Meta-DNA structures View Full Text


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Article Info

DATE

2020-09-07

AUTHORS

Guangbao Yao, Fei Zhang, Fei Wang, Tianhuan Peng, Hao Liu, Erik Poppleton, Petr Šulc, Shuoxing Jiang, Lan Liu, Chen Gong, Xinxin Jing, Xiaoguo Liu, Lihua Wang, Yan Liu, Chunhai Fan, Hao Yan

ABSTRACT

DNA origami has emerged as a highly programmable method to construct customized objects and functional devices in the 10–100 nm scale. Scaling up the size of the DNA origami would enable many potential applications, which include metamaterial construction and surface-based biophysical assays. Here we demonstrate that a six-helix bundle DNA origami nanostructure in the submicrometre scale (meta-DNA) could be used as a magnified analogue of single-stranded DNA, and that two meta-DNAs that contain complementary ‘meta-base pairs’ can form double helices with programmed handedness and helical pitches. By mimicking the molecular behaviours of DNA strands and their assembly strategies, we used meta-DNA building blocks to form diverse and complex structures on the micrometre scale. Using meta-DNA building blocks, we constructed a series of DNA architectures on a submicrometre-to-micrometre scale, which include meta-multi-arm junctions, three-dimensional (3D) polyhedrons, and various 2D/3D lattices. We also demonstrated a hierarchical strand-displacement reaction on meta-DNA to transfer the dynamic features of DNA into the meta-DNA. This meta-DNA self-assembly concept may transform the microscopic world of structural DNA nanotechnology. More... »

PAGES

1067-1075

References to SciGraph publications

  • 2006-05. A DNA Superstructure-based Replicator without Product Inhibition in NATURAL COMPUTING
  • 2017-12-07. Gigadalton-scale shape-programmable DNA assemblies in NATURE
  • 2017-12-07. Biotechnological mass production of DNA origami in NATURE
  • 2010-06-20. Self-assembly of three-dimensional prestressed tensegrity structures from DNA in NATURE NANOTECHNOLOGY
  • 2017-12-07. Fractal assembly of micrometre-scale DNA origami arrays with arbitrary patterns in NATURE
  • 2006-03. Folding DNA to create nanoscale shapes and patterns in NATURE
  • 2012-05-30. Complex shapes self-assembled from single-stranded DNA tiles in NATURE
  • 2014-07-03. Meta-DNA: A DNA-Based Approach to Synthetic Biology in A SYSTEMS THEORETIC APPROACH TO SYSTEMS AND SYNTHETIC BIOLOGY II: ANALYSIS AND DESIGN OF CELLULAR SYSTEMS
  • 1953-04-25. Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid in NATURE
  • 2018-07-16. Complex silica composite nanomaterials templated with DNA origami in NATURE
  • 2011-11-06. Challenges and opportunities for structural DNA nanotechnology in NATURE NANOTECHNOLOGY
  • 2011-07-10. Programmable molecular recognition based on the geometry of DNA nanostructures in NATURE CHEMISTRY
  • 2018-02-12. A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo in NATURE BIOTECHNOLOGY
  • 2011-07-20. Neural network computation with DNA strand displacement cascades in NATURE
  • 2017-05-22. Molecular engineering of chiral colloidal liquid crystals using DNA origami in NATURE MATERIALS
  • 2018-12-18. Information-based autonomous reconfiguration in systems of interacting DNA nanostructures in NATURE COMMUNICATIONS
  • 1983-10. An immobile nucleic acid junction constructed from oligonucleotides in NATURE
  • 2018-11-02. Programming molecular topologies from single-stranded nucleic acids in NATURE COMMUNICATIONS
  • Journal

    TITLE

    Nature Chemistry

    ISSUE

    11

    VOLUME

    12

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/s41557-020-0539-8

    DOI

    http://dx.doi.org/10.1038/s41557-020-0539-8

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1130642930

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/32895523


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