Asymptomatic versus Symptomatic Patients with Severe Aortic Stenosis View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-12

AUTHORS

Norio Kanamori, Tomohiko Taniguchi, Takeshi Morimoto, Hiroki Shiomi, Kenji Ando, Koichiro Murata, Takeshi Kitai, Yuichi Kawase, Chisato Izumi, Makoto Miyake, Hirokazu Mitsuoka, Masashi Kato, Yutaka Hirano, Shintaro Matsuda, Kazuya Nagao, Tsukasa Inada, Hiroshi Mabuchi, Yasuyo Takeuchi, Keiichiro Yamane, Mamoru Toyofuku, Mitsuru Ishii, Eri Minamino-Muta, Takao Kato, Moriaki Inoko, Tomoyuki Ikeda, Akihiro Komasa, Katsuhisa Ishii, Kozo Hotta, Nobuya Higashitani, Yoshihiro Kato, Yasutaka Inuzuka, Chiyo Maeda, Toshikazu Jinnai, Yuko Morikami, Naritatsu Saito, Kenji Minatoya, Takeshi Aoyama, Takeshi Kimura,

ABSTRACT

It is unknown how much different are the clinical outcomes between asymptomatic and symptomatic patients with severe aortic stenosis (AS). In the CURRENT AS registry enrolling 3,815 consecutive patients with severe AS, we compared the long-term outcomes between 1808 asymptomatic and 1215 symptomatic patients (exertional dyspnea: N = 813, syncope: N = 136, and angina: N = 266) without heart failure (HF) hospitalization. Symptomatic patients had greater AS severity, and more depressed left ventricular function than asymptomatic patients without much difference in other baseline characteristics. During a median follow-up of 3.2 years, aortic valve replacement (AVR) was performed in 62% of symptomatic patients, and 38% of asymptomatic patients. The cumulative 5-year incidences for the primary outcome measure (a composite of aortic valve-related death or HF hospitalization) was higher in symptomatic patients than in asymptomatic patients (32.3% versus 27.6%, P < 0.001). After adjusting for AVR and other variables, the greater risk of symptomatic relative to asymptomatic patients for the primary outcome measure was significant (hazard ratio 1.64, 95% confidence interval 1.41-1.96, P < 0.001). In conclusions, the excess risk of symptomatic relative to asymptomatic patients with severe AS for the aortic valve-related event was significant. However, the prevalence of AVR in symptomatic patients was not optimal. More... »

PAGES

10080

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41598-018-28162-x

DOI

http://dx.doi.org/10.1038/s41598-018-28162-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1105228735

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29973671


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Shimada Municipal Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415744.7", 
          "name": [
            "Division of Cardiology, Shimada Municipal Hospital, Shimada, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kanamori", 
        "givenName": "Norio", 
        "id": "sg:person.0670237621.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0670237621.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kyoto University", 
          "id": "https://www.grid.ac/institutes/grid.258799.8", 
          "name": [
            "Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Taniguchi", 
        "givenName": "Tomohiko", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hyogo College of Medicine", 
          "id": "https://www.grid.ac/institutes/grid.272264.7", 
          "name": [
            "Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Morimoto", 
        "givenName": "Takeshi", 
        "id": "sg:person.011273662612.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011273662612.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kyoto University", 
          "id": "https://www.grid.ac/institutes/grid.258799.8", 
          "name": [
            "Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shiomi", 
        "givenName": "Hiroki", 
        "id": "sg:person.01272152120.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272152120.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kokura Memorial Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415432.5", 
          "name": [
            "Department of Cardiology, Kokura Memorial Hospital, Kokura, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ando", 
        "givenName": "Kenji", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Cardiology, Shizuoka City Shizuoka Hospital, Shizuoka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Murata", 
        "givenName": "Koichiro", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kobe City Medical Center General Hospital", 
          "id": "https://www.grid.ac/institutes/grid.410843.a", 
          "name": [
            "Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Kobe, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kitai", 
        "givenName": "Takeshi", 
        "id": "sg:person.0764054232.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0764054232.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kurashiki Central Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415565.6", 
          "name": [
            "Department of Cardiovascular Medicine, Kurashiki Central Hospital, Kurashiki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kawase", 
        "givenName": "Yuichi", 
        "id": "sg:person.011555343341.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011555343341.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tenri Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416952.d", 
          "name": [
            "Department of Cardiology, Tenri Hospital, Tenri, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Izumi", 
        "givenName": "Chisato", 
        "id": "sg:person.01153713660.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01153713660.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tenri Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416952.d", 
          "name": [
            "Department of Cardiology, Tenri Hospital, Tenri, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Miyake", 
        "givenName": "Makoto", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kindai University", 
          "id": "https://www.grid.ac/institutes/grid.258622.9", 
          "name": [
            "Division of Cardiology, Nara Hospital, Kinki University Faculty of Medicine, Ikoma, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mitsuoka", 
        "givenName": "Hirokazu", 
        "id": "sg:person.01002135552.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01002135552.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mitsubishi Kyoto Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415977.9", 
          "name": [
            "Department of Cardiology, Mitsubishi Kyoto Hospital, Kyoto, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kato", 
        "givenName": "Masashi", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kindai University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413111.7", 
          "name": [
            "Department of Cardiology, Kinki University Hospital, Osakasayama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hirano", 
        "givenName": "Yutaka", 
        "id": "sg:person.01274004044.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274004044.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kyoto University", 
          "id": "https://www.grid.ac/institutes/grid.258799.8", 
          "name": [
            "Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matsuda", 
        "givenName": "Shintaro", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Osaka Red Cross Hospital", 
          "id": "https://www.grid.ac/institutes/grid.417000.2", 
          "name": [
            "Department of Cardiovascular Center, Osaka Red Cross Hospital, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nagao", 
        "givenName": "Kazuya", 
        "id": "sg:person.01252674654.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01252674654.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Osaka Red Cross Hospital", 
          "id": "https://www.grid.ac/institutes/grid.417000.2", 
          "name": [
            "Department of Cardiovascular Center, Osaka Red Cross Hospital, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Inada", 
        "givenName": "Tsukasa", 
        "id": "sg:person.01354704317.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354704317.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Cardiology, Koto Memorial Hospital, Higashiomi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mabuchi", 
        "givenName": "Hiroshi", 
        "id": "sg:person.010661377710.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010661377710.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Shizuoka General Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415804.c", 
          "name": [
            "Department of Cardiology, Shizuoka General Hospital, Shizuoka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Takeuchi", 
        "givenName": "Yasuyo", 
        "id": "sg:person.01056442521.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056442521.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nishi Kobe Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.416289.0", 
