Gastrointestinal motility, dysbiosis and opioid-induced tolerance: is there a link? View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-04-25

AUTHORS

Hamid I. Akbarali, William L. Dewey

ABSTRACT

Studies show that gut microbial dysbiosis induced by chronic opioid use is linked to central opioid tolerance. Here, we suggest that a persistent decrease in gastrointestinal motility by opioids is a primary cause of gut microbial dysbiosis and that improving gastrointestinal transit might be a strategy in preventing opioid analgesic tolerance. More... »

PAGES

323-324

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41575-019-0150-x

DOI

http://dx.doi.org/10.1038/s41575-019-0150-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1113707827

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/31024090


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