Human serum albumin alters specific genes that can play a role in survival and persistence in Acinetobacter baumannii View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-12

AUTHORS

Brettni Quinn, Nyah Rodman, Eugenio Jara, Jennifer S. Fernandez, Jasmine Martinez, German M. Traglia, Sabrina Montaña, Virginia Cantera, Kori Place, Robert A. Bonomo, Andres Iriarte, María Soledad Ramírez

ABSTRACT

In the past few decades Acinetobacter baumannii has emerged as a notorious nosocomial pathogen because of its ability to acquire genetic material and persist in extreme environments. Recently, human serum albumin (HSA) was shown to significantly increase natural transformation frequency in A. baumannii. This observation led us to perform transcriptomic analysis of strain A118 under HSA induction to identify genes that are altered by HSA. Our results revealed the statistically significant differential expression of 296 protein-coding genes, including those associated with motility, biofilm formation, metabolism, efflux pumps, capsule synthesis, and transcriptional regulation. Phenotypic analysis of these traits showed an increase in surface-associated motility, a decrease in biofilm formation, reduced activity of a citric acid cycle associated enzyme, and increased survival associated with zinc availability. Furthermore, the expression of genes known to play a role in pathogenicity and antibiotic resistance were altered. These genes included those associated with RND-type efflux pumps, the type VI secretion system, iron acquisition/metabolism, and ß-lactam resistance. Together, these results illustrate how human products, in particular HSA, may play a significant role in both survival and persistence of A. baumannii. More... »

PAGES

14741

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41598-018-33072-z

DOI

http://dx.doi.org/10.1038/s41598-018-33072-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1107275460

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30282985


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "California State University, Fullerton", 
          "id": "https://www.grid.ac/institutes/grid.253559.d", 
          "name": [
            "Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Quinn", 
        "givenName": "Brettni", 
        "id": "sg:person.012616534351.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012616534351.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "California State University, Fullerton", 
          "id": "https://www.grid.ac/institutes/grid.253559.d", 
          "name": [
            "Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rodman", 
        "givenName": "Nyah", 
        "id": "sg:person.010212675234.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010212675234.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of the Republic", 
          "id": "https://www.grid.ac/institutes/grid.11630.35", 
          "name": [
            "\u00c1rea Gen\u00e9tica, Facultad de Veterinaria, Universidad de la Rep\u00fablica, Montevideo, Uruguay"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jara", 
        "givenName": "Eugenio", 
        "id": "sg:person.010530034625.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010530034625.60"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "California State University, Fullerton", 
          "id": "https://www.grid.ac/institutes/grid.253559.d", 
          "name": [
            "Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fernandez", 
        "givenName": "Jennifer S.", 
        "id": "sg:person.011723465566.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011723465566.83"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "California State University, Fullerton", 
          "id": "https://www.grid.ac/institutes/grid.253559.d", 
          "name": [
            "Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Martinez", 
        "givenName": "Jasmine", 
        "id": "sg:person.014270234414.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014270234414.84"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital de Cl\u00ednicas \"Jos\u00e9 de San Mart\u00edn\"", 
          "id": "https://www.grid.ac/institutes/grid.412714.5", 
          "name": [
            "Laboratorio de Bacteriolog\u00eda Cl\u00ednica, Departamento de Bioqu\u00edmica Cl\u00ednica, Hospital de Cl\u00ednicas Jos\u00e9 de San Mart\u00edn, Facultad de Farmacia y Bioqu\u00edmica, Buenos Aires, Argentina"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Traglia", 
        "givenName": "German M.", 
        "id": "sg:person.0642772524.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642772524.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Buenos Aires", 
          "id": "https://www.grid.ac/institutes/grid.7345.5", 
          "name": [
            "Instituto de Microbiolog\u00eda y Parasitolog\u00eda M\u00e9dica (IMPaM, UBA-CONICET), Facultad de Medicina, Universidad de Buenos, Aires, Argentina"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Monta\u00f1a", 
        "givenName": "Sabrina", 
        "id": "sg:person.0575762534.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0575762534.76"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of the Republic", 
          "id": "https://www.grid.ac/institutes/grid.11630.35", 
          "name": [
            "Laboratorio de Biolog\u00eda Computacional, Dpto. de Desarrollo Biotecnol\u00f3gico, Instituto de Higiene, Facultad de Medicina, UdelaR, Montevideo, Uruguay"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cantera", 
        "givenName": "Virginia", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "California State University, Fullerton", 
          "id": "https://www.grid.ac/institutes/grid.253559.d", 
          "name": [
            "Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Place", 
        "givenName": "Kori", 
        "id": "sg:person.010727520002.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010727520002.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Case Western Reserve University", 
          "id": "https://www.grid.ac/institutes/grid.67105.35", 
          "name": [
            "Medical Service and GRECC, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA", 
            "Departments of Medicine, Pharmacology, Molecular Biology and Microbiology, Biochemistry, Proteomics and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA", 
            "CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (Case VA CARES), Cleveland, Ohio, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bonomo", 
        "givenName": "Robert A.", 
        "id": "sg:person.01215450065.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01215450065.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of the Republic", 
          "id": "https://www.grid.ac/institutes/grid.11630.35", 
          "name": [
            "Laboratorio de Biolog\u00eda Computacional, Dpto. de Desarrollo Biotecnol\u00f3gico, Instituto de Higiene, Facultad de Medicina, UdelaR, Montevideo, Uruguay"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Iriarte", 
        "givenName": "Andres", 
        "id": "sg:person.01244540272.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01244540272.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "California State University, Fullerton", 
          "id": "https://www.grid.ac/institutes/grid.253559.d", 
          "name": [