          "name": [
            "Department of Cardiology, Nishikobe Medical Center, Kobe, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yamane", 
        "givenName": "Keiichiro", 
        "id": "sg:person.01124555721.96", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124555721.96"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Japanese Red Cross Society Wakayama Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.414936.d", 
          "name": [
            "Department of Cardiology, Japanese Red Cross Wakayama Medical Center, Wakayama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Toyofuku", 
        "givenName": "Mamoru", 
        "id": "sg:person.0626560217.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626560217.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kyoto Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.410835.b", 
          "name": [
            "Department of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ishii", 
        "givenName": "Mitsuru", 
        "id": "sg:person.01214477325.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01214477325.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kyoto University", 
          "id": "https://www.grid.ac/institutes/grid.258799.8", 
          "name": [
            "Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Minamino-Muta", 
        "givenName": "Eri", 
        "id": "sg:person.01014453411.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014453411.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kyoto University", 
          "id": "https://www.grid.ac/institutes/grid.258799.8", 
          "name": [
            "Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kato", 
        "givenName": "Takao", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kitano Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415392.8", 
          "name": [
            "Cardiovascular Center, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Inoko", 
        "givenName": "Moriaki", 
        "id": "sg:person.01247462056.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01247462056.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Cardiology, Hikone Municipal Hospital, Hikone, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ikeda", 
        "givenName": "Tomoyuki", 
        "id": "sg:person.0677742021.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677742021.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Electric Power Hospital", 
          "id": "https://www.grid.ac/institutes/grid.414973.c", 
          "name": [
            "Department of Cardiology, Kansai Electric Power Hospital, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Komasa", 
        "givenName": "Akihiro", 
        "id": "sg:person.010272017325.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010272017325.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Electric Power Hospital", 
          "id": "https://www.grid.ac/institutes/grid.414973.c", 
          "name": [
            "Department of Cardiology, Kansai Electric Power Hospital, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ishii", 
        "givenName": "Katsuhisa", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Cardiology, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hotta", 
        "givenName": "Kozo", 
        "id": "sg:person.010005447177.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010005447177.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Higashitani", 
        "givenName": "Nobuya", 
        "id": "sg:person.010122203773.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010122203773.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Cardiology, Saiseikai Noe Hospital, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kato", 
        "givenName": "Yoshihiro", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Shiga Medical Center for Adults", 
          "id": "https://www.grid.ac/institutes/grid.416499.7", 
          "name": [
            "Department of Cardiology, Shiga Medical Center for Adults, Moriyama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Inuzuka", 
        "givenName": "Yasutaka", 
        "id": "sg:person.01003162532.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01003162532.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hamamatsu Rosai Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413556.0", 
          "name": [
            "Department of Cardiology, Hamamatsu Rosai Hospital, Hamamatsu, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maeda", 
        "givenName": "Chiyo", 
        "id": "sg:person.0670701430.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0670701430.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jinnai", 
        "givenName": "Toshikazu", 
        "id": "sg:person.01361074021.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361074021.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Cardiology, Hirakata Kohsai Hospital, Hirakata, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Morikami", 
        "givenName": "Yuko", 
        "id": "sg:person.0635467721.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0635467721.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kyoto University", 
          "id": "https://www.grid.ac/institutes/grid.258799.8", 
          "name": [
            "Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Saito", 
        "givenName": "Naritatsu", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kyoto University", 
          "id": "https://www.grid.ac/institutes/grid.258799.8", 
          "name": [
            "Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Minatoya", 
        "givenName": "Kenji", 
        "id": "sg:person.01141037306.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141037306.94"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Shimada Municipal Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415744.7", 
          "name": [
            "Division of Cardiology, Shimada Municipal Hospital, Shimada, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Aoyama", 
        "givenName": "Takeshi", 
        "id": "sg:person.01231313015.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01231313015.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kyoto University", 
          "id": "https://www.grid.ac/institutes/grid.258799.8", 
          "name": [
            "Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kimura", 
        "givenName": "Takeshi", 
        "type": "Person"
      }, 
      {}
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/s0140-6736(15)60308-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003957461"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijcard.2016.11.092", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006555552"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijcard.2016.11.092", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006555552"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/eurheartj/ehs109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008657937"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2015.10.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011616449"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/eurheartj/ehi471", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013647440"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.114.012906", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020461056"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.114.012906", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020461056"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.114.012906", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020461056"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2010.12.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022379192"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.athoracsur.2013.08.059", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026492604"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circoutcomes.112.966002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028530213"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circoutcomes.112.966002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028530213"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/eurheartj/ehq076", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029847135"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/eurheartj/ehq076", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029847135"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2012.09.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030012723"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.109.926873", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030967642"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/cir.0000000000000031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039783709"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/cir.0000000000000031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039783709"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/cir.0000000000000031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039783709"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.0000441139.02102.80", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040460683"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.0000441139.02102.80", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040460683"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(15)60290-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043110578"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0002-9149(88)91317-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043554327"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jcmg.2012.10.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045145123"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/hrt.82.2.143", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048185162"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circoutcomes.109.848259", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048504695"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circoutcomes.109.848259", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048504695"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11748-016-0622-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051922268", 
