Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02 View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Christos Tziotzios, Christos Petridis, Nick Dand, Chrysanthi Ainali, Jake R. Saklatvala, Venu Pullabhatla, Alexandros Onoufriadis, Rashida Pramanik, David Baudry, Sang Hyuck Lee, Kristie Wood, Lu Liu, Seth Seegobin, Gregory A. Michelotti, Su M. Lwin, Evangelos A. A. Christou, Charles J. Curtis, Emanuele de Rinaldis, Alka Saxena, Susan Holmes, Matthew Harries, Ioulios Palamaras, Fiona Cunningham, Gregory Parkins, Manjit Kaur, Paul Farrant, Andrew McDonagh, Andrew Messenger, Jennifer Jones, Victoria Jolliffe, Iaisha Ali, Michael Ardern-Jones, Charles Mitchell, Nigel Burrows, Ravinder Atkar, Cedric Banfield, Anton Alexandroff, Caroline Champagne, Hywel L. Cooper, Sergio Vañó-Galván, Ana Maria Molina-Ruiz, Nerea Ormaechea Perez, Girish K. Patel, Abby Macbeth, Melanie Page, Alyson Bryden, Megan Mowbray, Shyamal Wahie, Keith Armstrong, Nicola Cooke, Mark Goodfield, Irene Man, David de Berker, Giles Dunnill, Anita Takwale, Archana Rao, Tee-Wei Siah, Rodney Sinclair, Martin S. Wade, Ncoza C. Dlova, Jane Setterfield, Fiona Lewis, Kapil Bhargava, Niall Kirkpatrick, Xavier Estivill, Catherine M. Stefanato, Carsten Flohr, Timothy Spector, Fiona M. Watt, Catherine H. Smith, Jonathan N. Barker, David A. Fenton, Michael A. Simpson, John A. McGrath

ABSTRACT

Frontal fibrosing alopecia (FFA) is a recently described inflammatory and scarring type of hair loss affecting almost exclusively women. Despite a dramatic recent increase in incidence the aetiopathogenesis of FFA remains unknown. We undertake genome-wide association studies in females from a UK cohort, comprising 844 cases and 3,760 controls, a Spanish cohort of 172 cases and 385 controls, and perform statistical meta-analysis. We observe genome-wide significant association with FFA at four genomic loci: 2p22.2, 6p21.1, 8q24.22 and 15q2.1. Within the 6p21.1 locus, fine-mapping indicates that the association is driven by the HLA-B*07:02 allele. At 2p22.1, we implicate a putative causal missense variant in CYP1B1, encoding the homonymous xenobiotic- and hormone-processing enzyme. Transcriptomic analysis of affected scalp tissue highlights overrepresentation of transcripts encoding components of innate and adaptive immune response pathways. These findings provide insight into disease pathogenesis and characterise FFA as a genetically predisposed immuno-inflammatory disorder driven by HLA-B*07:02. More... »

