Direct, rapid antimicrobial susceptibility test from positive blood cultures based on microscopic imaging analysis View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-12

AUTHORS

Jungil Choi, Hyun Yong Jeong, Gi Yoon Lee, Sangkwon Han, Shinhun Han, Bonghwan Jin, Taegeun Lim, Shin Kim, Dong Young Kim, Hee Chan Kim, Eui-Chong Kim, Sang Hoon Song, Taek Soo Kim, Sunghoon Kwon

ABSTRACT

For the timely treatment of patients with infections in bloodstream and cerebrospinal fluid, a rapid antimicrobial susceptibility test (AST) is urgently needed. Here, we describe a direct and rapid antimicrobial susceptibility testing (dRAST) system, which can determine the antimicrobial susceptibility of bacteria from a positive blood culture bottle (PBCB) in six hours. The positive blood culture sample is directly mixed with agarose and inoculated into a micropatterned plastic microchip with lyophilized antibiotic agents. Using microscopic detection of bacterial colony formation in agarose, the total time to result from a PBCB for dRAST was only six hours for a wide range of bacterial concentrations in PBCBs. The results from the dRAST system were consistent with the results from a standard AST, broth microdilution test. In tests of clinical isolates (n = 206) composed of 16 Gram-negative species and seven Gram-positive species, the dRAST system was accurate compared to the standard broth microdilution test, with rates of 91.11% (2613/2868) categorical agreement, 6.69% (192/2868) minor error, 2.72% (50/1837) major error and 1.45% (13/896) very major error. Thus, the dRAST system can be used to rapidly identify appropriate antimicrobial agents for the treatment of blood stream infection (BSI) and antibiotic-resistant strain infections. More... »

PAGES

1148

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41598-017-01278-2

DOI

http://dx.doi.org/10.1038/s41598-017-01278-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1085055340

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28442767


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0605", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Microbiology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anti-Bacterial Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bacteremia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blood Culture", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Meningitis, Bacterial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microbial Sensitivity Tests", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microscopy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Optical Imaging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Seoul National University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412484.f", 
          "name": [
            "QuantaMatrix Inc., Medical Innovation Center, Seoul National University Hospital, 03080, Seoul, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Choi", 
        "givenName": "Jungil", 
        "id": "sg:person.01362730047.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362730047.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Seoul National University", 
          "id": "https://www.grid.ac/institutes/grid.31501.36", 
          "name": [
            "Institutes of Entrepreneurial BioConvergence, Seoul National University, 08826, Seoul, Republic of Korea", 
            "Program of Nano Science and Technology, Graduate School of Convergence Science and Technology, Seoul National University, 08826, Seoul, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jeong", 
        "givenName": "Hyun Yong", 
        "id": "sg:person.010155603320.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010155603320.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Seoul National University", 
          "id": "https://www.grid.ac/institutes/grid.31501.36", 
          "name": [
            "Institutes of Entrepreneurial BioConvergence, Seoul National University, 08826, Seoul, Republic of Korea", 
            "Department of Electrical and Computer Engineering, Institute of Engineering Research, Seoul National University, 08826, Seoul, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lee", 
        "givenName": "Gi Yoon", 
        "id": "sg:person.011451515613.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011451515613.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Seoul National University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412484.f", 
          "name": [
            "QuantaMatrix Inc., Medical Innovation Center, Seoul National University Hospital, 03080, Seoul, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Han", 
        "givenName": "Sangkwon", 
        "id": "sg:person.01326273120.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01326273120.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Seoul National University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412484.f", 
          "name": [
            "QuantaMatrix Inc., Medical Innovation Center, Seoul National University Hospital, 03080, Seoul, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Han", 
        "givenName": "Shinhun", 
        "id": "sg:person.013044456613.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013044456613.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Seoul National University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412484.f", 
          "name": [
            "QuantaMatrix Inc., Medical Innovation Center, Seoul National University Hospital, 03080, Seoul, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jin", 
        "givenName": "Bonghwan", 
        "id": "sg:person.01054767010.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054767010.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Seoul National University", 
          "id": "https://www.grid.ac/institutes/grid.31501.36", 
          "name": [
            "QuantaMatrix Inc., Medical Innovation Center, Seoul National University Hospital, 03080, Seoul, Republic of Korea", 
            "Institutes of Entrepreneurial BioConvergence, Seoul National University, 08826, Seoul, Republic of Korea", 
            "Department of Electrical and Computer Engineering, Institute of Engineering Research, Seoul National University, 08826, Seoul, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lim", 
        "givenName": "Taegeun", 
        "id": "sg:person.011203640720.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011203640720.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Seoul National University", 
          "id": "https://www.grid.ac/institutes/grid.31501.36", 
          "name": [
            "Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University, 03080, Seoul, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Shin", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Seoul National University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412484.f", 
