Understudied proteins: opportunities and challenges for functional proteomics View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2022-05-09

AUTHORS

Georg Kustatscher, Tom Collins, Anne-Claude Gingras, Tiannan Guo, Henning Hermjakob, Trey Ideker, Kathryn S. Lilley, Emma Lundberg, Edward M. Marcotte, Markus Ralser, Juri Rappsilber

ABSTRACT

Most research aiming at understanding the molecular foundations of life and disease has focused on a limited set of increasingly well-known proteins while the biological functions of many others remain poorly understood. We propose to form the Understudied Protein Initiative with the objective of reducing the annotation gap by systematically associating uncharacterized proteins with proteins of known function, thereby laying the groundwork for future detailed mechanistic studies. More... »

PAGES

774-779

References to SciGraph publications

  • 2014-12-15. Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes in NATURE GENETICS
  • 2012-12-13. A public-private partnership to unlock the untargeted kinome in NATURE CHEMICAL BIOLOGY
  • 2018-01-22. Gene annotation bias impedes biomedical research in SCIENTIFIC REPORTS
  • 2021-06-11. Reliable identification of protein-protein interactions by crosslinking mass spectrometry in NATURE COMMUNICATIONS
  • 2018-02-14. How many human proteoforms are there? in NATURE CHEMICAL BIOLOGY
  • 2007-09-27. Analysis and validation of proteomic data generated by tandem mass spectrometry in NATURE METHODS
  • 2013-01-27. A large-scale evaluation of computational protein function prediction in NATURE METHODS
  • 2017-11-01. The most popular genes in the human genome in NATURE
  • 2000-11. Creating a structural genomics consortium in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2019-01-18. Spatial proteomics: a powerful discovery tool for cell biology in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2013-05-15. Variation and genetic control of protein abundance in humans in NATURE
  • 2018-10-29. Cross-linking mass spectrometry: methods and applications in structural, molecular and systems biology in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2022-05-09. An open invitation to the Understudied Proteins Initiative in NATURE BIOTECHNOLOGY
  • 2011-02-09. Too many roads not taken in NATURE
  • 2020-06-17. The proteome landscape of the kingdoms of life in NATURE
  • 2019-09-16. Estimating cumulative point prevalence of rare diseases: analysis of the Orphanet database in EUROPEAN JOURNAL OF HUMAN GENETICS
  • 2020-09-03. A hypothesis is a liability in GENOME BIOLOGY
  • 1999-11. A combined algorithm for genome-wide prediction of protein function in NATURE
  • 2021-07-15. Highly accurate protein structure prediction with AlphaFold in NATURE
  • 2010-03. The (un)targeted cancer kinome in NATURE CHEMICAL BIOLOGY
  • 2003-05-12. High-throughput classification of yeast mutants for functional genomics using metabolic footprinting in NATURE BIOTECHNOLOGY
  • 2003-05-12. Global protein function prediction from protein-protein interaction networks in NATURE BIOTECHNOLOGY
  • 2007-04-30. Power-law-like distributions in biomedical publications and research funding in GENOME BIOLOGY
  • 2020-02-17. Single-cell analysis targeting the proteome in NATURE REVIEWS CHEMISTRY
  • 2018-03-23. Unexplored therapeutic opportunities in the human genome in NATURE REVIEWS DRUG DISCOVERY
  • 2021-11-24. A multi-scale map of cell structure fusing protein images and interactions in NATURE
  • 2020-10-16. A high-stringency blueprint of the human proteome in NATURE COMMUNICATIONS
  • 2011-05-29. An integrated approach to characterize genetic interaction networks in yeast metabolism in NATURE GENETICS
  • 2020-04-08. A reference map of the human binary protein interactome in NATURE
  • 2019-12-24. PROTACs: great opportunities for academia and industry in SIGNAL TRANSDUCTION AND TARGETED THERAPY
  • 2019-11-04. Co-regulation map of the human proteome enables identification of protein functions in NATURE BIOTECHNOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/s41592-022-01454-x