          "https://doi.org/10.1007/s11748-016-0622-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11748-016-0695-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052417280", 
          "https://doi.org/10.1007/s11748-016-0695-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11748-016-0695-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052417280", 
          "https://doi.org/10.1007/s11748-016-0695-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.38.1s5.v-61", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063335393"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/jaha.115.003146", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079265674"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1253/circj.cj-16-0998", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083735479"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1253/circj.cj-16-1244", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084750919"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circinterventions.116.004796", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085466420"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circinterventions.116.004796", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085466420"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/heartjnl-2016-311022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090398205"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/jaha.116.004961", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090695035"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/jaha.117.005524", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090885345"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-12", 
    "datePublishedReg": "2018-12-01", 
    "description": "It is unknown how much different are the clinical outcomes between asymptomatic and symptomatic patients with severe aortic stenosis (AS). In the CURRENT AS registry enrolling 3,815 consecutive patients with severe AS, we compared the long-term outcomes between 1808 asymptomatic and 1215 symptomatic patients (exertional dyspnea: N\u2009=\u2009813, syncope: N\u2009=\u2009136, and angina: N\u2009=\u2009266) without heart failure (HF) hospitalization. Symptomatic patients had greater AS severity, and more depressed left ventricular function than asymptomatic patients without much difference in other baseline characteristics. During a median follow-up of 3.2 years, aortic valve replacement (AVR) was performed in 62% of symptomatic patients, and 38% of asymptomatic patients. The cumulative 5-year incidences for the primary outcome measure (a composite of aortic valve-related death or HF hospitalization) was higher in symptomatic patients than in asymptomatic patients (32.3% versus 27.6%, P\u2009<\u20090.001). After adjusting for AVR and other variables, the greater risk of symptomatic relative to asymptomatic patients for the primary outcome measure was significant (hazard ratio 1.64, 95% confidence interval 1.41-1.96, P\u2009<\u20090.001). In conclusions, the excess risk of symptomatic relative to asymptomatic patients with severe AS for the aortic valve-related event was significant. However, the prevalence of AVR in symptomatic patients was not optimal.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/s41598-018-28162-x", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1045337", 
        "issn": [
          "2045-2322"
        ], 
        "name": "Scientific Reports", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "8"
      }
    ], 
    "name": "Asymptomatic versus Symptomatic Patients with Severe Aortic Stenosis", 
    "pagination": "10080", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "14033115c776ac8b956af8b05b9cf2931b622ae24ccae200255ce9dc4e216762"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "29973671"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101563288"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s41598-018-28162-x"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1105228735"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s41598-018-28162-x", 
      "https://app.dimensions.ai/details/publication/pub.1105228735"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T01:17", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8697_00000571.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/s41598-018-28162-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-28162-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-28162-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-28162-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-28162-x'


 

This table displays all metadata directly associated to this object as RDF triples.

478 TRIPLES      21 PREDICATES      58 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s41598-018-28162-x schema:about anzsrc-for:11
2 anzsrc-for:1102
3 schema:author Nece3f9e316204e8ab051abe951a55c1d
4 schema:citation sg:pub.10.1007/s11748-016-0622-7
5 sg:pub.10.1007/s11748-016-0695-3
6 https://doi.org/10.1016/0002-9149(88)91317-3
7 https://doi.org/10.1016/j.athoracsur.2013.08.059
8 https://doi.org/10.1016/j.ijcard.2016.11.092
9 https://doi.org/10.1016/j.jacc.2010.12.005
10 https://doi.org/10.1016/j.jacc.2012.09.001
11 https://doi.org/10.1016/j.jacc.2015.10.001
12 https://doi.org/10.1016/j.jcmg.2012.10.013
13 https://doi.org/10.1016/s0140-6736(15)60290-2
14 https://doi.org/10.1016/s0140-6736(15)60308-7
15 https://doi.org/10.1093/eurheartj/ehi471
16 https://doi.org/10.1093/eurheartj/ehq076
17 https://doi.org/10.1093/eurheartj/ehs109
18 https://doi.org/10.1136/heartjnl-2016-311022
19 https://doi.org/10.1136/hrt.82.2.143
20 https://doi.org/10.1161/01.cir.0000441139.02102.80
21 https://doi.org/10.1161/01.cir.38.1s5.v-61
22 https://doi.org/10.1161/cir.0000000000000031
23 https://doi.org/10.1161/circinterventions.116.004796
24 https://doi.org/10.1161/circoutcomes.109.848259
25 https://doi.org/10.1161/circoutcomes.112.966002
26 https://doi.org/10.1161/circulationaha.109.926873
27 https://doi.org/10.1161/circulationaha.114.012906
28 https://doi.org/10.1161/jaha.115.003146
29 https://doi.org/10.1161/jaha.116.004961
30 https://doi.org/10.1161/jaha.117.005524
31 https://doi.org/10.1253/circj.cj-16-0998
32 https://doi.org/10.1253/circj.cj-16-1244
33 schema:datePublished 2018-12
34 schema:datePublishedReg 2018-12-01
35 schema:description It is unknown how much different are the clinical outcomes between asymptomatic and symptomatic patients with severe aortic stenosis (AS). In the CURRENT AS registry enrolling 3,815 consecutive patients with severe AS, we compared the long-term outcomes between 1808 asymptomatic and 1215 symptomatic patients (exertional dyspnea: N = 813, syncope: N = 136, and angina: N = 266) without heart failure (HF) hospitalization. Symptomatic patients had greater AS severity, and more depressed left ventricular function than asymptomatic patients without much difference in other baseline characteristics. During a median follow-up of 3.2 years, aortic valve replacement (AVR) was performed in 62% of symptomatic patients, and 38% of asymptomatic patients. The cumulative 5-year incidences for the primary outcome measure (a composite of aortic valve-related death or HF hospitalization) was higher in symptomatic patients than in asymptomatic patients (32.3% versus 27.6%, P < 0.001). After adjusting for AVR and other variables, the greater risk of symptomatic relative to asymptomatic patients for the primary outcome measure was significant (hazard ratio 1.64, 95% confidence interval 1.41-1.96, P < 0.001). In conclusions, the excess risk of symptomatic relative to asymptomatic patients with severe AS for the aortic valve-related event was significant. However, the prevalence of AVR in symptomatic patients was not optimal.
