/genetics.110.119768", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045841842"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1534/genetics.110.119768", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045841842"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncomms6155", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045945732", 
          "https://doi.org/10.1038/ncomms6155"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0031614", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048709276"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0903570106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048757892"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncomms1304", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048781082", 
          "https://doi.org/10.1038/ncomms1304"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1534/genetics.113.152660", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049169801"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1534/genetics.113.152660", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049169801"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jphysiol.2012.245464", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050194730"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0896-6273(91)90276-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051259830"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1012346108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051290814"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.96.25.14600", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051834772"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi010580s", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055193770"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi010580s", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055193770"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1534/genetics.115.177543", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1067739425"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1534/genetics.115.177543", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1067739425"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1534/genetics.115.177543", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1067739425"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074695921", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.23-16-06537.2003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1075320688"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075810908", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.09-02-00415.1989", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079037932"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.09-02-00403.1989", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079453843"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080300025", 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncomms14818", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084129017", 
          "https://doi.org/10.1038/ncomms14818"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2018.08.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1106967848"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-12", 
    "datePublishedReg": "2019-12-01", 
    "description": "Active propagation of electrical signals in C. elegans neurons requires ion channels capable of regenerating membrane potentials. Here we report regenerative depolarization of a major gustatory sensory neuron, ASEL. Whole-cell patch-clamp recordings in vivo showed supralinear depolarization of ASEL upon current injection. Furthermore, stimulation of animal's nose with NaCl evoked all-or-none membrane depolarization in ASEL. Mutant analysis showed that EGL-19, the \u03b11 subunit of L-type voltage-gated Ca2+ channels, is essential for regenerative depolarization of ASEL. ASEL-specific knock-down of EGL-19 by RNAi demonstrated that EGL-19 functions in C. elegans chemotaxis along an NaCl gradient. These results demonstrate that a natural substance induces regenerative all-or-none electrical signals in dendrites, and that these signals are essential for activation of sensory neurons for chemotaxis. As in other vertebrate and invertebrate nervous systems, active information processing in dendrites occurs in C. elegans, and is necessary for adaptive behavior.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/s41598-019-40158-9", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1045337", 
        "issn": [
          "2045-2322"
        ], 
        "name": "Scientific Reports", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "9"
      }
    ], 
    "name": "Active propagation of dendritic electrical signals in C. elegans", 
    "pagination": "3430", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "42a11e6e6f401f57113e1cba918ed75ed315c5b9bea74b3519e8a252e29ccc9a"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30837592"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101563288"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s41598-019-40158-9"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1112544068"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s41598-019-40158-9", 
