Transcriptional profiling of wheat (Triticum aestivum L.) during a compatible interaction with the cereal cyst nematode Heterodera avenae View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-02-18

AUTHORS

Fen Qiao, Ling-An Kong, Huan Peng, Wen-Kun Huang, Du-Qing Wu, Shi-Ming Liu, Jihong Liu Clarke, De-Wen Qiu, De-Liang Peng

ABSTRACT

Cereal cyst nematode (CCN, Heterodera avenae) presents severe challenges to wheat (Triticum aestivum L.) production worldwide. An investigation of the interaction between wheat and CCN can greatly improve our understanding of how nematodes alter wheat root metabolic pathways for their development and could contribute to new control strategies against CCN. In this study, we conducted transcriptome analyses of wheat cv. Wen 19 (Wen19) by using RNA-Seq during the compatible interaction with CCN at 1, 3 and 8 days past inoculation (dpi). In total, 71,569 transcripts were identified, and 10,929 of them were examined as differentially expressed genes (DEGs) in response to CCN infection. Based on the functional annotation and orthologous findings, the protein phosphorylation, oxidation-reduction process, regulation of transcription, metabolic process, transport, and response process as well as many other pathways previously reported were enriched at the transcriptional level. Plant cell wall hydrolysis and modifying proteins, auxin biosynthesis, signalling and transporter genes were up-regulated by CCN infection to facilitate penetration, migration and syncytium establishment. Genes responding to wounding and jasmonic acid stimuli were enriched at 1 dpi. We found 16 NBS-LRR genes, 12 of which were down-regulated, indicating the repression of resistance. The expression of genes encoding antioxidant enzymes, glutathione S-transferases and UDP-glucosyltransferase was significantly up-regulated during CCN infection, indicating that they may play key roles in the compatible interaction of wheat with CCN. Taken together, the results obtained from the transcriptome analyses indicate that the genes involved in oxidation-reduction processes, induction and suppression of resistance, metabolism, transport and syncytium establishment may be involved in the compatible interaction of Wen 19 with CCN. This study provides new insights into the responses of wheat to CCN infection. These insights could facilitate the elucidation of the potential mechanisms of wheat responses to CCN. More... »

PAGES

2184

References to SciGraph publications

  • 2012-04-11. De novo assembly and characterization of the root transcriptome of Aegilops variabilis during an interaction with the cereal cyst nematode in BMC GENOMICS
  • 2007-08-01. Laser capture microdissection (LCM) and comparative microarray expression analysis of syncytial cells isolated from incompatible and compatible soybean (Glycine max) roots infected by the soybean cyst nematode (Heterodera glycines) in PLANTA
  • 2015-10-16. Large-scale identification of wheat genes resistant to cereal cyst nematode Heterodera avenae using comparative transcriptomic analysis in BMC GENOMICS
  • 2013-07-11. De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis in NATURE PROTOCOLS
  • 2017-11-03. Transcriptional responses of wheat and the cereal cyst nematode Heterodera avenae during their early contact stage in SCIENTIFIC REPORTS
  • 2017-05-02. Gene expression profiling describes the genetic regulation of Meloidogyne arenaria resistance in Arachis hypogaea and reveals a candidate gene for resistance in SCIENTIFIC REPORTS
  • 2011-03-18. ROS and NO production in compatible and incompatible tomato-Meloidogyne incognita interactions in EUROPEAN JOURNAL OF PLANT PATHOLOGY
  • 2017-05-08. Metabolism of the plant hormone jasmonate: a sentinel for tissue damage and master regulator of stress response in PHYTOCHEMISTRY REVIEWS
  • 2015-03-04. Whole-genome gene expression profiling revealed genes and pathways potentially involved in regulating interactions of soybean with cyst nematode (Heterodera glycines Ichinohe) in BMC GENOMICS
  • 2011-05-10. Analysis of Gene expression in soybean (Glycine max) roots in response to the root knot nematode Meloidogyne incognita using microarrays and KEGG pathways in BMC GENOMICS
  • 1996-07. Genetic variation in natural populations of the cereal cyst nematode (Heterodera avenae Woll.) submitted to resistant and susceptible cultivars of cereals in THEORETICAL AND APPLIED GENETICS
  • 2012-10-15. A soybean cyst nematode resistance gene points to a new mechanism of plant resistance to pathogens in NATURE
  • 2006-03-31. Timecourse microarray analyses reveal global changes in gene expression of susceptible Glycine max (soybean) roots during infection by Heterodera glycines (soybean cyst nematode) in PLANTA
  • 2017-08-29. Comparative RNA-Seq Analysis Uncovers a Complex Regulatory Network for Soybean Cyst Nematode Resistance in Wild Soybean (Glycine soja) in SCIENTIFIC REPORTS
  • 2012-03-01. Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks in NATURE PROTOCOLS
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/s41598-018-37824-9

