Free radical sensors based on inner-cutting graphene field-effect transistors. View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Zhen Wang, Kongyang Yi, Qiuyuan Lin, Lei Yang, Xiaosong Chen, Hui Chen, Yunqi Liu, Dacheng Wei

ABSTRACT

Due to ultra-high reactivity, direct determination of free radicals, especially hydroxyl radical (•OH) with ultra-short lifetime, by field-effect transistor (FET) sensors remains a challenge, which hampers evaluating the role that free radical plays in physiological and pathological processes. Here, we develop a •OH FET sensor with a graphene channel functionalized by metal ion indicators. At the electrolyte/graphene interface, highly reactive •OH cuts the cysteamine to release the metal ions, resulting in surface charge de-doping and a current response. By this inner-cutting strategy, the •OH is selectively detected with a concentration down to 10-9 M. Quantitative metal ion doping enables modulation of the device sensitivity and a quasi-quantitative detection of •OH generated in aqueous solution or from living cells. Owing to its high sensitivity, selectivity, real-time label-free response, capability for quasi-quantitative detection and user-friendly portable feature, it is valuable in biological research, human health, environmental monitoring, etc. More... »

PAGES

1544

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41467-019-09573-4

DOI

http://dx.doi.org/10.1038/s41467-019-09573-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1113184951

