Charge splitters and charge transport junctions based on guanine quadruplexes View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-04

AUTHORS

Ruojie Sha, Limin Xiang, Chaoren Liu, Alexander Balaeff, Yuqi Zhang, Peng Zhang, Yueqi Li, David N. Beratan, Nongjian Tao, Nadrian C. Seeman

ABSTRACT

Self-assembling circuit elements, such as current splitters or combiners at the molecular scale, require the design of building blocks with three or more terminals. A promising material for such building blocks is DNA, wherein multiple strands can self-assemble into multi-ended junctions, and nucleobase stacks can transport charge over long distances. However, nucleobase stacking is often disrupted at junction points, hindering electric charge transport between the two terminals of the junction. Here, we show that a guanine-quadruplex (G4) motif can be used as a connector element for a multi-ended DNA junction. By attaching specific terminal groups to the motif, we demonstrate that charges can enter the structure from one terminal at one end of a three-way G4 motif, and can exit from one of two terminals at the other end with minimal carrier transport attenuation. Moreover, we study four-way G4 junction structures by performing theoretical calculations to assist in the design and optimization of these connectors. More... »

PAGES

316-321

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41565-018-0070-x

DOI

http://dx.doi.org/10.1038/s41565-018-0070-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1101201670

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29483600


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0905", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Civil Engineering", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/09", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Engineering", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "New York University", 
          "id": "https://www.grid.ac/institutes/grid.137628.9", 
          "name": [
            "Department of Chemistry, New York University, New York, NY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sha", 
        "givenName": "Ruojie", 
        "id": "sg:person.0757372206.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757372206.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Arizona State University", 
          "id": "https://www.grid.ac/institutes/grid.215654.1", 
          "name": [
            "Biodesign Center for Biosensors and Bioelectronics, Biodesign Institute, Arizona State University, Tempe, AZ, USA", 
            "School of Molecular Sciences, Arizona State University, Tempe, AZ, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Xiang", 
        "givenName": "Limin", 
        "id": "sg:person.0763527330.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0763527330.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Duke University", 
          "id": "https://www.grid.ac/institutes/grid.26009.3d", 
          "name": [
            "Departments of Chemistry, Duke University, Durham, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Liu", 
        "givenName": "Chaoren", 
        "id": "sg:person.01060425732.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060425732.73"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Central Florida", 
          "id": "https://www.grid.ac/institutes/grid.170430.1", 
          "name": [
            "Departments of Chemistry, Duke University, Durham, NC, USA", 
            "Nanoscience Technology Center & Department of Physics, University of Central Florida, Orlando, FL, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Balaeff", 
        "givenName": "Alexander", 
        "id": "sg:person.01334373351.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01334373351.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Duke University", 
          "id": "https://www.grid.ac/institutes/grid.26009.3d", 
          "name": [
            "Departments of Chemistry, Duke University, Durham, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhang", 
        "givenName": "Yuqi", 
        "id": "sg:person.01235064371.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235064371.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Duke University", 
          "id": "https://www.grid.ac/institutes/grid.26009.3d", 
          "name": [
            "Departments of Chemistry, Duke University, Durham, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhang", 
        "givenName": "Peng", 
        "id": "sg:person.01342665754.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342665754.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Arizona State University", 
          "id": "https://www.grid.ac/institutes/grid.215654.1", 
          "name": [
            "Biodesign Center for Biosensors and Bioelectronics, Biodesign Institute, Arizona State University, Tempe, AZ, USA", 
            "School of Molecular Sciences, Arizona State University, Tempe, AZ, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Li", 
        "givenName": "Yueqi", 
        "id": "sg:person.01016737103.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016737103.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Duke University", 
          "id": "https://www.grid.ac/institutes/grid.26009.3d", 
          "name": [
            "Departments of Chemistry, Duke University, Durham, NC, USA", 
            "Department of Biochemistry, Duke University, Durham, NC, USA", 
            "Department of Physics, Duke University, Durham, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Beratan", 
        "givenName": "David N.", 
        "id": "sg:person.013163320522.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013163320522.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Arizona State University", 
          "id": "https://www.grid.ac/institutes/grid.215654.1", 
          "name": [
            "Biodesign Center for Biosensors and Bioelectronics, Biodesign Institute, Arizona State University, Tempe, AZ, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tao", 
        "givenName": "Nongjian", 
        "id": "sg:person.01151576226.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01151576226.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "New York University", 
          "id": "https://www.grid.ac/institutes/grid.137628.9", 
          "name": [
            "Department of Chemistry, New York University, New York, NY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Seeman", 
        "givenName": "Nadrian C.", 
        "id": "sg:person.01155412761.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155412761.86"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1146/annurev-biochem-060308-102244", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001467731"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.susc.2016.03.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009138080"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.susc.2016.03.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009138080"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.susc.2016.03.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009138080"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1063/1.3460132", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012034346"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1998.1875", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012732749"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35085542", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016059942", 
          "https://doi.org/10.1038/35085542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35085542", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016059942", 
          "https://doi.org/10.1038/35085542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nnano.2014.246", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016806675", 