    DOI

    http://dx.doi.org/10.1038/s41592-022-01454-x

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1147727453

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/35534633


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biochemistry and Cell Biology", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mass Spectrometry", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Proteins", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Proteomics", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Institute of Quantitative Biology, Biochemistry and Biotechnology, University of Edinburgh, Edinburgh, UK", 
              "id": "http://www.grid.ac/institutes/grid.4305.2", 
              "name": [
                "Institute of Quantitative Biology, Biochemistry and Biotechnology, University of Edinburgh, Edinburgh, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kustatscher", 
            "givenName": "Georg", 
            "id": "sg:person.01253202704.19", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01253202704.19"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Wellcome Trust, London, UK", 
              "id": "http://www.grid.ac/institutes/grid.52788.30", 
              "name": [
                "Wellcome Trust, London, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Collins", 
            "givenName": "Tom", 
            "id": "sg:person.015653420774.42", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015653420774.42"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada", 
              "id": "http://www.grid.ac/institutes/grid.17063.33", 
              "name": [
                "Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario, Canada", 
                "Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Gingras", 
            "givenName": "Anne-Claude", 
            "id": "sg:person.01360221101.11", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01360221101.11"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Institute of Basic Medical Sciences, Westlake Institute for Advanced Study, Hangzhou, China", 
              "id": "http://www.grid.ac/institutes/grid.494629.4", 
              "name": [
                "Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China", 
                "Institute of Basic Medical Sciences, Westlake Institute for Advanced Study, Hangzhou, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Guo", 
            "givenName": "Tiannan", 
            "id": "sg:person.01012430176.23", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012430176.23"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK", 
              "id": "http://www.grid.ac/institutes/grid.225360.0", 
              "name": [
                "European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hermjakob", 
            "givenName": "Henning", 
            "id": "sg:person.01070655672.90", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070655672.90"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Division of Genetics, Department of Medicine, University of California San Diego, La Jolla, CA, USA", 
              "id": "http://www.grid.ac/institutes/grid.266100.3", 
              "name": [
                "Division of Genetics, Department of Medicine, University of California San Diego, La Jolla, CA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ideker", 
            "givenName": "Trey", 
            "id": "sg:person.01302562670.97", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302562670.97"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cambridge Centre for Proteomics, Department of Biochemistry, University of Cambridge, Cambridge, UK", 
              "id": "http://www.grid.ac/institutes/grid.5335.0", 
              "name": [
                "Cambridge Centre for Proteomics, Department of Biochemistry, University of Cambridge, Cambridge, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lilley", 
            "givenName": "Kathryn S.", 
            "id": "sg:person.0673527050.80", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673527050.80"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Chan Zuckerberg Biohub, San Francisco, CA, USA", 
              "id": "http://www.grid.ac/institutes/grid.499295.a", 
              "name": [
                "Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH-Royal Institute of Technology, Stockholm, Sweden", 
                "Department of Bioengineering, Stanford University, Stanford, CA, USA", 
                "Department of Pathology, Stanford University, Stanford, CA, USA", 
                "Chan Zuckerberg Biohub, San Francisco, CA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lundberg", 
            "givenName": "Emma", 
            "id": "sg:person.01056523743.14", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056523743.14"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Molecular Biosciences, Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, TX, USA", 
              "id": "http://www.grid.ac/institutes/grid.89336.37", 
              "name": [
                "Department of Molecular Biosciences, Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, TX, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Marcotte", 
            "givenName": "Edward M.", 
            "id": "sg:person.01246405713.35", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246405713.35"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "The Molecular Biology of Metabolism Laboratory, the Francis Crick Institute, London, UK", 
              "id": "http://www.grid.ac/institutes/grid.451388.3", 
              "name": [
                "Department of Biochemistry, Charit\u00e9 University Medicine, Berlin, Germany", 
                "The Molecular Biology of Metabolism Laboratory, the Francis Crick Institute, London, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ralser", 
            "givenName": "Markus", 
            "id": "sg:person.01070543134.75", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070543134.75"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK", 
              "id": "http://www.grid.ac/institutes/grid.449997.e", 
              "name": [
                "Bioanalytics, Technische Universit\u00e4t Berlin, Berlin, Germany", 
                "Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rappsilber", 
            "givenName": "Juri", 
            "id": "sg:person.0747617371.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0747617371.25"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1186/gb-2007-8-4-404", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039176765", 
              "https://doi.org/10.1186/gb-2007-8-4-404"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41586-021-03819-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1139691916", 
              "https://doi.org/10.1038/s41586-021-03819-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41431-019-0508-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1121006597", 
              "https://doi.org/10.1038/s41431-019-0508-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41587-019-0298-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1122311290", 
              "https://doi.org/10.1038/s41587-019-0298-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41467-021-23666-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1138782233", 
              "https://doi.org/10.1038/s41467-021-23666-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13059-020-02133-w", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1130565898", 