            "Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ram\u00edrez", 
        "givenName": "Mar\u00eda Soledad", 
        "id": "sg:person.0661257075.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0661257075.43"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.3390/genes8010012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002514642"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/iai.00366-10", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004088815"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mbio.00309-15", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004102631"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/msphere.00013-15", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005015390"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gad.1510307", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005401912"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.resmic.2013.03.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006437165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pgen.0020007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006455749"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mbio.00360-13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007042622"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.chom.2013.11.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007481384"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/cmr.00058-07", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008741242"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0059388", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009016227"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.ppat.1003068", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009574397"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0022674", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009708715"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aem.05316-11", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010202239"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jb.00167-06", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012471489"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jb.186.13.4387-4389.2004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012477092"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mbio.00430-16", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014916968"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0062160", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014932338"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13059-014-0550-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015222646", 
          "https://doi.org/10.1186/s13059-014-0550-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13059-014-0550-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015222646", 
          "https://doi.org/10.1186/s13059-014-0550-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1574-6976.2012.00344.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015857720"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/btt656", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016247401"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/genes8010019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016595793"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s1399004714008311", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017033905"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jb.00481-08", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017902417"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1752-0509-6-s1-s20", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017985777", 
          "https://doi.org/10.1186/1752-0509-6-s1-s20"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m110.148171", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018233324"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1523116113", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018305873"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/mmi.12307", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019109948"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.febslet.2007.10.063", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020218863"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jb.00917-10", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020362285"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1574-6968.2002.tb11363.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020975019"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1574-6968.2002.tb11363.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020975019"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/iai.00065-13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021718789"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mbio.00697-16", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021847100"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.02556-12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022280239"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/infdis/jiu024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022927052"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/gbe/evu176", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027076353"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.00756-12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028024390"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1099/mic.0.26541-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030590733"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12275-009-0158-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031107302", 
          "https://doi.org/10.1007/s12275-009-0158-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12275-009-0158-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031107302", 
          "https://doi.org/10.1007/s12275-009-0158-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/gbe/evu225", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032179423"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncomms10261", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034790210", 
          "https://doi.org/10.1038/ncomms10261"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/505599", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035449798"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-006-0554-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036673723", 
          "https://doi.org/10.1007/s00253-006-0554-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-006-0554-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036673723", 