PAGES

1150

Journal

TITLE

Nature Communications

ISSUE

1

VOLUME

10

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41467-019-09117-w

DOI

http://dx.doi.org/10.1038/s41467-019-09117-w

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112641448

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30850646


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adaptive Immunity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Alopecia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Case-Control Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cohort Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cytochrome P-450 CYP1B1", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Loci", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Predisposition to Disease", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genome, Human", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genome-Wide Association Study", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HLA-B7 Antigen", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunity, Innate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polymorphism, Single Nucleotide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transcriptome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "St. John\u2019s Institute of Dermatology, King\u2019s College London, London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tziotzios", 
        "givenName": "Christos", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "Department of Medical and Molecular Genetics, King\u2019s College London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Petridis", 
        "givenName": "Christos", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "Department of Medical and Molecular Genetics, King\u2019s College London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dand", 
        "givenName": "Nick", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "St. John\u2019s Institute of Dermatology, King\u2019s College London, London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ainali", 
        "givenName": "Chrysanthi", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "Department of Medical and Molecular Genetics, King\u2019s College London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Saklatvala", 
        "givenName": "Jake R.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Guy's and St Thomas' NHS Foundation Trust", 
          "id": "https://www.grid.ac/institutes/grid.420545.2", 
          "name": [
            "UK NIHR GSTFT/KCL Comprehensive Biomedical Research Centre, Guy\u2019s & St. Thomas\u2019 NHS Foundation Trust, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pullabhatla", 
        "givenName": "Venu", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "St. John\u2019s Institute of Dermatology, King\u2019s College London, London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Onoufriadis", 
        "givenName": "Alexandros", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Guy's and St Thomas' NHS Foundation Trust", 
          "id": "https://www.grid.ac/institutes/grid.420545.2", 
          "name": [
            "UK NIHR GSTFT/KCL Comprehensive Biomedical Research Centre, Guy\u2019s & St. Thomas\u2019 NHS Foundation Trust, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pramanik", 
        "givenName": "Rashida", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "St. John\u2019s Institute of Dermatology, King\u2019s College London, London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Baudry", 
        "givenName": "David", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "NIHR Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust (SLaM) & Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King\u2019s College London, Denmark Hill Campus, SE5 8EF, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lee", 
        "givenName": "Sang Hyuck", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Guy's and St Thomas' NHS Foundation Trust", 
          "id": "https://www.grid.ac/institutes/grid.420545.2", 
          "name": [
            "UK NIHR GSTFT/KCL Comprehensive Biomedical Research Centre, Guy\u2019s & St. Thomas\u2019 NHS Foundation Trust, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wood", 
        "givenName": "Kristie", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "St Thomas' Hospital", 
          "id": "https://www.grid.ac/institutes/grid.425213.3", 
          "name": [
            "National Diagnostic EB Laboratory, St. Thomas Hospital, SE1 7EH, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Liu", 
        "givenName": "Lu", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "St. John\u2019s Institute of Dermatology, King\u2019s College London, London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Seegobin", 
        "givenName": "Seth", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Metabolon (United States)", 
          "id": "https://www.grid.ac/institutes/grid.429438.0", 
          "name": [
            "Metabolon, Inc., 27560, Morrisville, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Michelotti", 
        "givenName": "Gregory A.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "St. John\u2019s Institute of Dermatology, King\u2019s College London, London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lwin", 
        "givenName": "Su M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "St. John\u2019s Institute of Dermatology, King\u2019s College London, London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Christou", 
        "givenName": "Evangelos A. A.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Guy's and St Thomas' NHS Foundation Trust", 
          "id": "https://www.grid.ac/institutes/grid.420545.2", 
          "name": [
            "UK NIHR GSTFT/KCL Comprehensive Biomedical Research Centre, Guy\u2019s & St. Thomas\u2019 NHS Foundation Trust, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Curtis", 
        "givenName": "Charles J.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Guy's and St Thomas' NHS Foundation Trust", 
          "id": "https://www.grid.ac/institutes/grid.420545.2", 
          "name": [
            "UK NIHR GSTFT/KCL Comprehensive Biomedical Research Centre, Guy\u2019s & St. Thomas\u2019 NHS Foundation Trust, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "de Rinaldis", 
        "givenName": "Emanuele", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Guy's and St Thomas' NHS Foundation Trust", 
          "id": "https://www.grid.ac/institutes/grid.420545.2", 
          "name": [
            "UK NIHR GSTFT/KCL Comprehensive Biomedical Research Centre, Guy\u2019s & St. Thomas\u2019 NHS Foundation Trust, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Saxena", 
        "givenName": "Alka", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Alan Lyell Centre for Dermatology, Queen Elizabeth University Hospital, G51 4TF, Glasgow, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Holmes", 
        "givenName": "Susan", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Salford Royal NHS Foundation Trust", 
          "id": "https://www.grid.ac/institutes/grid.412346.6", 
          "name": [
            "The Dermatology Centre, The University of Manchester, Salford Royal NHS Foundation Trust, M6 8HD, Salford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Harries", 
        "givenName": "Matthew", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Barnet Hospital", 
          "id": "https://www.grid.ac/institutes/grid.414254.2", 
          "name": [
            "Department of Dermatology, Barnet General Hospital, Royal Free Foundation Trust, EN5 3DJ, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Palamaras", 
        "givenName": "Ioulios", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Alan Lyell Centre for Dermatology, Queen Elizabeth University Hospital, G51 4TF, Glasgow, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cunningham", 
        "givenName": "Fiona", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Alan Lyell Centre for Dermatology, Queen Elizabeth University Hospital, G51 4TF, Glasgow, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Parkins", 
        "givenName": "Gregory", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Solihull Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416109.b", 
          "name": [
            "Department of Dermatology, Solihull Hospital, B91 2JL, Solihull, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kaur", 
        "givenName": "Manjit", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Brighton and Sussex University Hospitals NHS Trust", 
          "id": "https://www.grid.ac/institutes/grid.410725.5", 
          "name": [
            "Department of Dermatology, Brighton and Sussex University Hospitals NHS Trust, BN2 3EW, Brighton, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Farrant", 
        "givenName": "Paul", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Royal Hallamshire Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416126.6", 
          "name": [
            "Department of Dermatology, Royal Hallamshire Hospital, S10 2JF, Sheffield, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "McDonagh", 
        "givenName": "Andrew", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Royal Hallamshire Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416126.6", 
          "name": [
            "Department of Dermatology, Royal Hallamshire Hospital, S10 2JF, Sheffield, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Messenger", 
        "givenName": "Andrew", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Royal Free Hospital", 
          "id": "https://www.grid.ac/institutes/grid.426108.9", 
          "name": [
            "Department of Dermatology, Royal Free Hospital, NW3 2QG, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jones", 
        "givenName": "Jennifer", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Royal London Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416041.6", 
          "name": [
            "Department of Dermatology, Royal London Hospital, Barts Health NHS Trust, E1 1BB, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jolliffe", 
        "givenName": "Victoria", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Imperial College Healthcare NHS Trust", 
          "id": "https://www.grid.ac/institutes/grid.417895.6", 
          "name": [
            "Department of Dermatology, Imperial College Healthcare NHS Trust, W12 0HS, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ali", 
        "givenName": "Iaisha", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospital Southampton NHS Foundation Trust", 
          "id": "https://www.grid.ac/institutes/grid.430506.4", 
          "name": [
            "Department of Dermatology, University Hospitals Southampton NHS Foundation Trust, SO16 6YD, Southampton, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ardern-Jones", 
        "givenName": "Michael", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Portsmouth Hospitals NHS Trust", 
          "id": "https://www.grid.ac/institutes/grid.418709.3", 
          "name": [
            "Department of Dermatology, Portsmouth Hospitals NHS Trust, PO6 3LY, Portsmouth, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mitchell", 
        "givenName": "Charles", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Addenbrooke's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.120073.7", 
          "name": [
            "Department of Dermatology, Addenbrooke\u2019s Hospital, Cambridge University Hospitals NHS Foundation Trust, CB2 0QQ, Cambridge, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Burrows", 
        "givenName": "Nigel", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Addenbrooke's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.120073.7", 
          "name": [
            "Department of Dermatology, Addenbrooke\u2019s Hospital, Cambridge University Hospitals NHS Foundation Trust, CB2 0QQ, Cambridge, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Atkar", 
        "givenName": "Ravinder", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Peterborough City Hospital", 
          "id": "https://www.grid.ac/institutes/grid.417250.5", 
          "name": [
            "Department of Dermatology, Peterborough City Hospital, PE3 9GZ, Peterborough, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Banfield", 
        "givenName": "Cedric", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Leicester Royal Infirmary", 
          "id": "https://www.grid.ac/institutes/grid.419248.2", 
          "name": [
            "Department of Dermatology, University Hospitals of Leicester, Leicester Royal Infirmary, LE3 9QP, Leicester, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Alexandroff", 
        "givenName": "Anton", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Churchill Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415719.f", 
          "name": [
            "Department of Dermatology, The Churchill Hospital, OX3 7LE, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Champagne", 
        "givenName": "Caroline", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Portsmouth Hospitals NHS Trust", 
          "id": "https://www.grid.ac/institutes/grid.418709.3", 
          "name": [
            "Department of Dermatology, Portsmouth Hospitals NHS Trust, PO6 3LY, Portsmouth, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cooper", 
        "givenName": "Hywel L.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario Ram\u00f3n y Cajal", 
          "id": "https://www.grid.ac/institutes/grid.411347.4", 
          "name": [
            "Trichology Unit, Dermatology Department, Ramon Y Cajal Hospital, University of Alcala, IRYCIS, 28034, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Va\u00f1\u00f3-Galv\u00e1n", 
        "givenName": "Sergio", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz", 
          "id": "https://www.grid.ac/institutes/grid.419651.e", 
          "name": [
            "Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz, 28040, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Molina-Ruiz", 
        "givenName": "Ana Maria", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Donostia Unibertsitate Ospitalea", 
          "id": "https://www.grid.ac/institutes/grid.414651.3", 
          "name": [
            "Department of Dermatology, Hospital Donostia, 20014, San Sebastian, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Perez", 
        "givenName": "Nerea Ormaechea", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hywel Dda University Health Board", 
          "id": "https://www.grid.ac/institutes/grid.428852.1", 
          "name": [
            "Hywel Dda University Health Board, SA31 3BB, Cardiff, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Patel", 
        "givenName": "Girish K.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Norfolk and Norwich University Hospitals NHS Foundation Trust", 
          "id": "https://www.grid.ac/institutes/grid.240367.4", 
          "name": [
            "Department of Dermatology, Norfolk & Norwich University Hospitals NHS Foundation Trust, NR4 7UY, Norwich, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Macbeth", 
        "givenName": "Abby", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Norfolk and Norwich University Hospitals NHS Foundation Trust", 
          "id": "https://www.grid.ac/institutes/grid.240367.4", 
          "name": [
            "Department of Dermatology, Norfolk & Norwich University Hospitals NHS Foundation Trust, NR4 7UY, Norwich, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Page", 
        "givenName": "Melanie", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ninewells Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416266.1", 
          "name": [
            "Department of Dermatology, Ninewells Hospital, DD1 9SY, Dundee, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bryden", 
        "givenName": "Alyson", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Queen Margaret Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415547.6", 
          "name": [
            "Department of Dermatology, Queen Margaret Hospital, KY12 0SU, Dunfermline, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mowbray", 
        "givenName": "Megan", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "County Durham and Darlington NHS Foundation Trust", 
          "id": "https://www.grid.ac/institutes/grid.412907.9", 
          "name": [
            "Department of Dermatology, County Durham and Darlington NHS Foundation Trust, DL3 6HX, Darlington, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wahie", 
        "givenName": "Shyamal", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Royal Victoria Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416232.0", 
          "name": [
            "Department of Dermatology, Royal Victoria Hospital, BT12 6BA, Belfast, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Armstrong", 
        "givenName": "Keith", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Northern Health and Social Care Trust", 
          "id": "https://www.grid.ac/institutes/grid.413824.8", 
          "name": [
            "Department of Dermatology, Whiteabbey Hospital, Northern Health & Social Care Trust, BT37 9RH, Co Antrim, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cooke", 
