Polycomb Repressive Complex 2 attenuates the very high expression of the Arabidopsis gene NRT2.1 View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-12

AUTHORS

Fanny Bellegarde, Léo Herbert, David Séré, Erwann Caillieux, Jossia Boucherez, Cécile Fizames, François Roudier, Alain Gojon, Antoine Martin

ABSTRACT

PRC2 is a major regulator of gene expression in eukaryotes. It catalyzes the repressive chromatin mark H3K27me3, which leads to very low expression of target genes. NRT2.1, which encodes a key root nitrate transporter in Arabidopsis, is targeted by H3K27me3, but the function of PRC2 on NRT2.1 remains unclear. Here, we demonstrate that PRC2 directly targets and down-regulates NRT2.1, but in a context of very high transcription, in nutritional conditions where this gene is one of the most highly expressed genes in the transcriptome. Indeed, the mutation of CLF, which encodes a PRC2 subunit, leads to a loss of H3K27me3 at NRT2.1 and results, exclusively under permissive conditions for NRT2.1, in a further increase in NRT2.1 expression, and specifically in tissues where NRT2.1 is normally expressed. Therefore, our data indicates that PRC2 tempers the hyperactivity of NRT2.1 in a context of very strong transcription. This reveals an original function of PRC2 in the control of the expression of a highly expressed gene in Arabidopsis. More... »

