Ontology type: schema:ScholarlyArticle Open Access: True
2017-12
AUTHORSYingqiu Li, Fan Zhao, Qiayu Wu, Mengjie Li, Yingying Zhu, Shangxin Song, Jing Zhu, Yafang Ma, He Li, Xuebin Shi, Xinglian Xu, Guanghong Zhou, Chunbao Li
ABSTRACTThe impact of dietary soybean oil, lard and fish oil on physiological responses in middle age is little studied. In this study, we investigated the changes of oxidative stress, inflammatory cytokines, telomere length, and age-related gene expression in the liver of middle-aged rats in response to the above three fat diets. Male Sprague Dawley rats (12 months old) were fed AIN-93M diets for 3 months, in which soybean oil was equivalently replaced by lard or fish oil. As compared to the lard diet, intake of fish oil diet significantly decreased body weight gain, white blood cell count, and levels of hepatic triacylglycerol, total cholesterol, fat accumulation, low-density lipoprotein, oxidative stress and inflammatory cytokines (P < 0.05), but increased telomere length (P < 0.05). On the other hand, lard diet and soybean oil diet showed great similarity in the above variables. PCR array analysis further indicated that fish oil diet significantly down-regulated gene expression related to inflammatory response, apoptosis, DNA binding, proteostasis and telomere attrition. Differentially expressed genes were enriched in the complement and coagulation cascades pathways. Such physiological and molecular responses could be due to different fatty acid composition in fish oil, lard and soybean oil. More... »
PAGES6241
http://scigraph.springernature.com/pub.10.1038/s41598-017-06506-3
DOIhttp://dx.doi.org/10.1038/s41598-017-06506-3
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1090780716
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/28740245
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1111",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Nutrition and Dietetics",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Aging",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Animals",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cytokines",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Fish Oils",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Inflammation",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Liver Diseases",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Male",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Oxidative Stress",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Rats",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Rats, Sprague-Dawley",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Telomere Homeostasis",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"name": [
"Key Laboratory of Meat Processing and Quality Control, MOE, Key Laboratory of Meat Processing, MOA, Jiangsu Innovation Center of Meat Production and Processing, Nanjing Agricultural University, 210095, Nanjing, P.R. China",
"Guangxi Vocational College of Technology and Business, 530008, Nanning, Guangxi, P.R. China"
],
"type": "Organization"
},
"familyName": "Li",
"givenName": "Yingqiu",
"id": "sg:person.014625175233.79",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014625175233.79"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Key Laboratory of Meat Processing and Quality Control, MOE, Key Laboratory of Meat Processing, MOA, Jiangsu Innovation Center of Meat Production and Processing, Nanjing Agricultural University, 210095, Nanjing, P.R. China"
],
"type": "Organization"
},
"familyName": "Zhao",
"givenName": "Fan",
"id": "sg:person.0617233553.37",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0617233553.37"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Key Laboratory of Meat Processing and Quality Control, MOE, Key Laboratory of Meat Processing, MOA, Jiangsu Innovation Center of Meat Production and Processing, Nanjing Agricultural University, 210095, Nanjing, P.R. China"
],
"type": "Organization"
},
"familyName": "Wu",
"givenName": "Qiayu",
"id": "sg:person.015306554127.17",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015306554127.17"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Key Laboratory of Meat Processing and Quality Control, MOE, Key Laboratory of Meat Processing, MOA, Jiangsu Innovation Center of Meat Production and Processing, Nanjing Agricultural University, 210095, Nanjing, P.R. China"
],
"type": "Organization"
},
"familyName": "Li",
"givenName": "Mengjie",
"id": "sg:person.01342637653.18",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342637653.18"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Key Laboratory of Meat Processing and Quality Control, MOE, Key Laboratory of Meat Processing, MOA, Jiangsu Innovation Center of Meat Production and Processing, Nanjing Agricultural University, 210095, Nanjing, P.R. China"
],
"type": "Organization"
},
"familyName": "Zhu",
"givenName": "Yingying",
"id": "sg:person.0635756371.07",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0635756371.07"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Nanjing Xiaozhuang University",
"id": "https://www.grid.ac/institutes/grid.440845.9",
"name": [
"Key Laboratory of Meat Processing and Quality Control, MOE, Key Laboratory of Meat Processing, MOA, Jiangsu Innovation Center of Meat Production and Processing, Nanjing Agricultural University, 210095, Nanjing, P.R. China",
"School of Food Science, Nanjing Xiaozhuang University, 211171, Nanjing, P.R. China"
],
"type": "Organization"
},
"familyName": "Song",
"givenName": "Shangxin",
"id": "sg:person.01317542531.50",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317542531.50"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Key Laboratory of Meat Processing and Quality Control, MOE, Key Laboratory of Meat Processing, MOA, Jiangsu Innovation Center of Meat Production and Processing, Nanjing Agricultural University, 210095, Nanjing, P.R. China"
],
"type": "Organization"
},
"familyName": "Zhu",
"givenName": "Jing",
"id": "sg:person.0653060175.34",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0653060175.34"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Key Laboratory of Meat Processing and Quality Control, MOE, Key Laboratory of Meat Processing, MOA, Jiangsu Innovation Center of Meat Production and Processing, Nanjing Agricultural University, 210095, Nanjing, P.R. China"
],
"type": "Organization"
},
"familyName": "Ma",
"givenName": "Yafang",
"id": "sg:person.014541352043.32",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014541352043.32"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Key Laboratory of Meat Processing and Quality Control, MOE, Key Laboratory of Meat Processing, MOA, Jiangsu Innovation Center of Meat Production and Processing, Nanjing Agricultural University, 210095, Nanjing, P.R. China"
],
"type": "Organization"
},
"familyName": "Li",
"givenName": "He",
"id": "sg:person.011637273233.50",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011637273233.50"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Key Laboratory of Meat Processing and Quality Control, MOE, Key Laboratory of Meat Processing, MOA, Jiangsu Innovation Center of Meat Production and Processing, Nanjing Agricultural University, 210095, Nanjing, P.R. China"
],
"type": "Organization"
},
"familyName": "Shi",
"givenName": "Xuebin",
"id": "sg:person.01020320171.36",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020320171.36"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Key Laboratory of Meat Processing and Quality Control, MOE, Key Laboratory of Meat Processing, MOA, Jiangsu Innovation Center of Meat Production and Processing, Nanjing Agricultural University, 210095, Nanjing, P.R. China"