36 schema:genre research_article
37 schema:inLanguage en
38 schema:isAccessibleForFree true
39 schema:isPartOf N6966ddcb2e604bcca5d2c66493513792
40 N98634876c33f4717a22c9a909f46da50
41 sg:journal.1045337
42 schema:name Asymptomatic versus Symptomatic Patients with Severe Aortic Stenosis
43 schema:pagination 10080
44 schema:productId N172b234b593c4fdb94058e577c22d5c2
45 N3ba9eb6b6f9c4ffc9313c1b9c5187066
46 N4117d1127f544556a21121414da43124
47 N44c3ce90f7c54625acf4237303650a95
48 N8efd774ba9ba43009a6479ec5542e582
49 schema:sameAs https://app.dimensions.ai/details/publication/pub.1105228735
50 https://doi.org/10.1038/s41598-018-28162-x
51 schema:sdDatePublished 2019-04-11T01:17
52 schema:sdLicense https://scigraph.springernature.com/explorer/license/
53 schema:sdPublisher N5e160afe503a4f0bb11ccb2f15d7132a
54 schema:url https://www.nature.com/articles/s41598-018-28162-x
55 sgo:license sg:explorer/license/
56 sgo:sdDataset articles
57 rdf:type schema:ScholarlyArticle
58 N010a94e6a1d04d788ae5ca11e30da52a schema:affiliation https://www.grid.ac/institutes/grid.415977.9
59 schema:familyName Kato
60 schema:givenName Masashi
61 rdf:type schema:Person
62 N07ed4b16d2434086adc8ca414a3c4f96 rdf:first Nfd18e5523052425cba01c4dacdc6844c
63 rdf:rest N961ee8a3509b4818be2b4b3d0c1e7822
64 N0f1fe3501d2e46bbad4d0e7bbb631af4 rdf:first sg:person.0635467721.48
65 rdf:rest Nad41a49a5e664263be7646efeb8b958f
66 N172b234b593c4fdb94058e577c22d5c2 schema:name doi
67 schema:value 10.1038/s41598-018-28162-x
68 rdf:type schema:PropertyValue
69 N19ad2d7a16084dec9c98f194eced0760 rdf:first sg:person.01252674654.22
70 rdf:rest N504cdfdb5a3c4aad85879196cfa80c90
71 N1ec4c11f595042779df122aca3ba5c32 schema:name Department of Cardiology, Koto Memorial Hospital, Higashiomi, Japan
72 rdf:type schema:Organization
73 N27536dbdd57946f18920f4254fb21134 rdf:first sg:person.0670701430.09
74 rdf:rest N42c114707896484c9fa39f8bf538afd1
75 N2f7fb4309d484b87a30318058df96852 rdf:first sg:person.01141037306.94
76 rdf:rest N46ed5bfdcfa048f5be208ae7a3bb14eb
77 N306eeca6ca0944e994d7ff0f1abfe1ef schema:name Department of Cardiology, Saiseikai Noe Hospital, Osaka, Japan
78 rdf:type schema:Organization
79 N36d48063b0f14c7d9e2de9f744dbd6aa rdf:first N708c96d7b57443f4bbefc84d7383f60c
80 rdf:rest Na40ecb452d084c93a49c4dc3f20b29a9
81 N3a01cae61add4e40a73c1d697714ed16 schema:affiliation https://www.grid.ac/institutes/grid.258799.8
82 schema:familyName Kato
83 schema:givenName Takao
84 rdf:type schema:Person
85 N3ba9eb6b6f9c4ffc9313c1b9c5187066 schema:name pubmed_id
86 schema:value 29973671
87 rdf:type schema:PropertyValue
88 N40d32216b85047c7ae1924c8e879aa66 rdf:first Nf177b9fd32054a5f91647d983dc71d5d
89 rdf:rest N8c171320c5f241e4933e95ca67d9ed3e
90 N4117d1127f544556a21121414da43124 schema:name dimensions_id
91 schema:value pub.1105228735
92 rdf:type schema:PropertyValue
93 N42c114707896484c9fa39f8bf538afd1 rdf:first sg:person.01361074021.09
94 rdf:rest N0f1fe3501d2e46bbad4d0e7bbb631af4
95 N44c3ce90f7c54625acf4237303650a95 schema:name readcube_id
96 schema:value 14033115c776ac8b956af8b05b9cf2931b622ae24ccae200255ce9dc4e216762
97 rdf:type schema:PropertyValue
98 N46ed5bfdcfa048f5be208ae7a3bb14eb rdf:first sg:person.01231313015.40
99 rdf:rest N7fc11f80021645b0a7cca7a92334cfef
100 N47b5e6235ffe40d7982e523387c86f77 schema:name Department of Cardiology, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Japan
101 rdf:type schema:Organization
102 N504cdfdb5a3c4aad85879196cfa80c90 rdf:first sg:person.01354704317.72
103 rdf:rest Nf6d2d6ca9fe9415685ca1ef0821754ce
104 N5e160afe503a4f0bb11ccb2f15d7132a schema:name Springer Nature - SN SciGraph project
105 rdf:type schema:Organization
106 N63aa16f0538e47b48e32a6792b0b6ef1 schema:affiliation https://www.grid.ac/institutes/grid.416952.d
107 schema:familyName Miyake
108 schema:givenName Makoto
109 rdf:type schema:Person
110 N644b4d4c18d64a52b220facd1861b004 schema:name Department of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan
111 rdf:type schema:Organization
112 N6966ddcb2e604bcca5d2c66493513792 schema:volumeNumber 8
113 rdf:type schema:PublicationVolume
114 N6b138f40816b47d9ba09afc5db209385 rdf:first sg:person.01014453411.50
115 rdf:rest N7e10c57e5f1649e0858005db90c5df9b
116 N6b3a0b8817d2495cbd5afba181626173 schema:name Department of Cardiology, Shizuoka City Shizuoka Hospital, Shizuoka, Japan
117 rdf:type schema:Organization
118 N708c96d7b57443f4bbefc84d7383f60c schema:affiliation https://www.grid.ac/institutes/grid.414973.c
119 schema:familyName Ishii
120 schema:givenName Katsuhisa
121 rdf:type schema:Person
122 N74d990ff45e54cfc8d649974ff3d861d rdf:first sg:person.011273662612.03
123 rdf:rest Nf1b23c6c145e416f8a6398786262f05f
124 N7991723b4f2846e1b7a6f4e58fe9ca05 schema:name Department of Cardiology, Hirakata Kohsai Hospital, Hirakata, Japan
125 rdf:type schema:Organization
126 N7e10c57e5f1649e0858005db90c5df9b rdf:first N3a01cae61add4e40a73c1d697714ed16
127 rdf:rest Ne5fc6e90c4bc44688d8e9740a164eb7f
128 N7fc11f80021645b0a7cca7a92334cfef rdf:first Nf744d252bec14581b1ea46dfa1159b24
