Mesenchymal–epithelial transition in development and reprogramming View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-01

AUTHORS

Duanqing Pei, Xiaodong Shu, Ama Gassama-Diagne, Jean Paul Thiery

ABSTRACT

During organogenesis, epithelial cells can give rise to mesenchymal cells through epithelial-mesenchymal transition. The reverse process, mesenchymal-epithelial transition (MET), can similarly generate epithelial cells. Transitions between epithelial and mesenchymal states are also critical for the induction of pluripotent stem cells from somatic cells. This Review discusses the relatively less characterized process of MET, focusing on the genesis of apicobasal cell polarity and exploring the roles of MET in development and reprogramming. More... »

PAGES

44

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    http://scigraph.springernature.com/pub.10.1038/s41556-018-0195-z

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    http://dx.doi.org/10.1038/s41556-018-0195-z

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1107871621

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30602762


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