],
"type": "Organization"
},
"familyName": "Xu",
"givenName": "Xinglian",
"id": "sg:person.0764176271.21",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0764176271.21"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Key Laboratory of Meat Processing and Quality Control, MOE, Key Laboratory of Meat Processing, MOA, Jiangsu Innovation Center of Meat Production and Processing, Nanjing Agricultural University, 210095, Nanjing, P.R. China"
],
"type": "Organization"
},
"familyName": "Zhou",
"givenName": "Guanghong",
"id": "sg:person.01261752723.94",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261752723.94"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Key Laboratory of Meat Processing and Quality Control, MOE, Key Laboratory of Meat Processing, MOA, Jiangsu Innovation Center of Meat Production and Processing, Nanjing Agricultural University, 210095, Nanjing, P.R. China"
],
"type": "Organization"
},
"familyName": "Li",
"givenName": "Chunbao",
"id": "sg:person.01337312751.35",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01337312751.35"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1038/nrendo.2013.29",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000173906",
"https://doi.org/10.1038/nrendo.2013.29"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf02536628",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000669468",
"https://doi.org/10.1007/bf02536628"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.tem.2015.08.006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000685764"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3390/nu7105433",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001844791"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1463-1326.2009.01130.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004440886"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1463-1326.2009.01130.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004440886"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/srep20036",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006782067",
"https://doi.org/10.1038/srep20036"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jnutbio.2003.12.008",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007223036"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/gerona/glu045",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009032312"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.metabol.2009.02.013",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010296311"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature07976",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010869485",
"https://doi.org/10.1038/nature07976"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature07976",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010869485",
"https://doi.org/10.1038/nature07976"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0168-8227(01)00338-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010955973"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0092-8674(02)00703-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012930185"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.cell.2007.12.018",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015281436"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.numecd.2009.12.007",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015435943"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nri3793",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016759517",
"https://doi.org/10.1038/nri3793"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1194/jlr.m200361-jlr200",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016764650"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jacl.2016.04.011",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020552129"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jacl.2016.04.011",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020552129"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jacl.2016.04.011",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020552129"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jacl.2016.04.011",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020552129"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.neuroscience.2013.11.016",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020814534"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1053/j.gastro.2016.10.019",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021797266"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jnutbio.2009.09.010",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023076157"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1194/jlr.m030700",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023457296"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/492041b",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026482451",
"https://doi.org/10.1038/492041b"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/mp.2014.70",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028509193",
"https://doi.org/10.1038/mp.2014.70"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.bbalip.2011.03.004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028779435"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.2165/00002512-199303010-00006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029627036",
"https://doi.org/10.2165/00002512-199303010-00006"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1146/annurev.psych.55.090902.141521",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031648315"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/1476-511x-8-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032127191",
"https://doi.org/10.1186/1476-511x-8-8"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/978-3-642-39495-9_20",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034483556",
"https://doi.org/10.1007/978-3-642-39495-9_20"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/epirev/mxs008",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034801166"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.plefa.2010.02.012",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035039588"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11745-999-0369-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035131177",
"https://doi.org/10.1007/s11745-999-0369-5"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s12937-016-0191-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036241212",
"https://doi.org/10.1186/s12937-016-0191-8"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s12937-016-0191-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036241212",
"https://doi.org/10.1186/s12937-016-0191-8"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1523/jneurosci.4225-04.2005",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037792880"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1152/physrev.00018.2001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038118386"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0148607111414580",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039084872"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/1480-9222-13-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039151853",