        "givenName": "Nicola", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chapel Allerton Hospital", 
          "id": "https://www.grid.ac/institutes/grid.413818.7", 
          "name": [
            "Department of Dermatology, Chapel Allerton Hospital, Leeds teaching Hospitals NHS Trust, LS7 4SA, Leeds, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Goodfield", 
        "givenName": "Mark", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Surrey and Sussex Healthcare NHS Trust", 
          "id": "https://www.grid.ac/institutes/grid.439641.d", 
          "name": [
            "Department of Dermatology, Surrey and Sussex Healthcare NHS Trust, RH1 5RH, Surrey, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Man", 
        "givenName": "Irene", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospitals Bristol NHS Foundation Trust", 
          "id": "https://www.grid.ac/institutes/grid.410421.2", 
          "name": [
            "Department of Dermatology, University Hospitals Bristol NHS Foundation Trust, BS2 8HW, Bristol, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "de Berker", 
        "givenName": "David", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospitals Bristol NHS Foundation Trust", 
          "id": "https://www.grid.ac/institutes/grid.410421.2", 
          "name": [
            "Department of Dermatology, University Hospitals Bristol NHS Foundation Trust, BS2 8HW, Bristol, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dunnill", 
        "givenName": "Giles", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Gloucestershire Hospitals NHS Foundation Trust", 
          "id": "https://www.grid.ac/institutes/grid.434530.5", 
          "name": [
            "Department of Dermatology, Gloucestershire Hospitals NHS Foundation Trust, GL1 3NN, Gloucester, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Takwale", 
        "givenName": "Anita", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Dermatology, Kingston Hospital NHS Foundation Trust, KT2 7QB, Kingston-upon-Thames, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rao", 
        "givenName": "Archana", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Royal Victoria Infirmary", 
          "id": "https://www.grid.ac/institutes/grid.419334.8", 
          "name": [
            "Department of Dermatology, Royal Victoria Infirmary, NE1 4LP, Newcastle upon Tyne, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Siah", 
        "givenName": "Tee-Wei", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Melbourne", 
          "id": "https://www.grid.ac/institutes/grid.1008.9", 
          "name": [
            "Department of Dermatology, University of Melbourne, VIC 3010, Melbourne, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sinclair", 
        "givenName": "Rodney", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The London Skin and Hair Clinic, WC1V 7DN, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wade", 
        "givenName": "Martin S.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of KwaZulu-Natal", 
          "id": "https://www.grid.ac/institutes/grid.16463.36", 
          "name": [
            "Department of Dermatology, School of Clinical Medicine, Nelson R Mandela School of Medicine, 4001, Durban, South Africa"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dlova", 
        "givenName": "Ncoza C.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "St. John\u2019s Institute of Dermatology, King\u2019s College London, London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Setterfield", 
        "givenName": "Jane", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "St. John\u2019s Institute of Dermatology, King\u2019s College London, London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lewis", 
        "givenName": "Fiona", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "St. John\u2019s Institute of Dermatology, King\u2019s College London, London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bhargava", 
        "givenName": "Kapil", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chelsea and Westminster Hospital", 
          "id": "https://www.grid.ac/institutes/grid.439369.2", 
          "name": [
            "Craniofacial Surgery Unit, Chelsea & Westminster Hospital, SW10 9NH, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kirkpatrick", 
        "givenName": "Niall", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Genetics Unit, Dexeus Women\u2019s Health, 08028, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Estivill", 
        "givenName": "Xavier", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "Department of Dermatopathology, St. John\u2019s Institute of Dermatology, St. Thomas\u2019 Hospital, SE1 7EH, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stefanato", 
        "givenName": "Catherine M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "St. John\u2019s Institute of Dermatology, King\u2019s College London, London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Flohr", 
        "givenName": "Carsten", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "The Department of Twin Research & Genetic Epidemiology, King\u2019s College London, SE1 7EH, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Spector", 
        "givenName": "Timothy", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "Centre for Stem Cells and Regenerative Medicine, King\u2019s College London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Watt", 
        "givenName": "Fiona M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "St. John\u2019s Institute of Dermatology, King\u2019s College London, London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Smith", 
        "givenName": "Catherine H.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "St. John\u2019s Institute of Dermatology, King\u2019s College London, London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Barker", 
        "givenName": "Jonathan N.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "St. John\u2019s Institute of Dermatology, King\u2019s College London, London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fenton", 
        "givenName": "David A.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "Department of Medical and Molecular Genetics, King\u2019s College London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Simpson", 
        "givenName": "Michael A.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "King's College London", 
          "id": "https://www.grid.ac/institutes/grid.13097.3c", 
          "name": [
            "St. John\u2019s Institute of Dermatology, King\u2019s College London, London, Guy\u2019s Hospital, SE1 9RT, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "McGrath", 
        "givenName": "John A.", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.jaad.2014.05.064", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000129319"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2133.2012.11101.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000537120"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkg509", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002198958"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1124/mol.104.006056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004869238"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1046/j.1087-0024.2003.00807.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006039426", 
          "https://doi.org/10.1046/j.1087-0024.2003.00807.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1087-0024.2003.00807.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006039426"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archderm.1994.01690060100013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006806844"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/meta.2001.25592", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006849397"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.canlet.2014.04.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009126309"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ajhg.2010.11.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009497006"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/exd.13071", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011421154"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gepi.20359", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011882893"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/jocd.12125", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012505359"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/bts090", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014257712"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaad.2009.09.020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014259029"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/bjd.14535", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015814759"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2133.2010.09664.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016173005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2133.2010.09664.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016173005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.2435", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016174016", 
          "https://doi.org/10.1038/ng.2435"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2003-05-1374", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017571842"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/519795", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019061180"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pgen.1004383", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020333172"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1074-7613(00)80180-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020801834"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/btp616", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023247882"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0064683", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023672325"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaad.2015.01.057", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025280694"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/gb-2010-11-12-144", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025477933", 
          "https://doi.org/10.1186/gb-2010-11-12-144"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pharmthera.2012.12.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026929795"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4103/0378-6323.152284", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030253368"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.01750-06", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031565298"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.2653", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032444369", 
          "https://doi.org/10.1038/ng.2653"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaad.2013.12.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033345938"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.humimm.2013.07.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036111361"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0506580102", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037705714"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0506580102", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037705714"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.3211", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044444076", 
          "https://doi.org/10.1038/ng.3211"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.2982", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044995197", 
          "https://doi.org/10.1038/ng.2982"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00210-003-0819-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045914344", 
          "https://doi.org/10.1007/s00210-003-0819-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/btq340", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047276303"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2133.2008.08818.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047542704"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/path.4233", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048276048"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1758-2946-2-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050476991", 
          "https://doi.org/10.1186/1758-2946-2-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/gb-2010-11-3-r25", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050509557", 
          "https://doi.org/10.1186/gb-2010-11-3-r25"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.2892", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050728268", 
          "https://doi.org/10.1038/ng.2892"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archderm.130.6.770", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054099330"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/aid.2013.0197", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059226710"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/en.2003-0192", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064246060"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/1389200216666150206130058", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069176422"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079485310", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/btw624", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083732273"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/btw624", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083732273"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pharmthera.2017.03.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084101568"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep44005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084131907", 
          "https://doi.org/10.1038/srep44005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejmech.2017.04.042", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084911469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaad.2017.08.062", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099650298"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gky310", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103369702"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jid.2018.05.027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1105857642"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/dth.12656", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1107293677"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-12", 
    "datePublishedReg": "2019-12-01", 
    "description": "Frontal fibrosing alopecia (FFA) is a recently described inflammatory and scarring type of hair loss affecting almost exclusively women. Despite a dramatic recent increase in incidence the aetiopathogenesis of FFA remains unknown. We undertake genome-wide association studies in females from a UK cohort, comprising 844 cases and 3,760 controls, a Spanish cohort of 172 cases and 385 controls, and perform statistical meta-analysis. We observe genome-wide significant association with FFA at four genomic loci: 2p22.2, 6p21.1, 8q24.22 and 15q2.1. Within the 6p21.1 locus, fine-mapping indicates that the association is driven by the HLA-B*07:02 allele. At 2p22.1, we implicate a putative causal missense variant in CYP1B1, encoding the homonymous xenobiotic- and hormone-processing enzyme. Transcriptomic analysis of affected scalp tissue highlights overrepresentation of transcripts encoding components of innate and adaptive immune response pathways. These findings provide insight into disease pathogenesis and characterise FFA as a genetically predisposed immuno-inflammatory disorder driven by HLA-B*07:02.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/s41467-019-09117-w", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1043282", 
        "issn": [
          "2041-1723"
        ], 
        "name": "Nature Communications", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "10"
      }
    ], 
    "name": "Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02", 
    "pagination": "1150", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "485852d12a595384ea983422107dbad520bac3acaa22e9ecdb6d013aac08b9dc"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30850646"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101528555"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s41467-019-09117-w"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1112641448"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s41467-019-09117-w", 
      "https://app.dimensions.ai/details/publication/pub.1112641448"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:59", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000371_0000000371/records_130823_00000006.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/s41467-019-09117-w"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41467-019-09117-w'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41467-019-09117-w'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41467-019-09117-w'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41467-019-09117-w'