PAGES

7905

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41598-018-26349-w

DOI

http://dx.doi.org/10.1038/s41598-018-26349-w

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1103996504

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29784958


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Biochemistry and Plant Molecular Physiology", 
          "id": "https://www.grid.ac/institutes/grid.461861.c", 
          "name": [
            "BPMP, CNRS, INRA, SupAgro, Univ. Montpellier, Montpellier, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bellegarde", 
        "givenName": "Fanny", 
        "id": "sg:person.010544441233.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010544441233.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Biochemistry and Plant Molecular Physiology", 
          "id": "https://www.grid.ac/institutes/grid.461861.c", 
          "name": [
            "BPMP, CNRS, INRA, SupAgro, Univ. Montpellier, Montpellier, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Herbert", 
        "givenName": "L\u00e9o", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Biochemistry and Plant Molecular Physiology", 
          "id": "https://www.grid.ac/institutes/grid.461861.c", 
          "name": [
            "BPMP, CNRS, INRA, SupAgro, Univ. Montpellier, Montpellier, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "S\u00e9r\u00e9", 
        "givenName": "David", 
        "id": "sg:person.010711404036.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010711404036.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut de Biologie de l'\u00c9cole Normale Sup\u00e9rieure", 
          "id": "https://www.grid.ac/institutes/grid.462036.5", 
          "name": [
            "Institut de Biologie de l\u2019Ecole Normale Sup\u00e9rieure, CNRS UMR8197, INSERM U1024, ENS, 46 rue d\u2019Ulm, 75005, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Caillieux", 
        "givenName": "Erwann", 
        "id": "sg:person.01244045476.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01244045476.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Biochemistry and Plant Molecular Physiology", 
          "id": "https://www.grid.ac/institutes/grid.461861.c", 
          "name": [
            "BPMP, CNRS, INRA, SupAgro, Univ. Montpellier, Montpellier, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Boucherez", 
        "givenName": "Jossia", 
        "id": "sg:person.01011764737.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011764737.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Biochemistry and Plant Molecular Physiology", 
          "id": "https://www.grid.ac/institutes/grid.461861.c", 
          "name": [
            "BPMP, CNRS, INRA, SupAgro, Univ. Montpellier, Montpellier, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fizames", 
        "givenName": "C\u00e9cile", 
        "id": "sg:person.01272635267.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272635267.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Laboratoire de Reproduction et D\u00e9veloppement des Plantes", 
          "id": "https://www.grid.ac/institutes/grid.462634.1", 
          "name": [
            "Institut de Biologie de l\u2019Ecole Normale Sup\u00e9rieure, CNRS UMR8197, INSERM U1024, ENS, 46 rue d\u2019Ulm, 75005, Paris, France", 
            "Laboratoire Reproduction et D\u00e9veloppement des Plantes, Univ Lyon, ENS de Lyon, UCB Lyon 1, CNRS, INRA, F-69342, Lyon, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Roudier", 
        "givenName": "Fran\u00e7ois", 
        "id": "sg:person.0631026676.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631026676.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Biochemistry and Plant Molecular Physiology", 
          "id": "https://www.grid.ac/institutes/grid.461861.c", 
          "name": [
            "BPMP, CNRS, INRA, SupAgro, Univ. Montpellier, Montpellier, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gojon", 
        "givenName": "Alain", 
        "id": "sg:person.01212750737.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01212750737.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Biochemistry and Plant Molecular Physiology", 
          "id": "https://www.grid.ac/institutes/grid.461861.c", 
          "name": [
            "BPMP, CNRS, INRA, SupAgro, Univ. Montpellier, Montpellier, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Martin", 
        "givenName": "Antoine", 
        "id": "sg:person.01041662464.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01041662464.05"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1105/tpc.111.087866", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004234620"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.devcel.2010.05.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009684083"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/tpj.12626", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011944919"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pgen.1005771", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012195074"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/386044a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014093586", 
          "https://doi.org/10.1038/386044a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev-arplant-043014-115627", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014538524"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1104/pp.110.157354", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015499750"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pgen.0030086", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016523052"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0158936", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017359770"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-313x.2010.04428.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019234436"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1242/dev.01400", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019374199"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1017863108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020248667"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pgen.1002014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022096799"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/emboj.2011.103", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022242688"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1105/tpc.15.00744", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023005780"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0014-5793(01)02096-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023291083"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1024899808018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025588290", 
          "https://doi.org/10.1023/a:1024899808018"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/sj.embor.7400760", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026035534"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1105/tpc.111.087809", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026876413"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature10241", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027524172", 
          "https://doi.org/10.1038/nature10241"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1105/tpc.111.083352", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027774282"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pgen.1002040", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029260729"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cub.2014.06.047", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029449429"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1503100112", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029989107"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature09784", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030505833", 
          "https://doi.org/10.1038/nature09784"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1231382", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035753092"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1104/pp.15.01335", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036076949"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00425-004-1266-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036319277", 
          "https://doi.org/10.1007/s00425-004-1266-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-3040.2007.01712.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039209550"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1104/pp.127.1.262", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039862721"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11104-013-1645-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040156615", 
          "https://doi.org/10.1007/s11104-013-1645-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1105/tpc.114.124578", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049009211"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nsmb1283", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049951834", 
          "https://doi.org/10.1038/nsmb1283"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cub.2008.11.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051701336"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1074950", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062446827"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jxb/erx062", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083933135"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-12", 
    "datePublishedReg": "2018-12-01", 
    "description": "PRC2 is a major regulator of gene expression in eukaryotes. It catalyzes the repressive chromatin mark H3K27me3, which leads to very low expression of target genes. NRT2.1, which encodes a key root nitrate transporter in Arabidopsis, is targeted by H3K27me3, but the function of PRC2 on NRT2.1 remains unclear. Here, we demonstrate that PRC2 directly targets and down-regulates NRT2.1, but in a context of very high transcription, in nutritional conditions where this gene is one of the most highly expressed genes in the transcriptome. Indeed, the mutation of CLF, which encodes a PRC2 subunit, leads to a loss of H3K27me3 at NRT2.1 and results, exclusively under permissive conditions for NRT2.1, in a further increase in NRT2.1 expression, and specifically in tissues where NRT2.1 is normally expressed. Therefore, our data indicates that PRC2 tempers the hyperactivity of NRT2.1 in a context of very strong transcription. This reveals an original function of PRC2 in the control of the expression of a highly expressed gene in Arabidopsis.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/s41598-018-26349-w", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.4519815", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1045337", 
        "issn": [
          "2045-2322"
        ], 
        "name": "Scientific Reports", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "8"
      }
    ], 
    "name": "Polycomb Repressive Complex 2 attenuates the very high expression of the Arabidopsis gene NRT2.1", 
    "pagination": "7905", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "1da98a7f2a524b105a02bbb02906d2bc8a9936296b73b41ee672a95be6fef37d"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "29784958"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101563288"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s41598-018-26349-w"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1103996504"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s41598-018-26349-w", 
      "https://app.dimensions.ai/details/publication/pub.1103996504"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T16:00", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8664_00000571.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/s41598-018-26349-w"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-26349-w'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-26349-w'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-26349-w'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-26349-w'


 

This table displays all metadata directly associated to this object as RDF triples.