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30948705


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0306", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Physical Chemistry (incl. Structural)", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/03", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Chemical Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Fudan University", 
          "id": "https://www.grid.ac/institutes/grid.8547.e", 
          "name": [
            "State Key Laboratory of Molecular Engineering of Polymers, Fudan University, 200433, Shanghai, China.", 
            "Department of Macromolecular Science, Fudan University, 200433, Shanghai, China.", 
            "Institute of Molecular Materials and Devices, Fudan University, 200433, Shanghai, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wang", 
        "givenName": "Zhen", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Fudan University", 
          "id": "https://www.grid.ac/institutes/grid.8547.e", 
          "name": [
            "State Key Laboratory of Molecular Engineering of Polymers, Fudan University, 200433, Shanghai, China.", 
            "Department of Macromolecular Science, Fudan University, 200433, Shanghai, China.", 
            "Institute of Molecular Materials and Devices, Fudan University, 200433, Shanghai, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yi", 
        "givenName": "Kongyang", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Fudan University", 
          "id": "https://www.grid.ac/institutes/grid.8547.e", 
          "name": [
            "Department of Chemistry, Fudan University, 200433, Shanghai, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lin", 
        "givenName": "Qiuyuan", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Fudan University", 
          "id": "https://www.grid.ac/institutes/grid.8547.e", 
          "name": [
            "State Key Laboratory of Molecular Engineering of Polymers, Fudan University, 200433, Shanghai, China.", 
            "Department of Macromolecular Science, Fudan University, 200433, Shanghai, China.", 
            "Institute of Molecular Materials and Devices, Fudan University, 200433, Shanghai, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yang", 
        "givenName": "Lei", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Fudan University", 
          "id": "https://www.grid.ac/institutes/grid.8547.e", 
          "name": [
            "State Key Laboratory of Molecular Engineering of Polymers, Fudan University, 200433, Shanghai, China.", 
            "Department of Macromolecular Science, Fudan University, 200433, Shanghai, China.", 
            "Institute of Molecular Materials and Devices, Fudan University, 200433, Shanghai, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chen", 
        "givenName": "Xiaosong", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Fudan University", 
          "id": "https://www.grid.ac/institutes/grid.8547.e", 
          "name": [
            "Department of Chemistry, Fudan University, 200433, Shanghai, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chen", 
        "givenName": "Hui", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Fudan University", 
          "id": "https://www.grid.ac/institutes/grid.8547.e", 
          "name": [
            "Institute of Molecular Materials and Devices, Fudan University, 200433, Shanghai, China."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Liu", 
        "givenName": "Yunqi", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Fudan University", 
          "id": "https://www.grid.ac/institutes/grid.8547.e", 
          "name": [
            "State Key Laboratory of Molecular Engineering of Polymers, Fudan University, 200433, Shanghai, China. weidc@fudan.edu.cn.", 
            "Department of Macromolecular Science, Fudan University, 200433, Shanghai, China. weidc@fudan.edu.cn.", 
            "Institute of Molecular Materials and Devices, Fudan University, 200433, Shanghai, China. weidc@fudan.edu.cn."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wei", 
        "givenName": "Dacheng", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.talanta.2004.08.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000625966"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nchembio.607", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002205143", 
          "https://doi.org/10.1038/nchembio.607"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/nn402702w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005374348"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/smll.201203152", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005815348"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.freeradbiomed.2003.09.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008000441"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/nl1002608", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008554691"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/nl1002608", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008554691"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja805090z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009283505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja805090z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009283505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0009-9120(96)00137-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009459235"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/nn800593m", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009747736"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0891-5849(99)00049-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010511286"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrm2240", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015577356", 
          "https://doi.org/10.1038/nrm2240"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/acs.nanolett.5b02286", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017656519"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/nl201332c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019199150"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/nl201332c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019199150"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep09332", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019369219", 
          "https://doi.org/10.1038/srep09332"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.98.1.355", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019923223"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/acs.chemrev.5b00608", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020155761"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nchembio.85", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021452802", 
          "https://doi.org/10.1038/nchembio.85"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ac403810g", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022073195"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja108127r", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023094544"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja108127r", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023094544"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/adma.201603610", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026348169"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/nl071792z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027126650"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/nl071792z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027126650"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0039-9140(82)80001-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028433916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c3nr03940d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029557136"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/3-540-30592-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030230879", 