 

This table displays all metadata directly associated to this object as RDF triples.

866 TRIPLES      21 PREDICATES      100 URIs      37 LITERALS      25 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s41467-019-09117-w schema:about N04c8f338846842a98a90ea44d146417d
2 N0657e005010548719e0a00db1b47bb6b
3 N14f36e18dad242ad9f10639257fbdf5c
4 N18edf8d194604e2b83bb93e10154ad74
5 N29353386656145699d9d4e581c9cb42c
6 N49ba300a022644dfadb0aa40d356a066
7 N523b245faed64324883e57d5eba37772
8 N5a50fb7a65924b5cbb78d6a0828f553b
9 N5c6006f0f24045229a2f91312264099c
10 N6033121778a5483a87b00f95c764751e
11 N76cf571511bc4a018f04464424bde7d5
12 N84f8d095c336432eb8aab9fd12d9d56a
13 N8c64a06d9b6c49d9ac04c26c3271082a
14 N906cee532ab1462f9efae45578f2c420
15 Na64bf23f4b954c52b565fe0c834254cb
16 Nd8a319332f0740aa9d8127d0aa6eb8ab
17 anzsrc-for:06
18 anzsrc-for:0604
19 schema:author Ncb951f3d04f64c25b7974bb1076a6887
20 schema:citation sg:pub.10.1007/s00210-003-0819-z
21 sg:pub.10.1038/ng.2435
22 sg:pub.10.1038/ng.2653
23 sg:pub.10.1038/ng.2892
24 sg:pub.10.1038/ng.2982
25 sg:pub.10.1038/ng.3211
26 sg:pub.10.1038/srep44005
27 sg:pub.10.1046/j.1087-0024.2003.00807.x
28 sg:pub.10.1186/1758-2946-2-9
29 sg:pub.10.1186/gb-2010-11-12-144
30 sg:pub.10.1186/gb-2010-11-3-r25
31 https://app.dimensions.ai/details/publication/pub.1079485310
32 https://doi.org/10.1001/archderm.130.6.770
33 https://doi.org/10.1001/archderm.1994.01690060100013
34 https://doi.org/10.1002/gepi.20359
35 https://doi.org/10.1002/path.4233
36 https://doi.org/10.1016/j.ajhg.2010.11.011
37 https://doi.org/10.1016/j.canlet.2014.04.018
38 https://doi.org/10.1016/j.ejmech.2017.04.042
39 https://doi.org/10.1016/j.humimm.2013.07.014
40 https://doi.org/10.1016/j.jaad.2009.09.020
41 https://doi.org/10.1016/j.jaad.2013.12.003
42 https://doi.org/10.1016/j.jaad.2014.05.064
43 https://doi.org/10.1016/j.jaad.2015.01.057
44 https://doi.org/10.1016/j.jaad.2017.08.062
45 https://doi.org/10.1016/j.jid.2018.05.027
46 https://doi.org/10.1016/j.pharmthera.2012.12.007
47 https://doi.org/10.1016/j.pharmthera.2017.03.007
48 https://doi.org/10.1016/s1074-7613(00)80180-6
49 https://doi.org/10.1046/j.1087-0024.2003.00807.x
50 https://doi.org/10.1053/meta.2001.25592
51 https://doi.org/10.1073/pnas.0506580102
52 https://doi.org/10.1086/519795
53 https://doi.org/10.1089/aid.2013.0197
54 https://doi.org/10.1093/bioinformatics/btp616
55 https://doi.org/10.1093/bioinformatics/btq340
56 https://doi.org/10.1093/bioinformatics/bts090
57 https://doi.org/10.1093/bioinformatics/btw624
58 https://doi.org/10.1093/nar/gkg509
59 https://doi.org/10.1093/nar/gky310
60 https://doi.org/10.1111/bjd.14535
61 https://doi.org/10.1111/dth.12656
62 https://doi.org/10.1111/exd.13071
63 https://doi.org/10.1111/j.1365-2133.2008.08818.x
64 https://doi.org/10.1111/j.1365-2133.2010.09664.x
65 https://doi.org/10.1111/j.1365-2133.2012.11101.x
66 https://doi.org/10.1111/jocd.12125
67 https://doi.org/10.1124/mol.104.006056
68 https://doi.org/10.1128/mcb.01750-06
69 https://doi.org/10.1182/blood-2003-05-1374
70 https://doi.org/10.1210/en.2003-0192
71 https://doi.org/10.1371/journal.pgen.1004383
72 https://doi.org/10.1371/journal.pone.0064683
73 https://doi.org/10.2174/1389200216666150206130058
74 https://doi.org/10.4103/0378-6323.152284
75 schema:datePublished 2019-12
76 schema:datePublishedReg 2019-12-01
77 schema:description Frontal fibrosing alopecia (FFA) is a recently described inflammatory and scarring type of hair loss affecting almost exclusively women. Despite a dramatic recent increase in incidence the aetiopathogenesis of FFA remains unknown. We undertake genome-wide association studies in females from a UK cohort, comprising 844 cases and 3,760 controls, a Spanish cohort of 172 cases and 385 controls, and perform statistical meta-analysis. We observe genome-wide significant association with FFA at four genomic loci: 2p22.2, 6p21.1, 8q24.22 and 15q2.1. Within the 6p21.1 locus, fine-mapping indicates that the association is driven by the HLA-B*07:02 allele. At 2p22.1, we implicate a putative causal missense variant in CYP1B1, encoding the homonymous xenobiotic- and hormone-processing enzyme. Transcriptomic analysis of affected scalp tissue highlights overrepresentation of transcripts encoding components of innate and adaptive immune response pathways. These findings provide insight into disease pathogenesis and characterise FFA as a genetically predisposed immuno-inflammatory disorder driven by HLA-B*07:02.
78 schema:genre research_article
79 schema:inLanguage en
80 schema:isAccessibleForFree true
81 schema:isPartOf N7494b04c081545de9d5d3ca147ebc4e0
82 Nbc9ca24777134c3faf0ecd74e243ad28
83 sg:journal.1043282
84 schema:name Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02
85 schema:pagination 1150
86 schema:productId N17cbdfa00e6c461aa81e4fc0284f5af3
87 N3360aaae59e44668904e3544a565bfc0
88 N6c27ee9aaca44c1bb0e04582e77e2aa2
89 Ncedad93933ae42febd87c6af5a7a34bf
90 Ne55cb9c4403041e09dcc6f3ea93df0d8
91 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112641448
92 https://doi.org/10.1038/s41467-019-09117-w
93 schema:sdDatePublished 2019-04-11T13:59
94 schema:sdLicense https://scigraph.springernature.com/explorer/license/
95 schema:sdPublisher N96cf347f24b7411585381fa165897aa2
96 schema:url https://www.nature.com/articles/s41467-019-09117-w
97 sgo:license sg:explorer/license/
98 sgo:sdDataset articles
99 rdf:type schema:ScholarlyArticle
100 N0014842752464db0a3de6069e12035ea schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
101 schema:familyName Watt
102 schema:givenName Fiona M.
103 rdf:type schema:Person
104 N0393329cbf88477182a3dec91661ff6e schema:affiliation https://www.grid.ac/institutes/grid.426108.9
105 schema:familyName Jones
106 schema:givenName Jennifer
107 rdf:type schema:Person
108 N04c8f338846842a98a90ea44d146417d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Humans
110 rdf:type schema:DefinedTerm
111 N0657e005010548719e0a00db1b47bb6b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Genome, Human
113 rdf:type schema:DefinedTerm
114 N09ea5c7c7b104d42b68990c6b61a16b4 schema:affiliation https://www.grid.ac/institutes/grid.420545.2
115 schema:familyName Wood
116 schema:givenName Kristie
117 rdf:type schema:Person
118 N0a65ef3e86f040c6a9c4cd7aa427d77f schema:name The London Skin and Hair Clinic, WC1V 7DN, London, UK
119 rdf:type schema:Organization
120 N0b6c7a3cfa5e4a6994ba5361fd5b2198 schema:affiliation https://www.grid.ac/institutes/grid.1008.9
121 schema:familyName Sinclair
122 schema:givenName Rodney
123 rdf:type schema:Person
124 N0ba5dd543ae84b0096941fbfbaac61ad rdf:first N158ab821881440bc804787b7d64aa7aa
125 rdf:rest N76c834852c5143088f3ad75c1d23af81
126 N0cc963027bfe4460a6a049426383269b rdf:first N439af5c4bc1347248a6baf998243ca5a
127 rdf:rest N1b3f1c0d5eb34d6da3de407cf66076e3
128 N0eb9cc86d02349888a2bf40f35c438cf rdf:first Nf21f2932c01a472a9a7354c5428a1067
129 rdf:rest N19fdc40a6bc14091b175647fba8be006
130 N0f8f7c5d5f554d5bb4dea2fb303cb230 rdf:first Nbce977ffc31f45ab908c893e0d1cbd59
131 rdf:rest Na7678c94c18f44e594d973b8b7faaecc
132 N0fa19b8e0bfb4340898fb7ff18b8d248 schema:name Alan Lyell Centre for Dermatology, Queen Elizabeth University Hospital, G51 4TF, Glasgow, UK
133 rdf:type schema:Organization
134 N1013d852ea0a49bcbc22c633f5c81409 rdf:first N944dd55c266140169a22ff5e37fad88f
135 rdf:rest N8b9b118f5ce7410f9f8c2e1bf1dadfec
136 N121c2edcd9f745d0a03e03d86dd9a006 rdf:first Nd9c39795d790410bb3520c834333fc51
137 rdf:rest N79efecf264324641937c608f3aea2c1b
138 N134a96e36d224ccfb70207e99d127ef7 rdf:first N631542e18eb74c00b08ab189190283ea
139 rdf:rest Nbdb330aa2f15441d92ee9ad5f22715a1
140 N13b50b0513384800a9e3ce83c242649f rdf:first N4df7bc2b508840378e66ce2138690942
141 rdf:rest N82be4c7ada86440ebc847fec8fcb86d6
142 N14f36e18dad242ad9f10639257fbdf5c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Case-Control Studies
144 rdf:type schema:DefinedTerm
145 N158ab821881440bc804787b7d64aa7aa schema:affiliation https://www.grid.ac/institutes/grid.430506.4
146 schema:familyName Ardern-Jones
147 schema:givenName Michael
148 rdf:type schema:Person
149 N161165167d7a46f8a45d171389d86728 schema:affiliation https://www.grid.ac/institutes/grid.417250.5
150 schema:familyName Banfield
151 schema:givenName Cedric
152 rdf:type schema:Person
153 N17cbdfa00e6c461aa81e4fc0284f5af3 schema:name readcube_id
154 schema:value 485852d12a595384ea983422107dbad520bac3acaa22e9ecdb6d013aac08b9dc
155 rdf:type schema:PropertyValue
156 N18836fe57e834bdaace6cbb9360b3b33 schema:name Alan Lyell Centre for Dermatology, Queen Elizabeth University Hospital, G51 4TF, Glasgow, UK
157 rdf:type schema:Organization
158 N18edf8d194604e2b83bb93e10154ad74 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Female
160 rdf:type schema:DefinedTerm
161 N192ebb154d554aac991de1b59bc233dc schema:affiliation https://www.grid.ac/institutes/grid.414651.3
162 schema:familyName Perez
163 schema:givenName Nerea Ormaechea
164 rdf:type schema:Person
165 N19fdc40a6bc14091b175647fba8be006 rdf:first Ne2eaf45d90404f559597f6cf70d449cb
166 rdf:rest N8c3d1f85e28f4f639d220d0dcff4ca2f
167 N1b3f1c0d5eb34d6da3de407cf66076e3 rdf:first N161165167d7a46f8a45d171389d86728
168 rdf:rest N13b50b0513384800a9e3ce83c242649f
169 N1c9a9fd6f1834d21bd51b3103e378808 rdf:first Nc4535344470f4640963ae7bd90964712
170 rdf:rest N0cc963027bfe4460a6a049426383269b
171 N1dfd895cd1d84669856fb1e27c5690cf rdf:first N638ec83d19064d829b9d2ef9a9019700
172 rdf:rest Nf2f6660717fb440fa38436ea65c1d67c
173 N1e1b54e038d44a29947a0ba6d99efe7b schema:affiliation https://www.grid.ac/institutes/grid.417895.6
174 schema:familyName Ali
175 schema:givenName Iaisha
176 rdf:type schema:Person
177 N1eb3739afc3443388499b2815749e475 rdf:first Nda45ee024c7a4a3ca10a617fbb05c727
178 rdf:rest Nb71c90fa539d4eeebeda9407204b0e26
179 N23b86600ab4d476ba372bdd330bae292 rdf:first N09ea5c7c7b104d42b68990c6b61a16b4
180 rdf:rest N9baad0822d3b4a479043e023a41e94d7
181 N2549bb344420498da9295a81f1ccec76 schema:affiliation https://www.grid.ac/institutes/grid.410725.5
182 schema:familyName Farrant
183 schema:givenName Paul
184 rdf:type schema:Person
