Involvement of TRPM2 and TRPM8 in temperature-dependent masking behavior View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Wataru Ota, Yusuke Nakane, Makiko Kashio, Yoshiro Suzuki, Kazuhiro Nakamura, Yasuo Mori, Makoto Tominaga, Takashi Yoshimura

ABSTRACT

Masking is a direct behavioral response to environmental changes and plays an important role in the temporal distribution of activity. However, the mechanisms responsible for masking remain unclear. Here we identify thermosensors and a possible neural circuit regulating temperature-dependent masking behavior in mice. Analysis of mice lacking thermosensitive transient receptor potential (TRP) channels (Trpv1/3/4 and Trpm2/8) reveals that temperature-dependent masking is impaired in Trpm2- and Trpm8-null mice. Several brain regions are activated during temperature-dependent masking, including the preoptic area (POA), known as the thermoregulatory center, the suprachiasmatic nucleus (SCN), which is the primary circadian pacemaker, the paraventricular nucleus of the thalamus (PVT), and the nucleus accumbens (NAc). The POA, SCN, PVT are interconnected, and the PVT sends dense projections to the NAc, a key brain region involved in wheel-running activity. Partial chemical lesion of the PVT attenuates masking, suggesting the involvement of the PVT in temperature-dependent masking behavior. More... »

PAGES

3706

References to SciGraph publications

  • 2003-07. Melanopsin and rod–cone photoreceptive systems account for all major accessory visual functions in mice in NATURE
  • 2007-07. The menthol receptor TRPM8 is the principal detector of environmental cold in NATURE
  • 2002-03. Identification of a cold receptor reveals a general role for TRP channels in thermosensation in NATURE
  • 1911-02. Beiträge zur Physiologie der Pigmentzellen in der Fischhaut in PFLÜGERS ARCHIV - EUROPEAN JOURNAL OF PHYSIOLOGY
  • 1969-08. Die relative Wirksamkeit von Zeitgebern in OECOLOGIA
  • 2005-11. Diurnal mice (Mus musculus) and other examples of temporal niche switching in JOURNAL OF COMPARATIVE PHYSIOLOGY A
  • 1979-09. Spectral characteristics of visible radiation penetrating into the brain and stimulating extraretinal photoreceptors in JOURNAL OF COMPARATIVE PHYSIOLOGY A
  • 1981-01. Functional absence of brain photoreceptors mediating entrainment of circadian rhythms in the adult rat in CELLULAR AND MOLECULAR LIFE SCIENCES
  • 2016-08. The TRPM2 ion channel is required for sensitivity to warmth in NATURE
  • 2012-04-04. Unexpected features of Drosophila circadian behavioural rhythms under natural conditions in NATURE
  • 2012-04. Sources of inputs to the anterior and posterior aspects of the paraventricular nucleus of the thalamus in BRAIN STRUCTURE AND FUNCTION
  • 2012-12. Transient receptor potential melastatin 8 (TRPM8) channels are involved in body temperature regulation in MOLECULAR PAIN
  • 2017-12. The lateral parabrachial nucleus, but not the thalamus, mediates thermosensory pathways for behavioural thermoregulation in SCIENTIFIC REPORTS
  • 1999-05. Thresholds for masking responses to light in three strains of retinally degenerate mice in JOURNAL OF COMPARATIVE PHYSIOLOGY A
  • 2008-07. TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration in NATURE MEDICINE
  • 2003-07. ThermoTRP channels and beyond: mechanisms of temperature sensation in NATURE REVIEWS NEUROSCIENCE
  • 1999-05. Masking of locomotor activity in hamsters in JOURNAL OF COMPARATIVE PHYSIOLOGY A
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/s41598-019-40067-x

    DOI

    http://dx.doi.org/10.1038/s41598-019-40067-x

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1112573203

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30842533


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