Searching for superstool: maximizing the therapeutic potential of FMT View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-07

AUTHORS

Scott W. Olesen, McKenzie M. Leier, Eric J. Alm, Stacy A. Kahn

ABSTRACT

Faecal microbiota transplantation (FMT), a highly effective treatment for Clostridium difficile infection, is now being explored for complex diseases, but innovative trial design and collaborative approaches are essential for unlocking its therapeutic potential. If ‘superstool’ capable of treating a complex disease exists, then FMT trials should aim to find and use it. More... »

PAGES

387-388

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41575-018-0019-4

DOI

http://dx.doi.org/10.1038/s41575-018-0019-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1103657965

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29703976


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Immunology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Massachusetts Institute of Technology", 
          "id": "https://www.grid.ac/institutes/grid.116068.8", 
          "name": [
            "Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Olesen", 
        "givenName": "Scott W.", 
        "id": "sg:person.0710662507.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710662507.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Boston Children's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.2515.3", 
          "name": [
            "Boston Children\u2019s Hospital, Division of Gastroenterology and Nutrition, Inflammatory Bowel Disease Center, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Leier", 
        "givenName": "McKenzie M.", 
        "id": "sg:person.015717451742.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015717451742.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Broad Institute", 
          "id": "https://www.grid.ac/institutes/grid.66859.34", 
          "name": [
            "Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA", 
            "Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA, USA", 
            "The Broad Institute of MIT and Harvard, Cambridge, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Alm", 
        "givenName": "Eric J.", 
        "id": "sg:person.0622302463.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622302463.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Harvard University", 
          "id": "https://www.grid.ac/institutes/grid.38142.3c", 
          "name": [
            "Boston Children\u2019s Hospital, Division of Gastroenterology and Nutrition, Inflammatory Bowel Disease Center, Boston, MA, USA", 
            "Harvard Medical School, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kahn", 
        "givenName": "Stacy A.", 
        "id": "sg:person.01133767323.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01133767323.44"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1053/j.gastro.2016.11.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006158946"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature06244", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009917183", 
          "https://doi.org/10.1038/nature06244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jcm.00820-15", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028318285"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.gastro.2015.04.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037628599"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.2015.2316", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045425556"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ajg.2013.59", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045998193", 
          "https://doi.org/10.1038/ajg.2013.59"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0962280216688502", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083734963"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0962280216688502", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083734963"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmra1510062", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090361612"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mib.0000000000001247", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091409235"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mib.0000000000001247", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091409235"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mib.0000000000001247", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091409235"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-07", 
    "datePublishedReg": "2018-07-01", 
    "description": "Faecal microbiota transplantation (FMT), a highly effective treatment for Clostridium difficile infection, is now being explored for complex diseases, but innovative trial design and collaborative approaches are essential for unlocking its therapeutic potential. If \u2018superstool\u2019 capable of treating a complex disease exists, then FMT trials should aim to find and use it.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/s41575-018-0019-4", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1294865", 
        "issn": [
          "1759-5045", 
          "1759-5053"
        ], 
        "name": "Nature Reviews Gastroenterology & Hepatology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "7", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "15"
      }
    ], 
    "name": "Searching for superstool: maximizing the therapeutic potential of FMT", 
    "pagination": "387-388", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "1cad0fe472730bb32ca311112b3223ba2546ff5f51aaf6c34248843b99e498ba"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "29703976"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101500079"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s41575-018-0019-4"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1103657965"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s41575-018-0019-4", 
      "https://app.dimensions.ai/details/publication/pub.1103657965"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T20:43", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8684_00000493.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/s41575-018-0019-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41575-018-0019-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41575-018-0019-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41575-018-0019-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41575-018-0019-4'


 

This table displays all metadata directly associated to this object as RDF triples.