          "https://doi.org/10.1038/nnano.2014.246"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1996.0157", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017094374"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/29.10.2026", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017858591"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja2076857", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018579720"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja2076857", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018579720"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/acs.chemrev.5b00298", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024367766"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c4fd00106k", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026097971"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/anie.201407729", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027976480"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0009-2614(75)80190-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028788082"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja065864k", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029863403"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja065864k", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029863403"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nchem.2545", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032245652", 
          "https://doi.org/10.1038/nchem.2545"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature01406", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033919453", 
          "https://doi.org/10.1038/nature01406"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature01406", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033919453", 
          "https://doi.org/10.1038/nature01406"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.95.22.12759", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035031498"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/128_2013_511", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038139466", 
          "https://doi.org/10.1007/128_2013_511"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nchem.2183", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039653945", 
          "https://doi.org/10.1038/nchem.2183"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jcc.20289", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040543339"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jcc.20289", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040543339"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.physchem.54.011002.103746", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042164744"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1074-5521(00)00133-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042717789"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.48.12.2013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047929716"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/cr900228f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053965454"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/cr900228f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053965454"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/acs.jpclett.5b00863", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055113806"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ar0000197", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055148121"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ar0000197", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055148121"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ar400079s", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055150389"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ar990040b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055152406"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ar990040b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055152406"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi9007484", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055209872"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi9007484", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055209872"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja0032632", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055723564"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja0032632", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055723564"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja9609821", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055864975"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja9609821", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055864975"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jacs.5b00931", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055873778"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jp001109w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056042900"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jp001109w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056042900"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jp110871g", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056080657"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jp110871g", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056080657"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jp404788t", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056095662"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jp512767j", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056104875"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jp9933323", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056132154"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jp9933323", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056132154"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/nl0494295", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056216060"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/nl0494295", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056216060"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1087481", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062448383"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.3863253", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062622013"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-04", 
    "datePublishedReg": "2018-04-01", 
    "description": "Self-assembling circuit elements, such as current splitters or combiners at the molecular scale, require the design of building blocks with three or more terminals. A promising material for such building blocks is DNA, wherein multiple strands can self-assemble into multi-ended junctions, and nucleobase stacks can transport charge over long distances. However, nucleobase stacking is often disrupted at junction points, hindering electric charge transport between the two terminals of the junction. Here, we show that a guanine-quadruplex (G4) motif can be used as a connector element for a multi-ended DNA junction. By attaching specific terminal groups to the motif, we demonstrate that charges can enter the structure from one terminal at one end of a three-way G4 motif, and can exit from one of two terminals at the other end with minimal carrier transport attenuation. Moreover, we study four-way G4 junction structures by performing theoretical calculations to assist in the design and optimization of these connectors.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/s41565-018-0070-x", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1037429", 
        "issn": [
          "1748-3387", 
          "1748-3395"
        ], 
        "name": "Nature Nanotechnology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "13"
      }
    ], 
    "name": "Charge splitters and charge transport junctions based on guanine quadruplexes", 
    "pagination": "316-321", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "e6375feecd4822e1ccf1dbcacf219fb2a5e58f9c74410b4d2cca1c07ecdff56e"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "29483600"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101283273"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s41565-018-0070-x"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1101201670"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s41565-018-0070-x", 
      "https://app.dimensions.ai/details/publication/pub.1101201670"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T10:04", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89826_00000003.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/s41565-018-0070-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41565-018-0070-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41565-018-0070-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41565-018-0070-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41565-018-0070-x'