          "https://doi.org/10.1007/3-540-30592-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/3-540-30592-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030230879", 
          "https://doi.org/10.1007/3-540-30592-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12274-014-0658-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030448730", 
          "https://doi.org/10.1007/s12274-014-0658-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0039-9140(03)00149-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034854186"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0039-9140(03)00149-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034854186"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ac102874x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036949279"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ac102874x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036949279"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c3cc42377h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039502078"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmat1967", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043196688", 
          "https://doi.org/10.1038/nmat1967"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1088/0957-4484/20/44/445502", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043520720"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c0cc05821a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043740958"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c5ra05159b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044635796"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep21711", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046498499", 
          "https://doi.org/10.1038/srep21711"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/adma.201102990", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047094107"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/v74-527", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048716520"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/am505275a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049191611"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bios.2015.06.068", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050524201"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/abbi.1996.0452", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050934842"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/adfm.200801838", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050951939"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/adfm.200801838", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050951939"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/abbi.1996.0067", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051383675"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1534735404270612", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051439948"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1534735404270612", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051439948"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/nl901596m", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053672187"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/nl901596m", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053672187"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/cr1001904", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053798683"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/cr1001904", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053798683"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ac3000336", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055002573"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/acsami.6b12047", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055132364"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja00495a010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055737127"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja9041862", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055861638"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja9041862", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055861638"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jz900351w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056136141"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jz900351w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056136141"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/nn4063424", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056225825"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1063/1.3581882", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057978909"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075630074", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/acsami.7b07684", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090958687"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.chempr.2018.03.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103239578"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jhazmat.2018.04.063", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103667033"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-12", 
    "datePublishedReg": "2019-12-01", 
    "description": "Due to ultra-high reactivity, direct determination of free radicals, especially hydroxyl radical (\u2022OH) with ultra-short lifetime, by field-effect transistor (FET) sensors remains a challenge, which hampers evaluating the role that free radical plays in physiological and pathological processes. Here, we develop a \u2022OH FET sensor with a graphene channel functionalized by metal ion indicators. At the electrolyte/graphene interface, highly reactive \u2022OH cuts the cysteamine to release the metal ions, resulting in surface charge de-doping and a current response. By this inner-cutting strategy, the \u2022OH is selectively detected with a concentration down to 10-9 M. Quantitative metal ion doping enables modulation of the device sensitivity and a quasi-quantitative detection of \u2022OH generated in aqueous solution or from living cells. Owing to its high sensitivity, selectivity, real-time label-free response, capability for quasi-quantitative detection and user-friendly portable feature, it is valuable in biological research, human health, environmental monitoring, etc.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/s41467-019-09573-4", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1043282", 
        "issn": [
          "2041-1723"
        ], 
        "name": "Nature Communications", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "10"
      }
    ], 
    "name": "Free radical sensors based on inner-cutting graphene field-effect transistors.", 
    "pagination": "1544", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s41467-019-09573-4"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1113184951"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101528555"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30948705"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s41467-019-09573-4", 
      "https://app.dimensions.ai/details/publication/pub.1113184951"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-16T06:26", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000377_0000000377/records_106844_00000002.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/s41467-019-09573-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41467-019-09573-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41467-019-09573-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41467-019-09573-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41467-019-09573-4'