          "https://doi.org/10.1007/s00253-006-0554-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5808/gi.2015.13.1.2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040354657"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jb.00188-15", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041838767"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c5mt00170f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042892813"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/iai.00540-13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043749916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/iai.00096-09", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045615176"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1502966112", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046012191"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jb.00754-13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047719279"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.271.43.26609", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048409142"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jb.00428-08", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050111240"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3389/fmicb.2012.00148", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051195248"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1752-0509-6-s1-s13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051647352", 
          "https://doi.org/10.1186/1752-0509-6-s1-s13"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0378-1097(02)00879-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054654908"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m115.700518", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058214288"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/infdis/jiw529", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059710471"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1099/mgen.0.000102", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060393912"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1099/mic.0.2008/019471-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060396455"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.00529-16", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062708996"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/ecosalplus.3.4.5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062713864"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/microbiolspec.vmbf-0026-2015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062731436"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074519359", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4049/jimmunol.0902663", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078132488"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083113238", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083302984", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jb.00011-17", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084221917"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0174454", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084307203"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/iai.00198-17", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084779800"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/21505594.2017.1323164", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085286187"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0182139", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090992945"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0190599", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100259195"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00284-017-1417-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100394373", 
          "https://doi.org/10.1007/s00284-017-1417-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0192288", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100801319"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/s41598-018-21841-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101113742", 
          "https://doi.org/10.1038/s41598-018-21841-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/s41598-018-21841-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101113742", 
          "https://doi.org/10.1038/s41598-018-21841-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/s41598-018-21841-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101113742", 
          "https://doi.org/10.1038/s41598-018-21841-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/s41564-018-0151-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103565821", 
          "https://doi.org/10.1038/s41564-018-0151-5"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-12", 
    "datePublishedReg": "2018-12-01", 
    "description": "In the past few decades Acinetobacter baumannii has emerged as a notorious nosocomial pathogen because of its ability to acquire genetic material and persist in extreme environments. Recently, human serum albumin (HSA) was shown to significantly increase natural transformation frequency in A. baumannii. This observation led us to perform transcriptomic analysis of strain A118 under HSA induction to identify genes that are altered by HSA. Our results revealed the statistically significant differential expression of 296 protein-coding genes, including those associated with motility, biofilm formation, metabolism, efflux pumps, capsule synthesis, and transcriptional regulation. Phenotypic analysis of these traits showed an increase in surface-associated motility, a decrease in biofilm formation, reduced activity of a citric acid cycle associated enzyme, and increased survival associated with zinc availability. Furthermore, the expression of genes known to play a role in pathogenicity and antibiotic resistance were altered. These genes included those associated with RND-type efflux pumps, the type VI secretion system, iron acquisition/metabolism, and \u00df-lactam resistance. Together, these results illustrate how human products, in particular HSA, may play a significant role in both survival and persistence of A. baumannii.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/s41598-018-33072-z", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2457024", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2686449", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2459639", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.4103914", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.7439763", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2401819", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2457788", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1045337", 
        "issn": [
          "2045-2322"
        ], 
        "name": "Scientific Reports", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "8"
      }
    ], 
    "name": "Human serum albumin alters specific genes that can play a role in survival and persistence in Acinetobacter baumannii", 
    "pagination": "14741", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "7efe536d0abdb70b1e93fe08d401a8ca7c1384b5cbca77be9ba03b8b0d145bc9"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30282985"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101563288"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s41598-018-33072-z"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1107275460"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s41598-018-33072-z", 
      "https://app.dimensions.ai/details/publication/pub.1107275460"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T18:27", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8675_00000555.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/s41598-018-33072-z"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-33072-z'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-33072-z'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-33072-z'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-33072-z'


 

This table displays all metadata directly associated to this object as RDF triples.

