Environmental stimuli drive a transition from cooperation to competition in synthetic phototrophic communities View Full Text


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Article Info

DATE

2019-10-07

AUTHORS

Cristal Zuñiga, Chien-Ting Li, Geng Yu, Mahmoud M. Al-Bassam, Tingting Li, Liqun Jiang, Livia S. Zaramela, Michael Guarnieri, Michael J. Betenbaugh, Karsten Zengler

ABSTRACT

Phototrophic communities of photosynthetic algae or cyanobacteria and heterotrophic bacteria or fungi are pervasive throughout the environment1. How interactions between members contribute to the resilience and affect the fitness of phototrophic communities is not fully understood2,3. Here, we integrated metatranscriptomics, metabolomics and phenotyping with computational modelling to reveal condition-dependent secretion and cross-feeding of metabolites in a synthetic community. We discovered that interactions between members are highly dynamic and are driven by the availability of organic and inorganic nutrients. Environmental factors, such as ammonia concentration, influenced community stability by shifting members from collaborating to competing. Furthermore, overall fitness was dependent on genotype and streamlined genomes improved growth of the entire community. Our mechanistic framework provides insights into the physiology and metabolic response to environmental and genetic perturbation of these ubiquitous microbial associations. More... »

PAGES

2184-2191

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/s41564-019-0567-6

    DOI

    http://dx.doi.org/10.1038/s41564-019-0567-6

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1121556292

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/31591554


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    RDF/XML is a standard XML format for linked data.

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