    DOI

    http://dx.doi.org/10.1038/s41598-018-37824-9

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1112201159

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30778126


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biochemistry and Cell Biology", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Genetics", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animals", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Edible Grain", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Gene Expression Profiling", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Gene Expression Regulation, Plant", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genes, Plant", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Host-Parasite Interactions", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Metabolic Networks and Pathways", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Plant Diseases", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Plant Growth Regulators", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Plant Roots", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "RNA-Seq", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Triticum", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Tylenchoidea", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China", 
              "id": "http://www.grid.ac/institutes/grid.464356.6", 
              "name": [
                "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Qiao", 
            "givenName": "Fen", 
            "id": "sg:person.013134417135.36", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013134417135.36"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China", 
              "id": "http://www.grid.ac/institutes/grid.464356.6", 
              "name": [
                "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kong", 
            "givenName": "Ling-An", 
            "id": "sg:person.0602256473.30", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602256473.30"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China", 
              "id": "http://www.grid.ac/institutes/grid.464356.6", 
              "name": [
                "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Peng", 
            "givenName": "Huan", 
            "id": "sg:person.01257547373.17", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257547373.17"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China", 
              "id": "http://www.grid.ac/institutes/grid.464356.6", 
              "name": [
                "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Huang", 
            "givenName": "Wen-Kun", 
            "id": "sg:person.0716505073.40", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0716505073.40"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China", 
              "id": "http://www.grid.ac/institutes/grid.464356.6", 
              "name": [
                "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wu", 
            "givenName": "Du-Qing", 
            "id": "sg:person.0643014415.89", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0643014415.89"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China", 
              "id": "http://www.grid.ac/institutes/grid.464356.6", 
              "name": [
                "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Liu", 
            "givenName": "Shi-Ming", 
            "id": "sg:person.01141604615.18", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141604615.18"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "NIBIO - Norwegian Institute of Bioeconomy Research, P.O. Box 115, N-1431 Oslo, \u00c5s Norway", 
              "id": "http://www.grid.ac/institutes/grid.454322.6", 
              "name": [
                "NIBIO - Norwegian Institute of Bioeconomy Research, P.O. Box 115, N-1431 Oslo, \u00c5s Norway"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Clarke", 
            "givenName": "Jihong Liu", 
            "id": "sg:person.01234620657.87", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01234620657.87"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China", 
              "id": "http://www.grid.ac/institutes/grid.464356.6", 
              "name": [
                "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Qiu", 
            "givenName": "De-Wen", 
            "id": "sg:person.01231301336.89", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01231301336.89"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China", 
              "id": "http://www.grid.ac/institutes/grid.464356.6", 
              "name": [
                "State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Peng", 
            "givenName": "De-Liang", 
            "id": "sg:person.01101046673.18", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101046673.18"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/s41598-017-14047-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092446397", 
              "https://doi.org/10.1038/s41598-017-14047-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1471-2164-12-220", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019568148", 
              "https://doi.org/10.1186/1471-2164-12-220"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00225719", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026471846", 
              "https://doi.org/10.1007/bf00225719"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1471-2164-13-133", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051919581", 
              "https://doi.org/10.1186/1471-2164-13-133"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11101-017-9510-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085211067", 
              "https://doi.org/10.1007/s11101-017-9510-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00425-007-0578-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021610920", 
              "https://doi.org/10.1007/s00425-007-0578-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00425-006-0270-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003825232", 
              "https://doi.org/10.1007/s00425-006-0270-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nprot.2012.016", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030124536", 
              "https://doi.org/10.1038/nprot.2012.016"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12864-015-1316-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011509578", 
              "https://doi.org/10.1186/s12864-015-1316-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12864-015-2037-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051848897", 
              "https://doi.org/10.1186/s12864-015-2037-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nprot.2013.084", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051115056", 
              "https://doi.org/10.1038/nprot.2013.084"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41598-017-09945-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1091313414", 
