Don’t put all your epigenetic eggs in one basket View Full Text


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Article Info

DATE

2022-06-30

AUTHORS

Nicole M. Bush, Craig P. Hunter

ABSTRACT

In Caenorhabditis elegans, RNAi-initiated gene silencing can persist for multiple generations. A study shows that this heritable silencing requires parallel contributions of both a nuclear transcriptional silencing pathway and perinuclear condensate-localized poly(UG)-tailed transcripts to produce abundant germline siRNAs in adult progeny.

PAGES

1016-1018

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41556-022-00948-2

DOI

http://dx.doi.org/10.1038/s41556-022-00948-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1149105270

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/35773433


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