407 TRIPLES      21 PREDICATES      105 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s41598-018-33072-z schema:about anzsrc-for:06
2 anzsrc-for:0604
3 schema:author Nc7d616ab459b4195b7f1d5214bdd3495
4 schema:citation sg:pub.10.1007/s00253-006-0554-8
5 sg:pub.10.1007/s00284-017-1417-5
6 sg:pub.10.1007/s12275-009-0158-y
7 sg:pub.10.1038/ncomms10261
8 sg:pub.10.1038/s41564-018-0151-5
9 sg:pub.10.1038/s41598-018-21841-9
10 sg:pub.10.1186/1752-0509-6-s1-s13
11 sg:pub.10.1186/1752-0509-6-s1-s20
12 sg:pub.10.1186/s13059-014-0550-8
13 https://app.dimensions.ai/details/publication/pub.1074519359
14 https://app.dimensions.ai/details/publication/pub.1083113238
15 https://app.dimensions.ai/details/publication/pub.1083302984
16 https://doi.org/10.1016/j.chom.2013.11.008
17 https://doi.org/10.1016/j.febslet.2007.10.063
18 https://doi.org/10.1016/j.resmic.2013.03.017
19 https://doi.org/10.1016/s0378-1097(02)00879-0
20 https://doi.org/10.1039/c5mt00170f
21 https://doi.org/10.1073/pnas.1502966112
22 https://doi.org/10.1073/pnas.1523116113
23 https://doi.org/10.1074/jbc.271.43.26609
24 https://doi.org/10.1074/jbc.m110.148171
25 https://doi.org/10.1074/jbc.m115.700518
26 https://doi.org/10.1080/21505594.2017.1323164
27 https://doi.org/10.1086/505599
28 https://doi.org/10.1093/bioinformatics/btt656
29 https://doi.org/10.1093/gbe/evu176
30 https://doi.org/10.1093/gbe/evu225
31 https://doi.org/10.1093/infdis/jiu024
32 https://doi.org/10.1093/infdis/jiw529
33 https://doi.org/10.1099/mgen.0.000102
34 https://doi.org/10.1099/mic.0.2008/019471-0
35 https://doi.org/10.1099/mic.0.26541-0
36 https://doi.org/10.1101/gad.1510307
37 https://doi.org/10.1107/s1399004714008311
38 https://doi.org/10.1111/j.1574-6968.2002.tb11363.x
39 https://doi.org/10.1111/j.1574-6976.2012.00344.x
40 https://doi.org/10.1111/mmi.12307
41 https://doi.org/10.1128/aac.00529-16
42 https://doi.org/10.1128/aac.00756-12
43 https://doi.org/10.1128/aac.02556-12
44 https://doi.org/10.1128/aem.05316-11
45 https://doi.org/10.1128/cmr.00058-07
46 https://doi.org/10.1128/ecosalplus.3.4.5
47 https://doi.org/10.1128/iai.00065-13
48 https://doi.org/10.1128/iai.00096-09
49 https://doi.org/10.1128/iai.00198-17
50 https://doi.org/10.1128/iai.00366-10
51 https://doi.org/10.1128/iai.00540-13
52 https://doi.org/10.1128/jb.00011-17
53 https://doi.org/10.1128/jb.00167-06
54 https://doi.org/10.1128/jb.00188-15
55 https://doi.org/10.1128/jb.00428-08
56 https://doi.org/10.1128/jb.00481-08
57 https://doi.org/10.1128/jb.00754-13
58 https://doi.org/10.1128/jb.00917-10
59 https://doi.org/10.1128/jb.186.13.4387-4389.2004
60 https://doi.org/10.1128/mbio.00309-15
61 https://doi.org/10.1128/mbio.00360-13
62 https://doi.org/10.1128/mbio.00430-16
63 https://doi.org/10.1128/mbio.00697-16
64 https://doi.org/10.1128/microbiolspec.vmbf-0026-2015
65 https://doi.org/10.1128/msphere.00013-15
66 https://doi.org/10.1371/journal.pgen.0020007
67 https://doi.org/10.1371/journal.pone.0022674
68 https://doi.org/10.1371/journal.pone.0059388
69 https://doi.org/10.1371/journal.pone.0062160
70 https://doi.org/10.1371/journal.pone.0174454
71 https://doi.org/10.1371/journal.pone.0182139
72 https://doi.org/10.1371/journal.pone.0190599
73 https://doi.org/10.1371/journal.pone.0192288
74 https://doi.org/10.1371/journal.ppat.1003068
75 https://doi.org/10.3389/fmicb.2012.00148
76 https://doi.org/10.3390/genes8010012
77 https://doi.org/10.3390/genes8010019
78 https://doi.org/10.4049/jimmunol.0902663
79 https://doi.org/10.5808/gi.2015.13.1.2
80 schema:datePublished 2018-12
81 schema:datePublishedReg 2018-12-01
82 schema:description In the past few decades Acinetobacter baumannii has emerged as a notorious nosocomial pathogen because of its ability to acquire genetic material and persist in extreme environments. Recently, human serum albumin (HSA) was shown to significantly increase natural transformation frequency in A. baumannii. This observation led us to perform transcriptomic analysis of strain A118 under HSA induction to identify genes that are altered by HSA. Our results revealed the statistically significant differential expression of 296 protein-coding genes, including those associated with motility, biofilm formation, metabolism, efflux pumps, capsule synthesis, and transcriptional regulation. Phenotypic analysis of these traits showed an increase in surface-associated motility, a decrease in biofilm formation, reduced activity of a citric acid cycle associated enzyme, and increased survival associated with zinc availability. Furthermore, the expression of genes known to play a role in pathogenicity and antibiotic resistance were altered. These genes included those associated with RND-type efflux pumps, the type VI secretion system, iron acquisition/metabolism, and ß-lactam resistance. Together, these results illustrate how human products, in particular HSA, may play a significant role in both survival and persistence of A. baumannii.
