Gut microbial biofilm composition and organisation holds the key to CRC View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-04-30

AUTHORS

Georgina L. Hold, Emma Allen-Vercoe

ABSTRACT

A new study provides mechanistic insight into the carcinogenic potential of human colonic mucosal microbial biofilms, confirming that both microbiota composition and organization along with the host inflammatory response are contributing factors to creating the ‘perfect storm’ in terms of colorectal carcinogenesis.

PAGES

329-330

References to SciGraph publications

  • <error retrieving object. in <ERROR RETRIEVING OBJECT
  • 2014-09-08. The gut microbiota, bacterial metabolites and colorectal cancer in NATURE REVIEWS MICROBIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/s41575-019-0148-4

    DOI

    http://dx.doi.org/10.1038/s41575-019-0148-4

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1113837586

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/31040399


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Clinical Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Biofilms", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Colonic Neoplasms", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Gastrointestinal Microbiome", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Intestinal Mucosa", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Microbiome Research Centre, St George and Sutherland Clinical School, University of New South Wales, Sydney, New South Wales, Australia", 
              "id": "http://www.grid.ac/institutes/grid.1005.4", 
              "name": [
                "Microbiome Research Centre, St George and Sutherland Clinical School, University of New South Wales, Sydney, New South Wales, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hold", 
            "givenName": "Georgina L.", 
            "id": "sg:person.01015442527.89", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015442527.89"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada", 
              "id": "http://www.grid.ac/institutes/grid.34429.38", 
              "name": [
                "Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Allen-Vercoe", 
            "givenName": "Emma", 
            "id": "sg:person.01175752434.64", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175752434.64"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/nrc3245", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034518617", 
              "https://doi.org/10.1038/nrc3245"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrmicro3344", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045936127", 
              "https://doi.org/10.1038/nrmicro3344"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2019-04-30", 
        "datePublishedReg": "2019-04-30", 
        "description": "A new study provides mechanistic insight into the carcinogenic potential of human colonic mucosal microbial biofilms, confirming that both microbiota composition and organization along with the host inflammatory response are\u00a0contributing factors to creating the \u2018perfect storm\u2019 in terms of colorectal carcinogenesis.", 
        "genre": "article", 
        "id": "sg:pub.10.1038/s41575-019-0148-4", 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1294865", 
            "issn": [
              "1759-5045", 
              "1759-5053"
            ], 
            "name": "Nature Reviews Gastroenterology & Hepatology", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "6", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "16"
          }
        ], 
        "keywords": [
          "host inflammatory response", 
          "inflammatory response", 
          "colorectal carcinogenesis", 
          "microbiota composition", 
          "carcinogenic potential", 
          "new studies", 
          "CRC", 
          "carcinogenesis", 
          "mechanistic insights", 
          "biofilm composition", 
          "microbial biofilm composition", 
          "perfect storm", 
          "response", 
          "microbial biofilms", 
          "factors", 
          "study", 
          "biofilms", 
          "potential", 
          "organization", 
          "insights", 
          "composition", 
          "terms", 
          "key", 
          "storms"
        ], 
        "name": "Gut microbial biofilm composition and organisation holds the key to CRC", 
        "pagination": "329-330", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1113837586"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/s41575-019-0148-4"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "31040399"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/s41575-019-0148-4", 
          "https://app.dimensions.ai/details/publication/pub.1113837586"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-11-24T21:04", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20221124/entities/gbq_results/article/article_812.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1038/s41575-019-0148-4"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41575-019-0148-4'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41575-019-0148-4'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41575-019-0148-4'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41575-019-0148-4'


     

    This table displays all metadata directly associated to this object as RDF triples.

