Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-05-02

AUTHORS

Biao Wang, Lingbo Kong, Ziqi Zhu, Wenjie Gao, Hua Guo, Xiaodong Wang, Hui Li, Qinpeng Zhao, Haiping Zhang, Dingjun Hao

ABSTRACT

Recurrent complex spinal tuberculosis accompanied by sinus tract formation is one of the most common and complex types of recurrent tuberculosis. To date, only very few studies have reported the strategies and effectiveness of surgical treatments on postoperative recurrent spinal tuberculosis accompanied by sinus tract formation. In this study, 21 recurrent patients out of 87 patients with complex spinal tuberculosis were reviewed. The data of the patients, including age, gender, existence of drug-resistant mycobacterium tuberculosis, postoperative standard chemotherapy, completeness of lesion debridement, reconstruction of the spinal stability, nutritional status, accompaniment by tuberculosis in other regions, timing of the operations, and areas of the lesions, were collected for single- and multiple-factor analyses. The clinical outcomes were evaluated by long-term follow-ups. The results showed that 7 factors were significantly associated with postoperative recurrence of complex spinal tuberculosis accompanied by sinus tract formation. This suggested that when we treat complex spinal tuberculosis, we should pay more attention to these seven indicators to avoid postoperative recurrence, and our clinical outcomes suggested that it is difficult to treat recurrent complicated spinal tuberculosis combined with sinus tract formation. The key for successful surgical treatment includes effective chemotherapy, radical debridement and proper reconstruction of spinal stability. More... »

PAGES

6933

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41598-018-25142-z

DOI

http://dx.doi.org/10.1038/s41598-018-25142-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1103695397

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29720686


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