185 N2572c7e13b854c6b8d46e444c1d1b25e schema:affiliation https://www.grid.ac/institutes/grid.413824.8
186 schema:familyName Cooke
187 schema:givenName Nicola
188 rdf:type schema:Person
189 N263707e61726458bb38751465f280344 rdf:first N5624c1b54b904c41a2e96cdc21be830c
190 rdf:rest N9901e88c2ac0423dbf3f8c18ea7ae849
191 N29353386656145699d9d4e581c9cb42c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
192 schema:name Genetic Predisposition to Disease
193 rdf:type schema:DefinedTerm
194 N2aa06d826ea648d38a7df78a82534d9c rdf:first Nfa3e2612e72445ffa5576de4dfcb627a
195 rdf:rest Nd5c56e0083fd43368d27f95308e250b9
196 N2b3b942fbbac4692b85f56787a578f1a schema:name Department of Dermatology, Kingston Hospital NHS Foundation Trust, KT2 7QB, Kingston-upon-Thames, UK
197 rdf:type schema:Organization
198 N2cc053eeaaa249a4a912339a9f7e7a1d rdf:first N0014842752464db0a3de6069e12035ea
199 rdf:rest Na9da2b6d1c4d4716b04b8cbfa2e9e59e
200 N2f1b78a8e0574ce8882b4bf1eb386a8e schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
201 schema:familyName McGrath
202 schema:givenName John A.
203 rdf:type schema:Person
204 N3360aaae59e44668904e3544a565bfc0 schema:name dimensions_id
205 schema:value pub.1112641448
206 rdf:type schema:PropertyValue
207 N36a284a1fe464219944088a5c197959f schema:affiliation https://www.grid.ac/institutes/grid.416126.6
208 schema:familyName McDonagh
209 schema:givenName Andrew
210 rdf:type schema:Person
211 N38739c3b787d4809b90e24803d7efae7 rdf:first Ncf1ac8465f9e4696bf3a35eb16fd1a0e
212 rdf:rest N3a3f071bc8244c8e9046fa527b1f6868
213 N387cd732d86942da8820e9477df79bee schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
214 schema:familyName Tziotzios
215 schema:givenName Christos
216 rdf:type schema:Person
217 N3a3f071bc8244c8e9046fa527b1f6868 rdf:first Ncd18f693e7b541678973ffc522485ebb
218 rdf:rest Nb202f527f5194583a6a689be21dc7959
219 N3d8330045d86497f87ab5477b7955578 schema:affiliation https://www.grid.ac/institutes/grid.420545.2
220 schema:familyName de Rinaldis
221 schema:givenName Emanuele
222 rdf:type schema:Person
223 N417d97bbcfcc444abeeda5d01c6a8795 schema:affiliation Nd0c97d692a2f49a9af638b7700af8139
224 schema:familyName Estivill
225 schema:givenName Xavier
226 rdf:type schema:Person
227 N4257698a1abd4933ab1dbddc34ec9eee rdf:first N84877fb530fe488a896511d5c885e941
228 rdf:rest N4a0ddd70bb9b4f6da42e196a4cbbf1b1
229 N439af5c4bc1347248a6baf998243ca5a schema:affiliation https://www.grid.ac/institutes/grid.120073.7
230 schema:familyName Atkar
231 schema:givenName Ravinder
232 rdf:type schema:Person
233 N44d94194ce084ff1970b5a5ac12d84fd schema:affiliation https://www.grid.ac/institutes/grid.410421.2
234 schema:familyName de Berker
235 schema:givenName David
236 rdf:type schema:Person
237 N4500172c5e4e433d90bc71736c8d9a8d schema:name Alan Lyell Centre for Dermatology, Queen Elizabeth University Hospital, G51 4TF, Glasgow, UK
238 rdf:type schema:Organization
239 N45bbd0a7358c4392b28b3f870bcc4192 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
240 schema:familyName Simpson
241 schema:givenName Michael A.
242 rdf:type schema:Person
243 N493f5f18120c4947aa2e6f85f5dccc42 schema:affiliation https://www.grid.ac/institutes/grid.16463.36
244 schema:familyName Dlova
245 schema:givenName Ncoza C.
246 rdf:type schema:Person
247 N49ba300a022644dfadb0aa40d356a066 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
248 schema:name Gene Expression
249 rdf:type schema:DefinedTerm
250 N4a0ddd70bb9b4f6da42e196a4cbbf1b1 rdf:first N6aedc8bb63354d81b17a7f14cbb08584
251 rdf:rest Nc721a629db05484dadf52d991f0e02a4
252 N4b8c684bd48d4fe285e43f72c60d075d schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
253 schema:familyName Fenton
254 schema:givenName David A.
255 rdf:type schema:Person
256 N4df7bc2b508840378e66ce2138690942 schema:affiliation https://www.grid.ac/institutes/grid.419248.2
257 schema:familyName Alexandroff
258 schema:givenName Anton
259 rdf:type schema:Person
260 N4e95f3395cbb432eaf785ce8c23ad9a1 rdf:first Ne6b2ecb3ec654aefae5e1f5e7dc2d49d
261 rdf:rest Nbcddd6fc8d89442fb348001048b0d107
262 N4fd0a96989ea474c819b0b56ece95cb4 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
263 schema:familyName Christou
264 schema:givenName Evangelos A. A.
265 rdf:type schema:Person
266 N5146f6b366494812a901c292dec02621 rdf:first Nd15ef720363b47e3aff1fe38c72df5d8
267 rdf:rest Nc3faac9e643846ea80087230ffdff090
268 N523b245faed64324883e57d5eba37772 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
269 schema:name Alopecia
270 rdf:type schema:DefinedTerm
271 N5624c1b54b904c41a2e96cdc21be830c schema:affiliation https://www.grid.ac/institutes/grid.416109.b
272 schema:familyName Kaur
273 schema:givenName Manjit
274 rdf:type schema:Person
275 N58cb7761ff494c62a95094d356a362d1 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
276 schema:familyName Setterfield
277 schema:givenName Jane
278 rdf:type schema:Person
279 N5a50fb7a65924b5cbb78d6a0828f553b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
280 schema:name Polymorphism, Single Nucleotide
281 rdf:type schema:DefinedTerm
282 N5a7920f19fcc4fff95578e68b490c014 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
283 schema:familyName Smith
284 schema:givenName Catherine H.
285 rdf:type schema:Person
286 N5c6006f0f24045229a2f91312264099c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
287 schema:name Adaptive Immunity
288 rdf:type schema:DefinedTerm
289 N5d3f3b9ed9b640cc8105580f0190760a schema:affiliation https://www.grid.ac/institutes/grid.420545.2
290 schema:familyName Curtis
291 schema:givenName Charles J.
292 rdf:type schema:Person
293 N5db302c7919c473e82288a32db8a05f0 rdf:first Nf4b1daeef9f04d7eb17b2ccc02583f45
294 rdf:rest N134a96e36d224ccfb70207e99d127ef7
295 N5e2615b54f3942edb793d107c21bc432 schema:affiliation https://www.grid.ac/institutes/grid.418709.3
296 schema:familyName Mitchell
297 schema:givenName Charles
298 rdf:type schema:Person
299 N5ec8e08127284fd79b44d8988cfc23a3 rdf:first N2572c7e13b854c6b8d46e444c1d1b25e
300 rdf:rest N1dfd895cd1d84669856fb1e27c5690cf
301 N6033121778a5483a87b00f95c764751e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
302 schema:name Cytochrome P-450 CYP1B1
303 rdf:type schema:DefinedTerm
304 N63049063d6ff457ab65052a08ad9edeb schema:affiliation https://www.grid.ac/institutes/grid.420545.2
305 schema:familyName Pramanik
306 schema:givenName Rashida
307 rdf:type schema:Person
308 N631542e18eb74c00b08ab189190283ea schema:affiliation https://www.grid.ac/institutes/grid.240367.4
309 schema:familyName Page
310 schema:givenName Melanie
311 rdf:type schema:Person
312 N638ec83d19064d829b9d2ef9a9019700 schema:affiliation https://www.grid.ac/institutes/grid.413818.7
313 schema:familyName Goodfield
314 schema:givenName Mark
315 rdf:type schema:Person
316 N64e41c6a1daf4472827692a2eef807a1 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
317 schema:familyName Baudry
318 schema:givenName David
319 rdf:type schema:Person
320 N67ccda886e3041eaadf678b9878b9c61 rdf:first N6dbc05d3508545eab89efdd30a4cc96d
321 rdf:rest N85641cf92206498dbaca69a7b3bfa10b
322 N68b96b33653844b79102f51ff9931109 rdf:first N417d97bbcfcc444abeeda5d01c6a8795
323 rdf:rest N85a2500ebfca4cdd8c044bd45d5ab8b0
324 N6968fea15e86413d8727c2b31499e037 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
325 schema:familyName Petridis
326 schema:givenName Christos
327 rdf:type schema:Person
328 N6a5ebe5526f94bce9c699ada5836c4e5 rdf:first N6968fea15e86413d8727c2b31499e037
329 rdf:rest Ne22e5ee2aa8c4e54a231468c80a8bc42
330 N6aedc8bb63354d81b17a7f14cbb08584 schema:affiliation N4500172c5e4e433d90bc71736c8d9a8d
331 schema:familyName Cunningham
332 schema:givenName Fiona
333 rdf:type schema:Person
334 N6c27250208f84a56aedf76ed089afab1 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
335 schema:familyName Barker
336 schema:givenName Jonathan N.
337 rdf:type schema:Person
338 N6c27ee9aaca44c1bb0e04582e77e2aa2 schema:name nlm_unique_id
339 schema:value 101528555
340 rdf:type schema:PropertyValue
341 N6cf72148bef84e679bee5b1be9bc8d4c rdf:first Ne116523ac0e141aaab57dfe5a9997679
342 rdf:rest N68b96b33653844b79102f51ff9931109
343 N6dbc05d3508545eab89efdd30a4cc96d schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
344 schema:familyName Ainali
345 schema:givenName Chrysanthi
346 rdf:type schema:Person
347 N70ab06e2dd6e487d8c7f2550de5750d9 rdf:first Ne0e1b42324ad4c7da419e90ec71fb300
348 rdf:rest N1013d852ea0a49bcbc22c633f5c81409
349 N7494b04c081545de9d5d3ca147ebc4e0 schema:issueNumber 1
350 rdf:type schema:PublicationIssue
351 N74c17c6dd9194d25960507a035cd966c schema:affiliation https://www.grid.ac/institutes/grid.412346.6
352 schema:familyName Harries
353 schema:givenName Matthew
354 rdf:type schema:Person
355 N75e0dd84803c4128bfc12d7c29aadd3c rdf:first Na7eaec3bc90c448299536d169de76ccc
356 rdf:rest N1eb3739afc3443388499b2815749e475
357 N76c834852c5143088f3ad75c1d23af81 rdf:first N5e2615b54f3942edb793d107c21bc432
358 rdf:rest N1c9a9fd6f1834d21bd51b3103e378808
359 N76cf571511bc4a018f04464424bde7d5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
360 schema:name Cohort Studies
361 rdf:type schema:DefinedTerm
362 N77bd1ad371874aa5a0e75538ac37d178 schema:affiliation https://www.grid.ac/institutes/grid.416041.6
363 schema:familyName Jolliffe
364 schema:givenName Victoria
365 rdf:type schema:Person
366 N77d8f3a7e71a4ce682b8fd7085c2a04d schema:affiliation https://www.grid.ac/institutes/grid.428852.1
367 schema:familyName Patel
368 schema:givenName Girish K.
369 rdf:type schema:Person
370 N7915122981f6427d882ae0f70bd8d126 schema:affiliation https://www.grid.ac/institutes/grid.434530.5
371 schema:familyName Takwale
372 schema:givenName Anita
373 rdf:type schema:Person
374 N79efecf264324641937c608f3aea2c1b rdf:first N7915122981f6427d882ae0f70bd8d126
375 rdf:rest N7da8f49ab5e345b2912cd02278d6c876
376 N7da8f49ab5e345b2912cd02278d6c876 rdf:first N98cf31c8ba924182a611e2817ccf731f
377 rdf:rest N4e95f3395cbb432eaf785ce8c23ad9a1
378 N7ef0d94e4f1040a4b123f1c86127a903 rdf:first N58cb7761ff494c62a95094d356a362d1
379 rdf:rest Nb48f6609dad44873820a82e5cada33dd
380 N7fdf0d314915452d84933aad0c378fdd rdf:first N36a284a1fe464219944088a5c197959f