              "https://doi.org/10.1186/s13059-020-02133-w"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41467-020-19045-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1131767503", 
              "https://doi.org/10.1038/s41467-020-19045-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/d41586-017-07291-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092912803", 
              "https://doi.org/10.1038/d41586-017-07291-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41580-018-0094-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1111501782", 
              "https://doi.org/10.1038/s41580-018-0094-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41598-018-19333-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1100427010", 
              "https://doi.org/10.1038/s41598-018-19333-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41586-020-2402-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1128525826", 
              "https://doi.org/10.1038/s41586-020-2402-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth1088", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051930348", 
              "https://doi.org/10.1038/nmeth1088"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41392-019-0101-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1123606099", 
              "https://doi.org/10.1038/s41392-019-0101-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/80726", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039793336", 
              "https://doi.org/10.1038/80726"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41587-022-01316-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1147727277", 
              "https://doi.org/10.1038/s41587-022-01316-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/47048", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029164285", 
              "https://doi.org/10.1038/47048"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nchembio.1113", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051938988", 
              "https://doi.org/10.1038/nchembio.1113"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41586-021-04115-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1142907100", 
              "https://doi.org/10.1038/s41586-021-04115-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt823", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051888256", 
              "https://doi.org/10.1038/nbt823"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature12223", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021573692", 
              "https://doi.org/10.1038/nature12223"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41586-020-2188-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1126270227", 
              "https://doi.org/10.1038/s41586-020-2188-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.3168", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052675624", 
              "https://doi.org/10.1038/ng.3168"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41570-020-0162-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1124911111", 
              "https://doi.org/10.1038/s41570-020-0162-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41594-018-0147-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1107804228", 
              "https://doi.org/10.1038/s41594-018-0147-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nchembio.297", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053614031", 
              "https://doi.org/10.1038/nchembio.297"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrd.2018.14", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1101184086", 
              "https://doi.org/10.1038/nrd.2018.14"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt825", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019729549", 
              "https://doi.org/10.1038/nbt825"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nchembio.2576", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1101033134", 
              "https://doi.org/10.1038/nchembio.2576"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.2340", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046100259", 
              "https://doi.org/10.1038/nmeth.2340"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.846", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031314097", 
              "https://doi.org/10.1038/ng.846"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/470163a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045497536", 
              "https://doi.org/10.1038/470163a"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2022-05-09", 
        "datePublishedReg": "2022-05-09", 
        "description": "Most research aiming at understanding the molecular foundations of life and disease has focused on a limited set of increasingly well-known proteins while the biological functions of many others remain poorly understood. We propose to form the Understudied Protein Initiative with the objective of reducing the annotation gap by systematically associating uncharacterized proteins with proteins of known function, thereby laying the groundwork for future detailed mechanistic studies.", 
        "genre": "article", 
        "id": "sg:pub.10.1038/s41592-022-01454-x", 
        "isAccessibleForFree": true, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.8454815", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.10028979", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1033763", 
            "issn": [
              "1548-7091", 
              "1548-7105"
            ], 
            "name": "Nature Methods", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "7", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "19"
          }
        ], 
        "keywords": [
          "uncharacterized proteins", 
          "functional proteomics", 
          "annotation gap", 
          "molecular foundation", 
          "biological functions", 
          "protein", 
          "detailed mechanistic studies", 
          "mechanistic studies", 
          "proteomics", 
          "limited set", 
          "function", 
          "most research", 
          "groundwork", 
          "disease", 
          "study", 
          "set", 
          "opportunities", 
          "foundation", 
          "challenges", 
          "research", 
          "gap", 
          "life", 
          "objective", 
          "initiatives"
        ], 
        "name": "Understudied proteins: opportunities and challenges for functional proteomics", 
        "pagination": "774-779", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1147727453"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/s41592-022-01454-x"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "35534633"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/s41592-022-01454-x", 
          "https://app.dimensions.ai/details/publication/pub.1147727453"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-09-02T16:08", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_944.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1038/s41592-022-01454-x"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41592-022-01454-x'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41592-022-01454-x'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41592-022-01454-x'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41592-022-01454-x'