 

This table displays all metadata directly associated to this object as RDF triples.

271 TRIPLES      21 PREDICATES      69 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s41565-018-0070-x schema:about anzsrc-for:09
2 anzsrc-for:0905
3 schema:author N12869a01c3254c9ca149555113e19f38
4 schema:citation sg:pub.10.1007/128_2013_511
5 sg:pub.10.1038/35085542
6 sg:pub.10.1038/nature01406
7 sg:pub.10.1038/nchem.2183
8 sg:pub.10.1038/nchem.2545
9 sg:pub.10.1038/nnano.2014.246
10 https://doi.org/10.1002/anie.201407729
11 https://doi.org/10.1002/jcc.20289
12 https://doi.org/10.1006/jmbi.1996.0157
13 https://doi.org/10.1006/jmbi.1998.1875
14 https://doi.org/10.1016/0009-2614(75)80190-4
15 https://doi.org/10.1016/j.susc.2016.03.011
16 https://doi.org/10.1016/s1074-5521(00)00133-2
17 https://doi.org/10.1021/acs.chemrev.5b00298
18 https://doi.org/10.1021/acs.jpclett.5b00863
19 https://doi.org/10.1021/ar0000197
20 https://doi.org/10.1021/ar400079s
21 https://doi.org/10.1021/ar990040b
22 https://doi.org/10.1021/bi9007484
23 https://doi.org/10.1021/cr900228f
24 https://doi.org/10.1021/ja0032632
25 https://doi.org/10.1021/ja065864k
26 https://doi.org/10.1021/ja2076857
27 https://doi.org/10.1021/ja9609821
28 https://doi.org/10.1021/jacs.5b00931
29 https://doi.org/10.1021/jp001109w
30 https://doi.org/10.1021/jp110871g
31 https://doi.org/10.1021/jp404788t
32 https://doi.org/10.1021/jp512767j
33 https://doi.org/10.1021/jp9933323
34 https://doi.org/10.1021/nl0494295
35 https://doi.org/10.1039/c4fd00106k
36 https://doi.org/10.1063/1.3460132
37 https://doi.org/10.1073/pnas.48.12.2013
38 https://doi.org/10.1073/pnas.95.22.12759
39 https://doi.org/10.1093/nar/29.10.2026
40 https://doi.org/10.1126/science.1087481
41 https://doi.org/10.1126/science.3863253
42 https://doi.org/10.1146/annurev-biochem-060308-102244
43 https://doi.org/10.1146/annurev.physchem.54.011002.103746
44 schema:datePublished 2018-04
45 schema:datePublishedReg 2018-04-01
46 schema:description Self-assembling circuit elements, such as current splitters or combiners at the molecular scale, require the design of building blocks with three or more terminals. A promising material for such building blocks is DNA, wherein multiple strands can self-assemble into multi-ended junctions, and nucleobase stacks can transport charge over long distances. However, nucleobase stacking is often disrupted at junction points, hindering electric charge transport between the two terminals of the junction. Here, we show that a guanine-quadruplex (G4) motif can be used as a connector element for a multi-ended DNA junction. By attaching specific terminal groups to the motif, we demonstrate that charges can enter the structure from one terminal at one end of a three-way G4 motif, and can exit from one of two terminals at the other end with minimal carrier transport attenuation. Moreover, we study four-way G4 junction structures by performing theoretical calculations to assist in the design and optimization of these connectors.
47 schema:genre research_article
48 schema:inLanguage en
49 schema:isAccessibleForFree false
50 schema:isPartOf N0f044d117a064e8297829a47cf248775
51 Naa4677dde0ac4143a7a7fa6976cdc752
52 sg:journal.1037429
53 schema:name Charge splitters and charge transport junctions based on guanine quadruplexes
54 schema:pagination 316-321
55 schema:productId N082c2a03a6b74c8384192c880770874a
56 N23967ed3862540a983f8c4107d0c7a09
57 N337722de51c849fd8d3b1f742e7f55fd
58 N5536791d7d7d469ba535fa6dcedd72a3
59 N6c1ebc0100304b7b90848dd1a286d4c6
60 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101201670
61 https://doi.org/10.1038/s41565-018-0070-x
62 schema:sdDatePublished 2019-04-11T10:04
63 schema:sdLicense https://scigraph.springernature.com/explorer/license/
64 schema:sdPublisher N15fe54784a5342988e4d824006e6ea97
65 schema:url https://www.nature.com/articles/s41565-018-0070-x
66 sgo:license sg:explorer/license/
67 sgo:sdDataset articles
