Ontology type: schema:ScholarlyArticle Open Access: True
2018-12
AUTHORSShantisree Sandeepani Rayagiri, Daniele Ranaldi, Alexander Raven, Nur Izzah Farhana Mohamad Azhar, Olivier Lefebvre, Peter S Zammit, Anne-Gaëlle Borycki
ABSTRACTA central question in stem cell biology is the relationship between stem cells and their niche. Although previous reports have uncovered how signaling molecules released by niche cells support stem cell function, the role of the extra-cellular matrix (ECM) within the niche is unclear. Here, we show that upon activation, skeletal muscle stem cells (satellite cells) induce local remodeling of the ECM and the deposition of laminin-α1 and laminin-α5 into the basal lamina of the satellite cell niche. Genetic ablation of laminin-α1, disruption of integrin-α6 signaling or blocking matrix metalloproteinase activity impairs satellite cell expansion and self-renewal. Collectively, our findings establish that remodeling of the ECM is an integral process of stem cell activity to support propagation and self-renewal, and may explain the effect laminin-α1-containing supports have on embryonic and adult stem cells, as well as the regenerative activity of exogenous laminin-111 therapy. More... »
PAGES1075
http://scigraph.springernature.com/pub.10.1038/s41467-018-03425-3
DOIhttp://dx.doi.org/10.1038/s41467-018-03425-3
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1101481569
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/29540680
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biochemistry and Cell Biology",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biological Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Animals",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Basement Membrane",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cell Differentiation",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cell Self Renewal",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Extracellular Matrix",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Mice, Inbred C57BL",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Muscle Fibers, Skeletal",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Muscle, Skeletal",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Satellite Cells, Skeletal Muscle",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Signal Transduction",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Stem Cell Niche",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Cancer Research UK",
"id": "https://www.grid.ac/institutes/grid.11485.39",
"name": [
"Department of Biomedical Science, University of Sheffield, Firth Court, S10 2TN, Western Bank, Sheffield, UK",
"Biotherapeutics Development Unit, Cancer Research UK, Clare Hall laboratories, Blanche Lane, South Mimms, EN6 3LD, Hertfordshire, UK"
],
"type": "Organization"
},
"familyName": "Rayagiri",
"givenName": "Shantisree Sandeepani",
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Sheffield",
"id": "https://www.grid.ac/institutes/grid.11835.3e",
"name": [
"Department of Biomedical Science, University of Sheffield, Firth Court, S10 2TN, Western Bank, Sheffield, UK"
],
"type": "Organization"
},
"familyName": "Ranaldi",
"givenName": "Daniele",
"type": "Person"
},
{
"affiliation": {
"alternateName": "MRC Centre for Regenerative Medicine",
"id": "https://www.grid.ac/institutes/grid.483689.8",
"name": [
"Department of Biomedical Science, University of Sheffield, Firth Court, S10 2TN, Western Bank, Sheffield, UK",
"MRC Centre for Regenerative Medicine, SCRM Building, University of Edinburgh, 5 Little France Drive, EH16 4UU, Edinburgh, UK"
],
"type": "Organization"
},
"familyName": "Raven",
"givenName": "Alexander",
"id": "sg:person.010516361714.37",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010516361714.37"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Sheffield",
"id": "https://www.grid.ac/institutes/grid.11835.3e",
"name": [
"Department of Biomedical Science, University of Sheffield, Firth Court, S10 2TN, Western Bank, Sheffield, UK",
"Oxford Publishing (Malaysia), 40150, Shah Alam, Selangor Darul Ehsan, Malaysia"
],
"type": "Organization"
},
"familyName": "Azhar",
"givenName": "Nur Izzah Farhana Mohamad",
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Strasbourg",
"id": "https://www.grid.ac/institutes/grid.11843.3f",
"name": [
"Inserm U1109 MN3T, F-67200, Strasbourg, France",
"Universit\u00e9 de Strasbourg, F-67000, Strasbourg, France",
"LabEx Medalis Universit\u00e9 de Strasbourg, F-67000, Strasbourg, France",
"F\u00e9d\u00e9ration de M\u00e9decine Translationnelle de Strasbourg (FMTS), F-67000, Strasbourg, France"
],
"type": "Organization"
},
"familyName": "Lefebvre",
"givenName": "Olivier",
"id": "sg:person.01074561304.90",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01074561304.90"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Randall Centre for Cell and Molecular Biophysics, Faculty of Life Sciences & Medicine King\u2019s College London, New Hunt\u2019s House, Guy\u2019s Campus, SE1 1UL, London, UK"
],
"type": "Organization"
},
"familyName": "Zammit",
"givenName": "Peter S",
"id": "sg:person.01362155670.99",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362155670.99"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Sheffield",
"id": "https://www.grid.ac/institutes/grid.11835.3e",
"name": [
"Department of Biomedical Science, University of Sheffield, Firth Court, S10 2TN, Western Bank, Sheffield, UK"
],
"type": "Organization"
},
"familyName": "Borycki",
"givenName": "Anne-Ga\u00eblle",
"id": "sg:person.01370524636.03",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01370524636.03"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1111/febs.12166",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000230019"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.bbadis.2015.07.008",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000453406"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1242/dev.068858",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000913750"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0163-7258(97)00023-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000943757"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nm.3465",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002058788",
"https://doi.org/10.1038/nm.3465"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1083/jcb.153.5.933",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002811572"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0925-4773(02)00292-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002900362"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0092-8674(00)00066-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003948568"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/(sici)1097-0177(200006)218:2<213::aid-dvdy1>3.0.co;2-r",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004903426"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/(sici)1097-0177(200006)218:2<213::aid-dvdy1>3.0.co;2-r",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004903426"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1242/dev.036087",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005667774"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.cell.2007.03.044",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006649264"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2353/ajpath.2009.080522",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006907574"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1006/dbio.1997.8668",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007088268"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.matbio.2005.12.001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009285969"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1083/jcb.9.2.493",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010893613"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1083/jcb.200710141",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012665014"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/path.3020",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012820175"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1242/dev.067587",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013959802"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/jnr.20778",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014169375"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/jnr.20778",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014169375"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature10834",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014259939",
