Ontology type: schema:ScholarlyArticle Open Access: True
2020-09-04
AUTHORS ABSTRACTObservational findings achieved during the past two decades suggest that the intestinal microbiota may contribute to the metabolic health of the human host and, when aberrant, to the pathogenesis of various common metabolic disorders including obesity, type 2 diabetes, non-alcoholic liver disease, cardio-metabolic diseases and malnutrition. However, to gain a mechanistic understanding of how the gut microbiota affects host metabolism, research is moving from descriptive microbiota census analyses to cause-and-effect studies. Joint analyses of high-throughput human multi-omics data, including metagenomics and metabolomics data, together with measures of host physiology and mechanistic experiments in humans, animals and cells hold potential as initial steps in the identification of potential molecular mechanisms behind reported associations. In this Review, we discuss the current knowledge on how gut microbiota and derived microbial compounds may link to metabolism of the healthy host or to the pathogenesis of common metabolic diseases. We highlight examples of microbiota-targeted interventions aiming to optimize metabolic health, and we provide perspectives for future basic and translational investigations within the nascent and promising research field. More... »
PAGES55-71
http://scigraph.springernature.com/pub.10.1038/s41579-020-0433-9
DOIhttp://dx.doi.org/10.1038/s41579-020-0433-9
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1130573371
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/32887946
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biological Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biochemistry and Cell Biology",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Animals",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Biodiversity",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Disease Susceptibility",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Energy Metabolism",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Gastrointestinal Microbiome",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Health",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Metabolic Diseases",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark",
"id": "http://www.grid.ac/institutes/grid.5254.6",
"name": [
"Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark"
],
"type": "Organization"
},
"familyName": "Fan",
"givenName": "Yong",
"id": "sg:person.0653147314.27",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0653147314.27"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark",
"id": "http://www.grid.ac/institutes/grid.5254.6",
"name": [
"Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark"
],
"type": "Organization"
},
"familyName": "Pedersen",
"givenName": "Oluf",
"id": "sg:person.0765447455.52",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0765447455.52"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1186/1471-2105-9-559",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020312314",
"https://doi.org/10.1186/1471-2105-9-559"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrendo.2014.210",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052714142",
"https://doi.org/10.1038/nrendo.2014.210"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature08821",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050498034",
"https://doi.org/10.1038/nature08821"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ncomms11960",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042964383",
"https://doi.org/10.1038/ncomms11960"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature00887",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045194098",
"https://doi.org/10.1038/nature00887"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41596-018-0064-z",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1107943224",
"https://doi.org/10.1038/s41596-018-0064-z"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature25973",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1101264718",
"https://doi.org/10.1038/nature25973"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00464-017-5747-y",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1091053459",
"https://doi.org/10.1007/s00464-017-5747-y"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41424-018-0025-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1104159918",
"https://doi.org/10.1038/s41424-018-0025-4"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/srep46337",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1084757425",
"https://doi.org/10.1038/srep46337"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00425340",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031193922",
"https://doi.org/10.1007/bf00425340"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41564-018-0257-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1107689529",
"https://doi.org/10.1038/s41564-018-0257-9"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrendo.2014.29",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050836485",
"https://doi.org/10.1038/nrendo.2014.29"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature18309",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044560114",
"https://doi.org/10.1038/nature18309"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00125-014-3270-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013134889",
"https://doi.org/10.1007/s00125-014-3270-4"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature12506",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003823032",
"https://doi.org/10.1038/nature12506"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nm.3145",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004485531",
"https://doi.org/10.1038/nm.3145"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00125-018-4550-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1100691175",
"https://doi.org/10.1007/s00125-018-4550-1"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41467-019-11370-y",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1120286288",
"https://doi.org/10.1038/s41467-019-11370-y"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41588-019-0350-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1112198834",
"https://doi.org/10.1038/s41588-019-0350-x"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ncomms3469",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020010565",
"https://doi.org/10.1038/ncomms3469"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ncomms7734",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025453480",
