Contribution to dose in healthy tissue from secondary target fragments in therapeutic proton, He and C beams measured with CR-39 ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Satoshi Kodaira, Hisashi Kitamura, Mieko Kurano, Hajime Kawashima, Eric R. Benton

ABSTRACT

The linear energy transfer (LET) spectrum, absorbed dose and dose equivalent from secondary particles of LETH2O ≥15 keV/μm deposited within the plateau of the Bragg curve in primary particle-induced nuclear target fragmentation reactions in tissue during proton and heavy ion radiotherapy were measured using CR-39 plastic nuclear track detectors and analyzed by means of atomic force microscopy. It was found that secondary target fragments contributed 20% to dose equivalent for primary protons (157 MeV), 13% for primary helium ions (145 MeV/n) and 4% for primary carbon ions (383 MeV/n), respectively. Little research has been done on the contribution from these particles to primary given dose. The smaller contribution measured for energetic carbon ion beams compared to proton beams can be considered an advantage of carbon ion radiotherapy over proton radiotherapy. More... »

PAGES

3708

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41598-019-39598-0

DOI

http://dx.doi.org/10.1038/s41598-019-39598-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112581317

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30842438


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