          "name": [
            "QuantaMatrix Inc., Medical Innovation Center, Seoul National University Hospital, 03080, Seoul, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Dong Young", 
        "id": "sg:person.01315544674.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01315544674.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Seoul National University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412484.f", 
          "name": [
            "Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University, 03080, Seoul, Republic of Korea", 
            "Department of Biomedical Engineering, Seoul National University College of Medicine, 03080, Seoul, Republic of Korea", 
            "Department of Biomedical Engineering, Seoul National University Hospital, 03080, Seoul, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Hee Chan", 
        "id": "sg:person.01100214455.87", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100214455.87"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Seoul National University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412484.f", 
          "name": [
            "Department of Laboratory Medicine, Seoul National University Hospital, 03080, Seoul, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Eui-Chong", 
        "id": "sg:person.01346342474.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01346342474.77"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Seoul National University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412484.f", 
          "name": [
            "Department of Laboratory Medicine, Seoul National University Hospital, 03080, Seoul, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Song", 
        "givenName": "Sang Hoon", 
        "id": "sg:person.01134047117.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01134047117.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Seoul National University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412484.f", 
          "name": [
            "Department of Laboratory Medicine, Seoul National University Hospital, 03080, Seoul, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Taek Soo", 
        "id": "sg:person.0754535343.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0754535343.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Seoul National University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412484.f", 
          "name": [
            "QuantaMatrix Inc., Medical Innovation Center, Seoul National University Hospital, 03080, Seoul, Republic of Korea", 
            "Institutes of Entrepreneurial BioConvergence, Seoul National University, 08826, Seoul, Republic of Korea", 
            "Program of Nano Science and Technology, Graduate School of Convergence Science and Technology, Seoul National University, 08826, Seoul, Republic of Korea", 
            "Department of Electrical and Computer Engineering, Institute of Engineering Research, Seoul National University, 08826, Seoul, Republic of Korea", 
            "Seoul National University Hospital Biomedical Research Institute, Seoul National University Hospital, 03080, Seoul, Republic of Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kwon", 
        "givenName": "Sunghoon", 
        "id": "sg:person.010646021163.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010646021163.16"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1039/c2lc40531h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000298710"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.micro.55.1.165", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001038130"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.cellbio.21.012704.131001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001236971"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc4995", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002319592", 
          "https://doi.org/10.1186/cc4995"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc4995", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002319592", 
          "https://doi.org/10.1186/cc4995"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jac/dkn554", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008573006"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-200107000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010433290"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-200107000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010433290"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-200107000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010433290"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mimet.2013.12.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013325191"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/btu022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013849143"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.ccm.0000217961.75225.e9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015684145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.ccm.0000217961.75225.e9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015684145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.diagmicrobio.2011.09.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016771179"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c0lc00734j", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017062576"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.01831-09", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018357362"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5858/arpa.2012-0651-oa", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018735150"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/647952", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020057169"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jgar.2013.06.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023043977"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.45.12.3548-3554.2001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023644134"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.42.4.1466-1470.2004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024030687"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.05021-11", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025102900"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncomms6427", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026239375", 