 

This table displays all metadata directly associated to this object as RDF triples.

280 TRIPLES      21 PREDICATES      82 URIs      20 LITERALS      8 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s41467-019-09573-4 schema:about anzsrc-for:03
2 anzsrc-for:0306
3 schema:author Ned390d8328844e099b3105f5697dce68
4 schema:citation sg:pub.10.1007/3-540-30592-0
5 sg:pub.10.1007/s12274-014-0658-x
6 sg:pub.10.1038/nchembio.607
7 sg:pub.10.1038/nchembio.85
8 sg:pub.10.1038/nmat1967
9 sg:pub.10.1038/nrm2240
10 sg:pub.10.1038/srep09332
11 sg:pub.10.1038/srep21711
12 https://app.dimensions.ai/details/publication/pub.1075630074
13 https://doi.org/10.1002/adfm.200801838
14 https://doi.org/10.1002/adma.201102990
15 https://doi.org/10.1002/adma.201603610
16 https://doi.org/10.1002/smll.201203152
17 https://doi.org/10.1006/abbi.1996.0067
18 https://doi.org/10.1006/abbi.1996.0452
19 https://doi.org/10.1016/0039-9140(82)80001-5
20 https://doi.org/10.1016/j.bios.2015.06.068
21 https://doi.org/10.1016/j.chempr.2018.03.002
22 https://doi.org/10.1016/j.freeradbiomed.2003.09.005
23 https://doi.org/10.1016/j.jhazmat.2018.04.063
24 https://doi.org/10.1016/j.talanta.2004.08.019
25 https://doi.org/10.1016/s0009-9120(96)00137-3
26 https://doi.org/10.1016/s0039-9140(03)00149-8
27 https://doi.org/10.1016/s0891-5849(99)00049-0
28 https://doi.org/10.1021/ac102874x
29 https://doi.org/10.1021/ac3000336
30 https://doi.org/10.1021/ac403810g
31 https://doi.org/10.1021/acs.chemrev.5b00608
32 https://doi.org/10.1021/acs.nanolett.5b02286
33 https://doi.org/10.1021/acsami.6b12047
34 https://doi.org/10.1021/acsami.7b07684
35 https://doi.org/10.1021/am505275a
36 https://doi.org/10.1021/cr1001904
37 https://doi.org/10.1021/ja00495a010
38 https://doi.org/10.1021/ja108127r
39 https://doi.org/10.1021/ja805090z
40 https://doi.org/10.1021/ja9041862
41 https://doi.org/10.1021/jz900351w
42 https://doi.org/10.1021/nl071792z
43 https://doi.org/10.1021/nl1002608
44 https://doi.org/10.1021/nl201332c
45 https://doi.org/10.1021/nl901596m
46 https://doi.org/10.1021/nn402702w
47 https://doi.org/10.1021/nn4063424
48 https://doi.org/10.1021/nn800593m
49 https://doi.org/10.1039/c0cc05821a
50 https://doi.org/10.1039/c3cc42377h
51 https://doi.org/10.1039/c3nr03940d
52 https://doi.org/10.1039/c5ra05159b
53 https://doi.org/10.1063/1.3581882
54 https://doi.org/10.1073/pnas.98.1.355
55 https://doi.org/10.1088/0957-4484/20/44/445502
56 https://doi.org/10.1139/v74-527
57 https://doi.org/10.1177/1534735404270612
58 schema:datePublished 2019-12
59 schema:datePublishedReg 2019-12-01
60 schema:description Due to ultra-high reactivity, direct determination of free radicals, especially hydroxyl radical (•OH) with ultra-short lifetime, by field-effect transistor (FET) sensors remains a challenge, which hampers evaluating the role that free radical plays in physiological and pathological processes. Here, we develop a •OH FET sensor with a graphene channel functionalized by metal ion indicators. At the electrolyte/graphene interface, highly reactive •OH cuts the cysteamine to release the metal ions, resulting in surface charge de-doping and a current response. By this inner-cutting strategy, the •OH is selectively detected with a concentration down to 10<sup>-9</sup> M. Quantitative metal ion doping enables modulation of the device sensitivity and a quasi-quantitative detection of •OH generated in aqueous solution or from living cells. Owing to its high sensitivity, selectivity, real-time label-free response, capability for quasi-quantitative detection and user-friendly portable feature, it is valuable in biological research, human health, environmental monitoring, etc.
61 schema:genre research_article
62 schema:inLanguage en
63 schema:isAccessibleForFree true
64 schema:isPartOf N092f2a61d0f0443a8f5c5094b6d28a3a
65 N2a19c39d5cd2452b972722fd2a097cad
66 sg:journal.1043282
67 schema:name Free radical sensors based on inner-cutting graphene field-effect transistors.
68 schema:pagination 1544
69 schema:productId N022d115ed6fc4c978a20736ecaacd022
70 N46206864905c45b68ba6090929990291
71 Nd3ea71e658874a40b8c0402df657c9f1
72 Nfa9ad95eeedf4a0cae5fbd26fb8607c3
73 schema:sameAs https://app.dimensions.ai/details/publication/pub.1113184951
74 https://doi.org/10.1038/s41467-019-09573-4
75 schema:sdDatePublished 2019-04-16T06:26
76 schema:sdLicense https://scigraph.springernature.com/explorer/license/
77 schema:sdPublisher N8cec428bd355459386c23b931edd724e
78 schema:url http://www.nature.com/articles/s41467-019-09573-4
79 sgo:license sg:explorer/license/
80 sgo:sdDataset articles
81 rdf:type schema:ScholarlyArticle
82 N022d115ed6fc4c978a20736ecaacd022 schema:name doi
83 schema:value 10.1038/s41467-019-09573-4
84 rdf:type schema:PropertyValue
85 N092f2a61d0f0443a8f5c5094b6d28a3a schema:issueNumber 1
86 rdf:type schema:PublicationIssue
87 N0de31e317c354cc59cfcafe6307c6e1e schema:affiliation https://www.grid.ac/institutes/grid.8547.e
88 schema:familyName Yi
89 schema:givenName Kongyang
90 rdf:type schema:Person
91 N122c7510c25f4a18b48b801a55b8555c schema:affiliation https://www.grid.ac/institutes/grid.8547.e
92 schema:familyName Wang
93 schema:givenName Zhen
94 rdf:type schema:Person
95 N1334fdd6a88d4bab852fcf33f627d344 schema:affiliation https://www.grid.ac/institutes/grid.8547.e
96 schema:familyName Liu
97 schema:givenName Yunqi
98 rdf:type schema:Person
99 N18d900ea85da4b519dd0eeb13180beb6 rdf:first N5517419445e14520b42968df14588834
100 rdf:rest Nba38ab54c5734fc7a9d1269f094860ea
101 N2a19c39d5cd2452b972722fd2a097cad schema:volumeNumber 10
102 rdf:type schema:PublicationVolume
