Visual field loss and vision-related quality of life in the Italian Primary Open Angle Glaucoma Study View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-12

AUTHORS

Eliana Rulli, Luciano Quaranta, Ivano Riva, Davide Poli, Lital Hollander, Fabio Galli, Andreas Katsanos, Francesco Oddone, Valter Torri, Robert N. Weinreb,

ABSTRACT

The aim of this study was to examine the relationship between visual field (VF) loss, vision-related quality of life (QoL) and glaucoma-related symptoms in a large cohort of primary open angle glaucoma (POAG) patients. POAG patients with or without VF defects or "glaucoma suspect" patients were considered eligible. QoL was assessed using the validated versions of the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) and glaucoma-related symptoms were assessed using the Glaucoma Symptom Scale (GSS). Patients were classified as having VF damage in one eye (VFD-1), both eyes (VFD-2), or neither eye (VFD-0). 3227 patients were enrolled and 2940 were eligible for the analysis. 13.4% of patients were classified in the VFD-0, 23.7% in the VFD-1, and 62.9% in the VFD-2 group. GSS visual symptoms domain (Func-4) and GSS non-visual symptoms domain (Symp-6) scores were similar for the VFD-0 and VFD-1 groups (p = 0.133 and p = 0.834 for Func-4 and Symp-6, respectively). VFD-0 group had higher scores than VFD-2 both in Func-4 (p < 0.001) and Symp-6 domains (p = 0.035). Regarding the NEI-VFQ-25, our data demonstrated that bilateral VF defects are associated with vision-related QoL deterioration, irrespective of visual acuity. More... »

PAGES

619

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41598-017-19113-z

DOI

http://dx.doi.org/10.1038/s41598-017-19113-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1100249135

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29330448


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385 https://www.grid.ac/institutes/grid.4527.4 schema:alternateName Mario Negri Institute for Pharmacological Research
386 schema:name IRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
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388 https://www.grid.ac/institutes/grid.7637.5 schema:alternateName University of Brescia
389 schema:name DMSS, University of Brescia, Brescia, Italy
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