131 TRIPLES      21 PREDICATES      38 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s41575-018-0019-4 schema:about anzsrc-for:11
2 anzsrc-for:1107
3 schema:author N5b73cd42118a409f8ad30eb323decd64
4 schema:citation sg:pub.10.1038/ajg.2013.59
5 sg:pub.10.1038/nature06244
6 https://doi.org/10.1001/jama.2015.2316
7 https://doi.org/10.1053/j.gastro.2015.04.001
8 https://doi.org/10.1053/j.gastro.2016.11.010
9 https://doi.org/10.1056/nejmra1510062
10 https://doi.org/10.1097/mib.0000000000001247
11 https://doi.org/10.1128/jcm.00820-15
12 https://doi.org/10.1177/0962280216688502
13 schema:datePublished 2018-07
14 schema:datePublishedReg 2018-07-01
15 schema:description Faecal microbiota transplantation (FMT), a highly effective treatment for Clostridium difficile infection, is now being explored for complex diseases, but innovative trial design and collaborative approaches are essential for unlocking its therapeutic potential. If ‘superstool’ capable of treating a complex disease exists, then FMT trials should aim to find and use it.
16 schema:genre research_article
17 schema:inLanguage en
18 schema:isAccessibleForFree false
19 schema:isPartOf N525c86edcdcd474b8df8f6338a9ba7be
20 N5e5320e501b94ca6baecf8fe1ea1fb79
21 sg:journal.1294865
22 schema:name Searching for superstool: maximizing the therapeutic potential of FMT
23 schema:pagination 387-388
24 schema:productId N0f50c5a8e30843c2883aba4c84199d73
25 N17e1a36fe33b452892b60b0064d474e7
26 N78402f6906804c0c8bc67de59475237f
27 Na9c77b4d8af746378806d76d986500a4
28 Naf04894d9c454b5fa95e74d4fd28db39
29 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103657965
30 https://doi.org/10.1038/s41575-018-0019-4
31 schema:sdDatePublished 2019-04-10T20:43
32 schema:sdLicense https://scigraph.springernature.com/explorer/license/
33 schema:sdPublisher Ne4cb39cd787b4947bfe0195bb51f0bfa
34 schema:url https://www.nature.com/articles/s41575-018-0019-4
35 sgo:license sg:explorer/license/
36 sgo:sdDataset articles
37 rdf:type schema:ScholarlyArticle
38 N0f50c5a8e30843c2883aba4c84199d73 schema:name readcube_id
39 schema:value 1cad0fe472730bb32ca311112b3223ba2546ff5f51aaf6c34248843b99e498ba
40 rdf:type schema:PropertyValue
41 N17e1a36fe33b452892b60b0064d474e7 schema:name pubmed_id
42 schema:value 29703976
43 rdf:type schema:PropertyValue
44 N3d92c88c52244cc18eccf3c93f89f7bf rdf:first sg:person.0622302463.69
45 rdf:rest Naee37bed709a4246b93296f8b63f1c5b
46 N525c86edcdcd474b8df8f6338a9ba7be schema:issueNumber 7
47 rdf:type schema:PublicationIssue
48 N5b73cd42118a409f8ad30eb323decd64 rdf:first sg:person.0710662507.49
49 rdf:rest N99f6fa199aa6470eb54ce18c0c191409
50 N5e5320e501b94ca6baecf8fe1ea1fb79 schema:volumeNumber 15
51 rdf:type schema:PublicationVolume
52 N78402f6906804c0c8bc67de59475237f schema:name doi
53 schema:value 10.1038/s41575-018-0019-4
54 rdf:type schema:PropertyValue
55 N99f6fa199aa6470eb54ce18c0c191409 rdf:first sg:person.015717451742.06
56 rdf:rest N3d92c88c52244cc18eccf3c93f89f7bf
57 Na9c77b4d8af746378806d76d986500a4 schema:name dimensions_id
58 schema:value pub.1103657965
59 rdf:type schema:PropertyValue
60 Naee37bed709a4246b93296f8b63f1c5b rdf:first sg:person.01133767323.44
61 rdf:rest rdf:nil
62 Naf04894d9c454b5fa95e74d4fd28db39 schema:name nlm_unique_id
63 schema:value 101500079
64 rdf:type schema:PropertyValue
65 Ne4cb39cd787b4947bfe0195bb51f0bfa schema:name Springer Nature - SN SciGraph project
66 rdf:type schema:Organization
67 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
68 schema:name Medical and Health Sciences
69 rdf:type schema:DefinedTerm
70 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