129 rdf:rest Nbe0494ce11fb4e2fb6d3f81aee7e2372
130 N804fd76a5aa34a328ec1131446af6374 rdf:first sg:person.011555343341.98
131 rdf:rest Na88147bca3fb465d9962a7bb9a9031f3
132 N8120e02c1cff4ce8b468ad910d8a442f rdf:first Nff8c30a1f099455bad29d9aea26ece92
133 rdf:rest N19ad2d7a16084dec9c98f194eced0760
134 N8148e064865240e39f28d0b60918b73f schema:name Department of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan
135 rdf:type schema:Organization
136 N875d1c491c2245aaba810aa5e6acd818 rdf:first sg:person.01124555721.96
137 rdf:rest N9d3b424d07a94aeb95879784a630a7d7
138 N87d8bff3ee4043e0a2920065f362cebc schema:name Department of Cardiology, Hikone Municipal Hospital, Hikone, Japan
139 rdf:type schema:Organization
140 N8c171320c5f241e4933e95ca67d9ed3e rdf:first sg:person.01003162532.11
141 rdf:rest N27536dbdd57946f18920f4254fb21134
142 N8efd774ba9ba43009a6479ec5542e582 schema:name nlm_unique_id
143 schema:value 101563288
144 rdf:type schema:PropertyValue
145 N961ee8a3509b4818be2b4b3d0c1e7822 rdf:first sg:person.0764054232.72
146 rdf:rest N804fd76a5aa34a328ec1131446af6374
147 N98634876c33f4717a22c9a909f46da50 schema:issueNumber 1
148 rdf:type schema:PublicationIssue
149 N9d3b424d07a94aeb95879784a630a7d7 rdf:first sg:person.0626560217.70
150 rdf:rest Nebe489e85a5d44ecbdfca0bf20b3629a
151 Na20f3d2fab36495aa91894675d3591bd rdf:first sg:person.01056442521.28
152 rdf:rest N875d1c491c2245aaba810aa5e6acd818
153 Na40ecb452d084c93a49c4dc3f20b29a9 rdf:first sg:person.010005447177.43
154 rdf:rest Nd776496b934746609983ee95e0d70644
155 Na493909719a8497c94a63578d596a80b rdf:first sg:person.01274004044.18
156 rdf:rest N8120e02c1cff4ce8b468ad910d8a442f
157 Na88147bca3fb465d9962a7bb9a9031f3 rdf:first sg:person.01153713660.72
158 rdf:rest Nc34f6cbe43194e479ef64f4b01ab2f71
159 Nad41a49a5e664263be7646efeb8b958f rdf:first Nd0aebb2d4efc4290a66258d73e69c043
160 rdf:rest N2f7fb4309d484b87a30318058df96852
161 Nba5e5f2680854bbfb55a216cbd618154 schema:affiliation https://www.grid.ac/institutes/grid.415432.5
162 schema:familyName Ando
163 schema:givenName Kenji
164 rdf:type schema:Person
165 Nbe0494ce11fb4e2fb6d3f81aee7e2372 rdf:first N87dbb35732a84a89a6840db09047316f
166 rdf:rest rdf:nil
167 Nbf4d14b270254c9d865b8c717caa2478 rdf:first Nfdf4cd15708d403f8eff6cb5c65c412a
168 rdf:rest N74d990ff45e54cfc8d649974ff3d861d
169 Nc34f6cbe43194e479ef64f4b01ab2f71 rdf:first N63aa16f0538e47b48e32a6792b0b6ef1
170 rdf:rest Ne21f7e02888a495face12967562172d4
171 Nd0aebb2d4efc4290a66258d73e69c043 schema:affiliation https://www.grid.ac/institutes/grid.258799.8
172 schema:familyName Saito
173 schema:givenName Naritatsu
174 rdf:type schema:Person
175 Nd4d610a191e745cd87f1fdad5481e949 rdf:first sg:person.0677742021.29
176 rdf:rest Nf69cf8fad2014b459c90b90b69f7a66e
177 Nd776496b934746609983ee95e0d70644 rdf:first sg:person.010122203773.13
178 rdf:rest N40d32216b85047c7ae1924c8e879aa66
179 Ne21f7e02888a495face12967562172d4 rdf:first sg:person.01002135552.21
180 rdf:rest Ne457f1779558436581e3c0d6ff9d703c
181 Ne457f1779558436581e3c0d6ff9d703c rdf:first N010a94e6a1d04d788ae5ca11e30da52a
182 rdf:rest Na493909719a8497c94a63578d596a80b
183 Ne5fc6e90c4bc44688d8e9740a164eb7f rdf:first sg:person.01247462056.75
184 rdf:rest Nd4d610a191e745cd87f1fdad5481e949
185 Ne89e508905744c73bad4d3bc0e0352b4 rdf:first Nba5e5f2680854bbfb55a216cbd618154
186 rdf:rest N07ed4b16d2434086adc8ca414a3c4f96
187 Nebe489e85a5d44ecbdfca0bf20b3629a rdf:first sg:person.01214477325.54
188 rdf:rest N6b138f40816b47d9ba09afc5db209385
189 Nece3f9e316204e8ab051abe951a55c1d rdf:first sg:person.0670237621.72
190 rdf:rest Nbf4d14b270254c9d865b8c717caa2478
191 Nf177b9fd32054a5f91647d983dc71d5d schema:affiliation N306eeca6ca0944e994d7ff0f1abfe1ef
192 schema:familyName Kato
193 schema:givenName Yoshihiro
194 rdf:type schema:Person
195 Nf1b23c6c145e416f8a6398786262f05f rdf:first sg:person.01272152120.47
196 rdf:rest Ne89e508905744c73bad4d3bc0e0352b4
197 Nf69cf8fad2014b459c90b90b69f7a66e rdf:first sg:person.010272017325.12
198 rdf:rest N36d48063b0f14c7d9e2de9f744dbd6aa
199 Nf6d2d6ca9fe9415685ca1ef0821754ce rdf:first sg:person.010661377710.98
200 rdf:rest Na20f3d2fab36495aa91894675d3591bd
201 Nf744d252bec14581b1ea46dfa1159b24 schema:affiliation https://www.grid.ac/institutes/grid.258799.8
202 schema:familyName Kimura
203 schema:givenName Takeshi
204 rdf:type schema:Person
205 Nfd18e5523052425cba01c4dacdc6844c schema:affiliation N6b3a0b8817d2495cbd5afba181626173
206 schema:familyName Murata
207 schema:givenName Koichiro
208 rdf:type schema:Person
209 Nfdf4cd15708d403f8eff6cb5c65c412a schema:affiliation https://www.grid.ac/institutes/grid.258799.8
210 schema:familyName Taniguchi
211 schema:givenName Tomohiko
212 rdf:type schema:Person
213 Nff8c30a1f099455bad29d9aea26ece92 schema:affiliation https://www.grid.ac/institutes/grid.258799.8
214 schema:familyName Matsuda
215 schema:givenName Shintaro
216 rdf:type schema:Person
217 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
218 schema:name Medical and Health Sciences
219 rdf:type schema:DefinedTerm
220 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