     

    This table displays all metadata directly associated to this object as RDF triples.

    332 TRIPLES      21 PREDICATES      83 URIs      44 LITERALS      10 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/s41592-022-01454-x schema:about N55ff3e2362a94278a3a95c51ba635641
    2 Nca6c015247834a278f6fd0c4f48b0e63
    3 Nef1c920352714224b8a1ad95125c8d2c
    4 anzsrc-for:06
    5 anzsrc-for:0601
    6 schema:author N82bc7a9157a94a5dba3f4ee11d582a7c
    7 schema:citation sg:pub.10.1038/470163a
    8 sg:pub.10.1038/47048
    9 sg:pub.10.1038/80726
    10 sg:pub.10.1038/d41586-017-07291-9
    11 sg:pub.10.1038/nature12223
    12 sg:pub.10.1038/nbt823
    13 sg:pub.10.1038/nbt825
    14 sg:pub.10.1038/nchembio.1113
    15 sg:pub.10.1038/nchembio.2576
    16 sg:pub.10.1038/nchembio.297
    17 sg:pub.10.1038/ng.3168
    18 sg:pub.10.1038/ng.846
    19 sg:pub.10.1038/nmeth.2340
    20 sg:pub.10.1038/nmeth1088
    21 sg:pub.10.1038/nrd.2018.14
    22 sg:pub.10.1038/s41392-019-0101-6
    23 sg:pub.10.1038/s41431-019-0508-0
    24 sg:pub.10.1038/s41467-020-19045-9
    25 sg:pub.10.1038/s41467-021-23666-z
    26 sg:pub.10.1038/s41570-020-0162-7
    27 sg:pub.10.1038/s41580-018-0094-y
    28 sg:pub.10.1038/s41586-020-2188-x
    29 sg:pub.10.1038/s41586-020-2402-x
    30 sg:pub.10.1038/s41586-021-03819-2
    31 sg:pub.10.1038/s41586-021-04115-9
    32 sg:pub.10.1038/s41587-019-0298-5
    33 sg:pub.10.1038/s41587-022-01316-z
    34 sg:pub.10.1038/s41594-018-0147-0
    35 sg:pub.10.1038/s41598-018-19333-x
    36 sg:pub.10.1186/gb-2007-8-4-404
    37 sg:pub.10.1186/s13059-020-02133-w
    38 schema:datePublished 2022-05-09
    39 schema:datePublishedReg 2022-05-09
    40 schema:description Most research aiming at understanding the molecular foundations of life and disease has focused on a limited set of increasingly well-known proteins while the biological functions of many others remain poorly understood. We propose to form the Understudied Protein Initiative with the objective of reducing the annotation gap by systematically associating uncharacterized proteins with proteins of known function, thereby laying the groundwork for future detailed mechanistic studies.
    41 schema:genre article
    42 schema:isAccessibleForFree true
    43 schema:isPartOf N1b986ae9928045968ab37efd0bdf1f55
    44 N5d46b19f19f448fe8d559f061da8fb2d
    45 sg:journal.1033763
    46 schema:keywords annotation gap
    47 biological functions
    48 challenges
    49 detailed mechanistic studies
    50 disease
    51 foundation
    52 function
    53 functional proteomics
    54 gap
    55 groundwork
    56 initiatives
    57 life
    58 limited set
    59 mechanistic studies
    60 molecular foundation
    61 most research
    62 objective
    63 opportunities
    64 protein
    65 proteomics
    66 research
    67 set
    68 study
    69 uncharacterized proteins
    70 schema:name Understudied proteins: opportunities and challenges for functional proteomics
    71 schema:pagination 774-779
    72 schema:productId N7e027d8d6126430cb5b326512c6ee126
    73 N897c8cfb52b2485ebdf90c2a69c6248c
    74 Nf20fe3193d714b2bb7bb8a85a4b7c2d0
    75 schema:sameAs https://app.dimensions.ai/details/publication/pub.1147727453
    76 https://doi.org/10.1038/s41592-022-01454-x
    77 schema:sdDatePublished 2022-09-02T16:08
    78 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    79 schema:sdPublisher N06dcb260169947f6a4e3b79759ac3118
    80 schema:url https://doi.org/10.1038/s41592-022-01454-x
    81 sgo:license sg:explorer/license/
    82 sgo:sdDataset articles
    83 rdf:type schema:ScholarlyArticle
    84 N062a8510f4194ef9be616b16741b349a rdf:first sg:person.01012430176.23
    85 rdf:rest N1f19bcfd3d5b41f59468ced58e33ed2e
