The evolution of Zika virus from Asia to the Americas View Full Text


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Article Info

DATE

2019-01-07

AUTHORS

Zhong-Yu Liu, Wei-Feng Shi, Cheng-Feng Qin

ABSTRACT

Zika virus (ZIKV) was once considered an obscure member of the large and diverse family of mosquito-borne flaviviruses, and human infections with ZIKV were thought to be sporadic, with mild and self-limiting symptoms. The large-scale ZIKV epidemics in the Americas and the unexpected uncovering of a link to congenital birth defects escalated ZIKV infections to the status of a global public health emergency. Recent studies that combined reverse genetics with modelling in multiple systems have provided evidence that ZIKV has acquired additional amino acid substitutions at the same time as congenital Zika syndrome and other birth defects were detected. In this Progress article, we summarize the evolution of ZIKV during its spread from Asia to the Americas and discuss potential links to pathogenesis. More... »

PAGES

131-139

References to SciGraph publications

  • 2015-11-26. A report on the outbreak of Zika virus on Easter Island, South Pacific, 2014 in ARCHIVES OF VIROLOGY
  • 2017-02-15. A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in Vitro in SCIENTIFIC REPORTS
  • 2017-11-28. Pathogen genomic surveillance elucidates the origins, transmission and evolution of emerging viral agents in China in SCIENCE CHINA LIFE SCIENCES
  • 2017-08-09. Whole-genome sequence analysis of Zika virus, amplified from urine of traveler from the Philippines in VIRUS GENES
  • 2016-07-11. Structure of NS3 helicase from Zika virus in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2018-07-12. Negligible contribution of M2634V substitution to ZIKV pathogenesis in AG6 mice revealed by a bacterial promoter activity reduced infectious clone in SCIENTIFIC REPORTS
  • 2013-01-16. West Nile virus infection and immunity in NATURE REVIEWS MICROBIOLOGY
  • 2016-06-20. Flavivirus NS1 protein in infected host sera enhances viral acquisition by mosquitoes in NATURE MICROBIOLOGY
  • 2017-01-09. Structure of the immature Zika virus at 9 Å resolution in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2013-05-08. Barriers to preclinical investigations of anti-dengue immunity and dengue pathogenesis in NATURE REVIEWS MICROBIOLOGY
  • 2017-05-24. Genomic epidemiology reveals multiple introductions of Zika virus into the United States in NATURE
  • 2017-05-24. Establishment and cryptic transmission of Zika virus in Brazil and the Americas in NATURE
  • 2017-05-24. Zika virus evolution and spread in the Americas in NATURE
  • 2017-03-27. Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase in NATURE COMMUNICATIONS
  • 2018-01-29. An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction in NATURE COMMUNICATIONS
  • 2007-08-12. A single positively selected West Nile viral mutation confers increased virogenesis in American crows in NATURE GENETICS
  • 2016-07-18. Structural basis of Zika virus helicase in recognizing its substrates in PROTEIN & CELL
  • 2014-06-16. Functional long-range RNA–RNA interactions in positive-strand RNA viruses in NATURE REVIEWS MICROBIOLOGY
  • 2016-11-15. Structure of the NS2B-NS3 protease from Zika virus after self-cleavage in NATURE COMMUNICATIONS
  • 2017-04-07. Viral and serological kinetics in Zika virus-infected patients in South Korea in VIROLOGY JOURNAL
  • 2018-07-02. Miscarriage and Stillbirth Following Maternal Zika Virus Infection in Nonhuman Primates in NATURE MEDICINE
  • 2017-05-17. Evolutionary enhancement of Zika virus infectivity in Aedes aegypti mosquitoes in NATURE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/s41579-018-0134-9

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