              "https://doi.org/10.1038/s41598-017-09945-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10658-011-9768-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028221524", 
              "https://doi.org/10.1007/s10658-011-9768-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41598-017-00971-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085114463", 
              "https://doi.org/10.1038/s41598-017-00971-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature11651", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046632196", 
              "https://doi.org/10.1038/nature11651"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2019-02-18", 
        "datePublishedReg": "2019-02-18", 
        "description": "Cereal cyst nematode (CCN, Heterodera avenae) presents severe challenges to wheat (Triticum aestivum L.) production worldwide. An investigation of the interaction between wheat and CCN can greatly improve our understanding of how nematodes alter wheat root metabolic pathways for their development and could contribute to new control strategies against CCN. In this study, we conducted transcriptome analyses of wheat cv. Wen 19 (Wen19) by using RNA-Seq during the compatible interaction with CCN at 1, 3 and 8 days past inoculation (dpi). In total, 71,569 transcripts were identified, and 10,929 of them were examined as differentially expressed genes (DEGs) in response to CCN infection. Based on the functional annotation and orthologous findings, the protein phosphorylation, oxidation-reduction process, regulation of transcription, metabolic process, transport, and response process as well as many other pathways previously reported were enriched at the transcriptional level. Plant cell wall hydrolysis and modifying proteins, auxin biosynthesis, signalling and transporter genes were up-regulated by CCN infection to facilitate penetration, migration and syncytium establishment. Genes responding to wounding and jasmonic acid stimuli were enriched at 1 dpi. We found 16 NBS-LRR genes, 12 of which were down-regulated, indicating the repression of resistance. The expression of genes encoding antioxidant enzymes, glutathione S-transferases and UDP-glucosyltransferase was significantly up-regulated during CCN infection, indicating that they may play key roles in the compatible interaction of wheat with CCN. Taken together, the results obtained from the transcriptome analyses indicate that the genes involved in oxidation-reduction processes, induction and suppression of resistance, metabolism, transport and syncytium establishment may be involved in the compatible interaction of Wen 19 with CCN. This study provides new insights into the responses of wheat to CCN infection. These insights could facilitate the elucidation of the potential mechanisms of wheat responses to CCN.", 
        "genre": "article", 
        "id": "sg:pub.10.1038/s41598-018-37824-9", 
        "inLanguage": "en", 
        "isAccessibleForFree": true, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.8191443", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1045337", 
            "issn": [
              "2045-2322"
            ], 
            "name": "Scientific Reports", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "9"
          }
        ], 
        "keywords": [
          "CCN infection", 
          "compatible interaction", 
          "transcriptome analysis", 
          "oxidation-reduction process", 
          "cereal cyst nematode Heterodera avenae", 
          "plant cell wall hydrolysis", 
          "jasmonic acid stimulus", 
          "NBS-LRR genes", 
          "regulation of transcription", 
          "cell wall hydrolysis", 
          "cereal cyst nematode", 
          "expression of genes", 
          "auxin biosynthesis", 
          "functional annotation", 
          "wall hydrolysis", 
          "protein phosphorylation", 
          "transcriptional profiling", 
          "RNA-seq", 
          "Heterodera avenae", 
          "transcriptional level", 
          "cyst nematode", 
          "wheat cv", 
          "transporter gene", 
          "UDP-glucosyltransferase", 
          "response of wheat", 
          "metabolic processes", 
          "metabolic pathways", 
          "genes", 
          "wheat response", 
          "glutathione S", 
          "wheat", 
          "antioxidant enzymes", 
          "nematodes", 
          "new insights", 
          "pathway", 
          "key role", 
          "acid stimuli", 
          "potential mechanisms", 
          "repression of resistance", 
          "transcription", 
          "repression", 
          "biosynthesis", 
          "avenae", 
          "suppression of resistance", 
          "phosphorylation", 
          "transcripts", 
          "signaling", 
          "wounding", 
          "protein", 
          "interaction", 
          "enzyme", 
          "establishment", 
          "profiling", 
          "regulation", 
          "transferase", 
          "insights", 
          "annotation", 
          "elucidation", 
          "expression", 
          "metabolism", 
          "transport", 
          "response", 
          "inoculation", 
          "induction", 
          "resistance", 
          "response process", 
          "cv", 
          "migration", 
          "hydrolysis", 
          "infection", 
          "mechanism", 
          "role", 
          "production", 
          "dpi", 
          "suppression", 
          "process", 
          "analysis", 
          "understanding", 
          "CCN", 
          "new control strategy", 
          "development", 
          "levels", 
          "study", 
          "stimuli", 
          "strategies", 
          "findings", 
          "total", 
          "results", 
          "severe challenges", 
          "investigation", 
          "days", 
          "control strategy", 
          "penetration", 
          "challenges", 
          "wheat root metabolic pathways", 
          "root metabolic pathways", 
          "Wen 19", 
          "orthologous findings", 
          "syncytium establishment", 
          "cyst nematode Heterodera avenae", 
          "nematode Heterodera avenae"
        ], 
        "name": "Transcriptional profiling of wheat (Triticum aestivum L.) during a compatible interaction with the cereal cyst nematode Heterodera avenae", 
        "pagination": "2184", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1112201159"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/s41598-018-37824-9"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "30778126"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/s41598-018-37824-9", 
          "https://app.dimensions.ai/details/publication/pub.1112201159"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-01-01T18:53", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_805.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1038/s41598-018-37824-9"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-37824-9'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-37824-9'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-37824-9'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-37824-9'