      "https://app.dimensions.ai/details/publication/pub.1112544068"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T11:21", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000354_0000000354/records_11726_00000002.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/s41598-019-40158-9"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41598-019-40158-9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41598-019-40158-9'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41598-019-40158-9'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41598-019-40158-9'


 

This table displays all metadata directly associated to this object as RDF triples.

296 TRIPLES      21 PREDICATES      90 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s41598-019-40158-9 schema:about anzsrc-for:11
2 anzsrc-for:1109
3 schema:author Na9853e00c17645858f9bbae948eb92bf
4 schema:citation sg:pub.10.1038/375073a0
5 sg:pub.10.1038/nature04657
6 sg:pub.10.1038/nature06927
7 sg:pub.10.1038/ncomms1304
8 sg:pub.10.1038/ncomms14818
9 sg:pub.10.1038/ncomms6155
10 sg:pub.10.1038/nn.2131
11 sg:pub.10.1038/nn.2155
12 sg:pub.10.1038/nn.2157
13 sg:pub.10.1038/nn.2540
14 sg:pub.10.1038/nn.4157
15 sg:pub.10.1038/nn1362
16 https://app.dimensions.ai/details/publication/pub.1074695921
17 https://app.dimensions.ai/details/publication/pub.1075810908
18 https://app.dimensions.ai/details/publication/pub.1080300025
19 https://doi.org/10.1002/cne.901600305
20 https://doi.org/10.1002/neu.20261
21 https://doi.org/10.1016/0896-6273(91)90276-6
22 https://doi.org/10.1016/0896-6273(94)90207-0
23 https://doi.org/10.1016/j.cell.2007.02.041
24 https://doi.org/10.1016/j.cell.2018.08.018
25 https://doi.org/10.1016/j.celrep.2015.08.032
26 https://doi.org/10.1016/j.cub.2007.02.037
27 https://doi.org/10.1016/j.cub.2009.05.043
28 https://doi.org/10.1016/j.cub.2013.04.052
29 https://doi.org/10.1016/j.neuron.2011.06.038
30 https://doi.org/10.1016/j.neuron.2014.05.010
31 https://doi.org/10.1016/j.physbeh.2007.05.055
32 https://doi.org/10.1016/j.tins.2013.04.006
33 https://doi.org/10.1016/j.tins.2014.11.002
34 https://doi.org/10.1016/s0006-8993(99)01111-7
35 https://doi.org/10.1016/s0896-6273(00)81014-4
36 https://doi.org/10.1016/s0896-6273(01)00276-8
37 https://doi.org/10.1016/s0896-6273(02)00607-4
38 https://doi.org/10.1021/bi010580s
39 https://doi.org/10.1038/sj.emboj.7600940
40 https://doi.org/10.1073/pnas.0903570106
41 https://doi.org/10.1073/pnas.1012346108
42 https://doi.org/10.1073/pnas.1318325110
43 https://doi.org/10.1073/pnas.96.25.14600
44 https://doi.org/10.1098/rstb.1986.0056
45 https://doi.org/10.1111/j.1742-4658.2010.07658.x
46 https://doi.org/10.1113/jphysiol.2010.200683
47 https://doi.org/10.1113/jphysiol.2012.245464
48 https://doi.org/10.1124/pr.57.4.13
49 https://doi.org/10.1124/pr.57.4.5
50 https://doi.org/10.1126/science.282.5396.2028
51 https://doi.org/10.1162/08997660152002852
52 https://doi.org/10.1242/jeb.01615
53 https://doi.org/10.1242/jeb.01616
54 https://doi.org/10.1371/journal.pbio.0060055
55 https://doi.org/10.1371/journal.pone.0031614
56 https://doi.org/10.1523/jneurosci.09-02-00403.1989
57 https://doi.org/10.1523/jneurosci.09-02-00415.1989
58 https://doi.org/10.1523/jneurosci.23-16-06537.2003
59 https://doi.org/10.1523/jneurosci.3633-08.2009
60 https://doi.org/10.1534/genetics.110.119768
61 https://doi.org/10.1534/genetics.113.152660
62 https://doi.org/10.1534/genetics.115.177543
63 https://doi.org/10.3389/fendo.2016.00173
64 https://doi.org/10.3389/fnsys.2015.00151
65 schema:datePublished 2019-12
66 schema:datePublishedReg 2019-12-01
67 schema:description Active propagation of electrical signals in C. elegans neurons requires ion channels capable of regenerating membrane potentials. Here we report regenerative depolarization of a major gustatory sensory neuron, ASEL. Whole-cell patch-clamp recordings in vivo showed supralinear depolarization of ASEL upon current injection. Furthermore, stimulation of animal's nose with NaCl evoked all-or-none membrane depolarization in ASEL. Mutant analysis showed that EGL-19, the α1 subunit of L-type voltage-gated Ca<sup>2+</sup> channels, is essential for regenerative depolarization of ASEL. ASEL-specific knock-down of EGL-19 by RNAi demonstrated that EGL-19 functions in C. elegans chemotaxis along an NaCl gradient. These results demonstrate that a natural substance induces regenerative all-or-none electrical signals in dendrites, and that these signals are essential for activation of sensory neurons for chemotaxis. As in other vertebrate and invertebrate nervous systems, active information processing in dendrites occurs in C. elegans, and is necessary for adaptive behavior.
68 schema:genre research_article
69 schema:inLanguage en
70 schema:isAccessibleForFree true
71 schema:isPartOf Nd83b728d827e4087a38fe0b8cea475aa
72 Nff5f2b06bff449469dccf2bad1dcb827
73 sg:journal.1045337
74 schema:name Active propagation of dendritic electrical signals in C. elegans
75 schema:pagination 3430
76 schema:productId N59eeab1a0a06453b9081f1bbcd0fd732
77 Nd77adb5acaf84e4582d639b9efd81678
78 Ndd75f6555a04489fb809cc2085e80916
79 Nde715a44aad9454c85750f2de69a9718
80 Nf9e77c61f6764970a9c9d365ae27f32a
81 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112544068
82 https://doi.org/10.1038/s41598-019-40158-9
83 schema:sdDatePublished 2019-04-11T11:21
84 schema:sdLicense https://scigraph.springernature.com/explorer/license/
85 schema:sdPublisher Nb961a79a3e704fefb747e4f28d24bfd3
86 schema:url https://www.nature.com/articles/s41598-019-40158-9
87 sgo:license sg:explorer/license/
88 sgo:sdDataset articles
89 rdf:type schema:ScholarlyArticle
90 N024e98fc189d4b458c69621f059a54d3 schema:affiliation https://www.grid.ac/institutes/grid.250464.1
91 schema:familyName Maruyama
92 schema:givenName Ichiro N.