          "https://doi.org/10.1038/ncomms6427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.20.5.696", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027959065"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0087870", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029383617"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c004691d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029822787"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c004691d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029822787"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm1145", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030272790", 
          "https://doi.org/10.1038/nm1145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm1145", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030272790", 
          "https://doi.org/10.1038/nm1145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1553-2712.2010.00871.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031282129"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1553-2712.2010.00871.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031282129"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.36.1.223", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033368093"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.42.8.3734-3738.2004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034549538"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm0712-997", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035696227", 
          "https://doi.org/10.1038/nm0712-997"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.41.10.4751-4754.2003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036499704"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ac4004248", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039318635"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c5lc00375j", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039761973"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/cb100336p", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047005096"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.42.1.7-11.2004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048249753"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.juro.2010.09.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048607999"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/antibiotics4040455", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050103617"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10096-015-2492-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051465019", 
          "https://doi.org/10.1007/s10096-015-2492-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10096-015-2492-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051465019", 
          "https://doi.org/10.1007/s10096-015-2492-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c2lc41055a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051964050"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ac303282j", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055003778"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/scitranslmed.3009650", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062688471"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.01171-14", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062711999"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074358547", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074729513", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078897195", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080962191", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081775203", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082569890", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.40.12.2686", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083079736"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-12", 
    "datePublishedReg": "2017-12-01", 
    "description": "For the timely treatment of patients with infections in bloodstream and cerebrospinal fluid, a rapid antimicrobial susceptibility test (AST) is urgently needed. Here, we describe a direct and rapid antimicrobial susceptibility testing (dRAST) system, which can determine the antimicrobial susceptibility of bacteria from a positive blood culture bottle (PBCB) in six hours. The positive blood culture sample is directly mixed with agarose and inoculated into a micropatterned plastic microchip with lyophilized antibiotic agents. Using microscopic detection of bacterial colony formation in agarose, the total time to result from a PBCB for dRAST was only six hours for a wide range of bacterial concentrations in PBCBs. The results from the dRAST system were consistent with the results from a standard AST, broth microdilution test. In tests of clinical isolates (n\u2009=\u2009206) composed of 16 Gram-negative species and seven Gram-positive species, the dRAST system was accurate compared to the standard broth microdilution test, with rates of 91.11% (2613/2868) categorical agreement, 6.69% (192/2868) minor error, 2.72% (50/1837) major error and 1.45% (13/896) very major error. Thus, the dRAST system can be used to rapidly identify appropriate antimicrobial agents for the treatment of blood stream infection (BSI) and antibiotic-resistant strain infections.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/s41598-017-01278-2", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.7497494", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.7466677", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1045337", 
        "issn": [
          "2045-2322"
        ], 
        "name": "Scientific Reports", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "7"
      }
    ], 
    "name": "Direct, rapid antimicrobial susceptibility test from positive blood cultures based on microscopic imaging analysis", 
    "pagination": "1148", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "f4c880e881c30690f7b0f3b19b5da277fc6f8ec8ea3e123b03a31a78a7f0e8b0"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28442767"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101563288"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s41598-017-01278-2"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1085055340"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s41598-017-01278-2", 
      "https://app.dimensions.ai/details/publication/pub.1085055340"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T21:40", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8687_00000528.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/s41598-017-01278-2"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41598-017-01278-2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41598-017-01278-2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41598-017-01278-2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41598-017-01278-2'


 

This table displays all metadata directly associated to this object as RDF triples.

