The Cep57-pericentrin module organizes PCM expansion and centriole engagement View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Koki Watanabe, Daisuke Takao, Kei K Ito, Mikiko Takahashi, Daiju Kitagawa

ABSTRACT

Centriole duplication occurs once per cell cycle to ensure robust formation of bipolar spindles and chromosome segregation. Each newly-formed daughter centriole remains connected to its mother centriole until late mitosis. The disengagement of the centriole pair is required for centriole duplication. However, the mechanisms underlying centriole engagement remain poorly understood. Here, we show that Cep57 is required for pericentriolar material (PCM) organization that regulates centriole engagement. Depletion of Cep57 causes PCM disorganization and precocious centriole disengagement during mitosis. The disengaged daughter centrioles acquire ectopic microtubule-organizing-center activity, which results in chromosome mis-segregation. Similar defects are observed in mosaic variegated aneuploidy syndrome patient cells with cep57 mutations. We also find that Cep57 binds to the well-conserved PACT domain of pericentrin. Microcephaly osteodysplastic primordial dwarfism disease pericentrin mutations impair the Cep57-pericentrin interaction and lead to PCM disorganization. Together, our work demonstrates that Cep57 provides a critical interface between the centriole core and PCM. More... »

PAGES

931

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41467-019-08862-2

DOI

http://dx.doi.org/10.1038/s41467-019-08862-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112364087

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30804344


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Division of Centrosome Biology, National Institute of Genetics, 411-8540, Mishima, Shizuoka, Japan", 
            "Department of Genetics, School of Life Science, The Graduate University for Advanced Studies (SOKENDAI), 240-0193, Hayama, Kanagawa, Japan", 
            "Department of Physiological Chemistry, Graduate school of Pharmaceutical Sciences, The University of Tokyo, Bunkyo, 113-0033, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Watanabe", 
        "givenName": "Koki", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Division of Centrosome Biology, National Institute of Genetics, 411-8540, Mishima, Shizuoka, Japan", 
            "Department of Physiological Chemistry, Graduate school of Pharmaceutical Sciences, The University of Tokyo, Bunkyo, 113-0033, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Takao", 
        "givenName": "Daisuke", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Physiological Chemistry, Graduate school of Pharmaceutical Sciences, The University of Tokyo, Bunkyo, 113-0033, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ito", 
        "givenName": "Kei K", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Teikyo Heisei University", 
          "id": "https://www.grid.ac/institutes/grid.440938.2", 
          "name": [
            "Faculty of Pharmaceutical Sciences, Teikyo Heisei University, Nakano, 164-8530, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Takahashi", 
        "givenName": "Mikiko", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Division of Centrosome Biology, National Institute of Genetics, 411-8540, Mishima, Shizuoka, Japan", 
            "Department of Genetics, School of Life Science, The Graduate University for Advanced Studies (SOKENDAI), 240-0193, Hayama, Kanagawa, Japan", 
            "Department of Physiological Chemistry, Graduate school of Pharmaceutical Sciences, The University of Tokyo, Bunkyo, 113-0033, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kitagawa", 
        "givenName": "Daiju", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1042/bj20071501", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000965699"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj20071501", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000965699"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrm4062", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002965183", 
          "https://doi.org/10.1038/nrm4062"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cub.2010.08.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004110822"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1091/mbc.e13-10-0617", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005107484"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ceb.2005.12.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008115943"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0138905", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009981398"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ceb.2012.01.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011393791"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1091/mbc.e06-01-0039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013785843"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1091/mbc.e02-02-0112", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015002927"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncomms10076", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016561955", 
          "https://doi.org/10.1038/ncomms10076"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cub.2012.12.030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020338882"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/cr.2012.61", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022062426", 
          "https://doi.org/10.1038/cr.2012.61"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.devcel.2010.05.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023399297"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncb3076", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025933953", 
          "https://doi.org/10.1038/ncb3076"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncomms10151", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026695616", 
          "https://doi.org/10.1038/ncomms10151"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cub.2010.05.050", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027458555"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2009.10.036", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028810474"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ajmg.a.33984", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030009499"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cub.2012.03.048", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030986317"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4161/cc.20878", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033044595"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncb2345", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037549723", 
          "https://doi.org/10.1038/ncb2345"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/cshperspect.a015800", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038138666"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc3995", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039571581", 
          "https://doi.org/10.1038/nrc3995"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2007.07.023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040887330"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.822", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041522121", 
          "https://doi.org/10.1038/ng.822"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/embo-reports/kvd105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042854266"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.devcel.2009.07.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043026222"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.15252/embj.201488979", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047033633"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ajmg.a.36166", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047412462"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.201106093", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052630499"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1151174", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062457184"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-16-1144", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063216254"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.201701041", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1086044844"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev-cellbio-100616-060454", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091226587"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-12", 
    "datePublishedReg": "2019-12-01", 
    "description": "Centriole duplication occurs once per cell cycle to ensure robust formation of bipolar spindles and chromosome segregation. Each newly-formed daughter centriole remains connected to its mother centriole until late mitosis. The disengagement of the centriole pair is required for centriole duplication. However, the mechanisms underlying centriole engagement remain poorly understood. Here, we show that Cep57 is required for pericentriolar material (PCM) organization that regulates centriole engagement. Depletion of Cep57 causes PCM disorganization and precocious centriole disengagement during mitosis. The disengaged daughter centrioles acquire ectopic microtubule-organizing-center activity, which results in chromosome mis-segregation. Similar defects are observed in mosaic variegated aneuploidy syndrome patient cells with cep57 mutations. We also find that Cep57 binds to the well-conserved PACT domain of pericentrin. Microcephaly osteodysplastic primordial dwarfism disease pericentrin mutations impair the Cep57-pericentrin interaction and lead to PCM disorganization. Together, our work demonstrates that Cep57 provides a critical interface between the centriole core and PCM.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/s41467-019-08862-2", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1043282", 
        "issn": [
          "2041-1723"
        ], 
        "name": "Nature Communications", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "10"
      }
    ], 
    "name": "The Cep57-pericentrin module organizes PCM expansion and centriole engagement", 
    "pagination": "931", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "5d6850d89b2906c698dbae58ad1892acbe6c9c63333fc37d3138780f73ef078a"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30804344"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101528555"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s41467-019-08862-2"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1112364087"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s41467-019-08862-2", 
      "https://app.dimensions.ai/details/publication/pub.1112364087"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:53", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000364_0000000364/records_72853_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/s41467-019-08862-2"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41467-019-08862-2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41467-019-08862-2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41467-019-08862-2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41467-019-08862-2'