"https://doi.org/10.1038/nature10834"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1371/journal.pone.0034219",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015891463"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.stem.2012.05.025",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016516222"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/mus.21616",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017465093"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/mus.21616",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017465093"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1074/jbc.m109.069575",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017895228"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/hmg/ddr362",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018051512"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nbt.1620",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019661466",
"https://doi.org/10.1038/nbt.1620"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nbt.1620",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019661466",
"https://doi.org/10.1038/nbt.1620"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ncomms2964",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020807443",
"https://doi.org/10.1038/ncomms2964"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/35102160",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021584545",
"https://doi.org/10.1038/35102160"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/35102160",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021584545",
"https://doi.org/10.1038/35102160"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.cell.2011.11.049",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021948593"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.cell.2011.11.049",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021948593"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/stem.1088",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022196557"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/978-1-4939-1435-7_6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024493395",
"https://doi.org/10.1007/978-1-4939-1435-7_6"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1083/jcb.139.6.1507",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026986560"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1242/dev.064162",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027006938"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.4161/cam.21831",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027263566"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1006/meth.2001.1262",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027621591"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1006/meth.2001.1262",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027621591"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.nbd.2012.07.023",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028264930"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/gene.20154",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028278272"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/gene.20154",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028278272"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/hmg/ddt428",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028538936"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.stem.2012.09.015",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035895195"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/dvdy.21259",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036204206"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1242/dev.067595",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036495502"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1083/jcb.200508044",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036677889"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.bmc.2004.01.047",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036694206"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0960-8966(99)00033-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037382101"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1242/dev.02336",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039624947"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/mus.10529",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041151502"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nm.3990",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042803553",
"https://doi.org/10.1038/nm.3990"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/stem.1197",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043835975"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/hmg/ddr062",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045332649"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.stemcr.2013.08.006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045340032"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.matbio.2006.03.004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046300865"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.stem.2007.12.012",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049924380"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1038/embor.2013.182",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050287455"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1242/dev.114223",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050343514"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0014-4827(92)90357-e",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050777329"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1006/excr.2000.4842",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052460115"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1089/ten.teb.2008.0045",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1059316900"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.4161/cam.23411",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1072291817"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082377481",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082925237",
"type": "CreativeWork"
}
],
"datePublished": "2018-12",
"datePublishedReg": "2018-12-01",
"description": "A central question in stem cell biology is the relationship between stem cells and their niche. Although previous reports have uncovered how signaling molecules released by niche cells support stem cell function, the role of the extra-cellular matrix (ECM) within the niche is unclear. Here, we show that upon activation, skeletal muscle stem cells (satellite cells) induce local remodeling of the ECM and the deposition of laminin-\u03b11 and laminin-\u03b15 into the basal lamina of the satellite cell niche. Genetic ablation of laminin-\u03b11, disruption of integrin-\u03b16 signaling or blocking matrix metalloproteinase activity impairs satellite cell expansion and self-renewal. Collectively, our findings establish that remodeling of the ECM is an integral process of stem cell activity to support propagation and self-renewal, and may explain the effect laminin-\u03b11-containing supports have on embryonic and adult stem cells, as well as the regenerative activity of exogenous laminin-111 therapy.",
"genre": "research_article",
"id": "sg:pub.10.1038/s41467-018-03425-3",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1043282",
"issn": [
"2041-1723"
],
"name": "Nature Communications",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "9"
}
],
"name": "Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal",
"pagination": "1075",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"2b3889bb583e1ab3a197e33432a2e2332789fe3315d844599c447f4ec8c37ee3"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"29540680"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"101528555"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/s41467-018-03425-3"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1101481569"
]
}
],
"sameAs": [
"https://doi.org/10.1038/s41467-018-03425-3",
"https://app.dimensions.ai/details/publication/pub.1101481569"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T11:48",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000358_0000000358/records_127463_00000010.jsonl",
"type": "ScholarlyArticle",
"url": "https://www.nature.com/articles/s41467-018-03425-3"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41467-018-03425-3'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41467-018-03425-3'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41467-018-03425-3'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41467-018-03425-3'
This table displays all metadata directly associated to this object as RDF triples.
357 TRIPLES
21 PREDICATES
101 URIs
33 LITERALS
21 BLANK NODES