221 schema:name Cardiorespiratory Medicine and Haematology
222 rdf:type schema:DefinedTerm
223 sg:journal.1045337 schema:issn 2045-2322
224 schema:name Scientific Reports
225 rdf:type schema:Periodical
226 sg:person.010005447177.43 schema:affiliation N47b5e6235ffe40d7982e523387c86f77
227 schema:familyName Hotta
228 schema:givenName Kozo
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010005447177.43
230 rdf:type schema:Person
231 sg:person.01002135552.21 schema:affiliation https://www.grid.ac/institutes/grid.258622.9
232 schema:familyName Mitsuoka
233 schema:givenName Hirokazu
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01002135552.21
235 rdf:type schema:Person
236 sg:person.01003162532.11 schema:affiliation https://www.grid.ac/institutes/grid.416499.7
237 schema:familyName Inuzuka
238 schema:givenName Yasutaka
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01003162532.11
240 rdf:type schema:Person
241 sg:person.010122203773.13 schema:affiliation N8148e064865240e39f28d0b60918b73f
242 schema:familyName Higashitani
243 schema:givenName Nobuya
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010122203773.13
245 rdf:type schema:Person
246 sg:person.01014453411.50 schema:affiliation https://www.grid.ac/institutes/grid.258799.8
247 schema:familyName Minamino-Muta
248 schema:givenName Eri
249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014453411.50
250 rdf:type schema:Person
251 sg:person.010272017325.12 schema:affiliation https://www.grid.ac/institutes/grid.414973.c
252 schema:familyName Komasa
253 schema:givenName Akihiro
254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010272017325.12
255 rdf:type schema:Person
256 sg:person.01056442521.28 schema:affiliation https://www.grid.ac/institutes/grid.415804.c
257 schema:familyName Takeuchi
258 schema:givenName Yasuyo
259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056442521.28
260 rdf:type schema:Person
261 sg:person.010661377710.98 schema:affiliation N1ec4c11f595042779df122aca3ba5c32
262 schema:familyName Mabuchi
263 schema:givenName Hiroshi
264 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010661377710.98
265 rdf:type schema:Person
266 sg:person.01124555721.96 schema:affiliation https://www.grid.ac/institutes/grid.416289.0
267 schema:familyName Yamane
268 schema:givenName Keiichiro
269 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124555721.96
270 rdf:type schema:Person
271 sg:person.011273662612.03 schema:affiliation https://www.grid.ac/institutes/grid.272264.7
272 schema:familyName Morimoto
273 schema:givenName Takeshi
274 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011273662612.03
275 rdf:type schema:Person
276 sg:person.01141037306.94 schema:affiliation https://www.grid.ac/institutes/grid.258799.8
277 schema:familyName Minatoya
278 schema:givenName Kenji
279 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141037306.94
280 rdf:type schema:Person
281 sg:person.01153713660.72 schema:affiliation https://www.grid.ac/institutes/grid.416952.d
282 schema:familyName Izumi
283 schema:givenName Chisato
284 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01153713660.72
285 rdf:type schema:Person
286 sg:person.011555343341.98 schema:affiliation https://www.grid.ac/institutes/grid.415565.6
287 schema:familyName Kawase
288 schema:givenName Yuichi
289 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011555343341.98
290 rdf:type schema:Person
291 sg:person.01214477325.54 schema:affiliation https://www.grid.ac/institutes/grid.410835.b
292 schema:familyName Ishii
293 schema:givenName Mitsuru
294 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01214477325.54
295 rdf:type schema:Person
296 sg:person.01231313015.40 schema:affiliation https://www.grid.ac/institutes/grid.415744.7
297 schema:familyName Aoyama
298 schema:givenName Takeshi
299 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01231313015.40
300 rdf:type schema:Person
301 sg:person.01247462056.75 schema:affiliation https://www.grid.ac/institutes/grid.415392.8
302 schema:familyName Inoko
303 schema:givenName Moriaki
304 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01247462056.75
305 rdf:type schema:Person
306 sg:person.01252674654.22 schema:affiliation https://www.grid.ac/institutes/grid.417000.2
307 schema:familyName Nagao
308 schema:givenName Kazuya
309 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01252674654.22
310 rdf:type schema:Person
311 sg:person.01272152120.47 schema:affiliation https://www.grid.ac/institutes/grid.258799.8
312 schema:familyName Shiomi
313 schema:givenName Hiroki
314 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272152120.47
315 rdf:type schema:Person
316 sg:person.01274004044.18 schema:affiliation https://www.grid.ac/institutes/grid.413111.7
317 schema:familyName Hirano
318 schema:givenName Yutaka
319 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274004044.18
320 rdf:type schema:Person
321 sg:person.01354704317.72 schema:affiliation https://www.grid.ac/institutes/grid.417000.2
322 schema:familyName Inada
323 schema:givenName Tsukasa
324 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354704317.72
