Ontology type: schema:ScholarlyArticle Open Access: True
2018-12
AUTHORSJoan Martí-Fàbregas, Santiago Medrano-Martorell, Elisa Merino, Luis Prats-Sánchez, Rebeca Marín, Raquel Delgado-Mederos, Pol Camps-Renom, Alejandro Martínez-Domeño, Manuel Gómez-Choco, Lidia Lara, Ignacio Casado-Naranjo, David Cánovas, Maria José Torres, Marimar Freijo, Ana Calleja, Yolanda Bravo, Dolores Cocho, Ana Rodríguez-Campello, Beatriz Zandio, Blanca Fuentes, Alicia de Felipe, Laura Llull, José Maestre, María Hernández, Moisès Garcés, Ana Maria De Arce-Borda, Ernest Palomeras, Manuel Rodríguez-Yáñez, Inma Díaz-Maroto, Marta Serrano, Jéssica Fernández-Domínguez, Jordi Sanahuja, Francisco Purroy, Marialuisa Zedde, Jordi Delgado-Mengual, Ignasi Gich
ABSTRACTWe investigated whether pre-treatment with statins is associated with surrogate markers of amyloid and hypertensive angiopathies in patients who need to start long-term oral anticoagulation therapy. A prospective multicenter study of patients naive for oral anticoagulants, who had an acute cardioembolic stroke. MRI was performed at admission to evaluate microbleeds, leukoaraiosis and superficial siderosis. We collected data on the specific statin compound, the dose and the statin intensity. We performed bivariate analyses and a logistic regression to investigate variables associated with microbleeds. We studied 470 patients (age 77.5 ± 6.4 years, 43.7% were men), and 193 (41.1%) of them received prior treatment with a statin. Microbleeds were detected in 140 (29.8%), leukoaraiosis in 388 (82.5%) and superficial siderosis in 20 (4.3%) patients. The presence of microbleeds, leukoaraiosis or superficial siderosis was not related to pre-treatment with statins. Microbleeds were more frequent in patients with prior intracerebral hemorrhage (OR 9.7, 95% CI 1.06-90.9) and in those pre-treated antiplatelets (OR 1.66, 95% CI 1.09-2.53). Prior treatment with statins was not associated with markers of bleeding-prone cerebral angiopathies in patients with cardioembolic stroke. Therefore, previous statin treatment should not influence the decision to initiate or withhold oral anticoagulation if these neuroimaging markers are detected. More... »
PAGES1492
http://scigraph.springernature.com/pub.10.1038/s41598-018-20055-3
DOIhttp://dx.doi.org/10.1038/s41598-018-20055-3
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1100512305
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/29367736
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Hospital de Sant Pau",
"id": "https://www.grid.ac/institutes/grid.413396.a",
"name": [
"Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute, Barcelona, Spain"
],
"type": "Organization"
},
"familyName": "Mart\u00ed-F\u00e0bregas",
"givenName": "Joan",
"id": "sg:person.01350133566.08",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350133566.08"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Parc de Salut",
"id": "https://www.grid.ac/institutes/grid.418476.8",
"name": [
"Department of Radiology, Hospital del Mar- Parc de Salut Mar, Barcelona, Spain"
],
"type": "Organization"
},
"familyName": "Medrano-Martorell",
"givenName": "Santiago",
"id": "sg:person.0611104506.97",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0611104506.97"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital Universitari Germans Trias i Pujol",
"id": "https://www.grid.ac/institutes/grid.411438.b",
"name": [
"Hospital Germans Trias i Pujol, Unitat RM IDI, Badalona, Spain"
],
"type": "Organization"
},
"familyName": "Merino",
"givenName": "Elisa",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital de Sant Pau",
"id": "https://www.grid.ac/institutes/grid.413396.a",
"name": [
"Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute, Barcelona, Spain"
],
"type": "Organization"
},
"familyName": "Prats-S\u00e1nchez",
"givenName": "Luis",
"id": "sg:person.01264700125.49",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264700125.49"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital de Sant Pau",
"id": "https://www.grid.ac/institutes/grid.413396.a",
"name": [
"Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute, Barcelona, Spain"
],
"type": "Organization"
},
"familyName": "Mar\u00edn",
"givenName": "Rebeca",
"id": "sg:person.0664332147.09",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0664332147.09"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital de Sant Pau",
"id": "https://www.grid.ac/institutes/grid.413396.a",
"name": [
"Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute, Barcelona, Spain"
],
"type": "Organization"
},
"familyName": "Delgado-Mederos",
"givenName": "Raquel",
"id": "sg:person.01341623047.45",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341623047.45"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital de Sant Pau",
"id": "https://www.grid.ac/institutes/grid.413396.a",
"name": [
"Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute, Barcelona, Spain"
],
"type": "Organization"
},
"familyName": "Camps-Renom",
"givenName": "Pol",
"id": "sg:person.0725754546.11",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0725754546.11"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital de Sant Pau",
"id": "https://www.grid.ac/institutes/grid.413396.a",
"name": [
"Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute, Barcelona, Spain"
],
"type": "Organization"
},
"familyName": "Mart\u00ednez-Dome\u00f1o",