    86 N06dcb260169947f6a4e3b79759ac3118 schema:name Springer Nature - SN SciGraph project
    87 rdf:type schema:Organization
    88 N0e97e815b44e43ee99861a6fd8ac1168 rdf:first sg:person.01246405713.35
    89 rdf:rest Nd1ddfafd58304d56842a1e11e00421b0
    90 N1b986ae9928045968ab37efd0bdf1f55 schema:volumeNumber 19
    91 rdf:type schema:PublicationVolume
    92 N1f19bcfd3d5b41f59468ced58e33ed2e rdf:first sg:person.01070655672.90
    93 rdf:rest Nb6f7c70c7d014ca38480e505472c143c
    94 N4d9473f09ed74b4db681913c1ff089d5 rdf:first sg:person.0673527050.80
    95 rdf:rest N76d69cf778974b4aa284ce890db78dda
    96 N55ff3e2362a94278a3a95c51ba635641 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    97 schema:name Proteomics
    98 rdf:type schema:DefinedTerm
    99 N5d46b19f19f448fe8d559f061da8fb2d schema:issueNumber 7
    100 rdf:type schema:PublicationIssue
    101 N76d69cf778974b4aa284ce890db78dda rdf:first sg:person.01056523743.14
    102 rdf:rest N0e97e815b44e43ee99861a6fd8ac1168
    103 N7de9c87c1afb41fb8153e55eeae020f9 rdf:first sg:person.01360221101.11
    104 rdf:rest N062a8510f4194ef9be616b16741b349a
    105 N7e027d8d6126430cb5b326512c6ee126 schema:name pubmed_id
    106 schema:value 35534633
    107 rdf:type schema:PropertyValue
    108 N82bc7a9157a94a5dba3f4ee11d582a7c rdf:first sg:person.01253202704.19
    109 rdf:rest Nc812d3b85d0c44bdbfbfd05d779c1f35
    110 N897c8cfb52b2485ebdf90c2a69c6248c schema:name dimensions_id
    111 schema:value pub.1147727453
    112 rdf:type schema:PropertyValue
    113 Na18742e152fd4739b7cb7f54b09e0a2c rdf:first sg:person.0747617371.25
    114 rdf:rest rdf:nil
    115 Nb6f7c70c7d014ca38480e505472c143c rdf:first sg:person.01302562670.97
    116 rdf:rest N4d9473f09ed74b4db681913c1ff089d5
    117 Nc812d3b85d0c44bdbfbfd05d779c1f35 rdf:first sg:person.015653420774.42
    118 rdf:rest N7de9c87c1afb41fb8153e55eeae020f9
    119 Nca6c015247834a278f6fd0c4f48b0e63 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    120 schema:name Mass Spectrometry
    121 rdf:type schema:DefinedTerm
    122 Nd1ddfafd58304d56842a1e11e00421b0 rdf:first sg:person.01070543134.75
    123 rdf:rest Na18742e152fd4739b7cb7f54b09e0a2c
    124 Nef1c920352714224b8a1ad95125c8d2c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    125 schema:name Proteins
    126 rdf:type schema:DefinedTerm
    127 Nf20fe3193d714b2bb7bb8a85a4b7c2d0 schema:name doi
    128 schema:value 10.1038/s41592-022-01454-x
    129 rdf:type schema:PropertyValue
    130 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    131 schema:name Biological Sciences
    132 rdf:type schema:DefinedTerm
    133 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
    134 schema:name Biochemistry and Cell Biology
    135 rdf:type schema:DefinedTerm
    136 sg:grant.10028979 http://pending.schema.org/fundedItem sg:pub.10.1038/s41592-022-01454-x
    137 rdf:type schema:MonetaryGrant
    138 sg:grant.8454815 http://pending.schema.org/fundedItem sg:pub.10.1038/s41592-022-01454-x
    139 rdf:type schema:MonetaryGrant
    140 sg:journal.1033763 schema:issn 1548-7091
    141 1548-7105
    142 schema:name Nature Methods
    143 schema:publisher Springer Nature
    144 rdf:type schema:Periodical
    145 sg:person.01012430176.23 schema:affiliation grid-institutes:grid.494629.4
    146 schema:familyName Guo
    147 schema:givenName Tiannan
    148 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012430176.23
    149 rdf:type schema:Person
    150 sg:person.01056523743.14 schema:affiliation grid-institutes:grid.499295.a
    151 schema:familyName Lundberg
    152 schema:givenName Emma
    153 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056523743.14
    154 rdf:type schema:Person
    155 sg:person.01070543134.75 schema:affiliation grid-institutes:grid.451388.3
    156 schema:familyName Ralser