325 rdf:type schema:Person
326 sg:person.01361074021.09 schema:affiliation N644b4d4c18d64a52b220facd1861b004
327 schema:familyName Jinnai
328 schema:givenName Toshikazu
329 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361074021.09
330 rdf:type schema:Person
331 sg:person.0626560217.70 schema:affiliation https://www.grid.ac/institutes/grid.414936.d
332 schema:familyName Toyofuku
333 schema:givenName Mamoru
334 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626560217.70
335 rdf:type schema:Person
336 sg:person.0635467721.48 schema:affiliation N7991723b4f2846e1b7a6f4e58fe9ca05
337 schema:familyName Morikami
338 schema:givenName Yuko
339 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0635467721.48
340 rdf:type schema:Person
341 sg:person.0670237621.72 schema:affiliation https://www.grid.ac/institutes/grid.415744.7
342 schema:familyName Kanamori
343 schema:givenName Norio
344 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0670237621.72
345 rdf:type schema:Person
346 sg:person.0670701430.09 schema:affiliation https://www.grid.ac/institutes/grid.413556.0
347 schema:familyName Maeda
348 schema:givenName Chiyo
349 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0670701430.09
350 rdf:type schema:Person
351 sg:person.0677742021.29 schema:affiliation N87d8bff3ee4043e0a2920065f362cebc
352 schema:familyName Ikeda
353 schema:givenName Tomoyuki
354 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677742021.29
355 rdf:type schema:Person
356 sg:person.0764054232.72 schema:affiliation https://www.grid.ac/institutes/grid.410843.a
357 schema:familyName Kitai
358 schema:givenName Takeshi
359 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0764054232.72
360 rdf:type schema:Person
361 sg:pub.10.1007/s11748-016-0622-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051922268
362 https://doi.org/10.1007/s11748-016-0622-7
363 rdf:type schema:CreativeWork
364 sg:pub.10.1007/s11748-016-0695-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052417280
365 https://doi.org/10.1007/s11748-016-0695-3
366 rdf:type schema:CreativeWork
367 https://doi.org/10.1016/0002-9149(88)91317-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043554327
368 rdf:type schema:CreativeWork
369 https://doi.org/10.1016/j.athoracsur.2013.08.059 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026492604
370 rdf:type schema:CreativeWork
371 https://doi.org/10.1016/j.ijcard.2016.11.092 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006555552
372 rdf:type schema:CreativeWork
373 https://doi.org/10.1016/j.jacc.2010.12.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022379192
374 rdf:type schema:CreativeWork
375 https://doi.org/10.1016/j.jacc.2012.09.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030012723
376 rdf:type schema:CreativeWork
377 https://doi.org/10.1016/j.jacc.2015.10.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011616449
378 rdf:type schema:CreativeWork
379 https://doi.org/10.1016/j.jcmg.2012.10.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045145123
380 rdf:type schema:CreativeWork
381 https://doi.org/10.1016/s0140-6736(15)60290-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043110578
382 rdf:type schema:CreativeWork
383 https://doi.org/10.1016/s0140-6736(15)60308-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003957461
384 rdf:type schema:CreativeWork
385 https://doi.org/10.1093/eurheartj/ehi471 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013647440
386 rdf:type schema:CreativeWork
387 https://doi.org/10.1093/eurheartj/ehq076 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029847135
388 rdf:type schema:CreativeWork
389 https://doi.org/10.1093/eurheartj/ehs109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008657937
390 rdf:type schema:CreativeWork
391 https://doi.org/10.1136/heartjnl-2016-311022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090398205
392 rdf:type schema:CreativeWork
393 https://doi.org/10.1136/hrt.82.2.143 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048185162
394 rdf:type schema:CreativeWork
395 https://doi.org/10.1161/01.cir.0000441139.02102.80 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040460683
396 rdf:type schema:CreativeWork
397 https://doi.org/10.1161/01.cir.38.1s5.v-61 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063335393
398 rdf:type schema:CreativeWork
399 https://doi.org/10.1161/cir.0000000000000031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039783709
400 rdf:type schema:CreativeWork
401 https://doi.org/10.1161/circinterventions.116.004796 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085466420
402 rdf:type schema:CreativeWork
403 https://doi.org/10.1161/circoutcomes.109.848259 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048504695
404 rdf:type schema:CreativeWork
405 https://doi.org/10.1161/circoutcomes.112.966002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028530213
406 rdf:type schema:CreativeWork
407 https://doi.org/10.1161/circulationaha.109.926873 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030967642