     

    This table displays all metadata directly associated to this object as RDF triples.

    339 TRIPLES      22 PREDICATES      156 URIs      132 LITERALS      20 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/s41598-018-37824-9 schema:about N1910c8ed38e944ff8ff2559431231fdf
    2 N2e1589032fa944358444b06f2ed8f989
    3 N636522805cc24436b1f28e69efaef1d8
    4 N6a18cbc251474e6a93df1b90210f2d76
    5 N6b91473d02d449ffa0c267274f263c79
    6 N75be0181e61748c3b5cd0d65a6037717
    7 N84fe06e51e1948039eae622ea0f82602
    8 N90bcf125e2c24a038798d09c7afb2e4d
    9 Na1dda6eb4a75481bb5c2bf8afd32836a
    10 Nd097ff31660d48d5835b026765682c1b
    11 Nd21f786fd9ab428eb7363e0edf9ac5fb
    12 Nd3cfe90c1fd94bf88de8d7e07393b0a3
    13 Ne6c9cbcba2b64307bfb5305da6106c31
    14 anzsrc-for:06
    15 anzsrc-for:0601
    16 anzsrc-for:0604
    17 schema:author Nd8ccd7764f67472c894a04f0d124b7bb
    18 schema:citation sg:pub.10.1007/bf00225719
    19 sg:pub.10.1007/s00425-006-0270-8
    20 sg:pub.10.1007/s00425-007-0578-z
    21 sg:pub.10.1007/s10658-011-9768-4
    22 sg:pub.10.1007/s11101-017-9510-8
    23 sg:pub.10.1038/nature11651
    24 sg:pub.10.1038/nprot.2012.016
    25 sg:pub.10.1038/nprot.2013.084
    26 sg:pub.10.1038/s41598-017-00971-6
    27 sg:pub.10.1038/s41598-017-09945-0
    28 sg:pub.10.1038/s41598-017-14047-y
    29 sg:pub.10.1186/1471-2164-12-220
    30 sg:pub.10.1186/1471-2164-13-133
    31 sg:pub.10.1186/s12864-015-1316-8
    32 sg:pub.10.1186/s12864-015-2037-8
    33 schema:datePublished 2019-02-18
    34 schema:datePublishedReg 2019-02-18
    35 schema:description Cereal cyst nematode (CCN, Heterodera avenae) presents severe challenges to wheat (Triticum aestivum L.) production worldwide. An investigation of the interaction between wheat and CCN can greatly improve our understanding of how nematodes alter wheat root metabolic pathways for their development and could contribute to new control strategies against CCN. In this study, we conducted transcriptome analyses of wheat cv. Wen 19 (Wen19) by using RNA-Seq during the compatible interaction with CCN at 1, 3 and 8 days past inoculation (dpi). In total, 71,569 transcripts were identified, and 10,929 of them were examined as differentially expressed genes (DEGs) in response to CCN infection. Based on the functional annotation and orthologous findings, the protein phosphorylation, oxidation-reduction process, regulation of transcription, metabolic process, transport, and response process as well as many other pathways previously reported were enriched at the transcriptional level. Plant cell wall hydrolysis and modifying proteins, auxin biosynthesis, signalling and transporter genes were up-regulated by CCN infection to facilitate penetration, migration and syncytium establishment. Genes responding to wounding and jasmonic acid stimuli were enriched at 1 dpi. We found 16 NBS-LRR genes, 12 of which were down-regulated, indicating the repression of resistance. The expression of genes encoding antioxidant enzymes, glutathione S-transferases and UDP-glucosyltransferase was significantly up-regulated during CCN infection, indicating that they may play key roles in the compatible interaction of wheat with CCN. Taken together, the results obtained from the transcriptome analyses indicate that the genes involved in oxidation-reduction processes, induction and suppression of resistance, metabolism, transport and syncytium establishment may be involved in the compatible interaction of Wen 19 with CCN. This study provides new insights into the responses of wheat to CCN infection. These insights could facilitate the elucidation of the potential mechanisms of wheat responses to CCN.