    157 schema:givenName Markus
    158 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070543134.75
    159 rdf:type schema:Person
    160 sg:person.01070655672.90 schema:affiliation grid-institutes:grid.225360.0
    161 schema:familyName Hermjakob
    162 schema:givenName Henning
    163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070655672.90
    164 rdf:type schema:Person
    165 sg:person.01246405713.35 schema:affiliation grid-institutes:grid.89336.37
    166 schema:familyName Marcotte
    167 schema:givenName Edward M.
    168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246405713.35
    169 rdf:type schema:Person
    170 sg:person.01253202704.19 schema:affiliation grid-institutes:grid.4305.2
    171 schema:familyName Kustatscher
    172 schema:givenName Georg
    173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01253202704.19
    174 rdf:type schema:Person
    175 sg:person.01302562670.97 schema:affiliation grid-institutes:grid.266100.3
    176 schema:familyName Ideker
    177 schema:givenName Trey
    178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302562670.97
    179 rdf:type schema:Person
    180 sg:person.01360221101.11 schema:affiliation grid-institutes:grid.17063.33
    181 schema:familyName Gingras
    182 schema:givenName Anne-Claude
    183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01360221101.11
    184 rdf:type schema:Person
    185 sg:person.015653420774.42 schema:affiliation grid-institutes:grid.52788.30
    186 schema:familyName Collins
    187 schema:givenName Tom
    188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015653420774.42
    189 rdf:type schema:Person
    190 sg:person.0673527050.80 schema:affiliation grid-institutes:grid.5335.0
    191 schema:familyName Lilley
    192 schema:givenName Kathryn S.
    193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673527050.80
    194 rdf:type schema:Person
    195 sg:person.0747617371.25 schema:affiliation grid-institutes:grid.449997.e
    196 schema:familyName Rappsilber
    197 schema:givenName Juri
    198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0747617371.25
    199 rdf:type schema:Person
    200 sg:pub.10.1038/470163a schema:sameAs https://app.dimensions.ai/details/publication/pub.1045497536
    201 https://doi.org/10.1038/470163a
    202 rdf:type schema:CreativeWork
    203 sg:pub.10.1038/47048 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029164285
    204 https://doi.org/10.1038/47048
    205 rdf:type schema:CreativeWork
    206 sg:pub.10.1038/80726 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039793336
    207 https://doi.org/10.1038/80726
    208 rdf:type schema:CreativeWork
    209 sg:pub.10.1038/d41586-017-07291-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092912803
    210 https://doi.org/10.1038/d41586-017-07291-9
    211 rdf:type schema:CreativeWork
    212 sg:pub.10.1038/nature12223 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021573692
    213 https://doi.org/10.1038/nature12223
    214 rdf:type schema:CreativeWork
    215 sg:pub.10.1038/nbt823 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051888256
    216 https://doi.org/10.1038/nbt823
    217 rdf:type schema:CreativeWork
    218 sg:pub.10.1038/nbt825 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019729549
    219 https://doi.org/10.1038/nbt825
    220 rdf:type schema:CreativeWork
    221 sg:pub.10.1038/nchembio.1113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051938988
    222 https://doi.org/10.1038/nchembio.1113
    223 rdf:type schema:CreativeWork
    224 sg:pub.10.1038/nchembio.2576 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101033134
    225 https://doi.org/10.1038/nchembio.2576
    226 rdf:type schema:CreativeWork