"https://doi.org/10.1186/1480-9222-13-1"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0899-9007(00)00584-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040600155"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s12937-015-0115-z",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040689466",
"https://doi.org/10.1186/s12937-015-0115-z"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0891-5849(03)00027-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041002715"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0891-5849(03)00027-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041002715"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3181/0711-mr-311",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041343916"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3181/0711-mr-311",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041343916"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.cell.2013.05.039",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041626640"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/gerona/glt157",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041969905"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1371/journal.pone.0074234",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044111828"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jhep.2013.01.006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044148506"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.neurobiolaging.2010.04.001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045600689"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1124/jpet.111.184341",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045755119"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.biocel.2011.10.007",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046527831"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1152/ajpgi.00258.2013",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048525397"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1371/journal.pone.0104083",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048934850"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/01.cir.0000038493.65177.94",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049418474"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/1476-511x-8-25",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050087202",
"https://doi.org/10.1186/1476-511x-8-25"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/b978-012757230-7/50024-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051622730"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41598-016-0001-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1056467545",
"https://doi.org/10.1038/s41598-016-0001-8"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1080/15548627.2015.1100356",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1058406632"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0022034510387794",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1063628977"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0022034510387794",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1063628977"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2174/138161209789058110",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1069167050"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.4149/gpb_2009_03_266",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1072261499"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.4161/auto.1.3.2017",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1072289423"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/ajcn/71.1.171s",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1074569729"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1152/ajpendo.2000.278.6.e1124",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1074645096"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/jn/131.1.39",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1074768362"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/jn/121.4.547",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1078036159"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/543s1a",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1084127568",
"https://doi.org/10.1038/543s1a"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature21388",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1084128532",
"https://doi.org/10.1038/nature21388"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1039/c7fo00094d",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1084743531"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1038/s41598-016-0001-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1085372625"
],
"type": "CreativeWork"
}
],
"datePublished": "2017-12",
"datePublishedReg": "2017-12-01",
"description": "The impact of dietary soybean oil, lard and fish oil on physiological responses in middle age is little studied. In this study, we investigated the changes of oxidative stress, inflammatory cytokines, telomere length, and age-related gene expression in the liver of middle-aged rats in response to the above three fat diets. Male Sprague Dawley rats (12 months old) were fed AIN-93M diets for 3 months, in which soybean oil was equivalently replaced by lard or fish oil. As compared to the lard diet, intake of fish oil diet significantly decreased body weight gain, white blood cell count, and levels of hepatic triacylglycerol, total cholesterol, fat accumulation, low-density lipoprotein, oxidative stress and inflammatory cytokines (P\u2009<\u20090.05), but increased telomere length (P\u2009<\u20090.05). On the other hand, lard diet and soybean oil diet showed great similarity in the above variables. PCR array analysis further indicated that fish oil diet significantly down-regulated gene expression related to inflammatory response, apoptosis, DNA binding, proteostasis and telomere attrition. Differentially expressed genes were enriched in the complement and coagulation cascades pathways. Such physiological and molecular responses could be due to different fatty acid composition in fish oil, lard and soybean oil.",
"genre": "research_article",
"id": "sg:pub.10.1038/s41598-017-06506-3",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1045337",
"issn": [
"2045-2322"
],
"name": "Scientific Reports",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "7"
}
],
"name": "Fish oil diet may reduce inflammatory levels in the liver of middle-aged rats",
"pagination": "6241",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"0109cce53307206031b9ec0b4dfb37ca14014878e3dc7d761c22db08fa84efa1"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"28740245"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"101563288"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/s41598-017-06506-3"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1090780716"
]
}
],
"sameAs": [
"https://doi.org/10.1038/s41598-017-06506-3",
"https://app.dimensions.ai/details/publication/pub.1090780716"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T11:04",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000352_0000000352/records_60367_00000003.jsonl",
"type": "ScholarlyArticle",
"url": "https://www.nature.com/articles/s41598-017-06506-3"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41598-017-06506-3'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41598-017-06506-3'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41598-017-06506-3'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41598-017-06506-3'
This table displays all metadata directly associated to this object as RDF triples.
438 TRIPLES
21 PREDICATES
106 URIs
32 LITERALS
20 BLANK NODES