381 rdf:rest N5146f6b366494812a901c292dec02621
382 N82be4c7ada86440ebc847fec8fcb86d6 rdf:first Nd8cb11376faa4e1da5b0a92531655629
383 rdf:rest N38739c3b787d4809b90e24803d7efae7
384 N84877fb530fe488a896511d5c885e941 schema:affiliation https://www.grid.ac/institutes/grid.414254.2
385 schema:familyName Palamaras
386 schema:givenName Ioulios
387 rdf:type schema:Person
388 N84f8d095c336432eb8aab9fd12d9d56a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
389 schema:name Transcriptome
390 rdf:type schema:DefinedTerm
391 N84fcd394d9d94f73809a274f1844390d rdf:first N5d3f3b9ed9b640cc8105580f0190760a
392 rdf:rest N91bea0c365b74b75be84d29e059c996a
393 N8546de75cd37414abc12d9353591c353 rdf:first N6c27250208f84a56aedf76ed089afab1
394 rdf:rest Nac752cc9d27847d2b40486fa77db0148
395 N85641cf92206498dbaca69a7b3bfa10b rdf:first Na24afdce5b1e4686be7d6bfb51e5acd9
396 rdf:rest N75e0dd84803c4128bfc12d7c29aadd3c
397 N85a2500ebfca4cdd8c044bd45d5ab8b0 rdf:first N86289c5f934e4bd4b466e1ea06748e85
398 rdf:rest Nba281d4fda144f4bb622dd24e9543f5c
399 N86289c5f934e4bd4b466e1ea06748e85 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
400 schema:familyName Stefanato
401 schema:givenName Catherine M.
402 rdf:type schema:Person
403 N8b9b118f5ce7410f9f8c2e1bf1dadfec rdf:first Nfc47eecb7cfd44d6becb3c45ee43ac30
404 rdf:rest N969696cfe66b47b783f8fc85ad490172
405 N8c3d1f85e28f4f639d220d0dcff4ca2f rdf:first N93d143ed9c9e4aa6938fd19ba8d20e24
406 rdf:rest N5ec8e08127284fd79b44d8988cfc23a3
407 N8c64a06d9b6c49d9ac04c26c3271082a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
408 schema:name Genome-Wide Association Study
409 rdf:type schema:DefinedTerm
410 N8d43b17dcdca4ec7a2d7ec74671090b4 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
411 schema:familyName Dand
412 schema:givenName Nick
413 rdf:type schema:Person
414 N906cee532ab1462f9efae45578f2c420 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
415 schema:name Genetic Loci
416 rdf:type schema:DefinedTerm
417 N91bea0c365b74b75be84d29e059c996a rdf:first N3d8330045d86497f87ab5477b7955578
418 rdf:rest Nc81778b8dac94e4884f04406c40478ac
419 N93d143ed9c9e4aa6938fd19ba8d20e24 schema:affiliation https://www.grid.ac/institutes/grid.416232.0
420 schema:familyName Armstrong
421 schema:givenName Keith
422 rdf:type schema:Person
423 N944dd55c266140169a22ff5e37fad88f schema:affiliation https://www.grid.ac/institutes/grid.429438.0
424 schema:familyName Michelotti
425 schema:givenName Gregory A.
426 rdf:type schema:Person
427 N969696cfe66b47b783f8fc85ad490172 rdf:first N4fd0a96989ea474c819b0b56ece95cb4
428 rdf:rest N84fcd394d9d94f73809a274f1844390d
429 N96cf347f24b7411585381fa165897aa2 schema:name Springer Nature - SN SciGraph project
430 rdf:type schema:Organization
431 N98cf31c8ba924182a611e2817ccf731f schema:affiliation N2b3b942fbbac4692b85f56787a578f1a
432 schema:familyName Rao
433 schema:givenName Archana
434 rdf:type schema:Person
435 N9901e88c2ac0423dbf3f8c18ea7ae849 rdf:first N2549bb344420498da9295a81f1ccec76
436 rdf:rest N7fdf0d314915452d84933aad0c378fdd
437 N99c8ba13baa94bcabdee450cf2c954f2 rdf:first N45bbd0a7358c4392b28b3f870bcc4192
438 rdf:rest Nddd9934c144448ccbdd21e5e87b1c338
439 N9a1a80acd01a484397842d0ee332e8ad rdf:first Nbf0f9335950143de8b8b1f1d1452c240
440 rdf:rest N6cf72148bef84e679bee5b1be9bc8d4c
441 N9baad0822d3b4a479043e023a41e94d7 rdf:first Ndfd79e09b4a14f3cb71ac34edebfa7db
442 rdf:rest N70ab06e2dd6e487d8c7f2550de5750d9
443 N9f1e4e199c1f4d54b264d65c400d60f0 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
444 schema:familyName Lewis
445 schema:givenName Fiona
446 rdf:type schema:Person
447 Na05ba85a2ef74e21a69a9472726294e1 schema:affiliation https://www.grid.ac/institutes/grid.439641.d
448 schema:familyName Man
449 schema:givenName Irene
450 rdf:type schema:Person
451 Na0d37cb2d29f4c82904561fcf589fc44 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
452 schema:familyName Flohr
453 schema:givenName Carsten
454 rdf:type schema:Person
455 Na24afdce5b1e4686be7d6bfb51e5acd9 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
456 schema:familyName Saklatvala
457 schema:givenName Jake R.
458 rdf:type schema:Person
459 Na64bf23f4b954c52b565fe0c834254cb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
460 schema:name Immunity, Innate
461 rdf:type schema:DefinedTerm
462 Na7678c94c18f44e594d973b8b7faaecc rdf:first N493f5f18120c4947aa2e6f85f5dccc42
463 rdf:rest N7ef0d94e4f1040a4b123f1c86127a903
464 Na7eaec3bc90c448299536d169de76ccc schema:affiliation https://www.grid.ac/institutes/grid.420545.2
465 schema:familyName Pullabhatla
466 schema:givenName Venu
467 rdf:type schema:Person
468 Na9da2b6d1c4d4716b04b8cbfa2e9e59e rdf:first N5a7920f19fcc4fff95578e68b490c014
469 rdf:rest N8546de75cd37414abc12d9353591c353
470 Naa9ae2139ce64fa58992e1ccb9eae753 schema:affiliation https://www.grid.ac/institutes/grid.419651.e
471 schema:familyName Molina-Ruiz
472 schema:givenName Ana Maria
473 rdf:type schema:Person
474 Nab73bab835c044cbb282e62b7d870f02 schema:affiliation N0fa19b8e0bfb4340898fb7ff18b8d248
475 schema:familyName Parkins
476 schema:givenName Gregory
477 rdf:type schema:Person
478 Nac752cc9d27847d2b40486fa77db0148 rdf:first N4b8c684bd48d4fe285e43f72c60d075d
479 rdf:rest N99c8ba13baa94bcabdee450cf2c954f2
480 Nadc79817a4034d51ac21340c4c8d5628 rdf:first N1e1b54e038d44a29947a0ba6d99efe7b
481 rdf:rest N0ba5dd543ae84b0096941fbfbaac61ad
482 Naf1be5aa0dbf4b8cac9bb494ec30a612 schema:affiliation https://www.grid.ac/institutes/grid.420545.2
483 schema:familyName Saxena
484 schema:givenName Alka
485 rdf:type schema:Person
486 Nb0a56f31808142a5a942f65b9b3828e6 rdf:first Nf1492efe13d445989b2db07f126f2d5d
487 rdf:rest N2cc053eeaaa249a4a912339a9f7e7a1d
488 Nb202f527f5194583a6a689be21dc7959 rdf:first Naa9ae2139ce64fa58992e1ccb9eae753
489 rdf:rest Nf2d8cd47fc4e45d3857e3ecacc4a9a01
490 Nb48f6609dad44873820a82e5cada33dd rdf:first N9f1e4e199c1f4d54b264d65c400d60f0
491 rdf:rest N9a1a80acd01a484397842d0ee332e8ad
492 Nb71c90fa539d4eeebeda9407204b0e26 rdf:first N63049063d6ff457ab65052a08ad9edeb
493 rdf:rest Ne752fb0cdbc64315865599240776f2ea
494 Nba281d4fda144f4bb622dd24e9543f5c rdf:first Na0d37cb2d29f4c82904561fcf589fc44
495 rdf:rest Nb0a56f31808142a5a942f65b9b3828e6
496 Nbc9ca24777134c3faf0ecd74e243ad28 schema:volumeNumber 10
497 rdf:type schema:PublicationVolume
498 Nbcddd6fc8d89442fb348001048b0d107 rdf:first N0b6c7a3cfa5e4a6994ba5361fd5b2198
499 rdf:rest N0f8f7c5d5f554d5bb4dea2fb303cb230
500 Nbce977ffc31f45ab908c893e0d1cbd59 schema:affiliation N0a65ef3e86f040c6a9c4cd7aa427d77f
501 schema:familyName Wade
502 schema:givenName Martin S.
503 rdf:type schema:Person
504 Nbdb330aa2f15441d92ee9ad5f22715a1 rdf:first Nf271f9490e384b249ece073407ce31b4
505 rdf:rest N0eb9cc86d02349888a2bf40f35c438cf
506 Nbf0f9335950143de8b8b1f1d1452c240 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
507 schema:familyName Bhargava
508 schema:givenName Kapil
509 rdf:type schema:Person
510 Nbf5fb21508a74a60807534dda2d1a978 rdf:first N44d94194ce084ff1970b5a5ac12d84fd
511 rdf:rest N121c2edcd9f745d0a03e03d86dd9a006
512 Nc3faac9e643846ea80087230ffdff090 rdf:first N0393329cbf88477182a3dec91661ff6e
513 rdf:rest Nca965dcff7894252968e4d5f3d00f957
514 Nc4535344470f4640963ae7bd90964712 schema:affiliation https://www.grid.ac/institutes/grid.120073.7
515 schema:familyName Burrows
516 schema:givenName Nigel
517 rdf:type schema:Person
518 Nc721a629db05484dadf52d991f0e02a4 rdf:first Nab73bab835c044cbb282e62b7d870f02
519 rdf:rest N263707e61726458bb38751465f280344
520 Nc81778b8dac94e4884f04406c40478ac rdf:first Naf1be5aa0dbf4b8cac9bb494ec30a612
521 rdf:rest N2aa06d826ea648d38a7df78a82534d9c
522 Nca965dcff7894252968e4d5f3d00f957 rdf:first N77bd1ad371874aa5a0e75538ac37d178
523 rdf:rest Nadc79817a4034d51ac21340c4c8d5628
524 Ncb951f3d04f64c25b7974bb1076a6887 rdf:first N387cd732d86942da8820e9477df79bee
525 rdf:rest N6a5ebe5526f94bce9c699ada5836c4e5
526 Ncd18f693e7b541678973ffc522485ebb schema:affiliation https://www.grid.ac/institutes/grid.411347.4
527 schema:familyName Vañó-Galván
528 schema:givenName Sergio
529 rdf:type schema:Person
530 Ncedad93933ae42febd87c6af5a7a34bf schema:name doi
531 schema:value 10.1038/s41467-019-09117-w
532 rdf:type schema:PropertyValue
533 Ncf1ac8465f9e4696bf3a35eb16fd1a0e schema:affiliation https://www.grid.ac/institutes/grid.418709.3
534 schema:familyName Cooper
535 schema:givenName Hywel L.
536 rdf:type schema:Person
537 Nd0c97d692a2f49a9af638b7700af8139 schema:name Genetics Unit, Dexeus Women’s Health, 08028, Barcelona, Spain
538 rdf:type schema:Organization
539 Nd15ef720363b47e3aff1fe38c72df5d8 schema:affiliation https://www.grid.ac/institutes/grid.416126.6
540 schema:familyName Messenger
541 schema:givenName Andrew
542 rdf:type schema:Person
543 Nd5c56e0083fd43368d27f95308e250b9 rdf:first N74c17c6dd9194d25960507a035cd966c
544 rdf:rest N4257698a1abd4933ab1dbddc34ec9eee
545 Nd8a319332f0740aa9d8127d0aa6eb8ab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
546 schema:name HLA-B7 Antigen
547 rdf:type schema:DefinedTerm
548 Nd8cb11376faa4e1da5b0a92531655629 schema:affiliation https://www.grid.ac/institutes/grid.415719.f
549 schema:familyName Champagne
550 schema:givenName Caroline
551 rdf:type schema:Person
552 Nd9c39795d790410bb3520c834333fc51 schema:affiliation https://www.grid.ac/institutes/grid.410421.2
553 schema:familyName Dunnill
554 schema:givenName Giles
555 rdf:type schema:Person
556 Nda45ee024c7a4a3ca10a617fbb05c727 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
557 schema:familyName Onoufriadis
558 schema:givenName Alexandros
559 rdf:type schema:Person
560 Nddd9934c144448ccbdd21e5e87b1c338 rdf:first N2f1b78a8e0574ce8882b4bf1eb386a8e
561 rdf:rest rdf:nil
562 Ndfd79e09b4a14f3cb71ac34edebfa7db schema:affiliation https://www.grid.ac/institutes/grid.425213.3
563 schema:familyName Liu
564 schema:givenName Lu
565 rdf:type schema:Person
566 Ne0e1b42324ad4c7da419e90ec71fb300 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
567 schema:familyName Seegobin
568 schema:givenName Seth
569 rdf:type schema:Person
570 Ne116523ac0e141aaab57dfe5a9997679 schema:affiliation https://www.grid.ac/institutes/grid.439369.2
571 schema:familyName Kirkpatrick