    227 sg:pub.10.1038/nchembio.297 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053614031
    228 https://doi.org/10.1038/nchembio.297
    229 rdf:type schema:CreativeWork
    230 sg:pub.10.1038/ng.3168 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052675624
    231 https://doi.org/10.1038/ng.3168
    232 rdf:type schema:CreativeWork
    233 sg:pub.10.1038/ng.846 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031314097
    234 https://doi.org/10.1038/ng.846
    235 rdf:type schema:CreativeWork
    236 sg:pub.10.1038/nmeth.2340 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046100259
    237 https://doi.org/10.1038/nmeth.2340
    238 rdf:type schema:CreativeWork
    239 sg:pub.10.1038/nmeth1088 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051930348
    240 https://doi.org/10.1038/nmeth1088
    241 rdf:type schema:CreativeWork
    242 sg:pub.10.1038/nrd.2018.14 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101184086
    243 https://doi.org/10.1038/nrd.2018.14
    244 rdf:type schema:CreativeWork
    245 sg:pub.10.1038/s41392-019-0101-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1123606099
    246 https://doi.org/10.1038/s41392-019-0101-6
    247 rdf:type schema:CreativeWork
    248 sg:pub.10.1038/s41431-019-0508-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1121006597
    249 https://doi.org/10.1038/s41431-019-0508-0
    250 rdf:type schema:CreativeWork
    251 sg:pub.10.1038/s41467-020-19045-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1131767503
    252 https://doi.org/10.1038/s41467-020-19045-9
    253 rdf:type schema:CreativeWork
    254 sg:pub.10.1038/s41467-021-23666-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1138782233
    255 https://doi.org/10.1038/s41467-021-23666-z
    256 rdf:type schema:CreativeWork
    257 sg:pub.10.1038/s41570-020-0162-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1124911111
    258 https://doi.org/10.1038/s41570-020-0162-7
    259 rdf:type schema:CreativeWork
    260 sg:pub.10.1038/s41580-018-0094-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1111501782
    261 https://doi.org/10.1038/s41580-018-0094-y
    262 rdf:type schema:CreativeWork
    263 sg:pub.10.1038/s41586-020-2188-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1126270227
    264 https://doi.org/10.1038/s41586-020-2188-x
    265 rdf:type schema:CreativeWork
    266 sg:pub.10.1038/s41586-020-2402-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1128525826
    267 https://doi.org/10.1038/s41586-020-2402-x
    268 rdf:type schema:CreativeWork
    269 sg:pub.10.1038/s41586-021-03819-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1139691916
    270 https://doi.org/10.1038/s41586-021-03819-2
    271 rdf:type schema:CreativeWork
    272 sg:pub.10.1038/s41586-021-04115-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1142907100
    273 https://doi.org/10.1038/s41586-021-04115-9
    274 rdf:type schema:CreativeWork
    275 sg:pub.10.1038/s41587-019-0298-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1122311290
    276 https://doi.org/10.1038/s41587-019-0298-5
    277 rdf:type schema:CreativeWork
    278 sg:pub.10.1038/s41587-022-01316-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1147727277
    279 https://doi.org/10.1038/s41587-022-01316-z
    280 rdf:type schema:CreativeWork
    281 sg:pub.10.1038/s41594-018-0147-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1107804228
    282 https://doi.org/10.1038/s41594-018-0147-0
    283 rdf:type schema:CreativeWork
    284 sg:pub.10.1038/s41598-018-19333-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1100427010
    285 https://doi.org/10.1038/s41598-018-19333-x
    286 rdf:type schema:CreativeWork
    287 sg:pub.10.1186/gb-2007-8-4-404 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039176765