247 TRIPLES      21 PREDICATES      65 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s41598-018-26349-w schema:about anzsrc-for:06
2 anzsrc-for:0604
3 schema:author N1095d319f16044acb4d107746909ef3f
4 schema:citation sg:pub.10.1007/s00425-004-1266-x
5 sg:pub.10.1007/s11104-013-1645-9
6 sg:pub.10.1023/a:1024899808018
7 sg:pub.10.1038/386044a0
8 sg:pub.10.1038/nature09784
9 sg:pub.10.1038/nature10241
10 sg:pub.10.1038/nsmb1283
11 https://doi.org/10.1016/j.cub.2008.11.019
12 https://doi.org/10.1016/j.cub.2014.06.047
13 https://doi.org/10.1016/j.devcel.2010.05.013
14 https://doi.org/10.1016/s0014-5793(01)02096-8
15 https://doi.org/10.1038/emboj.2011.103
16 https://doi.org/10.1038/sj.embor.7400760
17 https://doi.org/10.1073/pnas.1017863108
18 https://doi.org/10.1073/pnas.1503100112
19 https://doi.org/10.1093/jxb/erx062
20 https://doi.org/10.1104/pp.110.157354
21 https://doi.org/10.1104/pp.127.1.262
22 https://doi.org/10.1104/pp.15.01335
23 https://doi.org/10.1105/tpc.111.083352
24 https://doi.org/10.1105/tpc.111.087809
25 https://doi.org/10.1105/tpc.111.087866
26 https://doi.org/10.1105/tpc.114.124578
27 https://doi.org/10.1105/tpc.15.00744
28 https://doi.org/10.1111/j.1365-3040.2007.01712.x
29 https://doi.org/10.1111/j.1365-313x.2010.04428.x
30 https://doi.org/10.1111/tpj.12626
31 https://doi.org/10.1126/science.1074950
32 https://doi.org/10.1126/science.1231382
33 https://doi.org/10.1146/annurev-arplant-043014-115627
34 https://doi.org/10.1242/dev.01400
35 https://doi.org/10.1371/journal.pgen.0030086
36 https://doi.org/10.1371/journal.pgen.1002014
37 https://doi.org/10.1371/journal.pgen.1002040
38 https://doi.org/10.1371/journal.pgen.1005771
39 https://doi.org/10.1371/journal.pone.0158936
40 schema:datePublished 2018-12
41 schema:datePublishedReg 2018-12-01
42 schema:description PRC2 is a major regulator of gene expression in eukaryotes. It catalyzes the repressive chromatin mark H3K27me3, which leads to very low expression of target genes. NRT2.1, which encodes a key root nitrate transporter in Arabidopsis, is targeted by H3K27me3, but the function of PRC2 on NRT2.1 remains unclear. Here, we demonstrate that PRC2 directly targets and down-regulates NRT2.1, but in a context of very high transcription, in nutritional conditions where this gene is one of the most highly expressed genes in the transcriptome. Indeed, the mutation of CLF, which encodes a PRC2 subunit, leads to a loss of H3K27me3 at NRT2.1 and results, exclusively under permissive conditions for NRT2.1, in a further increase in NRT2.1 expression, and specifically in tissues where NRT2.1 is normally expressed. Therefore, our data indicates that PRC2 tempers the hyperactivity of NRT2.1 in a context of very strong transcription. This reveals an original function of PRC2 in the control of the expression of a highly expressed gene in Arabidopsis.
43 schema:genre research_article
44 schema:inLanguage en
45 schema:isAccessibleForFree true
46 schema:isPartOf N2019373aa21c401cb4f57cdc3b4ccce9
47 Nd73a2a05fee64d13820e2171c6b75e1f
48 sg:journal.1045337
49 schema:name Polycomb Repressive Complex 2 attenuates the very high expression of the Arabidopsis gene NRT2.1
50 schema:pagination 7905
51 schema:productId N4b22ba44c55b47a3aec7cf66bb85c5e4
52 N6297e69fb19d453ba238320bca32d673
53 N799354c7acbd4217830eda329ccbab66
54 N805603108db34de298eb8f8873be5608
55 Ne11e9120c2ab44feb45e81053eff2b15
56 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103996504
57 https://doi.org/10.1038/s41598-018-26349-w
58 schema:sdDatePublished 2019-04-10T16:00
59 schema:sdLicense https://scigraph.springernature.com/explorer/license/
60 schema:sdPublisher Nf74c8347d5aa41b0bd6d887bad1ac6ba
61 schema:url https://www.nature.com/articles/s41598-018-26349-w
62 sgo:license sg:explorer/license/
63 sgo:sdDataset articles
64 rdf:type schema:ScholarlyArticle
65 N1095d319f16044acb4d107746909ef3f rdf:first sg:person.010544441233.78
66 rdf:rest Nefc6f658286447d8a302783b7175dc60
67 N2019373aa21c401cb4f57cdc3b4ccce9 schema:issueNumber 1
68 rdf:type schema:PublicationIssue
69 N264dbef7b42f42b4a11dbd8a632ee60b rdf:first sg:person.0631026676.23
70 rdf:rest N4128690d25b947458990e2ad4c23f5a2
71 N3b30bd16be76409c9665acbeb7926f38 rdf:first sg:person.010711404036.61
72 rdf:rest N9b82af907afe4c33b78d0726e343e4ad
73 N4128690d25b947458990e2ad4c23f5a2 rdf:first sg:person.01212750737.09
74 rdf:rest Ndb0c9762333041a2b97365cb353ee784
75 N4b22ba44c55b47a3aec7cf66bb85c5e4 schema:name pubmed_id
76 schema:value 29784958
77 rdf:type schema:PropertyValue
78 N6297e69fb19d453ba238320bca32d673 schema:name readcube_id
79 schema:value 1da98a7f2a524b105a02bbb02906d2bc8a9936296b73b41ee672a95be6fef37d
80 rdf:type schema:PropertyValue
81 N6571628800614d21a7bc264946c7ba5f schema:affiliation https://www.grid.ac/institutes/grid.461861.c
82 schema:familyName Herbert
83 schema:givenName Léo
84 rdf:type schema:Person
