The evolutionary history of vertebrate RNA viruses View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-04-04

AUTHORS

Mang Shi, Xian-Dan Lin, Xiao Chen, Jun-Hua Tian, Liang-Jun Chen, Kun Li, Wen Wang, John-Sebastian Eden, Jin-Jin Shen, Li Liu, Edward C. Holmes, Yong-Zhen Zhang

ABSTRACT

Our understanding of the diversity and evolution of vertebrate RNA viruses is largely limited to those found in mammalian and avian hosts and associated with overt disease. Here, using a large-scale meta-transcriptomic approach, we discover 214 vertebrate-associated viruses in reptiles, amphibians, lungfish, ray-finned fish, cartilaginous fish and jawless fish. The newly discovered viruses appear in every family or genus of RNA virus associated with vertebrate infection, including those containing human pathogens such as influenza virus, the Arenaviridae and Filoviridae families, and have branching orders that broadly reflected the phylogenetic history of their hosts. We establish a long evolutionary history for most groups of vertebrate RNA virus, and support this by evaluating evolutionary timescales using dated orthologous endogenous virus elements. We also identify new vertebrate-specific RNA viruses and genome architectures, and re-evaluate the evolution of vector-borne RNA viruses. In summary, this study reveals diverse virus–host associations across the entire evolutionary history of the vertebrates. More... »

PAGES

197-202

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41586-018-0012-7

DOI

http://dx.doi.org/10.1038/s41586-018-0012-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1101862110

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29618816


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61 influenza virus
62 jawless fish
63 long evolutionary history
64 lungfish
65 meta-transcriptomic approach
66 most groups
67 order
68 overt disease
69 pathogens
70 phylogenetic history
71 ray-finned fishes
72 reptiles
73 study
74 summary
75 timescales
76 understanding
77 vector-borne RNA viruses
78 vertebrate RNA viruses
79 vertebrate infection
80 vertebrate-associated viruses
81 vertebrates
82 virus
83 virus-host associations
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