 

This table displays all metadata directly associated to this object as RDF triples.

206 TRIPLES      21 PREDICATES      63 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s41467-019-08862-2 schema:about anzsrc-for:06
2 anzsrc-for:0601
3 schema:author N246f99a0af6c4dbfa334551be20a5d63
4 schema:citation sg:pub.10.1038/cr.2012.61
5 sg:pub.10.1038/ncb2345
6 sg:pub.10.1038/ncb3076
7 sg:pub.10.1038/ncomms10076
8 sg:pub.10.1038/ncomms10151
9 sg:pub.10.1038/ng.822
10 sg:pub.10.1038/nrc3995
11 sg:pub.10.1038/nrm4062
12 https://doi.org/10.1002/ajmg.a.33984
13 https://doi.org/10.1002/ajmg.a.36166
14 https://doi.org/10.1016/j.ceb.2005.12.008
15 https://doi.org/10.1016/j.ceb.2012.01.003
16 https://doi.org/10.1016/j.cell.2007.07.023
17 https://doi.org/10.1016/j.cell.2009.10.036
18 https://doi.org/10.1016/j.cub.2010.05.050
19 https://doi.org/10.1016/j.cub.2010.08.010
20 https://doi.org/10.1016/j.cub.2012.03.048
21 https://doi.org/10.1016/j.cub.2012.12.030
22 https://doi.org/10.1016/j.devcel.2009.07.015
23 https://doi.org/10.1016/j.devcel.2010.05.017
24 https://doi.org/10.1042/bj20071501
25 https://doi.org/10.1083/jcb.201106093
26 https://doi.org/10.1083/jcb.201701041
27 https://doi.org/10.1091/mbc.e02-02-0112
28 https://doi.org/10.1091/mbc.e06-01-0039
29 https://doi.org/10.1091/mbc.e13-10-0617
30 https://doi.org/10.1093/embo-reports/kvd105
31 https://doi.org/10.1101/cshperspect.a015800
32 https://doi.org/10.1126/science.1151174
33 https://doi.org/10.1146/annurev-cellbio-100616-060454
34 https://doi.org/10.1158/0008-5472.can-16-1144
35 https://doi.org/10.1371/journal.pone.0138905
36 https://doi.org/10.15252/embj.201488979
37 https://doi.org/10.4161/cc.20878
38 schema:datePublished 2019-12
39 schema:datePublishedReg 2019-12-01
40 schema:description Centriole duplication occurs once per cell cycle to ensure robust formation of bipolar spindles and chromosome segregation. Each newly-formed daughter centriole remains connected to its mother centriole until late mitosis. The disengagement of the centriole pair is required for centriole duplication. However, the mechanisms underlying centriole engagement remain poorly understood. Here, we show that Cep57 is required for pericentriolar material (PCM) organization that regulates centriole engagement. Depletion of Cep57 causes PCM disorganization and precocious centriole disengagement during mitosis. The disengaged daughter centrioles acquire ectopic microtubule-organizing-center activity, which results in chromosome mis-segregation. Similar defects are observed in mosaic variegated aneuploidy syndrome patient cells with cep57 mutations. We also find that Cep57 binds to the well-conserved PACT domain of pericentrin. Microcephaly osteodysplastic primordial dwarfism disease pericentrin mutations impair the Cep57-pericentrin interaction and lead to PCM disorganization. Together, our work demonstrates that Cep57 provides a critical interface between the centriole core and PCM.
41 schema:genre research_article
42 schema:inLanguage en
43 schema:isAccessibleForFree true
44 schema:isPartOf N42f655d2c0634fefabc72987485d80c1
45 N5c8279ddf0c64fd5aec76d8a5190d46d
46 sg:journal.1043282
47 schema:name The Cep57-pericentrin module organizes PCM expansion and centriole engagement
48 schema:pagination 931
49 schema:productId N1267a883357a486eb33c55cfbeabd3a7
50 N43a3ad6f2cc94f6992d648ffcaadb7d0
51 N5baa3f97f6494c378be81695eb95b080
52 N7f8986aea718423a8a1d4689c27525ed
53 Nea696d3fa82a43c6ba98d7c004787141
54 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112364087
55 https://doi.org/10.1038/s41467-019-08862-2
56 schema:sdDatePublished 2019-04-11T12:53
57 schema:sdLicense https://scigraph.springernature.com/explorer/license/
58 schema:sdPublisher N6e27a0f5a3204fa9abb05bf1608fc67b
59 schema:url https://www.nature.com/articles/s41467-019-08862-2
60 sgo:license sg:explorer/license/
61 sgo:sdDataset articles
62 rdf:type schema:ScholarlyArticle
63 N111f7726f817436fb2aec890a4807abd schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
64 schema:familyName Kitagawa
65 schema:givenName Daiju
66 rdf:type schema:Person
67 N1267a883357a486eb33c55cfbeabd3a7 schema:name doi