71 schema:name Immunology
72 rdf:type schema:DefinedTerm
73 sg:journal.1294865 schema:issn 1759-5045
74 1759-5053
75 schema:name Nature Reviews Gastroenterology & Hepatology
76 rdf:type schema:Periodical
77 sg:person.01133767323.44 schema:affiliation https://www.grid.ac/institutes/grid.38142.3c
78 schema:familyName Kahn
79 schema:givenName Stacy A.
80 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01133767323.44
81 rdf:type schema:Person
82 sg:person.015717451742.06 schema:affiliation https://www.grid.ac/institutes/grid.2515.3
83 schema:familyName Leier
84 schema:givenName McKenzie M.
85 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015717451742.06
86 rdf:type schema:Person
87 sg:person.0622302463.69 schema:affiliation https://www.grid.ac/institutes/grid.66859.34
88 schema:familyName Alm
89 schema:givenName Eric J.
90 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622302463.69
91 rdf:type schema:Person
92 sg:person.0710662507.49 schema:affiliation https://www.grid.ac/institutes/grid.116068.8
93 schema:familyName Olesen
94 schema:givenName Scott W.
95 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710662507.49
96 rdf:type schema:Person
97 sg:pub.10.1038/ajg.2013.59 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045998193
98 https://doi.org/10.1038/ajg.2013.59
99 rdf:type schema:CreativeWork
100 sg:pub.10.1038/nature06244 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009917183
101 https://doi.org/10.1038/nature06244
102 rdf:type schema:CreativeWork
103 https://doi.org/10.1001/jama.2015.2316 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045425556
104 rdf:type schema:CreativeWork
105 https://doi.org/10.1053/j.gastro.2015.04.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037628599
106 rdf:type schema:CreativeWork
107 https://doi.org/10.1053/j.gastro.2016.11.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006158946
108 rdf:type schema:CreativeWork
109 https://doi.org/10.1056/nejmra1510062 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090361612
110 rdf:type schema:CreativeWork
111 https://doi.org/10.1097/mib.0000000000001247 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091409235
112 rdf:type schema:CreativeWork
113 https://doi.org/10.1128/jcm.00820-15 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028318285
114 rdf:type schema:CreativeWork
115 https://doi.org/10.1177/0962280216688502 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083734963
116 rdf:type schema:CreativeWork
117 https://www.grid.ac/institutes/grid.116068.8 schema:alternateName Massachusetts Institute of Technology
118 schema:name Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
119 rdf:type schema:Organization
120 https://www.grid.ac/institutes/grid.2515.3 schema:alternateName Boston Children's Hospital
121 schema:name Boston Children’s Hospital, Division of Gastroenterology and Nutrition, Inflammatory Bowel Disease Center, Boston, MA, USA
122 rdf:type schema:Organization
123 https://www.grid.ac/institutes/grid.38142.3c schema:alternateName Harvard University
124 schema:name Boston Children’s Hospital, Division of Gastroenterology and Nutrition, Inflammatory Bowel Disease Center, Boston, MA, USA
125 Harvard Medical School, Boston, MA, USA
126 rdf:type schema:Organization
127 https://www.grid.ac/institutes/grid.66859.34 schema:alternateName Broad Institute
128 schema:name Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA, USA
129 Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
130 The Broad Institute of MIT and Harvard, Cambridge, MA, USA
131 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...