"givenName": "Alejandro",
"id": "sg:person.01224022331.28",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224022331.28"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital de Sant Joan Desp\u00ed Mois\u00e8s Broggi",
"id": "https://www.grid.ac/institutes/grid.490130.f",
"name": [
"Department of Neurology, Hospital de Sant Joan Desp\u00ed Moises Broggi, Sant Joan Desp\u00ed, Spain"
],
"type": "Organization"
},
"familyName": "G\u00f3mez-Choco",
"givenName": "Manuel",
"id": "sg:person.01062574505.43",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062574505.43"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital de Le\u00f3n",
"id": "https://www.grid.ac/institutes/grid.411969.2",
"name": [
"Department of Neurology, Hospital de Le\u00f3n, Le\u00f3n, Spain"
],
"type": "Organization"
},
"familyName": "Lara",
"givenName": "Lidia",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital San Pedro de Alc\u00e1ntara",
"id": "https://www.grid.ac/institutes/grid.413393.f",
"name": [
"Department of Neurology, Hospital San Pedro de Alc\u00e1ntara, C\u00e1ceres, Spain"
],
"type": "Organization"
},
"familyName": "Casado-Naranjo",
"givenName": "Ignacio",
"id": "sg:person.01020346143.43",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020346143.43"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital de Sabadell",
"id": "https://www.grid.ac/institutes/grid.414560.2",
"name": [
"Department of Neurology, Hospital Parc Taul\u00ed, Sabadell, Spain"
],
"type": "Organization"
},
"familyName": "C\u00e1novas",
"givenName": "David",
"id": "sg:person.0740514577.89",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0740514577.89"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital Universitario Son Espases",
"id": "https://www.grid.ac/institutes/grid.411164.7",
"name": [
"Department of Neurology, Hospital Son Espases, Palma de Mallorca, Spain"
],
"type": "Organization"
},
"familyName": "Torres",
"givenName": "Maria Jos\u00e9",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital de Basurto",
"id": "https://www.grid.ac/institutes/grid.414269.c",
"name": [
"Department of Neurology, Hospital de Basurto, Bilbao, Spain"
],
"type": "Organization"
},
"familyName": "Freijo",
"givenName": "Marimar",
"id": "sg:person.016365147767.85",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016365147767.85"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Department of Neurology, Hospital de Valladolid, Valladolid, Spain"
],
"type": "Organization"
},
"familyName": "Calleja",
"givenName": "Ana",
"type": "Person"
},
{
"affiliation": {
"name": [
"Department of Neurology, Hospital de Burgos, Burgos, Spain"
],
"type": "Organization"
},
"familyName": "Bravo",
"givenName": "Yolanda",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital General de Granollers",
"id": "https://www.grid.ac/institutes/grid.414740.2",
"name": [
"Department of Neurology, Hospital de Granollers, Granollers, Spain"
],
"type": "Organization"
},
"familyName": "Cocho",
"givenName": "Dolores",
"id": "sg:person.0607560173.55",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0607560173.55"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital Del Mar",
"id": "https://www.grid.ac/institutes/grid.411142.3",
"name": [
"Department of Neurology, Hospital del Mar, Barcelona, Spain"
],
"type": "Organization"
},
"familyName": "Rodr\u00edguez-Campello",
"givenName": "Ana",
"id": "sg:person.01030070044.53",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030070044.53"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Clinica Universidad de Navarra",
"id": "https://www.grid.ac/institutes/grid.411730.0",
"name": [
"Department of Neurology, Hospital de Navarra, Pamplona, Spain"
],
"type": "Organization"
},
"familyName": "Zandio",
"givenName": "Beatriz",
"id": "sg:person.01215644363.59",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01215644363.59"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital Universitario La Paz",
"id": "https://www.grid.ac/institutes/grid.81821.32",
"name": [
"Department of Neurology, Hospital Universitario La Paz, Instituto de Investigaci\u00f3n IdiPaz, Madrid, Spain"
],
"type": "Organization"
},
"familyName": "Fuentes",
"givenName": "Blanca",
"id": "sg:person.0637733255.08",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637733255.08"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital Universitario Ram\u00f3n y Cajal",
"id": "https://www.grid.ac/institutes/grid.411347.4",
"name": [
"Department of Neurology, Hospital Ram\u00f3n y Cajal, Madrid, Spain"
],
"type": "Organization"
},
"familyName": "de Felipe",
"givenName": "Alicia",
"id": "sg:person.01041061257.30",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01041061257.30"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital Clinic of Barcelona",
"id": "https://www.grid.ac/institutes/grid.410458.c",
"name": [
"Department of Neurology, Hospital Cl\u00ednic, Barcelona, Spain"
],
"type": "Organization"
},
"familyName": "Llull",
"givenName": "Laura",
"id": "sg:person.01010763140.98",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01010763140.98"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital Universitario Virgen de las Nieves",
"id": "https://www.grid.ac/institutes/grid.411380.f",
"name": [
"Department of Neurology, Hospital Virgen de las Nieves, Granada, Spain"
],
"type": "Organization"
},
"familyName": "Maestre",