68 schema:value 10.1038/s41467-019-08862-2
69 rdf:type schema:PropertyValue
70 N246f99a0af6c4dbfa334551be20a5d63 rdf:first Na15187516f6d4d6eb31163f62246daa1
71 rdf:rest Nbfa0c2762bd44689b4cb992566f587cd
72 N42f655d2c0634fefabc72987485d80c1 schema:issueNumber 1
73 rdf:type schema:PublicationIssue
74 N43a3ad6f2cc94f6992d648ffcaadb7d0 schema:name readcube_id
75 schema:value 5d6850d89b2906c698dbae58ad1892acbe6c9c63333fc37d3138780f73ef078a
76 rdf:type schema:PropertyValue
77 N4b05ea1e399d4033a063844d6414f3e5 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
78 schema:familyName Ito
79 schema:givenName Kei K
80 rdf:type schema:Person
81 N5baa3f97f6494c378be81695eb95b080 schema:name pubmed_id
82 schema:value 30804344
83 rdf:type schema:PropertyValue
84 N5bb352bfc638414fa0631184cb0014cf schema:affiliation https://www.grid.ac/institutes/grid.440938.2
85 schema:familyName Takahashi
86 schema:givenName Mikiko
87 rdf:type schema:Person
88 N5c8279ddf0c64fd5aec76d8a5190d46d schema:volumeNumber 10
89 rdf:type schema:PublicationVolume
90 N6b5c6cfa8c46434f85fd10e5faea962b schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
91 schema:familyName Takao
92 schema:givenName Daisuke
93 rdf:type schema:Person
94 N6e27a0f5a3204fa9abb05bf1608fc67b schema:name Springer Nature - SN SciGraph project
95 rdf:type schema:Organization
96 N7f8986aea718423a8a1d4689c27525ed schema:name nlm_unique_id
97 schema:value 101528555
98 rdf:type schema:PropertyValue
99 Na15187516f6d4d6eb31163f62246daa1 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
100 schema:familyName Watanabe
101 schema:givenName Koki
102 rdf:type schema:Person
103 Naaac59a7d7304061a1ab91121e476952 rdf:first N111f7726f817436fb2aec890a4807abd
104 rdf:rest rdf:nil
105 Nbfa0c2762bd44689b4cb992566f587cd rdf:first N6b5c6cfa8c46434f85fd10e5faea962b
106 rdf:rest Nf42019553315465f866128902316ed58
107 Ne206fc43cd8747a0afae3270c6cd3e27 rdf:first N5bb352bfc638414fa0631184cb0014cf
108 rdf:rest Naaac59a7d7304061a1ab91121e476952
109 Nea696d3fa82a43c6ba98d7c004787141 schema:name dimensions_id
110 schema:value pub.1112364087
111 rdf:type schema:PropertyValue
112 Nf42019553315465f866128902316ed58 rdf:first N4b05ea1e399d4033a063844d6414f3e5
113 rdf:rest Ne206fc43cd8747a0afae3270c6cd3e27
114 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
115 schema:name Biological Sciences
116 rdf:type schema:DefinedTerm
117 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
118 schema:name Biochemistry and Cell Biology
119 rdf:type schema:DefinedTerm
120 sg:journal.1043282 schema:issn 2041-1723
121 schema:name Nature Communications
122 rdf:type schema:Periodical
123 sg:pub.10.1038/cr.2012.61 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022062426
124 https://doi.org/10.1038/cr.2012.61
125 rdf:type schema:CreativeWork
126 sg:pub.10.1038/ncb2345 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037549723
127 https://doi.org/10.1038/ncb2345
128 rdf:type schema:CreativeWork
129 sg:pub.10.1038/ncb3076 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025933953
130 https://doi.org/10.1038/ncb3076
131 rdf:type schema:CreativeWork
132 sg:pub.10.1038/ncomms10076 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016561955
133 https://doi.org/10.1038/ncomms10076
134 rdf:type schema:CreativeWork
135 sg:pub.10.1038/ncomms10151 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026695616
136 https://doi.org/10.1038/ncomms10151
137 rdf:type schema:CreativeWork
138 sg:pub.10.1038/ng.822 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041522121
139 https://doi.org/10.1038/ng.822
140 rdf:type schema:CreativeWork
141 sg:pub.10.1038/nrc3995 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039571581
142 https://doi.org/10.1038/nrc3995
143 rdf:type schema:CreativeWork
144 sg:pub.10.1038/nrm4062 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002965183
145 https://doi.org/10.1038/nrm4062
146 rdf:type schema:CreativeWork
147 https://doi.org/10.1002/ajmg.a.33984 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030009499
148 rdf:type schema:CreativeWork
149 https://doi.org/10.1002/ajmg.a.36166 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047412462