83 schema:genre research_article
84 schema:inLanguage en
85 schema:isAccessibleForFree true
86 schema:isPartOf N0baefd90752e4c7997dde1323cd52a2c
87 N0faaab45ca53434c980eeda915a8abbe
88 sg:journal.1045337
89 schema:name Human serum albumin alters specific genes that can play a role in survival and persistence in Acinetobacter baumannii
90 schema:pagination 14741
91 schema:productId N105e5472889a485c88075da402f381f7
92 N4b0b0c74a4164f0b8d944e604dfed892
93 N6e49aca667ce485c80c42bcda78c2ac8
94 N9fab551737844e7f9e6544e3db4f2466
95 Ndbabd9ec7c334a4dbf57d3afbd8d9ca0
96 schema:sameAs https://app.dimensions.ai/details/publication/pub.1107275460
97 https://doi.org/10.1038/s41598-018-33072-z
98 schema:sdDatePublished 2019-04-10T18:27
99 schema:sdLicense https://scigraph.springernature.com/explorer/license/
100 schema:sdPublisher N7f052feebf744c858d94359e918aae88
101 schema:url https://www.nature.com/articles/s41598-018-33072-z
102 sgo:license sg:explorer/license/
103 sgo:sdDataset articles
104 rdf:type schema:ScholarlyArticle
105 N0baefd90752e4c7997dde1323cd52a2c schema:issueNumber 1
106 rdf:type schema:PublicationIssue
107 N0fa283782173475d8be28582fc9529dd rdf:first sg:person.0661257075.43
108 rdf:rest rdf:nil
109 N0faaab45ca53434c980eeda915a8abbe schema:volumeNumber 8
110 rdf:type schema:PublicationVolume
111 N105e5472889a485c88075da402f381f7 schema:name doi
112 schema:value 10.1038/s41598-018-33072-z
113 rdf:type schema:PropertyValue
114 N19e79f6987f94f06bb4b583d764aac5d rdf:first sg:person.014270234414.84
115 rdf:rest Nea343f6a718c451db98dfbec5d197fa4
116 N3dbfc267b9e7438b91d991c1eb7929f9 rdf:first sg:person.011723465566.83
117 rdf:rest N19e79f6987f94f06bb4b583d764aac5d
118 N4b0b0c74a4164f0b8d944e604dfed892 schema:name dimensions_id
119 schema:value pub.1107275460
120 rdf:type schema:PropertyValue
121 N4df591c775a7459da018bbefed73fb88 rdf:first sg:person.01244540272.35
122 rdf:rest N0fa283782173475d8be28582fc9529dd
123 N4df9d3a957114711aea1e8067d657c67 rdf:first sg:person.010727520002.27
124 rdf:rest N7137762595d94f5695dbe47576273da5
125 N6e49aca667ce485c80c42bcda78c2ac8 schema:name nlm_unique_id
126 schema:value 101563288
127 rdf:type schema:PropertyValue
128 N7137762595d94f5695dbe47576273da5 rdf:first sg:person.01215450065.94
129 rdf:rest N4df591c775a7459da018bbefed73fb88
130 N76a1b4bdd2fe4541ae5d6981990cbca1 rdf:first sg:person.010212675234.63
131 rdf:rest Nd04a3ae9764e432e9e526066448519c1
132 N7f052feebf744c858d94359e918aae88 schema:name Springer Nature - SN SciGraph project
133 rdf:type schema:Organization
134 N9fab551737844e7f9e6544e3db4f2466 schema:name pubmed_id
135 schema:value 30282985
136 rdf:type schema:PropertyValue
137 Nc3d60df134614863b5f31eaa70bfff92 rdf:first Ne7a258de7c2a4a83a2e8d6bf00d4cc05
138 rdf:rest N4df9d3a957114711aea1e8067d657c67
139 Nc7d616ab459b4195b7f1d5214bdd3495 rdf:first sg:person.012616534351.86
140 rdf:rest N76a1b4bdd2fe4541ae5d6981990cbca1
141 Nd04a3ae9764e432e9e526066448519c1 rdf:first sg:person.010530034625.60