408 rdf:type schema:CreativeWork
409 https://doi.org/10.1161/circulationaha.114.012906 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020461056
410 rdf:type schema:CreativeWork
411 https://doi.org/10.1161/jaha.115.003146 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079265674
412 rdf:type schema:CreativeWork
413 https://doi.org/10.1161/jaha.116.004961 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090695035
414 rdf:type schema:CreativeWork
415 https://doi.org/10.1161/jaha.117.005524 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090885345
416 rdf:type schema:CreativeWork
417 https://doi.org/10.1253/circj.cj-16-0998 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083735479
418 rdf:type schema:CreativeWork
419 https://doi.org/10.1253/circj.cj-16-1244 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084750919
420 rdf:type schema:CreativeWork
421 https://www.grid.ac/institutes/grid.258622.9 schema:alternateName Kindai University
422 schema:name Division of Cardiology, Nara Hospital, Kinki University Faculty of Medicine, Ikoma, Japan
423 rdf:type schema:Organization
424 https://www.grid.ac/institutes/grid.258799.8 schema:alternateName Kyoto University
425 schema:name Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan
426 Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
427 rdf:type schema:Organization
428 https://www.grid.ac/institutes/grid.272264.7 schema:alternateName Hyogo College of Medicine
429 schema:name Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan
430 rdf:type schema:Organization
431 https://www.grid.ac/institutes/grid.410835.b schema:alternateName Kyoto Medical Center
432 schema:name Department of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan
433 rdf:type schema:Organization
434 https://www.grid.ac/institutes/grid.410843.a schema:alternateName Kobe City Medical Center General Hospital
435 schema:name Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Kobe, Japan
436 rdf:type schema:Organization
437 https://www.grid.ac/institutes/grid.413111.7 schema:alternateName Kindai University Hospital
438 schema:name Department of Cardiology, Kinki University Hospital, Osakasayama, Japan
439 rdf:type schema:Organization
440 https://www.grid.ac/institutes/grid.413556.0 schema:alternateName Hamamatsu Rosai Hospital
441 schema:name Department of Cardiology, Hamamatsu Rosai Hospital, Hamamatsu, Japan
442 rdf:type schema:Organization
443 https://www.grid.ac/institutes/grid.414936.d schema:alternateName Japanese Red Cross Society Wakayama Medical Center
444 schema:name Department of Cardiology, Japanese Red Cross Wakayama Medical Center, Wakayama, Japan
445 rdf:type schema:Organization
446 https://www.grid.ac/institutes/grid.414973.c schema:alternateName Kansai Electric Power Hospital
447 schema:name Department of Cardiology, Kansai Electric Power Hospital, Osaka, Japan
448 rdf:type schema:Organization
449 https://www.grid.ac/institutes/grid.415392.8 schema:alternateName Kitano Hospital
450 schema:name Cardiovascular Center, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan
451 rdf:type schema:Organization
452 https://www.grid.ac/institutes/grid.415432.5 schema:alternateName Kokura Memorial Hospital
453 schema:name Department of Cardiology, Kokura Memorial Hospital, Kokura, Japan
454 rdf:type schema:Organization
455 https://www.grid.ac/institutes/grid.415565.6 schema:alternateName Kurashiki Central Hospital
456 schema:name Department of Cardiovascular Medicine, Kurashiki Central Hospital, Kurashiki, Japan
457 rdf:type schema:Organization
458 https://www.grid.ac/institutes/grid.415744.7 schema:alternateName Shimada Municipal Hospital
459 schema:name Division of Cardiology, Shimada Municipal Hospital, Shimada, Japan
460 rdf:type schema:Organization
461 https://www.grid.ac/institutes/grid.415804.c schema:alternateName Shizuoka General Hospital
462 schema:name Department of Cardiology, Shizuoka General Hospital, Shizuoka, Japan
463 rdf:type schema:Organization
464 https://www.grid.ac/institutes/grid.415977.9 schema:alternateName Mitsubishi Kyoto Hospital
465 schema:name Department of Cardiology, Mitsubishi Kyoto Hospital, Kyoto, Japan
466 rdf:type schema:Organization
467 https://www.grid.ac/institutes/grid.416289.0 schema:alternateName Nishi Kobe Medical Center
468 schema:name Department of Cardiology, Nishikobe Medical Center, Kobe, Japan
469 rdf:type schema:Organization
470 https://www.grid.ac/institutes/grid.416499.7 schema:alternateName Shiga Medical Center for Adults
471 schema:name Department of Cardiology, Shiga Medical Center for Adults, Moriyama, Japan
472 rdf:type schema:Organization
473 https://www.grid.ac/institutes/grid.416952.d schema:alternateName Tenri Hospital
474 schema:name Department of Cardiology, Tenri Hospital, Tenri, Japan
475 rdf:type schema:Organization
476 https://www.grid.ac/institutes/grid.417000.2 schema:alternateName Osaka Red Cross Hospital
477 schema:name Department of Cardiovascular Center, Osaka Red Cross Hospital, Osaka, Japan
478 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...