Obesity: global epidemiology and pathogenesis View Full Text


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Article Info

DATE

2019-05

AUTHORS

Matthias Blüher

ABSTRACT

The prevalence of obesity has increased worldwide in the past ~50 years, reaching pandemic levels. Obesity represents a major health challenge because it substantially increases the risk of diseases such as type 2 diabetes mellitus, fatty liver disease, hypertension, myocardial infarction, stroke, dementia, osteoarthritis, obstructive sleep apnoea and several cancers, thereby contributing to a decline in both quality of life and life expectancy. Obesity is also associated with unemployment, social disadvantages and reduced socio-economic productivity, thus increasingly creating an economic burden. Thus far, obesity prevention and treatment strategies - both at the individual and population level - have not been successful in the long term. Lifestyle and behavioural interventions aimed at reducing calorie intake and increasing energy expenditure have limited effectiveness because complex and persistent hormonal, metabolic and neurochemical adaptations defend against weight loss and promote weight regain. Reducing the obesity burden requires approaches that combine individual interventions with changes in the environment and society. Therefore, a better understanding of the remarkable regional differences in obesity prevalence and trends might help to identify societal causes of obesity and provide guidance on which are the most promising intervention strategies. More... »

PAGES

1

References to SciGraph publications

  • 1997-06. Congenital leptin deficiency is associated with severe early-onset obesity in humans in NATURE
  • 2013-08. The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry in NATURE NEUROSCIENCE
  • 2015-12. Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence in CLINICAL EPIGENETICS
  • 2014-09. Hormonal and neural mechanisms of food reward, eating behaviour and obesity in NATURE REVIEWS ENDOCRINOLOGY
  • 2017-01. Television food advertisement exposure and FTO rs9939609 genotype in relation to excess consumption in children in INTERNATIONAL JOURNAL OF OBESITY
  • 2014-01. The bigger picture of FTO—the first GWAS-identified obesity gene in NATURE REVIEWS ENDOCRINOLOGY
  • 2009-04. Why inequality is fatal in NATURE
  • 2015-08. Cognitive and autonomic determinants of energy homeostasis in obesity in NATURE REVIEWS ENDOCRINOLOGY
  • 1998-06. Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans in NATURE GENETICS
  • 2000-04. Obesity as a medical problem in NATURE
  • 1994-12. Positional cloning of the mouse obese gene and its human homologue in NATURE
  • 2017-11-24. Obesity: Trends in underweight and obesity — scale of the problem in NATURE REVIEWS ENDOCRINOLOGY
  • 2008-12. Rapid increases in obesity in Jamaica, compared to Nigeria and the United States in BMC PUBLIC HEALTH
  • 2018-02-22. Signalling from the periphery to the brain that regulates energy homeostasis in NATURE REVIEWS NEUROSCIENCE
  • 2018-12. Prevalence and associated factors of overweight/ obesity among children and adolescents in Ethiopia: a systematic review and meta-analysis in BMC OBESITY
  • 2013-12. Food availability of glucose and fat, but not fructose, increased in the US between 1970 and 2009: analysis of the USDA food availability data system in NUTRITION JOURNAL
  • 2018-06-28. Striatal Rgs4 regulates feeding and susceptibility to diet-induced obesity in MOLECULAR PSYCHIATRY
  • 2010-11. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index in NATURE GENETICS
  • 1998-03. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction in NATURE
  • 2018-07. Obesity and the future of food policies that promote healthy diets in NATURE REVIEWS ENDOCRINOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/s41574-019-0176-8

    DOI

    http://dx.doi.org/10.1038/s41574-019-0176-8

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1112395586

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30814686


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