    36 schema:genre article
    37 schema:inLanguage en
    38 schema:isAccessibleForFree true
    39 schema:isPartOf N26b9b4c19ba842c28b05a33710d0333e
    40 N78b6d297344248b9a50d526af2c235aa
    41 sg:journal.1045337
    42 schema:keywords CCN
    43 CCN infection
    44 Heterodera avenae
    45 NBS-LRR genes
    46 RNA-seq
    47 UDP-glucosyltransferase
    48 Wen 19
    49 acid stimuli
    50 analysis
    51 annotation
    52 antioxidant enzymes
    53 auxin biosynthesis
    54 avenae
    55 biosynthesis
    56 cell wall hydrolysis
    57 cereal cyst nematode
    58 cereal cyst nematode Heterodera avenae
    59 challenges
    60 compatible interaction
    61 control strategy
    62 cv
    63 cyst nematode
    64 cyst nematode Heterodera avenae
    65 days
    66 development
    67 dpi
    68 elucidation
    69 enzyme
    70 establishment
    71 expression
    72 expression of genes
    73 findings
    74 functional annotation
    75 genes
    76 glutathione S
    77 hydrolysis
    78 induction
    79 infection
    80 inoculation
    81 insights
    82 interaction
    83 investigation
    84 jasmonic acid stimulus
    85 key role
    86 levels
    87 mechanism
    88 metabolic pathways
    89 metabolic processes
    90 metabolism
    91 migration
    92 nematode Heterodera avenae
    93 nematodes
    94 new control strategy
    95 new insights
    96 orthologous findings
    97 oxidation-reduction process
    98 pathway
    99 penetration
    100 phosphorylation
    101 plant cell wall hydrolysis
    102 potential mechanisms
    103 process
    104 production
    105 profiling
    106 protein
    107 protein phosphorylation
    108 regulation
    109 regulation of transcription
    110 repression
    111 repression of resistance
    112 resistance
    113 response
    114 response of wheat
    115 response process
    116 results
    117 role
    118 root metabolic pathways
    119 severe challenges
    120 signaling
    121 stimuli
    122 strategies
    123 study
    124 suppression
    125 suppression of resistance
    126 syncytium establishment
    127 total
    128 transcription
    129 transcriptional level
    130 transcriptional profiling
    131 transcriptome analysis
    132 transcripts
    133 transferase
    134 transport
    135 transporter gene
    136 understanding
    137 wall hydrolysis
    138 wheat
    139 wheat cv
    140 wheat response
    141 wheat root metabolic pathways
    142 wounding
    143 schema:name Transcriptional profiling of wheat (Triticum aestivum L.) during a compatible interaction with the cereal cyst nematode Heterodera avenae
    144 schema:pagination 2184
    145 schema:productId N83b662117fd743c1a9bee51982b3de86
    146 Nb890a39860af44b99f583b537f78018c
    147 Ne759b14d17194c0ea8a493c26e21fc38
    148 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112201159
    149 https://doi.org/10.1038/s41598-018-37824-9
    150 schema:sdDatePublished 2022-01-01T18:53
    151 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    152 schema:sdPublisher Ne83a8e73c25a40c6bafe3343b655afef
    153 schema:url https://doi.org/10.1038/s41598-018-37824-9
    154 sgo:license sg:explorer/license/
    155 sgo:sdDataset articles
    156 rdf:type schema:ScholarlyArticle