142 rdf:rest N3dbfc267b9e7438b91d991c1eb7929f9
143 Nd5128f881c8b44ceb4a8a82514b653c1 rdf:first sg:person.0575762534.76
144 rdf:rest Nc3d60df134614863b5f31eaa70bfff92
145 Ndbabd9ec7c334a4dbf57d3afbd8d9ca0 schema:name readcube_id
146 schema:value 7efe536d0abdb70b1e93fe08d401a8ca7c1384b5cbca77be9ba03b8b0d145bc9
147 rdf:type schema:PropertyValue
148 Ne7a258de7c2a4a83a2e8d6bf00d4cc05 schema:affiliation https://www.grid.ac/institutes/grid.11630.35
149 schema:familyName Cantera
150 schema:givenName Virginia
151 rdf:type schema:Person
152 Nea343f6a718c451db98dfbec5d197fa4 rdf:first sg:person.0642772524.17
153 rdf:rest Nd5128f881c8b44ceb4a8a82514b653c1
154 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
155 schema:name Biological Sciences
156 rdf:type schema:DefinedTerm
157 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
158 schema:name Genetics
159 rdf:type schema:DefinedTerm
160 sg:grant.2401819 http://pending.schema.org/fundedItem sg:pub.10.1038/s41598-018-33072-z
161 rdf:type schema:MonetaryGrant
162 sg:grant.2457024 http://pending.schema.org/fundedItem sg:pub.10.1038/s41598-018-33072-z
163 rdf:type schema:MonetaryGrant
164 sg:grant.2457788 http://pending.schema.org/fundedItem sg:pub.10.1038/s41598-018-33072-z
165 rdf:type schema:MonetaryGrant
166 sg:grant.2459639 http://pending.schema.org/fundedItem sg:pub.10.1038/s41598-018-33072-z
167 rdf:type schema:MonetaryGrant
168 sg:grant.2686449 http://pending.schema.org/fundedItem sg:pub.10.1038/s41598-018-33072-z
169 rdf:type schema:MonetaryGrant
170 sg:grant.4103914 http://pending.schema.org/fundedItem sg:pub.10.1038/s41598-018-33072-z
171 rdf:type schema:MonetaryGrant
172 sg:grant.7439763 http://pending.schema.org/fundedItem sg:pub.10.1038/s41598-018-33072-z
173 rdf:type schema:MonetaryGrant
174 sg:journal.1045337 schema:issn 2045-2322
175 schema:name Scientific Reports
176 rdf:type schema:Periodical
177 sg:person.010212675234.63 schema:affiliation https://www.grid.ac/institutes/grid.253559.d
178 schema:familyName Rodman
179 schema:givenName Nyah
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010212675234.63
181 rdf:type schema:Person
182 sg:person.010530034625.60 schema:affiliation https://www.grid.ac/institutes/grid.11630.35
183 schema:familyName Jara
184 schema:givenName Eugenio
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010530034625.60
186 rdf:type schema:Person
187 sg:person.010727520002.27 schema:affiliation https://www.grid.ac/institutes/grid.253559.d
188 schema:familyName Place
189 schema:givenName Kori
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010727520002.27
191 rdf:type schema:Person
192 sg:person.011723465566.83 schema:affiliation https://www.grid.ac/institutes/grid.253559.d
193 schema:familyName Fernandez
194 schema:givenName Jennifer S.
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011723465566.83
196 rdf:type schema:Person
197 sg:person.01215450065.94 schema:affiliation https://www.grid.ac/institutes/grid.67105.35
198 schema:familyName Bonomo
199 schema:givenName Robert A.