"givenName": "Jos\u00e9",
"id": "sg:person.01154463573.41",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154463573.41"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital Universitari Germans Trias i Pujol",
"id": "https://www.grid.ac/institutes/grid.411438.b",
"name": [
"Department of Neurology, Hospital Germans Trias i Pujol, Badalona, Spain"
],
"type": "Organization"
},
"familyName": "Hern\u00e1ndez",
"givenName": "Mar\u00eda",
"type": "Person"
},
{
"affiliation": {
"name": [
"Department of Neurology, Hospital Verge de la Cinta, Tortosa, Spain"
],
"type": "Organization"
},
"familyName": "Garc\u00e9s",
"givenName": "Mois\u00e8s",
"id": "sg:person.01145461401.35",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145461401.35"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Donostia Unibertsitate Ospitalea",
"id": "https://www.grid.ac/institutes/grid.414651.3",
"name": [
"Department of Neurology, Hospital de Donostia, Donostia, Spain"
],
"type": "Organization"
},
"familyName": "De Arce-Borda",
"givenName": "Ana Maria",
"id": "sg:person.01266023063.21",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266023063.21"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital de Matar\u00f3",
"id": "https://www.grid.ac/institutes/grid.414519.c",
"name": [
"Department of Neurology, Hospital de Matar\u00f3, Matar\u00f3, Spain"
],
"type": "Organization"
},
"familyName": "Palomeras",
"givenName": "Ernest",
"id": "sg:person.01347334107.64",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01347334107.64"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Department of Neurology, Hospital Santiago de Compostela, Santiago de Compostela, Spain"
],
"type": "Organization"
},
"familyName": "Rodr\u00edguez-Y\u00e1\u00f1ez",
"givenName": "Manuel",
"type": "Person"
},
{
"affiliation": {
"name": [
"Department of Neurology, Hospital de Albacete, Albacete, Spain"
],
"type": "Organization"
},
"familyName": "D\u00edaz-Maroto",
"givenName": "Inma",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital General de La Rioja",
"id": "https://www.grid.ac/institutes/grid.414516.3",
"name": [
"Department of Neurology, Hospital de La Rioja, Logro\u00f1o, Spain"
],
"type": "Organization"
},
"familyName": "Serrano",
"givenName": "Marta",
"type": "Person"
},
{
"affiliation": {
"name": [
"Department of Neurology, Centro M\u00e9dico Asturias, Oviedo, Spain"
],
"type": "Organization"
},
"familyName": "Fern\u00e1ndez-Dom\u00ednguez",
"givenName": "J\u00e9ssica",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital Universitari Arnau de Vilanova",
"id": "https://www.grid.ac/institutes/grid.411443.7",
"name": [
"Department of Neurology, Hospital Arnau de Vilanova, Lleida, Spain"
],
"type": "Organization"
},
"familyName": "Sanahuja",
"givenName": "Jordi",
"id": "sg:person.01322043175.26",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01322043175.26"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital Universitari Arnau de Vilanova",
"id": "https://www.grid.ac/institutes/grid.411443.7",
"name": [
"Department of Neurology, Hospital Arnau de Vilanova, Lleida, Spain"
],
"type": "Organization"
},
"familyName": "Purroy",
"givenName": "Francisco",
"id": "sg:person.01023252775.50",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023252775.50"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Department of Neurology, Arcispedale Santa Maria Nuova IRCCS, Reggio Emilia, Italy"
],
"type": "Organization"
},
"familyName": "Zedde",
"givenName": "Marialuisa",
"id": "sg:person.0672301034.02",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0672301034.02"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Autonomous University of Barcelona",
"id": "https://www.grid.ac/institutes/grid.7080.f",
"name": [
"Port d\u2019Informaci\u00f3 Cient\u00edfica, Institut de F\u00edsica d\u2019Altes Energies, Campus UAB, Cerdanyola del Vall\u00e8s, Spain"
],
"type": "Organization"
},
"familyName": "Delgado-Mengual",
"givenName": "Jordi",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Hospital de Sant Pau",
"id": "https://www.grid.ac/institutes/grid.413396.a",
"name": [
"Department of Epidemiology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute, Barcelona, Spain"
],
"type": "Organization"
},
"familyName": "Gich",
"givenName": "Ignasi",
"id": "sg:person.0746137752.39",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0746137752.39"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1056/nejmoa1500858",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000418726"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.112.657486",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001301165"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.112.657486",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001301165"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00415-011-6137-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001753459",