350 TRIPLES      21 PREDICATES      84 URIs      30 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s41598-017-01278-2 schema:about N01a2b2e6484a4a069d799af4fc07a7ed
2 N02b6be091a294e6b8c979d44808457a3
3 N06cb0008c0e1460cb3f0627ddde485ca
4 N23d4bca6cf25445ba1fc70e3e915bb34
5 N4aa3c2a83d9e4a668ea6507824b39348
6 N93150e8ef0074c63b04a0cc479624015
7 Na93be72479564f438fefac2cd2cab205
8 Ne61c6b5969da4d6089131af11739e2d2
9 Nfd11eede8e8b45ebb9e6118f0ae1c180
10 anzsrc-for:06
11 anzsrc-for:0605
12 schema:author Ne8be9c192d0543428013321a35b2a7e2
13 schema:citation sg:pub.10.1007/s10096-015-2492-9
14 sg:pub.10.1038/ncomms6427
15 sg:pub.10.1038/nm0712-997
16 sg:pub.10.1038/nm1145
17 sg:pub.10.1186/cc4995
18 https://app.dimensions.ai/details/publication/pub.1074358547
19 https://app.dimensions.ai/details/publication/pub.1074729513
20 https://app.dimensions.ai/details/publication/pub.1078897195
21 https://app.dimensions.ai/details/publication/pub.1080962191
22 https://app.dimensions.ai/details/publication/pub.1081775203
23 https://app.dimensions.ai/details/publication/pub.1082569890
24 https://doi.org/10.1016/j.diagmicrobio.2011.09.015
25 https://doi.org/10.1016/j.jgar.2013.06.005
26 https://doi.org/10.1016/j.juro.2010.09.022
27 https://doi.org/10.1016/j.mimet.2013.12.021
28 https://doi.org/10.1021/ac303282j
29 https://doi.org/10.1021/ac4004248
30 https://doi.org/10.1021/cb100336p
31 https://doi.org/10.1039/c004691d
32 https://doi.org/10.1039/c0lc00734j
33 https://doi.org/10.1039/c2lc40531h
34 https://doi.org/10.1039/c2lc41055a
35 https://doi.org/10.1039/c5lc00375j
36 https://doi.org/10.1086/647952
37 https://doi.org/10.1093/bioinformatics/btu022
38 https://doi.org/10.1093/jac/dkn554
39 https://doi.org/10.1097/00003246-200107000-00002
40 https://doi.org/10.1097/01.ccm.0000217961.75225.e9
41 https://doi.org/10.1111/j.1553-2712.2010.00871.x
42 https://doi.org/10.1126/scitranslmed.3009650
43 https://doi.org/10.1128/aac.20.5.696
44 https://doi.org/10.1128/aac.36.1.223
45 https://doi.org/10.1128/aac.40.12.2686
46 https://doi.org/10.1128/aac.45.12.3548-3554.2001
47 https://doi.org/10.1128/jcm.01171-14
48 https://doi.org/10.1128/jcm.01831-09
49 https://doi.org/10.1128/jcm.05021-11
50 https://doi.org/10.1128/jcm.41.10.4751-4754.2003
51 https://doi.org/10.1128/jcm.42.1.7-11.2004
52 https://doi.org/10.1128/jcm.42.4.1466-1470.2004
53 https://doi.org/10.1128/jcm.42.8.3734-3738.2004
54 https://doi.org/10.1146/annurev.cellbio.21.012704.131001
55 https://doi.org/10.1146/annurev.micro.55.1.165
56 https://doi.org/10.1371/journal.pone.0087870
57 https://doi.org/10.3390/antibiotics4040455
58 https://doi.org/10.5858/arpa.2012-0651-oa
59 schema:datePublished 2017-12
60 schema:datePublishedReg 2017-12-01
61 schema:description For the timely treatment of patients with infections in bloodstream and cerebrospinal fluid, a rapid antimicrobial susceptibility test (AST) is urgently needed. Here, we describe a direct and rapid antimicrobial susceptibility testing (dRAST) system, which can determine the antimicrobial susceptibility of bacteria from a positive blood culture bottle (PBCB) in six hours. The positive blood culture sample is directly mixed with agarose and inoculated into a micropatterned plastic microchip with lyophilized antibiotic agents. Using microscopic detection of bacterial colony formation in agarose, the total time to result from a PBCB for dRAST was only six hours for a wide range of bacterial concentrations in PBCBs. The results from the dRAST system were consistent with the results from a standard AST, broth microdilution test. In tests of clinical isolates (n = 206) composed of 16 Gram-negative species and seven Gram-positive species, the dRAST system was accurate compared to the standard broth microdilution test, with rates of 91.11% (2613/2868) categorical agreement, 6.69% (192/2868) minor error, 2.72% (50/1837) major error and 1.45% (13/896) very major error. Thus, the dRAST system can be used to rapidly identify appropriate antimicrobial agents for the treatment of blood stream infection (BSI) and antibiotic-resistant strain infections.