68 rdf:type schema:ScholarlyArticle
69 N082c2a03a6b74c8384192c880770874a schema:name dimensions_id
70 schema:value pub.1101201670
71 rdf:type schema:PropertyValue
72 N0b79cc3af97c4a218e014e5f8ba17371 rdf:first sg:person.01342665754.00
73 rdf:rest N2f8d7eaceae54ce6935dd9f76d03d22a
74 N0f044d117a064e8297829a47cf248775 schema:volumeNumber 13
75 rdf:type schema:PublicationVolume
76 N12869a01c3254c9ca149555113e19f38 rdf:first sg:person.0757372206.78
77 rdf:rest Nbcd968d135ea474bae8bf52c169028f3
78 N15fe54784a5342988e4d824006e6ea97 schema:name Springer Nature - SN SciGraph project
79 rdf:type schema:Organization
80 N23967ed3862540a983f8c4107d0c7a09 schema:name nlm_unique_id
81 schema:value 101283273
82 rdf:type schema:PropertyValue
83 N25c23d1f72154e92bf31d0e34989dbb1 rdf:first sg:person.01060425732.73
84 rdf:rest N61ea9df892304bfe9aacd6771007d9f5
85 N2f8d7eaceae54ce6935dd9f76d03d22a rdf:first sg:person.01016737103.51
86 rdf:rest Nbd1281ee653e4eadacc53c4c6820f176
87 N32056490da7d431e8a2c43473f4753fd rdf:first sg:person.01235064371.03
88 rdf:rest N0b79cc3af97c4a218e014e5f8ba17371
89 N337722de51c849fd8d3b1f742e7f55fd schema:name pubmed_id
90 schema:value 29483600
91 rdf:type schema:PropertyValue
92 N5536791d7d7d469ba535fa6dcedd72a3 schema:name readcube_id
93 schema:value e6375feecd4822e1ccf1dbcacf219fb2a5e58f9c74410b4d2cca1c07ecdff56e
94 rdf:type schema:PropertyValue
95 N61ea9df892304bfe9aacd6771007d9f5 rdf:first sg:person.01334373351.61
96 rdf:rest N32056490da7d431e8a2c43473f4753fd
97 N6c1ebc0100304b7b90848dd1a286d4c6 schema:name doi
98 schema:value 10.1038/s41565-018-0070-x
99 rdf:type schema:PropertyValue
100 Na8d4fa8ffda1441cb3b7c9f3fb7f58c8 rdf:first sg:person.01155412761.86
101 rdf:rest rdf:nil
102 Naa4677dde0ac4143a7a7fa6976cdc752 schema:issueNumber 4
103 rdf:type schema:PublicationIssue
104 Nbcd968d135ea474bae8bf52c169028f3 rdf:first sg:person.0763527330.30
105 rdf:rest N25c23d1f72154e92bf31d0e34989dbb1
106 Nbd1281ee653e4eadacc53c4c6820f176 rdf:first sg:person.013163320522.01
107 rdf:rest Ne649a58c55714ba195615ae7d41c14fe
108 Ne649a58c55714ba195615ae7d41c14fe rdf:first sg:person.01151576226.01
109 rdf:rest Na8d4fa8ffda1441cb3b7c9f3fb7f58c8
110 anzsrc-for:09 schema:inDefinedTermSet anzsrc-for:
111 schema:name Engineering
112 rdf:type schema:DefinedTerm
113 anzsrc-for:0905 schema:inDefinedTermSet anzsrc-for:
114 schema:name Civil Engineering
115 rdf:type schema:DefinedTerm
116 sg:journal.1037429 schema:issn 1748-3387
117 1748-3395
118 schema:name Nature Nanotechnology
119 rdf:type schema:Periodical
120 sg:person.01016737103.51 schema:affiliation https://www.grid.ac/institutes/grid.215654.1
121 schema:familyName Li
122 schema:givenName Yueqi
123 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016737103.51
124 rdf:type schema:Person
125 sg:person.01060425732.73 schema:affiliation https://www.grid.ac/institutes/grid.26009.3d
126 schema:familyName Liu
127 schema:givenName Chaoren
128 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060425732.73
129 rdf:type schema:Person
130 sg:person.01151576226.01 schema:affiliation https://www.grid.ac/institutes/grid.215654.1
131 schema:familyName Tao
132 schema:givenName Nongjian
133 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01151576226.01
134 rdf:type schema:Person
135 sg:person.01155412761.86 schema:affiliation https://www.grid.ac/institutes/grid.137628.9
136 schema:familyName Seeman
137 schema:givenName Nadrian C.
138 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155412761.86
139 rdf:type schema:Person
140 sg:person.01235064371.03 schema:affiliation https://www.grid.ac/institutes/grid.26009.3d
141 schema:familyName Zhang
142 schema:givenName Yuqi
143 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235064371.03
144 rdf:type schema:Person
145 sg:person.013163320522.01 schema:affiliation https://www.grid.ac/institutes/grid.26009.3d
146 schema:familyName Beratan
147 schema:givenName David N.
148 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013163320522.01