150 rdf:type schema:CreativeWork
151 https://doi.org/10.1016/j.ceb.2005.12.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008115943
152 rdf:type schema:CreativeWork
153 https://doi.org/10.1016/j.ceb.2012.01.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011393791
154 rdf:type schema:CreativeWork
155 https://doi.org/10.1016/j.cell.2007.07.023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040887330
156 rdf:type schema:CreativeWork
157 https://doi.org/10.1016/j.cell.2009.10.036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028810474
158 rdf:type schema:CreativeWork
159 https://doi.org/10.1016/j.cub.2010.05.050 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027458555
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1016/j.cub.2010.08.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004110822
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1016/j.cub.2012.03.048 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030986317
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1016/j.cub.2012.12.030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020338882
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1016/j.devcel.2009.07.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043026222
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1016/j.devcel.2010.05.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023399297
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1042/bj20071501 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000965699
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1083/jcb.201106093 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052630499
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1083/jcb.201701041 schema:sameAs https://app.dimensions.ai/details/publication/pub.1086044844
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1091/mbc.e02-02-0112 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015002927
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1091/mbc.e06-01-0039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013785843
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1091/mbc.e13-10-0617 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005107484
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1093/embo-reports/kvd105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042854266
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1101/cshperspect.a015800 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038138666
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1126/science.1151174 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062457184
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1146/annurev-cellbio-100616-060454 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091226587
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1158/0008-5472.can-16-1144 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063216254
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1371/journal.pone.0138905 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009981398
194 rdf:type schema:CreativeWork
195 https://doi.org/10.15252/embj.201488979 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047033633
196 rdf:type schema:CreativeWork
197 https://doi.org/10.4161/cc.20878 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033044595
198 rdf:type schema:CreativeWork
199 https://www.grid.ac/institutes/grid.26999.3d schema:alternateName University of Tokyo
200 schema:name Department of Genetics, School of Life Science, The Graduate University for Advanced Studies (SOKENDAI), 240-0193, Hayama, Kanagawa, Japan
201 Department of Physiological Chemistry, Graduate school of Pharmaceutical Sciences, The University of Tokyo, Bunkyo, 113-0033, Tokyo, Japan
202 Division of Centrosome Biology, National Institute of Genetics, 411-8540, Mishima, Shizuoka, Japan
203 rdf:type schema:Organization
204 https://www.grid.ac/institutes/grid.440938.2 schema:alternateName Teikyo Heisei University
205 schema:name Faculty of Pharmaceutical Sciences, Teikyo Heisei University, Nakano, 164-8530, Tokyo, Japan
206 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...