62 schema:genre research_article
63 schema:inLanguage en
64 schema:isAccessibleForFree true
65 schema:isPartOf N5b8d087063714916b3da00bc2f00aacc
66 N9c7395cba3ce40469ecc2a965b839219
67 sg:journal.1045337
68 schema:name Direct, rapid antimicrobial susceptibility test from positive blood cultures based on microscopic imaging analysis
69 schema:pagination 1148
70 schema:productId N041c7405d24e48719718a166884c002b
71 N4c0db3522fd0451b8930f127ee3d977d
72 N57ea8d5869344de6865b9f7ba75e984d
73 Nbcfaa16433084d0c8295de9f2a8366e6
74 Nf8858d1ff1224edd8fd8f51743390ae2
75 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085055340
76 https://doi.org/10.1038/s41598-017-01278-2
77 schema:sdDatePublished 2019-04-10T21:40
78 schema:sdLicense https://scigraph.springernature.com/explorer/license/
79 schema:sdPublisher Nec5607f3c13443dc86ffcaea3feaac13
80 schema:url https://www.nature.com/articles/s41598-017-01278-2
81 sgo:license sg:explorer/license/
82 sgo:sdDataset articles
83 rdf:type schema:ScholarlyArticle
84 N01a2b2e6484a4a069d799af4fc07a7ed schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Microbial Sensitivity Tests
86 rdf:type schema:DefinedTerm
87 N02b6be091a294e6b8c979d44808457a3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Time Factors
89 rdf:type schema:DefinedTerm
90 N041c7405d24e48719718a166884c002b schema:name nlm_unique_id
91 schema:value 101563288
92 rdf:type schema:PropertyValue
93 N06cb0008c0e1460cb3f0627ddde485ca schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Meningitis, Bacterial
95 rdf:type schema:DefinedTerm
96 N082479cabcf948798c2d31bd9053bef8 rdf:first sg:person.0754535343.24
97 rdf:rest N5a75b8aa8f37476aaa2b83e4fb1113fb
98 N181274e8f9a54fe5b5ae9eda944a52f9 rdf:first sg:person.01326273120.12
99 rdf:rest Nb2eb4bf861e34b9c9e0a853429af10d8
100 N23d4bca6cf25445ba1fc70e3e915bb34 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Blood Culture
102 rdf:type schema:DefinedTerm
103 N272cac1752bd42fba7e367a565ea8e2f rdf:first sg:person.01346342474.77
104 rdf:rest Na27b9733de5e426e9c4056243e633bd0
105 N408183e4192b4973b29db50bacc6db27 rdf:first sg:person.01100214455.87
106 rdf:rest N272cac1752bd42fba7e367a565ea8e2f
107 N40ce54c6f1674a56a3207c0bdbe12f13 schema:affiliation https://www.grid.ac/institutes/grid.31501.36
108 schema:familyName Kim
109 schema:givenName Shin
110 rdf:type schema:Person
111 N4aa3c2a83d9e4a668ea6507824b39348 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Anti-Bacterial Agents
113 rdf:type schema:DefinedTerm
114 N4c0db3522fd0451b8930f127ee3d977d schema:name dimensions_id
115 schema:value pub.1085055340
116 rdf:type schema:PropertyValue
117 N57ea8d5869344de6865b9f7ba75e984d schema:name readcube_id
118 schema:value f4c880e881c30690f7b0f3b19b5da277fc6f8ec8ea3e123b03a31a78a7f0e8b0
119 rdf:type schema:PropertyValue
120 N5a75b8aa8f37476aaa2b83e4fb1113fb rdf:first sg:person.010646021163.16
121 rdf:rest rdf:nil
122 N5b8d087063714916b3da00bc2f00aacc schema:volumeNumber 7
123 rdf:type schema:PublicationVolume
124 N816280a96d0d4f928d72c187d84ac801 rdf:first sg:person.010155603320.46
125 rdf:rest Nbc09bdc4ce5148d0b8db5b1f77236ecb
126 N93150e8ef0074c63b04a0cc479624015 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Bacteremia
128 rdf:type schema:DefinedTerm
129 N9c7395cba3ce40469ecc2a965b839219 schema:issueNumber 1
130 rdf:type schema:PublicationIssue
131 Na27b9733de5e426e9c4056243e633bd0 rdf:first sg:person.01134047117.03
132 rdf:rest N082479cabcf948798c2d31bd9053bef8
133 Na442c166a331498d8aa3ea3a61be5723 rdf:first sg:person.011203640720.53
134 rdf:rest Ne2364042734c4c1e9bea297e52d20705
135 Na93be72479564f438fefac2cd2cab205 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Humans
137 rdf:type schema:DefinedTerm
138 Nb2eb4bf861e34b9c9e0a853429af10d8 rdf:first sg:person.013044456613.33
139 rdf:rest Nb48f49ee0a9c4e669209e2a3bcab1440
140 Nb48f49ee0a9c4e669209e2a3bcab1440 rdf:first sg:person.01054767010.31
141 rdf:rest Na442c166a331498d8aa3ea3a61be5723
142 Nb9158e63166b4db28fe38fcf97c6f428 rdf:first sg:person.01315544674.57
143 rdf:rest N408183e4192b4973b29db50bacc6db27
144 Nbc09bdc4ce5148d0b8db5b1f77236ecb rdf:first sg:person.011451515613.44
145 rdf:rest N181274e8f9a54fe5b5ae9eda944a52f9
146 Nbcfaa16433084d0c8295de9f2a8366e6 schema:name doi
147 schema:value 10.1038/s41598-017-01278-2