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01215450065.94
201 rdf:type schema:Person
202 sg:person.01244540272.35 schema:affiliation https://www.grid.ac/institutes/grid.11630.35
203 schema:familyName Iriarte
204 schema:givenName Andres
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01244540272.35
206 rdf:type schema:Person
207 sg:person.012616534351.86 schema:affiliation https://www.grid.ac/institutes/grid.253559.d
208 schema:familyName Quinn
209 schema:givenName Brettni
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012616534351.86
211 rdf:type schema:Person
212 sg:person.014270234414.84 schema:affiliation https://www.grid.ac/institutes/grid.253559.d
213 schema:familyName Martinez
214 schema:givenName Jasmine
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014270234414.84
216 rdf:type schema:Person
217 sg:person.0575762534.76 schema:affiliation https://www.grid.ac/institutes/grid.7345.5
218 schema:familyName Montaña
219 schema:givenName Sabrina
220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0575762534.76
221 rdf:type schema:Person
222 sg:person.0642772524.17 schema:affiliation https://www.grid.ac/institutes/grid.412714.5
223 schema:familyName Traglia
224 schema:givenName German M.
225 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642772524.17
226 rdf:type schema:Person
227 sg:person.0661257075.43 schema:affiliation https://www.grid.ac/institutes/grid.253559.d
228 schema:familyName Ramírez
229 schema:givenName María Soledad
230 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0661257075.43
231 rdf:type schema:Person
232 sg:pub.10.1007/s00253-006-0554-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036673723
233 https://doi.org/10.1007/s00253-006-0554-8
234 rdf:type schema:CreativeWork
235 sg:pub.10.1007/s00284-017-1417-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100394373
236 https://doi.org/10.1007/s00284-017-1417-5
237 rdf:type schema:CreativeWork
238 sg:pub.10.1007/s12275-009-0158-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1031107302
239 https://doi.org/10.1007/s12275-009-0158-y
240 rdf:type schema:CreativeWork
241 sg:pub.10.1038/ncomms10261 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034790210
242 https://doi.org/10.1038/ncomms10261
243 rdf:type schema:CreativeWork
244 sg:pub.10.1038/s41564-018-0151-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103565821
245 https://doi.org/10.1038/s41564-018-0151-5
246 rdf:type schema:CreativeWork
247 sg:pub.10.1038/s41598-018-21841-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101113742
248 https://doi.org/10.1038/s41598-018-21841-9
249 rdf:type schema:CreativeWork
250 sg:pub.10.1186/1752-0509-6-s1-s13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051647352
251 https://doi.org/10.1186/1752-0509-6-s1-s13
252 rdf:type schema:CreativeWork
253 sg:pub.10.1186/1752-0509-6-s1-s20 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017985777
254 https://doi.org/10.1186/1752-0509-6-s1-s20
255 rdf:type schema:CreativeWork
256 sg:pub.10.1186/s13059-014-0550-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015222646
257 https://doi.org/10.1186/s13059-014-0550-8
258 rdf:type schema:CreativeWork
259 https://app.dimensions.ai/details/publication/pub.1074519359 schema:CreativeWork
260 https://app.dimensions.ai/details/publication/pub.1083113238 schema:CreativeWork
261 https://app.dimensions.ai/details/publication/pub.1083302984 schema:CreativeWork
262 https://doi.org/10.1016/j.chom.2013.11.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007481384
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1016/j.febslet.2007.10.063 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020218863
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1016/j.resmic.2013.03.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006437165
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1016/s0378-1097(02)00879-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054654908
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1039/c5mt00170f schema:sameAs https://app.dimensions.ai/details/publication/pub.1042892813
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1073/pnas.1502966112 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046012191
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1073/pnas.1523116113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018305873
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1074/jbc.271.43.26609 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048409142
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1074/jbc.m110.148171 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018233324
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1074/jbc.m115.700518 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058214288
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1080/21505594.2017.1323164 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085286187
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1086/505599 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035449798
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1093/bioinformatics/btt656 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016247401
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1093/gbe/evu176 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027076353
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1093/gbe/evu225 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032179423
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1093/infdis/jiu024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022927052
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1093/infdis/jiw529 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059710471
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1099/mgen.0.000102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060393912
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1099/mic.0.2008/019471-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060396455
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1099/mic.0.26541-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030590733
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1101/gad.1510307 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005401912
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1107/s1399004714008311 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017033905
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1111/j.1574-6968.2002.tb11363.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1020975019
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1111/j.1574-6976.2012.00344.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1015857720
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1111/mmi.12307 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019109948
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1128/aac.00529-16 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062708996