"https://doi.org/10.1038/ncomms7734"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41575-019-0173-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1117918323",
"https://doi.org/10.1038/s41575-019-0173-3"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41586-020-2269-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1127404191",
"https://doi.org/10.1038/s41586-020-2269-x"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature18646",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017924056",
"https://doi.org/10.1038/nature18646"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nm.2307",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002009671",
"https://doi.org/10.1038/nm.2307"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41586-019-1065-y",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1113011488",
"https://doi.org/10.1038/s41586-019-1065-y"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41467-019-14177-z",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1124147887",
"https://doi.org/10.1038/s41467-019-14177-z"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.ijo.0801126",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002350830",
"https://doi.org/10.1038/sj.ijo.0801126"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ijo.2011.27",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029955377",
"https://doi.org/10.1038/ijo.2011.27"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41467-017-00900-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1092092284",
"https://doi.org/10.1038/s41467-017-00900-1"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature12480",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000291686",
"https://doi.org/10.1038/nature12480"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41564-018-0143-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1103565819",
"https://doi.org/10.1038/s41564-018-0143-5"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature09922",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043309820",
"https://doi.org/10.1038/nature09922"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nm.3994",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032893649",
"https://doi.org/10.1038/nm.3994"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41598-017-17765-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1100172290",
"https://doi.org/10.1038/s41598-017-17765-5"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature11450",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004546178",
"https://doi.org/10.1038/nature11450"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00125-019-4848-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1112964833",
"https://doi.org/10.1007/s00125-019-4848-7"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature15766",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014535385",
"https://doi.org/10.1038/nature15766"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41522-017-0039-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1092580968",
"https://doi.org/10.1038/s41522-017-0039-9"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41586-018-0353-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1105646346",
"https://doi.org/10.1038/s41586-018-0353-2"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature13568",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042881212",
"https://doi.org/10.1038/nature13568"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00253-001-0902-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047387939",
"https://doi.org/10.1007/s00253-001-0902-7"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature11234",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007740093",
"https://doi.org/10.1038/nature11234"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nmicrobiol.2016.93",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023953929",
"https://doi.org/10.1038/nmicrobiol.2016.93"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41467-018-07019-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1107954773",
"https://doi.org/10.1038/s41467-018-07019-x"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ismej.2012.146",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010887359",
"https://doi.org/10.1038/ismej.2012.146"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature12198",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002791386",
"https://doi.org/10.1038/nature12198"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nm.4345",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1085459595",
"https://doi.org/10.1038/nm.4345"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/tp.2014.98",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039300406",
"https://doi.org/10.1038/tp.2014.98"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nm.4236",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011574767",
"https://doi.org/10.1038/nm.4236"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s40168-018-0472-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1104000205",
"https://doi.org/10.1186/s40168-018-0472-x"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature08530",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020803808",
"https://doi.org/10.1038/nature08530"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature11053",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052378845",
"https://doi.org/10.1038/nature11053"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nmeth.3589",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028162909",
"https://doi.org/10.1038/nmeth.3589"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ni1018",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024411764",
"https://doi.org/10.1038/ni1018"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature24460",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1092687907",
"https://doi.org/10.1038/nature24460"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature05414",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023893418",
"https://doi.org/10.1038/nature05414"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41591-018-0222-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1107871640",
"https://doi.org/10.1038/s41591-018-0222-4"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/srep08096",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052381018",