148 rdf:type schema:PropertyValue
149 Ne2364042734c4c1e9bea297e52d20705 rdf:first N40ce54c6f1674a56a3207c0bdbe12f13
150 rdf:rest Nb9158e63166b4db28fe38fcf97c6f428
151 Ne61c6b5969da4d6089131af11739e2d2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Microscopy
153 rdf:type schema:DefinedTerm
154 Ne8be9c192d0543428013321a35b2a7e2 rdf:first sg:person.01362730047.50
155 rdf:rest N816280a96d0d4f928d72c187d84ac801
156 Nec5607f3c13443dc86ffcaea3feaac13 schema:name Springer Nature - SN SciGraph project
157 rdf:type schema:Organization
158 Nf8858d1ff1224edd8fd8f51743390ae2 schema:name pubmed_id
159 schema:value 28442767
160 rdf:type schema:PropertyValue
161 Nfd11eede8e8b45ebb9e6118f0ae1c180 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Optical Imaging
163 rdf:type schema:DefinedTerm
164 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
165 schema:name Biological Sciences
166 rdf:type schema:DefinedTerm
167 anzsrc-for:0605 schema:inDefinedTermSet anzsrc-for:
168 schema:name Microbiology
169 rdf:type schema:DefinedTerm
170 sg:grant.7466677 http://pending.schema.org/fundedItem sg:pub.10.1038/s41598-017-01278-2
171 rdf:type schema:MonetaryGrant
172 sg:grant.7497494 http://pending.schema.org/fundedItem sg:pub.10.1038/s41598-017-01278-2
173 rdf:type schema:MonetaryGrant
174 sg:journal.1045337 schema:issn 2045-2322
175 schema:name Scientific Reports
176 rdf:type schema:Periodical
177 sg:person.010155603320.46 schema:affiliation https://www.grid.ac/institutes/grid.31501.36
178 schema:familyName Jeong
179 schema:givenName Hyun Yong
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010155603320.46
181 rdf:type schema:Person
182 sg:person.01054767010.31 schema:affiliation https://www.grid.ac/institutes/grid.412484.f
183 schema:familyName Jin
184 schema:givenName Bonghwan
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054767010.31
186 rdf:type schema:Person
187 sg:person.010646021163.16 schema:affiliation https://www.grid.ac/institutes/grid.412484.f
188 schema:familyName Kwon
189 schema:givenName Sunghoon
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010646021163.16
191 rdf:type schema:Person
192 sg:person.01100214455.87 schema:affiliation https://www.grid.ac/institutes/grid.412484.f
193 schema:familyName Kim
194 schema:givenName Hee Chan
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100214455.87
196 rdf:type schema:Person
197 sg:person.011203640720.53 schema:affiliation https://www.grid.ac/institutes/grid.31501.36
198 schema:familyName Lim
199 schema:givenName Taegeun
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011203640720.53
201 rdf:type schema:Person
202 sg:person.01134047117.03 schema:affiliation https://www.grid.ac/institutes/grid.412484.f
203 schema:familyName Song
204 schema:givenName Sang Hoon
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01134047117.03
206 rdf:type schema:Person
207 sg:person.011451515613.44 schema:affiliation https://www.grid.ac/institutes/grid.31501.36
208 schema:familyName Lee
209 schema:givenName Gi Yoon
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011451515613.44
211 rdf:type schema:Person
212 sg:person.013044456613.33 schema:affiliation https://www.grid.ac/institutes/grid.412484.f
213 schema:familyName Han
214 schema:givenName Shinhun
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013044456613.33
216 rdf:type schema:Person
217 sg:person.01315544674.57 schema:affiliation https://www.grid.ac/institutes/grid.412484.f
218 schema:familyName Kim
219 schema:givenName Dong Young
220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01315544674.57
221 rdf:type schema:Person
222 sg:person.01326273120.12 schema:affiliation https://www.grid.ac/institutes/grid.412484.f
223 schema:familyName Han
224 schema:givenName Sangkwon
225 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01326273120.12
226 rdf:type schema:Person
227 sg:person.01346342474.77 schema:affiliation https://www.grid.ac/institutes/grid.412484.f
228 schema:familyName Kim
229 schema:givenName Eui-Chong
230 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01346342474.77
231 rdf:type schema:Person
232 sg:person.01362730047.50 schema:affiliation https://www.grid.ac/institutes/grid.412484.f
233 schema:familyName Choi
234 schema:givenName Jungil
235 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362730047.50