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1128/aac.00756-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028024390
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1128/aac.02556-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022280239
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1128/aem.05316-11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010202239
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1128/cmr.00058-07 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008741242
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1128/ecosalplus.3.4.5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062713864
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1128/iai.00065-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021718789
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1128/iai.00096-09 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045615176
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1128/iai.00198-17 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084779800
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1128/iai.00366-10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004088815
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1128/iai.00540-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043749916
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1128/jb.00011-17 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084221917
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1128/jb.00167-06 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012471489
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1128/jb.00188-15 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041838767
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1128/jb.00428-08 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050111240
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1128/jb.00481-08 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017902417
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1128/jb.00754-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047719279
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1128/jb.00917-10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020362285
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1128/jb.186.13.4387-4389.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012477092
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1128/mbio.00309-15 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004102631
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1128/mbio.00360-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007042622
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1128/mbio.00430-16 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014916968
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1128/mbio.00697-16 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021847100
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1128/microbiolspec.vmbf-0026-2015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062731436
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1128/msphere.00013-15 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005015390
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1371/journal.pgen.0020007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006455749
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1371/journal.pone.0022674 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009708715
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1371/journal.pone.0059388 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009016227
367 rdf:type schema:CreativeWork
368 https://doi.org/10.1371/journal.pone.0062160 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014932338
369 rdf:type schema:CreativeWork
370 https://doi.org/10.1371/journal.pone.0174454 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084307203
371 rdf:type schema:CreativeWork
372 https://doi.org/10.1371/journal.pone.0182139 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090992945
373 rdf:type schema:CreativeWork
374 https://doi.org/10.1371/journal.pone.0190599 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100259195
375 rdf:type schema:CreativeWork
376 https://doi.org/10.1371/journal.pone.0192288 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100801319
377 rdf:type schema:CreativeWork
378 https://doi.org/10.1371/journal.ppat.1003068 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009574397
379 rdf:type schema:CreativeWork
380 https://doi.org/10.3389/fmicb.2012.00148 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051195248
381 rdf:type schema:CreativeWork
382 https://doi.org/10.3390/genes8010012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002514642
383 rdf:type schema:CreativeWork
384 https://doi.org/10.3390/genes8010019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016595793
385 rdf:type schema:CreativeWork
386 https://doi.org/10.4049/jimmunol.0902663 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078132488
387 rdf:type schema:CreativeWork
388 https://doi.org/10.5808/gi.2015.13.1.2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040354657
389 rdf:type schema:CreativeWork
390 https://www.grid.ac/institutes/grid.11630.35 schema:alternateName University of the Republic
391 schema:name Laboratorio de Biología Computacional, Dpto. de Desarrollo Biotecnológico, Instituto de Higiene, Facultad de Medicina, UdelaR, Montevideo, Uruguay
392 Área Genética, Facultad de Veterinaria, Universidad de la República, Montevideo, Uruguay
393 rdf:type schema:Organization
394 https://www.grid.ac/institutes/grid.253559.d schema:alternateName California State University, Fullerton
395 schema:name Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA
396 rdf:type schema:Organization
397 https://www.grid.ac/institutes/grid.412714.5 schema:alternateName Hospital de Clínicas "José de San Martín"
398 schema:name Laboratorio de Bacteriología Clínica, Departamento de Bioquímica Clínica, Hospital de Clínicas José de San Martín, Facultad de Farmacia y Bioquímica, Buenos Aires, Argentina
399 rdf:type schema:Organization
400 https://www.grid.ac/institutes/grid.67105.35 schema:alternateName Case Western Reserve University
401 schema:name CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (Case VA CARES), Cleveland, Ohio, USA
402 Departments of Medicine, Pharmacology, Molecular Biology and Microbiology, Biochemistry, Proteomics and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
403 Medical Service and GRECC, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA
404 rdf:type schema:Organization
405 https://www.grid.ac/institutes/grid.7345.5 schema:alternateName University of Buenos Aires
406 schema:name Instituto de Microbiología y Parasitología Médica (IMPaM, UBA-CONICET), Facultad de Medicina, Universidad de Buenos, Aires, Argentina
407 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...