"https://doi.org/10.1007/s00415-011-6137-3"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.107.488791",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001875379"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.107.488791",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001875379"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1371/journal.pone.0156992",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002631689"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejmoa061894",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002835057"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.108.532473",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004646147"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.108.532473",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004646147"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/jnnp-2015-312736",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004800213"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11883-015-0526-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017866300",
"https://doi.org/10.1007/s11883-015-0526-5"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11883-015-0526-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017866300",
"https://doi.org/10.1007/s11883-015-0526-5"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/brain/awl387",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018900334"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.2165/10558450-000000000-00000",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019356425",
"https://doi.org/10.2165/10558450-000000000-00000"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.2165/10558450-000000000-00000",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019356425",
"https://doi.org/10.2165/10558450-000000000-00000"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.110.594101",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021215843"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.110.594101",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021215843"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.112.655894",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022870007"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.112.655894",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022870007"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/circulationaha.111.055269",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027230806"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0140-6736(10)61350-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028469827"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jacc.2013.11.002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031012810"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/circulationaha.112.145334",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032121496"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/circulationaha.112.145334",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032121496"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.114.004130",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032679482"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.114.004130",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032679482"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/jnnp.2009.198994",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032740731"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.112.668277",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033605849"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.112.668277",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033605849"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejmoa1501031",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035722374"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/01.str.0000127786.16612.a4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037573372"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/01.str.0000127786.16612.a4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037573372"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.pharmthera.2016.11.001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037956291"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/phar.1674",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038521539"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/brain/awv162",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039303561"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.109.572594",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043049103"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.109.572594",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043049103"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.113.002751",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043105193"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.113.002751",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043105193"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0140-6736(04)15690-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043217755"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/01.atv.0000038754.39483.cd",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046671130"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/archneurol.2010.356",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048242347"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.113.001304",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048764429"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.113.001304",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048764429"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.114.005151",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049557241"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.114.005151",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049557241"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.113.001326",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051852506"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/strokeaha.113.001326",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051852506"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/01.str.0000036092.23649.2e",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052106007"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s13311-014-0270-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053010829",