236 rdf:type schema:Person
237 sg:person.0754535343.24 schema:affiliation https://www.grid.ac/institutes/grid.412484.f
238 schema:familyName Kim
239 schema:givenName Taek Soo
240 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0754535343.24
241 rdf:type schema:Person
242 sg:pub.10.1007/s10096-015-2492-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051465019
243 https://doi.org/10.1007/s10096-015-2492-9
244 rdf:type schema:CreativeWork
245 sg:pub.10.1038/ncomms6427 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026239375
246 https://doi.org/10.1038/ncomms6427
247 rdf:type schema:CreativeWork
248 sg:pub.10.1038/nm0712-997 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035696227
249 https://doi.org/10.1038/nm0712-997
250 rdf:type schema:CreativeWork
251 sg:pub.10.1038/nm1145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030272790
252 https://doi.org/10.1038/nm1145
253 rdf:type schema:CreativeWork
254 sg:pub.10.1186/cc4995 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002319592
255 https://doi.org/10.1186/cc4995
256 rdf:type schema:CreativeWork
257 https://app.dimensions.ai/details/publication/pub.1074358547 schema:CreativeWork
258 https://app.dimensions.ai/details/publication/pub.1074729513 schema:CreativeWork
259 https://app.dimensions.ai/details/publication/pub.1078897195 schema:CreativeWork
260 https://app.dimensions.ai/details/publication/pub.1080962191 schema:CreativeWork
261 https://app.dimensions.ai/details/publication/pub.1081775203 schema:CreativeWork
262 https://app.dimensions.ai/details/publication/pub.1082569890 schema:CreativeWork
263 https://doi.org/10.1016/j.diagmicrobio.2011.09.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016771179
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1016/j.jgar.2013.06.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023043977
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1016/j.juro.2010.09.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048607999
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1016/j.mimet.2013.12.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013325191
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1021/ac303282j schema:sameAs https://app.dimensions.ai/details/publication/pub.1055003778
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1021/ac4004248 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039318635
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1021/cb100336p schema:sameAs https://app.dimensions.ai/details/publication/pub.1047005096
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1039/c004691d schema:sameAs https://app.dimensions.ai/details/publication/pub.1029822787
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1039/c0lc00734j schema:sameAs https://app.dimensions.ai/details/publication/pub.1017062576
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1039/c2lc40531h schema:sameAs https://app.dimensions.ai/details/publication/pub.1000298710
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1039/c2lc41055a schema:sameAs https://app.dimensions.ai/details/publication/pub.1051964050
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1039/c5lc00375j schema:sameAs https://app.dimensions.ai/details/publication/pub.1039761973
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1086/647952 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020057169
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1093/bioinformatics/btu022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013849143
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1093/jac/dkn554 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008573006
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1097/00003246-200107000-00002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010433290
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1097/01.ccm.0000217961.75225.e9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015684145
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1111/j.1553-2712.2010.00871.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1031282129
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1126/scitranslmed.3009650 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062688471
