Gut microbiota associations with common diseases and prescription medications in a population-based cohort View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-12

AUTHORS

Matthew A. Jackson, Serena Verdi, Maria-Emanuela Maxan, Cheol Min Shin, Jonas Zierer, Ruth C. E. Bowyer, Tiphaine Martin, Frances M. K. Williams, Cristina Menni, Jordana T. Bell, Tim D. Spector, Claire J. Steves

ABSTRACT

The human gut microbiome has been associated with many health factors but variability between studies limits exploration of effects between them. Gut microbiota profiles are available for >2700 members of the deeply phenotyped TwinsUK cohort, providing a uniform platform for such comparisons. Here, we present gut microbiota association analyses for 38 common diseases and 51 medications within the cohort. We describe several novel associations, highlight associations common across multiple diseases, and determine which diseases and medications have the greatest association with the gut microbiota. These results provide a reference for future studies of the gut microbiome and its role in human health. More... »

PAGES

2655

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41467-018-05184-7

DOI

http://dx.doi.org/10.1038/s41467-018-05184-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1105348577

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29985401


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