85 N799354c7acbd4217830eda329ccbab66 schema:name nlm_unique_id
86 schema:value 101563288
87 rdf:type schema:PropertyValue
88 N805603108db34de298eb8f8873be5608 schema:name dimensions_id
89 schema:value pub.1103996504
90 rdf:type schema:PropertyValue
91 N9b82af907afe4c33b78d0726e343e4ad rdf:first sg:person.01244045476.63
92 rdf:rest Ne8765b79c84e4ddaaa9300ff92abab59
93 Nd73a2a05fee64d13820e2171c6b75e1f schema:volumeNumber 8
94 rdf:type schema:PublicationVolume
95 Ndb0c9762333041a2b97365cb353ee784 rdf:first sg:person.01041662464.05
96 rdf:rest rdf:nil
97 Ne11e9120c2ab44feb45e81053eff2b15 schema:name doi
98 schema:value 10.1038/s41598-018-26349-w
99 rdf:type schema:PropertyValue
100 Ne8765b79c84e4ddaaa9300ff92abab59 rdf:first sg:person.01011764737.13
101 rdf:rest Nec07ab39074941a282c4204191f55b4d
102 Nec07ab39074941a282c4204191f55b4d rdf:first sg:person.01272635267.23
103 rdf:rest N264dbef7b42f42b4a11dbd8a632ee60b
104 Nefc6f658286447d8a302783b7175dc60 rdf:first N6571628800614d21a7bc264946c7ba5f
105 rdf:rest N3b30bd16be76409c9665acbeb7926f38
106 Nf74c8347d5aa41b0bd6d887bad1ac6ba schema:name Springer Nature - SN SciGraph project
107 rdf:type schema:Organization
108 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
109 schema:name Biological Sciences
110 rdf:type schema:DefinedTerm
111 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
112 schema:name Genetics
113 rdf:type schema:DefinedTerm
114 sg:grant.4519815 http://pending.schema.org/fundedItem sg:pub.10.1038/s41598-018-26349-w
115 rdf:type schema:MonetaryGrant
116 sg:journal.1045337 schema:issn 2045-2322
117 schema:name Scientific Reports
118 rdf:type schema:Periodical
119 sg:person.01011764737.13 schema:affiliation https://www.grid.ac/institutes/grid.461861.c
120 schema:familyName Boucherez
121 schema:givenName Jossia
122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011764737.13
123 rdf:type schema:Person
124 sg:person.01041662464.05 schema:affiliation https://www.grid.ac/institutes/grid.461861.c
125 schema:familyName Martin
126 schema:givenName Antoine
127 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01041662464.05
128 rdf:type schema:Person
129 sg:person.010544441233.78 schema:affiliation https://www.grid.ac/institutes/grid.461861.c
130 schema:familyName Bellegarde
131 schema:givenName Fanny
132 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010544441233.78
133 rdf:type schema:Person
134 sg:person.010711404036.61 schema:affiliation https://www.grid.ac/institutes/grid.461861.c
135 schema:familyName Séré
136 schema:givenName David
137 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010711404036.61
138 rdf:type schema:Person
139 sg:person.01212750737.09 schema:affiliation https://www.grid.ac/institutes/grid.461861.c
140 schema:familyName Gojon
141 schema:givenName Alain
142 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01212750737.09
143 rdf:type schema:Person
144 sg:person.01244045476.63 schema:affiliation https://www.grid.ac/institutes/grid.462036.5
145 schema:familyName Caillieux
146 schema:givenName Erwann
147 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01244045476.63
148 rdf:type schema:Person
149 sg:person.01272635267.23 schema:affiliation https://www.grid.ac/institutes/grid.461861.c
150 schema:familyName Fizames
151 schema:givenName Cécile
152 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01272635267.23
153 rdf:type schema:Person
154 sg:person.0631026676.23 schema:affiliation https://www.grid.ac/institutes/grid.462634.1
155 schema:familyName Roudier
156 schema:givenName François
157 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631026676.23
158 rdf:type schema:Person
159 sg:pub.10.1007/s00425-004-1266-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036319277
160 https://doi.org/10.1007/s00425-004-1266-x
161 rdf:type schema:CreativeWork
162 sg:pub.10.1007/s11104-013-1645-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040156615
163 https://doi.org/10.1007/s11104-013-1645-9
164 rdf:type schema:CreativeWork
165 sg:pub.10.1023/a:1024899808018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025588290
166 https://doi.org/10.1023/a:1024899808018
167 rdf:type schema:CreativeWork
168 sg:pub.10.1038/386044a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014093586
169 https://doi.org/10.1038/386044a0
170 rdf:type schema:CreativeWork
171 sg:pub.10.1038/nature09784 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030505833
172 https://doi.org/10.1038/nature09784
173 rdf:type schema:CreativeWork
174 sg:pub.10.1038/nature10241 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027524172
175 https://doi.org/10.1038/nature10241
176 rdf:type schema:CreativeWork
177 sg:pub.10.1038/nsmb1283 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049951834
178 https://doi.org/10.1038/nsmb1283
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1016/j.cub.2008.11.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051701336