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1128/aac.20.5.696 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027959065
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1128/aac.36.1.223 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033368093
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1128/aac.40.12.2686 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083079736
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1128/aac.45.12.3548-3554.2001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023644134
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1128/jcm.01171-14 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062711999
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1128/jcm.01831-09 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018357362
312 rdf:type schema:CreativeWork
313 https://doi.org/10.1128/jcm.05021-11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025102900
314 rdf:type schema:CreativeWork
315 https://doi.org/10.1128/jcm.41.10.4751-4754.2003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036499704
316 rdf:type schema:CreativeWork
317 https://doi.org/10.1128/jcm.42.1.7-11.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048249753
318 rdf:type schema:CreativeWork
319 https://doi.org/10.1128/jcm.42.4.1466-1470.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024030687
320 rdf:type schema:CreativeWork
321 https://doi.org/10.1128/jcm.42.8.3734-3738.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034549538
322 rdf:type schema:CreativeWork
323 https://doi.org/10.1146/annurev.cellbio.21.012704.131001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001236971
324 rdf:type schema:CreativeWork
325 https://doi.org/10.1146/annurev.micro.55.1.165 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001038130
326 rdf:type schema:CreativeWork
327 https://doi.org/10.1371/journal.pone.0087870 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029383617
328 rdf:type schema:CreativeWork
329 https://doi.org/10.3390/antibiotics4040455 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050103617
330 rdf:type schema:CreativeWork
331 https://doi.org/10.5858/arpa.2012-0651-oa schema:sameAs https://app.dimensions.ai/details/publication/pub.1018735150
332 rdf:type schema:CreativeWork
333 https://www.grid.ac/institutes/grid.31501.36 schema:alternateName Seoul National University
334 schema:name Department of Electrical and Computer Engineering, Institute of Engineering Research, Seoul National University, 08826, Seoul, Republic of Korea
335 Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University, 03080, Seoul, Republic of Korea
336 Institutes of Entrepreneurial BioConvergence, Seoul National University, 08826, Seoul, Republic of Korea
337 Program of Nano Science and Technology, Graduate School of Convergence Science and Technology, Seoul National University, 08826, Seoul, Republic of Korea
338 QuantaMatrix Inc., Medical Innovation Center, Seoul National University Hospital, 03080, Seoul, Republic of Korea
339 rdf:type schema:Organization
340 https://www.grid.ac/institutes/grid.412484.f schema:alternateName Seoul National University Hospital
341 schema:name Department of Biomedical Engineering, Seoul National University College of Medicine, 03080, Seoul, Republic of Korea
342 Department of Biomedical Engineering, Seoul National University Hospital, 03080, Seoul, Republic of Korea
343 Department of Electrical and Computer Engineering, Institute of Engineering Research, Seoul National University, 08826, Seoul, Republic of Korea
344 Department of Laboratory Medicine, Seoul National University Hospital, 03080, Seoul, Republic of Korea
345 Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University, 03080, Seoul, Republic of Korea
346 Institutes of Entrepreneurial BioConvergence, Seoul National University, 08826, Seoul, Republic of Korea
347 Program of Nano Science and Technology, Graduate School of Convergence Science and Technology, Seoul National University, 08826, Seoul, Republic of Korea
348 QuantaMatrix Inc., Medical Innovation Center, Seoul National University Hospital, 03080, Seoul, Republic of Korea
349 Seoul National University Hospital Biomedical Research Institute, Seoul National University Hospital, 03080, Seoul, Republic of Korea
350 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...