    157 N02ef53e5945e4915a61e4c8d542e71a6 rdf:first sg:person.01234620657.87
    158 rdf:rest Nde8e21fd1f5f4b90a9e479d03be1de07
    159 N0a03ae9d54694650b608c2a304d5e692 rdf:first sg:person.0602256473.30
    160 rdf:rest Ne8bcd418a85e4d54a6aae0c21af2a8c6
    161 N0b843bad357e4497ba2473fb54e0adad rdf:first sg:person.0643014415.89
    162 rdf:rest Nd28e3719d3ba4c3f8cc87b0b1e135ee5
    163 N1910c8ed38e944ff8ff2559431231fdf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    164 schema:name Tylenchoidea
    165 rdf:type schema:DefinedTerm
    166 N1e307fd93e474adba5d921d349806466 rdf:first sg:person.0716505073.40
    167 rdf:rest N0b843bad357e4497ba2473fb54e0adad
    168 N26b9b4c19ba842c28b05a33710d0333e schema:issueNumber 1
    169 rdf:type schema:PublicationIssue
    170 N2e1589032fa944358444b06f2ed8f989 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    171 schema:name Plant Roots
    172 rdf:type schema:DefinedTerm
    173 N33785609e1aa42c6a7038898f9dbea46 rdf:first sg:person.01101046673.18
    174 rdf:rest rdf:nil
    175 N636522805cc24436b1f28e69efaef1d8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    176 schema:name Gene Expression Profiling
    177 rdf:type schema:DefinedTerm
    178 N6a18cbc251474e6a93df1b90210f2d76 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    179 schema:name Host-Parasite Interactions
    180 rdf:type schema:DefinedTerm
    181 N6b91473d02d449ffa0c267274f263c79 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    182 schema:name Plant Growth Regulators
    183 rdf:type schema:DefinedTerm
    184 N75be0181e61748c3b5cd0d65a6037717 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    185 schema:name Triticum
    186 rdf:type schema:DefinedTerm
    187 N78b6d297344248b9a50d526af2c235aa schema:volumeNumber 9
    188 rdf:type schema:PublicationVolume
    189 N83b662117fd743c1a9bee51982b3de86 schema:name doi
    190 schema:value 10.1038/s41598-018-37824-9
    191 rdf:type schema:PropertyValue
    192 N84fe06e51e1948039eae622ea0f82602 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    193 schema:name Animals
    194 rdf:type schema:DefinedTerm
    195 N90bcf125e2c24a038798d09c7afb2e4d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    196 schema:name Gene Expression Regulation, Plant
    197 rdf:type schema:DefinedTerm
    198 Na1dda6eb4a75481bb5c2bf8afd32836a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    199 schema:name Plant Diseases
    200 rdf:type schema:DefinedTerm
    201 Nb890a39860af44b99f583b537f78018c schema:name dimensions_id
    202 schema:value pub.1112201159
    203 rdf:type schema:PropertyValue
    204 Nd097ff31660d48d5835b026765682c1b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    205 schema:name Genes, Plant
    206 rdf:type schema:DefinedTerm
    207 Nd21f786fd9ab428eb7363e0edf9ac5fb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    208 schema:name Metabolic Networks and Pathways
    209 rdf:type schema:DefinedTerm
    210 Nd28e3719d3ba4c3f8cc87b0b1e135ee5 rdf:first sg:person.01141604615.18
    211 rdf:rest N02ef53e5945e4915a61e4c8d542e71a6
    212 Nd3cfe90c1fd94bf88de8d7e07393b0a3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    213 schema:name RNA-Seq
    214 rdf:type schema:DefinedTerm
    215 Nd8ccd7764f67472c894a04f0d124b7bb rdf:first sg:person.013134417135.36
    216 rdf:rest N0a03ae9d54694650b608c2a304d5e692
    217 Nde8e21fd1f5f4b90a9e479d03be1de07 rdf:first sg:person.01231301336.89