103 N2f51362e5c51441b95e02a422e00dd6b rdf:first N4b244e8f85874db3a2bd3c7f748c7e8a
104 rdf:rest N18d900ea85da4b519dd0eeb13180beb6
105 N46206864905c45b68ba6090929990291 schema:name pubmed_id
106 schema:value 30948705
107 rdf:type schema:PropertyValue
108 N4b244e8f85874db3a2bd3c7f748c7e8a schema:affiliation https://www.grid.ac/institutes/grid.8547.e
109 schema:familyName Yang
110 schema:givenName Lei
111 rdf:type schema:Person
112 N543bea7cfdff43acbd7d48479a095301 rdf:first N586b846332754a89bff7f951111e32b9
113 rdf:rest rdf:nil
114 N5517419445e14520b42968df14588834 schema:affiliation https://www.grid.ac/institutes/grid.8547.e
115 schema:familyName Chen
116 schema:givenName Xiaosong
117 rdf:type schema:Person
118 N586b846332754a89bff7f951111e32b9 schema:affiliation https://www.grid.ac/institutes/grid.8547.e
119 schema:familyName Wei
120 schema:givenName Dacheng
121 rdf:type schema:Person
122 N850d204169984ad1b02d18eabafa100a rdf:first N9d40c8d262b140f38dcf0a62b9d403e4
123 rdf:rest N2f51362e5c51441b95e02a422e00dd6b
124 N8cec428bd355459386c23b931edd724e schema:name Springer Nature - SN SciGraph project
125 rdf:type schema:Organization
126 N9d40c8d262b140f38dcf0a62b9d403e4 schema:affiliation https://www.grid.ac/institutes/grid.8547.e
127 schema:familyName Lin
128 schema:givenName Qiuyuan
129 rdf:type schema:Person
130 Nb7eac846d4614cdc9ac456b99da02901 schema:affiliation https://www.grid.ac/institutes/grid.8547.e
131 schema:familyName Chen
132 schema:givenName Hui
133 rdf:type schema:Person
134 Nba38ab54c5734fc7a9d1269f094860ea rdf:first Nb7eac846d4614cdc9ac456b99da02901
135 rdf:rest Nbe24a0251a6a4f248405913844ee1c2b
136 Nbe24a0251a6a4f248405913844ee1c2b rdf:first N1334fdd6a88d4bab852fcf33f627d344
137 rdf:rest N543bea7cfdff43acbd7d48479a095301
138 Nd3ea71e658874a40b8c0402df657c9f1 schema:name dimensions_id
139 schema:value pub.1113184951
140 rdf:type schema:PropertyValue
141 Neb7c69af002d4285af78bb0c8209792a rdf:first N0de31e317c354cc59cfcafe6307c6e1e
142 rdf:rest N850d204169984ad1b02d18eabafa100a
143 Ned390d8328844e099b3105f5697dce68 rdf:first N122c7510c25f4a18b48b801a55b8555c
144 rdf:rest Neb7c69af002d4285af78bb0c8209792a
145 Nfa9ad95eeedf4a0cae5fbd26fb8607c3 schema:name nlm_unique_id
146 schema:value 101528555
147 rdf:type schema:PropertyValue
148 anzsrc-for:03 schema:inDefinedTermSet anzsrc-for:
149 schema:name Chemical Sciences
150 rdf:type schema:DefinedTerm
151 anzsrc-for:0306 schema:inDefinedTermSet anzsrc-for:
152 schema:name Physical Chemistry (incl. Structural)
153 rdf:type schema:DefinedTerm
154 sg:journal.1043282 schema:issn 2041-1723
155 schema:name Nature Communications
156 rdf:type schema:Periodical
157 sg:pub.10.1007/3-540-30592-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030230879
158 https://doi.org/10.1007/3-540-30592-0
159 rdf:type schema:CreativeWork
160 sg:pub.10.1007/s12274-014-0658-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1030448730
161 https://doi.org/10.1007/s12274-014-0658-x
162 rdf:type schema:CreativeWork
163 sg:pub.10.1038/nchembio.607 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002205143
164 https://doi.org/10.1038/nchembio.607
165 rdf:type schema:CreativeWork
166 sg:pub.10.1038/nchembio.85 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021452802
167 https://doi.org/10.1038/nchembio.85
168 rdf:type schema:CreativeWork
169 sg:pub.10.1038/nmat1967 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043196688
170 https://doi.org/10.1038/nmat1967
171 rdf:type schema:CreativeWork
172 sg:pub.10.1038/nrm2240 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015577356
173 https://doi.org/10.1038/nrm2240
174 rdf:type schema:CreativeWork
175 sg:pub.10.1038/srep09332 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019369219
176 https://doi.org/10.1038/srep09332
177 rdf:type schema:CreativeWork
178 sg:pub.10.1038/srep21711 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046498499
179 https://doi.org/10.1038/srep21711
180 rdf:type schema:CreativeWork
181 https://app.dimensions.ai/details/publication/pub.1075630074 schema:CreativeWork
182 https://doi.org/10.1002/adfm.200801838 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050951939
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1002/adma.201102990 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047094107
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1002/adma.201603610 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026348169
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1002/smll.201203152 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005815348
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1006/abbi.1996.0067 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051383675
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1006/abbi.1996.0452 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050934842
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1016/0039-9140(82)80001-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028433916
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1016/j.bios.2015.06.068 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050524201
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1016/j.chempr.2018.03.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103239578
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1016/j.freeradbiomed.2003.09.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008000441
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1016/j.jhazmat.2018.04.063 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103667033