"https://doi.org/10.1007/s13311-014-0270-5"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/01.wnl.0000252799.64165.d5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064348883"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/01.wnl.0000252799.64165.d5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064348883"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/01.wnl.0000252799.64165.d5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064348883"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/01.wnl.0000296277.63350.77",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064349905"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/01.wnl.0000296277.63350.77",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064349905"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/01.wnl.0000296277.63350.77",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064349905"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/01.wnl.0000339060.11702.dd",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064350818"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/01.wnl.0000339060.11702.dd",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064350818"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1212/01.wnl.0000339060.11702.dd",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064350818"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2214/ajr.149.2.351",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1069314423"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1074454709",
"type": "CreativeWork"
}
],
"datePublished": "2018-12",
"datePublishedReg": "2018-12-01",
"description": "We investigated whether pre-treatment with statins is associated with surrogate markers of amyloid and hypertensive angiopathies in patients who need to start long-term oral anticoagulation therapy. A prospective multicenter study of patients naive for oral anticoagulants, who had an acute cardioembolic stroke. MRI was performed at admission to evaluate microbleeds, leukoaraiosis and superficial siderosis. We collected data on the specific statin compound, the dose and the statin intensity. We performed bivariate analyses and a logistic regression to investigate variables associated with microbleeds. We studied 470 patients (age 77.5\u2009\u00b1\u20096.4 years, 43.7% were men), and 193 (41.1%) of them received prior treatment with a statin. Microbleeds were detected in 140 (29.8%), leukoaraiosis in 388 (82.5%) and superficial siderosis in 20 (4.3%) patients. The presence of microbleeds, leukoaraiosis or superficial siderosis was not related to pre-treatment with statins. Microbleeds were more frequent in patients with prior intracerebral hemorrhage (OR 9.7, 95% CI 1.06-90.9) and in those pre-treated antiplatelets (OR 1.66, 95% CI 1.09-2.53). Prior treatment with statins was not associated with markers of bleeding-prone cerebral angiopathies in patients with cardioembolic stroke. Therefore, previous statin treatment should not influence the decision to initiate or withhold oral anticoagulation if these neuroimaging markers are detected.",
"genre": "research_article",
"id": "sg:pub.10.1038/s41598-018-20055-3",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isFundedItemOf": [
{
"id": "sg:grant.3725424",
"type": "MonetaryGrant"
}
],
"isPartOf": [
{
"id": "sg:journal.1045337",
"issn": [
"2045-2322"
],
"name": "Scientific Reports",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "8"
}
],
"name": "Statins do not increase Markers of Cerebral Angiopathies in patients with Cardioembolic Stroke",
"pagination": "1492",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"500d1dc17a57573ab67f594cd7cb1b9a427fa1122ae5e86fb96cf0d8b23e178c"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"29367736"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"101563288"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/s41598-018-20055-3"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1100512305"
]
}
],
"sameAs": [
"https://doi.org/10.1038/s41598-018-20055-3",
"https://app.dimensions.ai/details/publication/pub.1100512305"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T00:25",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8695_00000567.jsonl",
"type": "ScholarlyArticle",
"url": "https://www.nature.com/articles/s41598-018-20055-3"
}
]
Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-20055-3'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-20055-3'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-20055-3'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41598-018-20055-3'
This table displays all metadata directly associated to this object as RDF triples.
503 TRIPLES
21 PREDICATES
69 URIs
21 LITERALS
9 BLANK NODES