    288 https://doi.org/10.1186/gb-2007-8-4-404
    289 rdf:type schema:CreativeWork
    290 sg:pub.10.1186/s13059-020-02133-w schema:sameAs https://app.dimensions.ai/details/publication/pub.1130565898
    291 https://doi.org/10.1186/s13059-020-02133-w
    292 rdf:type schema:CreativeWork
    293 grid-institutes:grid.17063.33 schema:alternateName Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada
    294 schema:name Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada
    295 Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario, Canada
    296 rdf:type schema:Organization
    297 grid-institutes:grid.225360.0 schema:alternateName European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK
    298 schema:name European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK
    299 rdf:type schema:Organization
    300 grid-institutes:grid.266100.3 schema:alternateName Division of Genetics, Department of Medicine, University of California San Diego, La Jolla, CA, USA
    301 schema:name Division of Genetics, Department of Medicine, University of California San Diego, La Jolla, CA, USA
    302 rdf:type schema:Organization
    303 grid-institutes:grid.4305.2 schema:alternateName Institute of Quantitative Biology, Biochemistry and Biotechnology, University of Edinburgh, Edinburgh, UK
    304 schema:name Institute of Quantitative Biology, Biochemistry and Biotechnology, University of Edinburgh, Edinburgh, UK
    305 rdf:type schema:Organization
    306 grid-institutes:grid.449997.e schema:alternateName Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK
    307 schema:name Bioanalytics, Technische Universität Berlin, Berlin, Germany
    308 Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, UK
    309 rdf:type schema:Organization
    310 grid-institutes:grid.451388.3 schema:alternateName The Molecular Biology of Metabolism Laboratory, the Francis Crick Institute, London, UK
    311 schema:name Department of Biochemistry, Charité University Medicine, Berlin, Germany
    312 The Molecular Biology of Metabolism Laboratory, the Francis Crick Institute, London, UK
    313 rdf:type schema:Organization
    314 grid-institutes:grid.494629.4 schema:alternateName Institute of Basic Medical Sciences, Westlake Institute for Advanced Study, Hangzhou, China
    315 schema:name Institute of Basic Medical Sciences, Westlake Institute for Advanced Study, Hangzhou, China
    316 Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China
    317 rdf:type schema:Organization
    318 grid-institutes:grid.499295.a schema:alternateName Chan Zuckerberg Biohub, San Francisco, CA, USA
    319 schema:name Chan Zuckerberg Biohub, San Francisco, CA, USA
    320 Department of Bioengineering, Stanford University, Stanford, CA, USA
    321 Department of Pathology, Stanford University, Stanford, CA, USA
    322 Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH-Royal Institute of Technology, Stockholm, Sweden
    323 rdf:type schema:Organization
    324 grid-institutes:grid.52788.30 schema:alternateName Wellcome Trust, London, UK
    325 schema:name Wellcome Trust, London, UK
    326 rdf:type schema:Organization
    327 grid-institutes:grid.5335.0 schema:alternateName Cambridge Centre for Proteomics, Department of Biochemistry, University of Cambridge, Cambridge, UK
    328 schema:name Cambridge Centre for Proteomics, Department of Biochemistry, University of Cambridge, Cambridge, UK
    329 rdf:type schema:Organization
    330 grid-institutes:grid.89336.37 schema:alternateName Department of Molecular Biosciences, Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, TX, USA
    331 schema:name Department of Molecular Biosciences, Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, TX, USA
    332 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...