"https://doi.org/10.1038/srep08096"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrendo.2017.151",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1099620162",
"https://doi.org/10.1038/nrendo.2017.151"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature23874",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1091381214",
"https://doi.org/10.1038/nature23874"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ijo.2016.46",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042938568",
"https://doi.org/10.1038/ijo.2016.46"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s13073-016-0300-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039049100",
"https://doi.org/10.1186/s13073-016-0300-5"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrgastro.2012.156",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002173942",
"https://doi.org/10.1038/nrgastro.2012.156"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature11986",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051643661",
"https://doi.org/10.1038/nature11986"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1111/j.1572-0241.2001.03702.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008626091",
"https://doi.org/10.1111/j.1572-0241.2001.03702.x"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41591-018-0061-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1105100677",
"https://doi.org/10.1038/s41591-018-0061-3"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41574-019-0156-z",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1111596982",
"https://doi.org/10.1038/s41574-019-0156-z"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ijo.2015.129",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031151094",
"https://doi.org/10.1038/ijo.2015.129"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41591-019-0495-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1117655252",
"https://doi.org/10.1038/s41591-019-0495-2"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41586-019-1236-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1115985307",
"https://doi.org/10.1038/s41586-019-1236-x"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/361362a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031441956",
"https://doi.org/10.1038/361362a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nm.4358",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1086072554",
"https://doi.org/10.1038/nm.4358"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41467-019-13721-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1123539228",
"https://doi.org/10.1038/s41467-019-13721-1"
],
"type": "CreativeWork"
}
],
"datePublished": "2020-09-04",
"datePublishedReg": "2020-09-04",
"description": "Observational findings achieved during the past two decades suggest that the intestinal microbiota may contribute to the metabolic health of the human host and, when aberrant, to the pathogenesis of various common metabolic disorders including obesity, type 2 diabetes, non-alcoholic liver disease, cardio-metabolic diseases and malnutrition. However, to gain a mechanistic understanding of how the gut microbiota affects host metabolism, research is moving from descriptive microbiota census analyses to cause-and-effect studies. Joint analyses of high-throughput human multi-omics data, including metagenomics and metabolomics data, together with measures of host physiology and mechanistic experiments in humans, animals and cells hold potential as initial steps in the identification of potential molecular mechanisms behind reported associations. In this Review, we discuss the current knowledge on how gut microbiota and derived microbial compounds may link to metabolism of the healthy host or to the pathogenesis of common metabolic diseases. We highlight examples of microbiota-targeted interventions aiming to optimize metabolic health, and we provide perspectives for future basic and translational investigations within the nascent and promising research field.",
"genre": "article",
"id": "sg:pub.10.1038/s41579-020-0433-9",
"isAccessibleForFree": true,
"isFundedItemOf": [
{
"id": "sg:grant.7571497",
"type": "MonetaryGrant"
}
],
"isPartOf": [
{
"id": "sg:journal.1032854",
"issn": [
"1740-1526",
"1740-1534"
],
"name": "Nature Reviews Microbiology",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "19"
}
],
"keywords": [
"metabolic health",
"gut microbiota",
"multi-omics data",
"non-alcoholic liver disease",
"potential molecular mechanisms",
"microbiota-targeted interventions",
"human metabolic health",
"common metabolic disorder",
"host physiology",
"type 2 diabetes",
"cardio-metabolic diseases",
"molecular mechanisms",
"common metabolic disease",
"microbial compounds",
"host metabolism",
"mechanistic understanding",
"human host",
"liver disease",
"metabolic disorders",
"intestinal microbiota",
"metabolic diseases",
"translational investigations",
"current knowledge",
"metabolomics data",
"disease",
"healthy hosts",
"microbiota",
"host",
"pathogenesis",
"metabolism",
"initial step",
"health",
"metagenomics",
"mechanistic experiments",
"obesity",
"physiology",
"diabetes",
"observational findings",
"joint analysis",
"nascent",
"malnutrition",
"disorders",
"cells",
"intervention",
"association",
"animals",
"identification",
"promising research field",
"humans",
"review",
"mechanism",
"findings",
"data",
"analysis",
"understanding",
"study",
"research field",
"measures",
"compounds",
"step",
"effect studies",
"knowledge",
"experiments",
"investigation",
"decades",
"census analysis",
"research",
"example",
"perspective",
"field"
],
"name": "Gut microbiota in human metabolic health and disease",
"pagination": "55-71",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1130573371"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/s41579-020-0433-9"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"32887946"
]
}
],
"sameAs": [
"https://doi.org/10.1038/s41579-020-0433-9",
"https://app.dimensions.ai/details/publication/pub.1130573371"
],
"sdDataset": "articles",
"sdDatePublished": "2022-08-04T17:10",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220804/entities/gbq_results/article/article_872.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1038/s41579-020-0433-9"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41579-020-0433-9'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41579-020-0433-9'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41579-020-0433-9'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41579-020-0433-9'
This table displays all metadata directly associated to this object as RDF triples.
472 TRIPLES
21 PREDICATES
178 URIs
95 LITERALS
15 BLANK NODES