572 schema:givenName Niall
573 rdf:type schema:Person
574 Ne22e5ee2aa8c4e54a231468c80a8bc42 rdf:first N8d43b17dcdca4ec7a2d7ec74671090b4
575 rdf:rest N67ccda886e3041eaadf678b9878b9c61
576 Ne2eaf45d90404f559597f6cf70d449cb schema:affiliation https://www.grid.ac/institutes/grid.412907.9
577 schema:familyName Wahie
578 schema:givenName Shyamal
579 rdf:type schema:Person
580 Ne55cb9c4403041e09dcc6f3ea93df0d8 schema:name pubmed_id
581 schema:value 30850646
582 rdf:type schema:PropertyValue
583 Ne6b2ecb3ec654aefae5e1f5e7dc2d49d schema:affiliation https://www.grid.ac/institutes/grid.419334.8
584 schema:familyName Siah
585 schema:givenName Tee-Wei
586 rdf:type schema:Person
587 Ne752fb0cdbc64315865599240776f2ea rdf:first N64e41c6a1daf4472827692a2eef807a1
588 rdf:rest Nf1d0a88b4e6a46b8866344334359846c
589 Nf1492efe13d445989b2db07f126f2d5d schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
590 schema:familyName Spector
591 schema:givenName Timothy
592 rdf:type schema:Person
593 Nf1d0a88b4e6a46b8866344334359846c rdf:first Nff1932e5dd194920ae0f796fbe3deb37
594 rdf:rest N23b86600ab4d476ba372bdd330bae292
595 Nf21f2932c01a472a9a7354c5428a1067 schema:affiliation https://www.grid.ac/institutes/grid.415547.6
596 schema:familyName Mowbray
597 schema:givenName Megan
598 rdf:type schema:Person
599 Nf271f9490e384b249ece073407ce31b4 schema:affiliation https://www.grid.ac/institutes/grid.416266.1
600 schema:familyName Bryden
601 schema:givenName Alyson
602 rdf:type schema:Person
603 Nf2d8cd47fc4e45d3857e3ecacc4a9a01 rdf:first N192ebb154d554aac991de1b59bc233dc
604 rdf:rest Nf9b58ae5abfe4a3e8b53a5981a948d75
605 Nf2f6660717fb440fa38436ea65c1d67c rdf:first Na05ba85a2ef74e21a69a9472726294e1
606 rdf:rest Nbf5fb21508a74a60807534dda2d1a978
607 Nf4b1daeef9f04d7eb17b2ccc02583f45 schema:affiliation https://www.grid.ac/institutes/grid.240367.4
608 schema:familyName Macbeth
609 schema:givenName Abby
610 rdf:type schema:Person
611 Nf9b58ae5abfe4a3e8b53a5981a948d75 rdf:first N77d8f3a7e71a4ce682b8fd7085c2a04d
612 rdf:rest N5db302c7919c473e82288a32db8a05f0
613 Nfa3e2612e72445ffa5576de4dfcb627a schema:affiliation N18836fe57e834bdaace6cbb9360b3b33
614 schema:familyName Holmes
615 schema:givenName Susan
616 rdf:type schema:Person
617 Nfc47eecb7cfd44d6becb3c45ee43ac30 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
618 schema:familyName Lwin
619 schema:givenName Su M.
620 rdf:type schema:Person
621 Nff1932e5dd194920ae0f796fbe3deb37 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
622 schema:familyName Lee
623 schema:givenName Sang Hyuck
624 rdf:type schema:Person
625 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
626 schema:name Biological Sciences
627 rdf:type schema:DefinedTerm
628 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
629 schema:name Genetics
630 rdf:type schema:DefinedTerm
631 sg:journal.1043282 schema:issn 2041-1723
632 schema:name Nature Communications
633 rdf:type schema:Periodical
634 sg:pub.10.1007/s00210-003-0819-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1045914344
635 https://doi.org/10.1007/s00210-003-0819-z
636 rdf:type schema:CreativeWork
637 sg:pub.10.1038/ng.2435 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016174016
638 https://doi.org/10.1038/ng.2435
639 rdf:type schema:CreativeWork
640 sg:pub.10.1038/ng.2653 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032444369
641 https://doi.org/10.1038/ng.2653
642 rdf:type schema:CreativeWork
643 sg:pub.10.1038/ng.2892 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050728268
644 https://doi.org/10.1038/ng.2892
645 rdf:type schema:CreativeWork
646 sg:pub.10.1038/ng.2982 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044995197
647 https://doi.org/10.1038/ng.2982
648 rdf:type schema:CreativeWork
649 sg:pub.10.1038/ng.3211 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044444076
650 https://doi.org/10.1038/ng.3211
651 rdf:type schema:CreativeWork
652 sg:pub.10.1038/srep44005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084131907
653 https://doi.org/10.1038/srep44005
654 rdf:type schema:CreativeWork
655 sg:pub.10.1046/j.1087-0024.2003.00807.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1006039426
656 https://doi.org/10.1046/j.1087-0024.2003.00807.x
657 rdf:type schema:CreativeWork
658 sg:pub.10.1186/1758-2946-2-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050476991
659 https://doi.org/10.1186/1758-2946-2-9
660 rdf:type schema:CreativeWork
661 sg:pub.10.1186/gb-2010-11-12-144 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025477933
662 https://doi.org/10.1186/gb-2010-11-12-144
663 rdf:type schema:CreativeWork
664 sg:pub.10.1186/gb-2010-11-3-r25 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050509557
665 https://doi.org/10.1186/gb-2010-11-3-r25
666 rdf:type schema:CreativeWork
667 https://app.dimensions.ai/details/publication/pub.1079485310 schema:CreativeWork
668 https://doi.org/10.1001/archderm.130.6.770 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054099330
669 rdf:type schema:CreativeWork
670 https://doi.org/10.1001/archderm.1994.01690060100013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006806844
671 rdf:type schema:CreativeWork
672 https://doi.org/10.1002/gepi.20359 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011882893
673 rdf:type schema:CreativeWork
674 https://doi.org/10.1002/path.4233 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048276048
675 rdf:type schema:CreativeWork
676 https://doi.org/10.1016/j.ajhg.2010.11.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009497006
677 rdf:type schema:CreativeWork
678 https://doi.org/10.1016/j.canlet.2014.04.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009126309
679 rdf:type schema:CreativeWork
680 https://doi.org/10.1016/j.ejmech.2017.04.042 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084911469
681 rdf:type schema:CreativeWork
682 https://doi.org/10.1016/j.humimm.2013.07.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036111361
683 rdf:type schema:CreativeWork
684 https://doi.org/10.1016/j.jaad.2009.09.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014259029
685 rdf:type schema:CreativeWork
686 https://doi.org/10.1016/j.jaad.2013.12.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033345938
687 rdf:type schema:CreativeWork
688 https://doi.org/10.1016/j.jaad.2014.05.064 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000129319
689 rdf:type schema:CreativeWork
690 https://doi.org/10.1016/j.jaad.2015.01.057 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025280694
691 rdf:type schema:CreativeWork
692 https://doi.org/10.1016/j.jaad.2017.08.062 schema:sameAs https://app.dimensions.ai/details/publication/pub.1099650298
693 rdf:type schema:CreativeWork
694 https://doi.org/10.1016/j.jid.2018.05.027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1105857642
695 rdf:type schema:CreativeWork
696 https://doi.org/10.1016/j.pharmthera.2012.12.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026929795
697 rdf:type schema:CreativeWork
698 https://doi.org/10.1016/j.pharmthera.2017.03.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084101568
699 rdf:type schema:CreativeWork
700 https://doi.org/10.1016/s1074-7613(00)80180-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020801834
701 rdf:type schema:CreativeWork
702 https://doi.org/10.1046/j.1087-0024.2003.00807.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1006039426
703 rdf:type schema:CreativeWork
704 https://doi.org/10.1053/meta.2001.25592 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006849397
705 rdf:type schema:CreativeWork
706 https://doi.org/10.1073/pnas.0506580102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037705714
707 rdf:type schema:CreativeWork
708 https://doi.org/10.1086/519795 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019061180
709 rdf:type schema:CreativeWork
710 https://doi.org/10.1089/aid.2013.0197 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059226710
711 rdf:type schema:CreativeWork
712 https://doi.org/10.1093/bioinformatics/btp616 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023247882
713 rdf:type schema:CreativeWork
714 https://doi.org/10.1093/bioinformatics/btq340 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047276303
715 rdf:type schema:CreativeWork
716 https://doi.org/10.1093/bioinformatics/bts090 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014257712
717 rdf:type schema:CreativeWork
718 https://doi.org/10.1093/bioinformatics/btw624 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083732273
719 rdf:type schema:CreativeWork
720 https://doi.org/10.1093/nar/gkg509 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002198958
721 rdf:type schema:CreativeWork
722 https://doi.org/10.1093/nar/gky310 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103369702
723 rdf:type schema:CreativeWork
724 https://doi.org/10.1111/bjd.14535 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015814759
725 rdf:type schema:CreativeWork
726 https://doi.org/10.1111/dth.12656 schema:sameAs https://app.dimensions.ai/details/publication/pub.1107293677
727 rdf:type schema:CreativeWork
728 https://doi.org/10.1111/exd.13071 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011421154
729 rdf:type schema:CreativeWork
730 https://doi.org/10.1111/j.1365-2133.2008.08818.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1047542704
731 rdf:type schema:CreativeWork
732 https://doi.org/10.1111/j.1365-2133.2010.09664.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1016173005
733 rdf:type schema:CreativeWork
734 https://doi.org/10.1111/j.1365-2133.2012.11101.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1000537120
735 rdf:type schema:CreativeWork
736 https://doi.org/10.1111/jocd.12125 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012505359
737 rdf:type schema:CreativeWork
738 https://doi.org/10.1124/mol.104.006056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004869238
739 rdf:type schema:CreativeWork
740 https://doi.org/10.1128/mcb.01750-06 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031565298
741 rdf:type schema:CreativeWork