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1016/j.talanta.2004.08.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000625966
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1016/s0009-9120(96)00137-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009459235
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1016/s0039-9140(03)00149-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034854186
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1016/s0891-5849(99)00049-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010511286
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1021/ac102874x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036949279
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1021/ac3000336 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055002573
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1021/ac403810g schema:sameAs https://app.dimensions.ai/details/publication/pub.1022073195
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1021/acs.chemrev.5b00608 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020155761
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1021/acs.nanolett.5b02286 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017656519
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1021/acsami.6b12047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055132364
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1021/acsami.7b07684 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090958687
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1021/am505275a schema:sameAs https://app.dimensions.ai/details/publication/pub.1049191611
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1021/cr1001904 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053798683
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1021/ja00495a010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055737127
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1021/ja108127r schema:sameAs https://app.dimensions.ai/details/publication/pub.1023094544
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1021/ja805090z schema:sameAs https://app.dimensions.ai/details/publication/pub.1009283505
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1021/ja9041862 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055861638
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1021/jz900351w schema:sameAs https://app.dimensions.ai/details/publication/pub.1056136141
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1021/nl071792z schema:sameAs https://app.dimensions.ai/details/publication/pub.1027126650
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1021/nl1002608 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008554691
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1021/nl201332c schema:sameAs https://app.dimensions.ai/details/publication/pub.1019199150
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1021/nl901596m schema:sameAs https://app.dimensions.ai/details/publication/pub.1053672187
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1021/nn402702w schema:sameAs https://app.dimensions.ai/details/publication/pub.1005374348
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1021/nn4063424 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056225825
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1021/nn800593m schema:sameAs https://app.dimensions.ai/details/publication/pub.1009747736
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1039/c0cc05821a schema:sameAs https://app.dimensions.ai/details/publication/pub.1043740958
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1039/c3cc42377h schema:sameAs https://app.dimensions.ai/details/publication/pub.1039502078
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1039/c3nr03940d schema:sameAs https://app.dimensions.ai/details/publication/pub.1029557136
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1039/c5ra05159b schema:sameAs https://app.dimensions.ai/details/publication/pub.1044635796
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1063/1.3581882 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057978909
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1073/pnas.98.1.355 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019923223
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1088/0957-4484/20/44/445502 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043520720
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1139/v74-527 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048716520
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1177/1534735404270612 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051439948
271 rdf:type schema:CreativeWork
272 https://www.grid.ac/institutes/grid.8547.e schema:alternateName Fudan University
273 schema:name Department of Chemistry, Fudan University, 200433, Shanghai, China.
274 Department of Macromolecular Science, Fudan University, 200433, Shanghai, China.
275 Department of Macromolecular Science, Fudan University, 200433, Shanghai, China. weidc@fudan.edu.cn.
276 Institute of Molecular Materials and Devices, Fudan University, 200433, Shanghai, China.
277 Institute of Molecular Materials and Devices, Fudan University, 200433, Shanghai, China. weidc@fudan.edu.cn.
278 State Key Laboratory of Molecular Engineering of Polymers, Fudan University, 200433, Shanghai, China.
279 State Key Laboratory of Molecular Engineering of Polymers, Fudan University, 200433, Shanghai, China. weidc@fudan.edu.cn.
280 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...