    218 rdf:rest N33785609e1aa42c6a7038898f9dbea46
    219 Ne6c9cbcba2b64307bfb5305da6106c31 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    220 schema:name Edible Grain
    221 rdf:type schema:DefinedTerm
    222 Ne759b14d17194c0ea8a493c26e21fc38 schema:name pubmed_id
    223 schema:value 30778126
    224 rdf:type schema:PropertyValue
    225 Ne83a8e73c25a40c6bafe3343b655afef schema:name Springer Nature - SN SciGraph project
    226 rdf:type schema:Organization
    227 Ne8bcd418a85e4d54a6aae0c21af2a8c6 rdf:first sg:person.01257547373.17
    228 rdf:rest N1e307fd93e474adba5d921d349806466
    229 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    230 schema:name Biological Sciences
    231 rdf:type schema:DefinedTerm
    232 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
    233 schema:name Biochemistry and Cell Biology
    234 rdf:type schema:DefinedTerm
    235 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
    236 schema:name Genetics
    237 rdf:type schema:DefinedTerm
    238 sg:grant.8191443 http://pending.schema.org/fundedItem sg:pub.10.1038/s41598-018-37824-9
    239 rdf:type schema:MonetaryGrant
    240 sg:journal.1045337 schema:issn 2045-2322
    241 schema:name Scientific Reports
    242 schema:publisher Springer Nature
    243 rdf:type schema:Periodical
    244 sg:person.01101046673.18 schema:affiliation grid-institutes:grid.464356.6
    245 schema:familyName Peng
    246 schema:givenName De-Liang
    247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101046673.18
    248 rdf:type schema:Person
    249 sg:person.01141604615.18 schema:affiliation grid-institutes:grid.464356.6
    250 schema:familyName Liu
    251 schema:givenName Shi-Ming
    252 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141604615.18
    253 rdf:type schema:Person
    254 sg:person.01231301336.89 schema:affiliation grid-institutes:grid.464356.6
    255 schema:familyName Qiu
    256 schema:givenName De-Wen
    257 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01231301336.89
    258 rdf:type schema:Person
    259 sg:person.01234620657.87 schema:affiliation grid-institutes:grid.454322.6
    260 schema:familyName Clarke
    261 schema:givenName Jihong Liu
    262 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01234620657.87
    263 rdf:type schema:Person
    264 sg:person.01257547373.17 schema:affiliation grid-institutes:grid.464356.6
    265 schema:familyName Peng
    266 schema:givenName Huan
    267 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257547373.17
    268 rdf:type schema:Person
    269 sg:person.013134417135.36 schema:affiliation grid-institutes:grid.464356.6
    270 schema:familyName Qiao
    271 schema:givenName Fen
    272 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013134417135.36
    273 rdf:type schema:Person
    274 sg:person.0602256473.30 schema:affiliation grid-institutes:grid.464356.6
    275 schema:familyName Kong
    276 schema:givenName Ling-An
    277 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602256473.30
    278 rdf:type schema:Person
    279 sg:person.0643014415.89 schema:affiliation grid-institutes:grid.464356.6
    280 schema:familyName Wu
    281 schema:givenName Du-Qing
    282 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0643014415.89
    283 rdf:type schema:Person
    284 sg:person.0716505073.40 schema:affiliation grid-institutes:grid.464356.6
    285 schema:familyName Huang
    286 schema:givenName Wen-Kun