149 rdf:type schema:Person
150 sg:person.01334373351.61 schema:affiliation https://www.grid.ac/institutes/grid.170430.1
151 schema:familyName Balaeff
152 schema:givenName Alexander
153 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01334373351.61
154 rdf:type schema:Person
155 sg:person.01342665754.00 schema:affiliation https://www.grid.ac/institutes/grid.26009.3d
156 schema:familyName Zhang
157 schema:givenName Peng
158 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342665754.00
159 rdf:type schema:Person
160 sg:person.0757372206.78 schema:affiliation https://www.grid.ac/institutes/grid.137628.9
161 schema:familyName Sha
162 schema:givenName Ruojie
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757372206.78
164 rdf:type schema:Person
165 sg:person.0763527330.30 schema:affiliation https://www.grid.ac/institutes/grid.215654.1
166 schema:familyName Xiang
167 schema:givenName Limin
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0763527330.30
169 rdf:type schema:Person
170 sg:pub.10.1007/128_2013_511 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038139466
171 https://doi.org/10.1007/128_2013_511
172 rdf:type schema:CreativeWork
173 sg:pub.10.1038/35085542 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016059942
174 https://doi.org/10.1038/35085542
175 rdf:type schema:CreativeWork
176 sg:pub.10.1038/nature01406 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033919453
177 https://doi.org/10.1038/nature01406
178 rdf:type schema:CreativeWork
179 sg:pub.10.1038/nchem.2183 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039653945
180 https://doi.org/10.1038/nchem.2183
181 rdf:type schema:CreativeWork
182 sg:pub.10.1038/nchem.2545 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032245652
183 https://doi.org/10.1038/nchem.2545
184 rdf:type schema:CreativeWork
185 sg:pub.10.1038/nnano.2014.246 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016806675
186 https://doi.org/10.1038/nnano.2014.246
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1002/anie.201407729 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027976480
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1002/jcc.20289 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040543339
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1006/jmbi.1996.0157 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017094374
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1006/jmbi.1998.1875 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012732749
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1016/0009-2614(75)80190-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028788082
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1016/j.susc.2016.03.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009138080
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1016/s1074-5521(00)00133-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042717789
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1021/acs.chemrev.5b00298 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024367766
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1021/acs.jpclett.5b00863 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055113806
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1021/ar0000197 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055148121
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1021/ar400079s schema:sameAs https://app.dimensions.ai/details/publication/pub.1055150389
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1021/ar990040b schema:sameAs https://app.dimensions.ai/details/publication/pub.1055152406
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1021/bi9007484 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055209872
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1021/cr900228f schema:sameAs https://app.dimensions.ai/details/publication/pub.1053965454
