A kinesin mimics DNA View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2022-07-07

AUTHORS

Dhivya Kumar, Jeremy F. Reiter

ABSTRACT

Primary cilia transduce cues, including Hedgehog (Hh) signals, and possess doublet microtubules that interact with kinesin motors. The kinesin KIF7 is important for Hh signalling and binds to GLI transcription factors. Haque et al. reveal that, surprisingly, GLI proteins bind a DNA-like part of KIF7 to promote their accumulation at the ciliary tip. More... »

PAGES

1015-1016

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41556-022-00958-0

DOI

http://dx.doi.org/10.1038/s41556-022-00958-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1149302019

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/35798844


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