    287 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0716505073.40
    288 rdf:type schema:Person
    289 sg:pub.10.1007/bf00225719 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026471846
    290 https://doi.org/10.1007/bf00225719
    291 rdf:type schema:CreativeWork
    292 sg:pub.10.1007/s00425-006-0270-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003825232
    293 https://doi.org/10.1007/s00425-006-0270-8
    294 rdf:type schema:CreativeWork
    295 sg:pub.10.1007/s00425-007-0578-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1021610920
    296 https://doi.org/10.1007/s00425-007-0578-z
    297 rdf:type schema:CreativeWork
    298 sg:pub.10.1007/s10658-011-9768-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028221524
    299 https://doi.org/10.1007/s10658-011-9768-4
    300 rdf:type schema:CreativeWork
    301 sg:pub.10.1007/s11101-017-9510-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085211067
    302 https://doi.org/10.1007/s11101-017-9510-8
    303 rdf:type schema:CreativeWork
    304 sg:pub.10.1038/nature11651 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046632196
    305 https://doi.org/10.1038/nature11651
    306 rdf:type schema:CreativeWork
    307 sg:pub.10.1038/nprot.2012.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030124536
    308 https://doi.org/10.1038/nprot.2012.016
    309 rdf:type schema:CreativeWork
    310 sg:pub.10.1038/nprot.2013.084 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051115056
    311 https://doi.org/10.1038/nprot.2013.084
    312 rdf:type schema:CreativeWork
    313 sg:pub.10.1038/s41598-017-00971-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085114463
    314 https://doi.org/10.1038/s41598-017-00971-6
    315 rdf:type schema:CreativeWork
    316 sg:pub.10.1038/s41598-017-09945-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091313414
    317 https://doi.org/10.1038/s41598-017-09945-0
    318 rdf:type schema:CreativeWork
    319 sg:pub.10.1038/s41598-017-14047-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1092446397
    320 https://doi.org/10.1038/s41598-017-14047-y
    321 rdf:type schema:CreativeWork
    322 sg:pub.10.1186/1471-2164-12-220 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019568148
    323 https://doi.org/10.1186/1471-2164-12-220
    324 rdf:type schema:CreativeWork
    325 sg:pub.10.1186/1471-2164-13-133 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051919581
    326 https://doi.org/10.1186/1471-2164-13-133
    327 rdf:type schema:CreativeWork
    328 sg:pub.10.1186/s12864-015-1316-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011509578
    329 https://doi.org/10.1186/s12864-015-1316-8
    330 rdf:type schema:CreativeWork
    331 sg:pub.10.1186/s12864-015-2037-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051848897
    332 https://doi.org/10.1186/s12864-015-2037-8
    333 rdf:type schema:CreativeWork
    334 grid-institutes:grid.454322.6 schema:alternateName NIBIO - Norwegian Institute of Bioeconomy Research, P.O. Box 115, N-1431 Oslo, Ås Norway
    335 schema:name NIBIO - Norwegian Institute of Bioeconomy Research, P.O. Box 115, N-1431 Oslo, Ås Norway
    336 rdf:type schema:Organization
    337 grid-institutes:grid.464356.6 schema:alternateName State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China
    338 schema:name State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193 China
    339 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...