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1021/ja0032632 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055723564
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1021/ja065864k schema:sameAs https://app.dimensions.ai/details/publication/pub.1029863403
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1021/ja2076857 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018579720
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1021/ja9609821 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055864975
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1021/jacs.5b00931 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055873778
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1021/jp001109w schema:sameAs https://app.dimensions.ai/details/publication/pub.1056042900
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1021/jp110871g schema:sameAs https://app.dimensions.ai/details/publication/pub.1056080657
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1021/jp404788t schema:sameAs https://app.dimensions.ai/details/publication/pub.1056095662
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1021/jp512767j schema:sameAs https://app.dimensions.ai/details/publication/pub.1056104875
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1021/jp9933323 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056132154
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1021/nl0494295 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056216060
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1039/c4fd00106k schema:sameAs https://app.dimensions.ai/details/publication/pub.1026097971
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1063/1.3460132 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012034346
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1073/pnas.48.12.2013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047929716
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1073/pnas.95.22.12759 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035031498
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1093/nar/29.10.2026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017858591
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1126/science.1087481 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062448383
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1126/science.3863253 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062622013
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1146/annurev-biochem-060308-102244 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001467731
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1146/annurev.physchem.54.011002.103746 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042164744
255 rdf:type schema:CreativeWork
256 https://www.grid.ac/institutes/grid.137628.9 schema:alternateName New York University
257 schema:name Department of Chemistry, New York University, New York, NY, USA
258 rdf:type schema:Organization
259 https://www.grid.ac/institutes/grid.170430.1 schema:alternateName University of Central Florida
260 schema:name Departments of Chemistry, Duke University, Durham, NC, USA
261 Nanoscience Technology Center & Department of Physics, University of Central Florida, Orlando, FL, USA
262 rdf:type schema:Organization
263 https://www.grid.ac/institutes/grid.215654.1 schema:alternateName Arizona State University
264 schema:name Biodesign Center for Biosensors and Bioelectronics, Biodesign Institute, Arizona State University, Tempe, AZ, USA
265 School of Molecular Sciences, Arizona State University, Tempe, AZ, USA
266 rdf:type schema:Organization
267 https://www.grid.ac/institutes/grid.26009.3d schema:alternateName Duke University
268 schema:name Department of Biochemistry, Duke University, Durham, NC, USA
269 Department of Physics, Duke University, Durham, NC, USA
270 Departments of Chemistry, Duke University, Durham, NC, USA
271 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...