93 rdf:type schema:Person
94 N03eed6c8ca1e4604b2ce47deb4fc9c35 schema:affiliation https://www.grid.ac/institutes/grid.250464.1
95 schema:familyName Murayama
96 schema:givenName Takashi
97 rdf:type schema:Person
98 N13cab517d6fa436d8ace97533fa3ea83 rdf:first Nf5b9e44600194f33811f3c9a34e76467
99 rdf:rest N6b0e63a83b2546a8b04279f12b1e8332
100 N196d1e5be51a46b58ae9d162018fcd48 schema:affiliation https://www.grid.ac/institutes/grid.250464.1
101 schema:familyName Saita
102 schema:givenName Ei-ichiro
103 rdf:type schema:Person
104 N539696b9e30348079ff3bfcea077d3af rdf:first N03eed6c8ca1e4604b2ce47deb4fc9c35
105 rdf:rest Ndc4fcf9dff1f48c387ae30d1de262cfa
106 N59eeab1a0a06453b9081f1bbcd0fd732 schema:name doi
107 schema:value 10.1038/s41598-019-40158-9
108 rdf:type schema:PropertyValue
109 N6b0e63a83b2546a8b04279f12b1e8332 rdf:first N91ef01395a1b4270a058646c36e1c202
110 rdf:rest N75fada5dc4704abd8c3ebe2650372c77
111 N75fada5dc4704abd8c3ebe2650372c77 rdf:first N024e98fc189d4b458c69621f059a54d3
112 rdf:rest rdf:nil
113 N78936e3db6cf4875bf8b2079454271e4 schema:affiliation https://www.grid.ac/institutes/grid.250464.1
114 schema:familyName Shindou
115 schema:givenName Tomomi
116 rdf:type schema:Person
117 N91ef01395a1b4270a058646c36e1c202 schema:affiliation https://www.grid.ac/institutes/grid.250464.1
118 schema:familyName Wickens
119 schema:givenName Jeffery R.
120 rdf:type schema:Person
121 Na5e03aff9ad4476d8a5da56700a7f865 rdf:first Nf38767c233114362803658b161560da5
122 rdf:rest N539696b9e30348079ff3bfcea077d3af
123 Na9853e00c17645858f9bbae948eb92bf rdf:first N78936e3db6cf4875bf8b2079454271e4
124 rdf:rest Na5e03aff9ad4476d8a5da56700a7f865
125 Nb961a79a3e704fefb747e4f28d24bfd3 schema:name Springer Nature - SN SciGraph project
126 rdf:type schema:Organization
127 Nd77adb5acaf84e4582d639b9efd81678 schema:name dimensions_id
128 schema:value pub.1112544068
129 rdf:type schema:PropertyValue
130 Nd83b728d827e4087a38fe0b8cea475aa schema:volumeNumber 9
131 rdf:type schema:PublicationVolume
132 Ndc4fcf9dff1f48c387ae30d1de262cfa rdf:first N196d1e5be51a46b58ae9d162018fcd48
133 rdf:rest N13cab517d6fa436d8ace97533fa3ea83
134 Ndd75f6555a04489fb809cc2085e80916 schema:name readcube_id
135 schema:value 42a11e6e6f401f57113e1cba918ed75ed315c5b9bea74b3519e8a252e29ccc9a
136 rdf:type schema:PropertyValue
137 Nde715a44aad9454c85750f2de69a9718 schema:name pubmed_id
138 schema:value 30837592
139 rdf:type schema:PropertyValue
140 Nf38767c233114362803658b161560da5 schema:affiliation https://www.grid.ac/institutes/grid.250464.1
141 schema:familyName Ochi-Shindou
142 schema:givenName Mayumi
143 rdf:type schema:Person
144 Nf5b9e44600194f33811f3c9a34e76467 schema:affiliation https://www.grid.ac/institutes/grid.250464.1
145 schema:familyName Momohara
146 schema:givenName Yuto
147 rdf:type schema:Person
148 Nf9e77c61f6764970a9c9d365ae27f32a schema:name nlm_unique_id
149 schema:value 101563288
150 rdf:type schema:PropertyValue
151 Nff5f2b06bff449469dccf2bad1dcb827 schema:issueNumber 1
152 rdf:type schema:PublicationIssue
153 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
154 schema:name Medical and Health Sciences
155 rdf:type schema:DefinedTerm
156 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
157 schema:name Neurosciences
158 rdf:type schema:DefinedTerm
159 sg:journal.1045337 schema:issn 2045-2322
160 schema:name Scientific Reports
161 rdf:type schema:Periodical
162 sg:pub.10.1038/375073a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024798477
163 https://doi.org/10.1038/375073a0
164 rdf:type schema:CreativeWork
165 sg:pub.10.1038/nature04657 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044942696
166 https://doi.org/10.1038/nature04657
167 rdf:type schema:CreativeWork
168 sg:pub.10.1038/nature06927 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013716015
169 https://doi.org/10.1038/nature06927
170 rdf:type schema:CreativeWork
171 sg:pub.10.1038/ncomms1304 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048781082
172 https://doi.org/10.1038/ncomms1304
173 rdf:type schema:CreativeWork
174 sg:pub.10.1038/ncomms14818 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084129017
175 https://doi.org/10.1038/ncomms14818
176 rdf:type schema:CreativeWork
177 sg:pub.10.1038/ncomms6155 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045945732
178 https://doi.org/10.1038/ncomms6155
179 rdf:type schema:CreativeWork
180 sg:pub.10.1038/nn.2131 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013191587
181 https://doi.org/10.1038/nn.2131
182 rdf:type schema:CreativeWork
183 sg:pub.10.1038/nn.2155 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031777853
184 https://doi.org/10.1038/nn.2155
185 rdf:type schema:CreativeWork
186 sg:pub.10.1038/nn.2157 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003762110
187 https://doi.org/10.1038/nn.2157
188 rdf:type schema:CreativeWork
189 sg:pub.10.1038/nn.2540 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035086621
190 https://doi.org/10.1038/nn.2540
191 rdf:type schema:CreativeWork
192 sg:pub.10.1038/nn.4157 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022542373
193 https://doi.org/10.1038/nn.4157
194 rdf:type schema:CreativeWork
195 sg:pub.10.1038/nn1362 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004779862
196 https://doi.org/10.1038/nn1362
197 rdf:type schema:CreativeWork
198 https://app.dimensions.ai/details/publication/pub.1074695921 schema:CreativeWork
199 https://app.dimensions.ai/details/publication/pub.1075810908 schema:CreativeWork
200 https://app.dimensions.ai/details/publication/pub.1080300025 schema:CreativeWork
201 https://doi.org/10.1002/cne.901600305 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041406915
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1002/neu.20261 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025963071
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1016/0896-6273(91)90276-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051259830
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1016/0896-6273(94)90207-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038647744
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1016/j.cell.2007.02.041 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044094821