    123 TRIPLES      21 PREDICATES      56 URIs      46 LITERALS      12 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/s41575-019-0148-4 schema:about N7554073614bb419892f119b280d3b24c
    2 N8f9259184445459e8d7305c6018d92d4
    3 N9120c59f288c4cacada9da39291270fd
    4 Na8d95732b7c749dfbe2cb0481af356de
    5 Nef48644e7e814290822fff06adaa2f1b
    6 anzsrc-for:11
    7 anzsrc-for:1103
    8 schema:author N0e1459fd1111415f9879a1814ea898dc
    9 schema:citation sg:pub.10.1038/nrc3245
    10 sg:pub.10.1038/nrmicro3344
    11 schema:datePublished 2019-04-30
    12 schema:datePublishedReg 2019-04-30
    13 schema:description A new study provides mechanistic insight into the carcinogenic potential of human colonic mucosal microbial biofilms, confirming that both microbiota composition and organization along with the host inflammatory response are contributing factors to creating the ‘perfect storm’ in terms of colorectal carcinogenesis.
    14 schema:genre article
    15 schema:isAccessibleForFree false
    16 schema:isPartOf N187e707546894b0dbc61168b6bbb168c
    17 N6fcfb21e74ed416eba49af85639905fb
    18 sg:journal.1294865
    19 schema:keywords CRC
    20 biofilm composition
    21 biofilms
    22 carcinogenesis
    23 carcinogenic potential
    24 colorectal carcinogenesis
    25 composition
    26 factors
    27 host inflammatory response
    28 inflammatory response
    29 insights
    30 key
    31 mechanistic insights
    32 microbial biofilm composition
    33 microbial biofilms
    34 microbiota composition
    35 new studies
    36 organization
    37 perfect storm
    38 potential
    39 response
    40 storms
    41 study
    42 terms
    43 schema:name Gut microbial biofilm composition and organisation holds the key to CRC
    44 schema:pagination 329-330
    45 schema:productId N00fc666389cb4d48bfb4e7d143398afb
    46 N17df22271b2442a3babef4a9ec93bf50
    47 Nffcff87001844ceca98461ec4167df46
    48 schema:sameAs https://app.dimensions.ai/details/publication/pub.1113837586
    49 https://doi.org/10.1038/s41575-019-0148-4
    50 schema:sdDatePublished 2022-11-24T21:04
    51 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    52 schema:sdPublisher N28141caa18bc488285835432abe9361b
    53 schema:url https://doi.org/10.1038/s41575-019-0148-4
    54 sgo:license sg:explorer/license/
    55 sgo:sdDataset articles
    56 rdf:type schema:ScholarlyArticle
    57 N00fc666389cb4d48bfb4e7d143398afb schema:name dimensions_id
    58 schema:value pub.1113837586
    59 rdf:type schema:PropertyValue
    60 N0e1459fd1111415f9879a1814ea898dc rdf:first sg:person.01015442527.89
    61 rdf:rest N2a79aabcc5b74783b17292d2da60a4f6
    62 N17df22271b2442a3babef4a9ec93bf50 schema:name doi
    63 schema:value 10.1038/s41575-019-0148-4
    64 rdf:type schema:PropertyValue
    65 N187e707546894b0dbc61168b6bbb168c schema:issueNumber 6
    66 rdf:type schema:PublicationIssue
    67 N28141caa18bc488285835432abe9361b schema:name Springer Nature - SN SciGraph project
    68 rdf:type schema:Organization
    69 N2a79aabcc5b74783b17292d2da60a4f6 rdf:first sg:person.01175752434.64
    70 rdf:rest rdf:nil
    71 N6fcfb21e74ed416eba49af85639905fb schema:volumeNumber 16
    72 rdf:type schema:PublicationVolume
    73 N7554073614bb419892f119b280d3b24c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    74 schema:name Humans
    75 rdf:type schema:DefinedTerm
    76 N8f9259184445459e8d7305c6018d92d4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    77 schema:name Biofilms
    78 rdf:type schema:DefinedTerm
    79 N9120c59f288c4cacada9da39291270fd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    80 schema:name Gastrointestinal Microbiome
    81 rdf:type schema:DefinedTerm
    82 Na8d95732b7c749dfbe2cb0481af356de schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    83 schema:name Colonic Neoplasms
    84 rdf:type schema:DefinedTerm
    85 Nef48644e7e814290822fff06adaa2f1b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    86 schema:name Intestinal Mucosa
    87 rdf:type schema:DefinedTerm
    88 Nffcff87001844ceca98461ec4167df46 schema:name pubmed_id
    89 schema:value 31040399
    90 rdf:type schema:PropertyValue
    91 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    92 schema:name Medical and Health Sciences
    93 rdf:type schema:DefinedTerm
    94 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
    95 schema:name Clinical Sciences
    96 rdf:type schema:DefinedTerm
    97 sg:journal.1294865 schema:issn 1759-5045
    98 1759-5053
    99 schema:name Nature Reviews Gastroenterology & Hepatology
    100 schema:publisher Springer Nature
    101 rdf:type schema:Periodical
    102 sg:person.01015442527.89 schema:affiliation grid-institutes:grid.1005.4
    103 schema:familyName Hold
    104 schema:givenName Georgina L.
    105 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015442527.89
    106 rdf:type schema:Person
    107 sg:person.01175752434.64 schema:affiliation grid-institutes:grid.34429.38
    108 schema:familyName Allen-Vercoe
    109 schema:givenName Emma
    110 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175752434.64
    111 rdf:type schema:Person
    112 sg:pub.10.1038/nrc3245 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034518617
    113 https://doi.org/10.1038/nrc3245
    114 rdf:type schema:CreativeWork
    115 sg:pub.10.1038/nrmicro3344 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045936127
    116 https://doi.org/10.1038/nrmicro3344
    117 rdf:type schema:CreativeWork
    118 grid-institutes:grid.1005.4 schema:alternateName Microbiome Research Centre, St George and Sutherland Clinical School, University of New South Wales, Sydney, New South Wales, Australia
    119 schema:name Microbiome Research Centre, St George and Sutherland Clinical School, University of New South Wales, Sydney, New South Wales, Australia
    120 rdf:type schema:Organization
    121 grid-institutes:grid.34429.38 schema:alternateName Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada
    122 schema:name Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada
    123 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...