742 https://doi.org/10.1182/blood-2003-05-1374 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017571842
743 rdf:type schema:CreativeWork
744 https://doi.org/10.1210/en.2003-0192 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064246060
745 rdf:type schema:CreativeWork
746 https://doi.org/10.1371/journal.pgen.1004383 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020333172
747 rdf:type schema:CreativeWork
748 https://doi.org/10.1371/journal.pone.0064683 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023672325
749 rdf:type schema:CreativeWork
750 https://doi.org/10.2174/1389200216666150206130058 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069176422
751 rdf:type schema:CreativeWork
752 https://doi.org/10.4103/0378-6323.152284 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030253368
753 rdf:type schema:CreativeWork
754 https://www.grid.ac/institutes/grid.1008.9 schema:alternateName University of Melbourne
755 schema:name Department of Dermatology, University of Melbourne, VIC 3010, Melbourne, Australia
756 rdf:type schema:Organization
757 https://www.grid.ac/institutes/grid.120073.7 schema:alternateName Addenbrooke's Hospital
758 schema:name Department of Dermatology, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust, CB2 0QQ, Cambridge, UK
759 rdf:type schema:Organization
760 https://www.grid.ac/institutes/grid.13097.3c schema:alternateName King's College London
761 schema:name Centre for Stem Cells and Regenerative Medicine, King’s College London, Guy’s Hospital, SE1 9RT, London, UK
762 Department of Dermatopathology, St. John’s Institute of Dermatology, St. Thomas’ Hospital, SE1 7EH, London, UK
763 Department of Medical and Molecular Genetics, King’s College London, Guy’s Hospital, SE1 9RT, London, UK
764 NIHR Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust (SLaM) & Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King’s College London, Denmark Hill Campus, SE5 8EF, London, UK
765 St. John’s Institute of Dermatology, King’s College London, London, Guy’s Hospital, SE1 9RT, London, UK
766 The Department of Twin Research & Genetic Epidemiology, King’s College London, SE1 7EH, London, UK
767 rdf:type schema:Organization
768 https://www.grid.ac/institutes/grid.16463.36 schema:alternateName University of KwaZulu-Natal
769 schema:name Department of Dermatology, School of Clinical Medicine, Nelson R Mandela School of Medicine, 4001, Durban, South Africa
770 rdf:type schema:Organization
771 https://www.grid.ac/institutes/grid.240367.4 schema:alternateName Norfolk and Norwich University Hospitals NHS Foundation Trust
772 schema:name Department of Dermatology, Norfolk & Norwich University Hospitals NHS Foundation Trust, NR4 7UY, Norwich, UK
773 rdf:type schema:Organization
774 https://www.grid.ac/institutes/grid.410421.2 schema:alternateName University Hospitals Bristol NHS Foundation Trust
775 schema:name Department of Dermatology, University Hospitals Bristol NHS Foundation Trust, BS2 8HW, Bristol, UK
776 rdf:type schema:Organization
777 https://www.grid.ac/institutes/grid.410725.5 schema:alternateName Brighton and Sussex University Hospitals NHS Trust
778 schema:name Department of Dermatology, Brighton and Sussex University Hospitals NHS Trust, BN2 3EW, Brighton, UK
779 rdf:type schema:Organization
780 https://www.grid.ac/institutes/grid.411347.4 schema:alternateName Hospital Universitario Ramón y Cajal
781 schema:name Trichology Unit, Dermatology Department, Ramon Y Cajal Hospital, University of Alcala, IRYCIS, 28034, Madrid, Spain
782 rdf:type schema:Organization
783 https://www.grid.ac/institutes/grid.412346.6 schema:alternateName Salford Royal NHS Foundation Trust
784 schema:name The Dermatology Centre, The University of Manchester, Salford Royal NHS Foundation Trust, M6 8HD, Salford, UK
785 rdf:type schema:Organization
786 https://www.grid.ac/institutes/grid.412907.9 schema:alternateName County Durham and Darlington NHS Foundation Trust
787 schema:name Department of Dermatology, County Durham and Darlington NHS Foundation Trust, DL3 6HX, Darlington, UK
788 rdf:type schema:Organization
789 https://www.grid.ac/institutes/grid.413818.7 schema:alternateName Chapel Allerton Hospital
790 schema:name Department of Dermatology, Chapel Allerton Hospital, Leeds teaching Hospitals NHS Trust, LS7 4SA, Leeds, UK
791 rdf:type schema:Organization
792 https://www.grid.ac/institutes/grid.413824.8 schema:alternateName Northern Health and Social Care Trust
793 schema:name Department of Dermatology, Whiteabbey Hospital, Northern Health & Social Care Trust, BT37 9RH, Co Antrim, UK
794 rdf:type schema:Organization
795 https://www.grid.ac/institutes/grid.414254.2 schema:alternateName Barnet Hospital
796 schema:name Department of Dermatology, Barnet General Hospital, Royal Free Foundation Trust, EN5 3DJ, London, UK
797 rdf:type schema:Organization
798 https://www.grid.ac/institutes/grid.414651.3 schema:alternateName Donostia Unibertsitate Ospitalea
799 schema:name Department of Dermatology, Hospital Donostia, 20014, San Sebastian, Spain
800 rdf:type schema:Organization
801 https://www.grid.ac/institutes/grid.415547.6 schema:alternateName Queen Margaret Hospital
802 schema:name Department of Dermatology, Queen Margaret Hospital, KY12 0SU, Dunfermline, UK
803 rdf:type schema:Organization
804 https://www.grid.ac/institutes/grid.415719.f schema:alternateName Churchill Hospital
805 schema:name Department of Dermatology, The Churchill Hospital, OX3 7LE, Oxford, UK
806 rdf:type schema:Organization
807 https://www.grid.ac/institutes/grid.416041.6 schema:alternateName Royal London Hospital
808 schema:name Department of Dermatology, Royal London Hospital, Barts Health NHS Trust, E1 1BB, London, UK
809 rdf:type schema:Organization
810 https://www.grid.ac/institutes/grid.416109.b schema:alternateName Solihull Hospital
811 schema:name Department of Dermatology, Solihull Hospital, B91 2JL, Solihull, UK
812 rdf:type schema:Organization
813 https://www.grid.ac/institutes/grid.416126.6 schema:alternateName Royal Hallamshire Hospital
814 schema:name Department of Dermatology, Royal Hallamshire Hospital, S10 2JF, Sheffield, UK
815 rdf:type schema:Organization
816 https://www.grid.ac/institutes/grid.416232.0 schema:alternateName Royal Victoria Hospital
817 schema:name Department of Dermatology, Royal Victoria Hospital, BT12 6BA, Belfast, UK
818 rdf:type schema:Organization
819 https://www.grid.ac/institutes/grid.416266.1 schema:alternateName Ninewells Hospital
820 schema:name Department of Dermatology, Ninewells Hospital, DD1 9SY, Dundee, UK
821 rdf:type schema:Organization
822 https://www.grid.ac/institutes/grid.417250.5 schema:alternateName Peterborough City Hospital
823 schema:name Department of Dermatology, Peterborough City Hospital, PE3 9GZ, Peterborough, UK
824 rdf:type schema:Organization
825 https://www.grid.ac/institutes/grid.417895.6 schema:alternateName Imperial College Healthcare NHS Trust
826 schema:name Department of Dermatology, Imperial College Healthcare NHS Trust, W12 0HS, London, UK
827 rdf:type schema:Organization
828 https://www.grid.ac/institutes/grid.418709.3 schema:alternateName Portsmouth Hospitals NHS Trust
829 schema:name Department of Dermatology, Portsmouth Hospitals NHS Trust, PO6 3LY, Portsmouth, UK
830 rdf:type schema:Organization
831 https://www.grid.ac/institutes/grid.419248.2 schema:alternateName Leicester Royal Infirmary
832 schema:name Department of Dermatology, University Hospitals of Leicester, Leicester Royal Infirmary, LE3 9QP, Leicester, UK
833 rdf:type schema:Organization
834 https://www.grid.ac/institutes/grid.419334.8 schema:alternateName Royal Victoria Infirmary
835 schema:name Department of Dermatology, Royal Victoria Infirmary, NE1 4LP, Newcastle upon Tyne, UK
836 rdf:type schema:Organization
837 https://www.grid.ac/institutes/grid.419651.e schema:alternateName Hospital Universitario Fundación Jiménez Díaz
838 schema:name Hospital Universitario Fundación Jiménez Díaz, 28040, Madrid, Spain
839 rdf:type schema:Organization
840 https://www.grid.ac/institutes/grid.420545.2 schema:alternateName Guy's and St Thomas' NHS Foundation Trust
841 schema:name UK NIHR GSTFT/KCL Comprehensive Biomedical Research Centre, Guy’s & St. Thomas’ NHS Foundation Trust, SE1 9RT, London, UK
842 rdf:type schema:Organization
843 https://www.grid.ac/institutes/grid.425213.3 schema:alternateName St Thomas' Hospital
844 schema:name National Diagnostic EB Laboratory, St. Thomas Hospital, SE1 7EH, London, UK
845 rdf:type schema:Organization
846 https://www.grid.ac/institutes/grid.426108.9 schema:alternateName Royal Free Hospital
847 schema:name Department of Dermatology, Royal Free Hospital, NW3 2QG, London, UK
848 rdf:type schema:Organization
849 https://www.grid.ac/institutes/grid.428852.1 schema:alternateName Hywel Dda University Health Board
850 schema:name Hywel Dda University Health Board, SA31 3BB, Cardiff, UK
851 rdf:type schema:Organization
852 https://www.grid.ac/institutes/grid.429438.0 schema:alternateName Metabolon (United States)
853 schema:name Metabolon, Inc., 27560, Morrisville, NC, USA
854 rdf:type schema:Organization
855 https://www.grid.ac/institutes/grid.430506.4 schema:alternateName University Hospital Southampton NHS Foundation Trust
856 schema:name Department of Dermatology, University Hospitals Southampton NHS Foundation Trust, SO16 6YD, Southampton, UK
857 rdf:type schema:Organization
858 https://www.grid.ac/institutes/grid.434530.5 schema:alternateName Gloucestershire Hospitals NHS Foundation Trust
859 schema:name Department of Dermatology, Gloucestershire Hospitals NHS Foundation Trust, GL1 3NN, Gloucester, UK
860 rdf:type schema:Organization
861 https://www.grid.ac/institutes/grid.439369.2 schema:alternateName Chelsea and Westminster Hospital
862 schema:name Craniofacial Surgery Unit, Chelsea & Westminster Hospital, SW10 9NH, London, UK
863 rdf:type schema:Organization
864 https://www.grid.ac/institutes/grid.439641.d schema:alternateName Surrey and Sussex Healthcare NHS Trust
865 schema:name Department of Dermatology, Surrey and Sussex Healthcare NHS Trust, RH1 5RH, Surrey, UK
866 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...