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1016/j.cell.2018.08.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106967848
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1016/j.celrep.2015.08.032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041796541
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1016/j.cub.2007.02.037 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044960867
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1016/j.cub.2009.05.043 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026737734
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1016/j.cub.2013.04.052 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044689467
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1016/j.neuron.2011.06.038 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027708582
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1016/j.neuron.2014.05.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011479879
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1016/j.physbeh.2007.05.055 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042240954
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1016/j.tins.2013.04.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019903065
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1016/j.tins.2014.11.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030148587
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1016/s0006-8993(99)01111-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034825302
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1016/s0896-6273(00)81014-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009563057
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1016/s0896-6273(01)00276-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000284162
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1016/s0896-6273(02)00607-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017804367
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1021/bi010580s schema:sameAs https://app.dimensions.ai/details/publication/pub.1055193770
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1038/sj.emboj.7600940 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006966219
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1073/pnas.0903570106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048757892
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1073/pnas.1012346108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051290814
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1073/pnas.1318325110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021403390
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1073/pnas.96.25.14600 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051834772
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1098/rstb.1986.0056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012123360
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1111/j.1742-4658.2010.07658.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1029605940
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1113/jphysiol.2010.200683 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026501163
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1113/jphysiol.2012.245464 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050194730
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1124/pr.57.4.13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001425123
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1124/pr.57.4.5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005056946
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1126/science.282.5396.2028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031687391
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1162/08997660152002852 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009962342
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1242/jeb.01615 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028973915
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1242/jeb.01616 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019232181
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1371/journal.pbio.0060055 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003225358
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1371/journal.pone.0031614 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048709276
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1523/jneurosci.09-02-00403.1989 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079453843
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1523/jneurosci.09-02-00415.1989 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079037932
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1523/jneurosci.23-16-06537.2003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075320688
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1523/jneurosci.3633-08.2009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001545130
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1534/genetics.110.119768 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045841842
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1534/genetics.113.152660 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049169801
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1534/genetics.115.177543 schema:sameAs https://app.dimensions.ai/details/publication/pub.1067739425
288 rdf:type schema:CreativeWork
289 https://doi.org/10.3389/fendo.2016.00173 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011141249
290 rdf:type schema:CreativeWork
291 https://doi.org/10.3389/fnsys.2015.00151 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018728933
292 rdf:type schema:CreativeWork
293 https://www.grid.ac/institutes/grid.250464.1 schema:alternateName Okinawa Institute of Science and Technology
294 schema:name Information Processing Biology Unit, Okinawa Institute of Science and Technology Graduate University, 904-0495, Okinawa, Japan
295 Neurobiology Research Unit, Okinawa Institute of Science and Technology Graduate University, 904-0495, Okinawa, Japan
296 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...