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1016/j.cub.2014.06.047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029449429
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1016/j.devcel.2010.05.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009684083
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1016/s0014-5793(01)02096-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023291083
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1038/emboj.2011.103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022242688
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1038/sj.embor.7400760 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026035534
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1073/pnas.1017863108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020248667
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1073/pnas.1503100112 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029989107
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1093/jxb/erx062 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083933135
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1104/pp.110.157354 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015499750
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1104/pp.127.1.262 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039862721
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1104/pp.15.01335 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036076949
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1105/tpc.111.083352 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027774282
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1105/tpc.111.087809 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026876413
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1105/tpc.111.087866 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004234620
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1105/tpc.114.124578 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049009211
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1105/tpc.15.00744 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023005780
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1111/j.1365-3040.2007.01712.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1039209550
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1111/j.1365-313x.2010.04428.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1019234436
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1111/tpj.12626 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011944919
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1126/science.1074950 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062446827
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1126/science.1231382 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035753092
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1146/annurev-arplant-043014-115627 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014538524
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1242/dev.01400 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019374199
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1371/journal.pgen.0030086 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016523052
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1371/journal.pgen.1002014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022096799
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1371/journal.pgen.1002040 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029260729
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1371/journal.pgen.1005771 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012195074
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1371/journal.pone.0158936 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017359770
237 rdf:type schema:CreativeWork
238 https://www.grid.ac/institutes/grid.461861.c schema:alternateName Biochemistry and Plant Molecular Physiology
239 schema:name BPMP, CNRS, INRA, SupAgro, Univ. Montpellier, Montpellier, France
240 rdf:type schema:Organization
241 https://www.grid.ac/institutes/grid.462036.5 schema:alternateName Institut de Biologie de l'École Normale Supérieure
242 schema:name Institut de Biologie de l’Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, ENS, 46 rue d’Ulm, 75005, Paris, France
243 rdf:type schema:Organization
244 https://www.grid.ac/institutes/grid.462634.1 schema:alternateName Laboratoire de Reproduction et Développement des Plantes
245 schema:name Institut de Biologie de l’Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, ENS, 46 rue d’Ulm, 75005, Paris, France
246 Laboratoire Reproduction et Développement des Plantes, Univ Lyon, ENS de Lyon, UCB Lyon 1, CNRS, INRA, F-69342, Lyon, France
247 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...