A-to-I miR-378a-3p editing can prevent melanoma progression via regulation of PARVA expression View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-12

AUTHORS

Guermarie Velazquez-Torres, Einav Shoshan, Cristina Ivan, Li Huang, Enrique Fuentes-Mattei, Harrison Paret, Sun Jin Kim, Cristian Rodriguez-Aguayo, Victoria Xie, Denise Brooks, Steven J. M. Jones, A. Gordon Robertson, George Calin, Gabriel Lopez-Berenstein, Anil Sood, Menashe Bar-Eli

ABSTRACT

Previously we have reported that metastatic melanoma cell lines and tumor specimens have reduced expression of ADAR1 and consequently are impaired in their ability to perform A-to-I microRNA (miRNA) editing. The effects of A-to-I miRNAs editing on melanoma growth and metastasis are yet to be determined. Here we report that miR-378a-3p is undergoing A-to-I editing only in the non-metastatic but not in metastatic melanoma cells. The function of the edited form is different from its wild-type counterpart. The edited form of miR-378a-3p preferentially binds to the 3'-UTR of the PARVA oncogene and inhibits its expression, thus preventing the progression of melanoma towards the malignant phenotype. Indeed, edited miR-378a-3p but not its WT form inhibits melanoma metastasis in vivo. These results further emphasize the role of RNA editing in melanoma progression. More... »

PAGES

461

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41467-018-02851-7

DOI

http://dx.doi.org/10.1038/s41467-018-02851-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1100657961

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29386624


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "3' Untranslated Regions", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adenosine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Line, Tumor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Proliferation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease Progression", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Epigenesis, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Regulation, Neoplastic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Inosine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Melanoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Nude", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "MicroRNAs", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microfilament Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Invasiveness", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Metastasis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oncogenes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA Editing", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Skin Neoplasms", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Cancer Biology, Unit 1906, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, 77030, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Velazquez-Torres", 
        "givenName": "Guermarie", 
        "id": "sg:person.01021027001.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021027001.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Cancer Biology, Unit 1906, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, 77030, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shoshan", 
        "givenName": "Einav", 
        "id": "sg:person.01344724200.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01344724200.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Gynecologic Oncology, Unit 1362, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ivan", 
        "givenName": "Cristina", 
        "id": "sg:person.01354560625.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354560625.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Cancer Biology, Unit 1906, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, 77030, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Huang", 
        "givenName": "Li", 
        "id": "sg:person.012350726577.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012350726577.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Experimental Therapeutics, Unit 1950, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, 77030, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fuentes-Mattei", 
        "givenName": "Enrique", 
        "id": "sg:person.01317617201.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317617201.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Cancer Biology, Unit 1906, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, 77030, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Paret", 
        "givenName": "Harrison", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Cancer Biology, Unit 1906, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, 77030, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kim", 
        "givenName": "Sun Jin", 
        "id": "sg:person.014375355307.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014375355307.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Experimental Therapeutics, Unit 1950, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, 77030, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rodriguez-Aguayo", 
        "givenName": "Cristian", 
        "id": "sg:person.01257563174.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257563174.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Xie", 
        "givenName": "Victoria", 
        "id": "sg:person.01342026204.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342026204.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Canada\u2019s Michael Smith Cancer Agency, V5Z4S6, Vancouver, BC, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Brooks", 
        "givenName": "Denise", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Canada\u2019s Michael Smith Cancer Agency, V5Z4S6, Vancouver, BC, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jones", 
        "givenName": "Steven J. M.", 
        "id": "sg:person.011076371162.80", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011076371162.80"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Canada\u2019s Michael Smith Cancer Agency, V5Z4S6, Vancouver, BC, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Robertson", 
        "givenName": "A. Gordon", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Experimental Therapeutics, Unit 1950, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, 77030, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Calin", 
        "givenName": "George", 
        "id": "sg:person.01176437025.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01176437025.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Experimental Therapeutics, Unit 1950, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, 77030, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lopez-Berenstein", 
        "givenName": "Gabriel", 
        "id": "sg:person.01115051510.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115051510.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Gynecologic Oncology, Unit 1362, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sood", 
        "givenName": "Anil", 
        "id": "sg:person.01074353043.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01074353043.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas MD Anderson Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.240145.6", 
          "name": [
            "Department of Cancer Biology, Unit 1906, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, 77030, Houston, TX, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bar-Eli", 
        "givenName": "Menashe", 
        "id": "sg:person.01160523062.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01160523062.28"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1371/journal.pone.0118530", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002130722"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0118530", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002130722"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m508683200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005252934"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m508683200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005252934"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m109.019836", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014490168"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3322/caac.21387", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014894112"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncomms10993", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017154708", 
          "https://doi.org/10.1038/ncomms10993"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13277-015-4710-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018249828", 
          "https://doi.org/10.1007/s13277-015-4710-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13277-015-3996-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018800013", 
          "https://doi.org/10.1007/s13277-015-3996-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m112.385229", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026359223"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-05-0530", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030443527"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci62980", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031724930"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0012452", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032875127"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/07357907.2015.1047508", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035954777"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrm1789", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036759909", 
          "https://doi.org/10.1038/nrm1789"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrm1789", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036759909", 
          "https://doi.org/10.1038/nrm1789"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncb3110", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037204646", 
          "https://doi.org/10.1038/ncb3110"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1201358", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037217388", 
          "https://doi.org/10.1038/sj.onc.1201358"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1201358", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037217388", 
          "https://doi.org/10.1038/sj.onc.1201358"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10549-014-2859-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037631377", 
          "https://doi.org/10.1007/s10549-014-2859-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.3694", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042300353", 
          "https://doi.org/10.1038/ng.3694"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.273.38.24884", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043567766"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00018-005-5355-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045832152", 
          "https://doi.org/10.1007/s00018-005-5355-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00018-005-5355-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045832152", 
          "https://doi.org/10.1007/s00018-005-5355-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.142.3.827", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047165335"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep19455", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049246797", 
          "https://doi.org/10.1038/srep19455"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep19455", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049246797", 
          "https://doi.org/10.1038/srep19455"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.26396", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050860270"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4161/cbt.7.7.6535", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072295035"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077605660", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079131351", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-12", 
    "datePublishedReg": "2018-12-01", 
    "description": "Previously we have reported that metastatic melanoma cell lines and tumor specimens have reduced expression of ADAR1 and consequently are impaired in their ability to perform A-to-I microRNA (miRNA) editing. The effects of A-to-I miRNAs editing on melanoma growth and metastasis are yet to be determined. Here we report that miR-378a-3p is undergoing A-to-I editing only in the non-metastatic but not in metastatic melanoma cells. The function of the edited form is different from its wild-type counterpart. The edited form of miR-378a-3p preferentially binds to the 3'-UTR of the PARVA oncogene and inhibits its expression, thus preventing the progression of melanoma towards the malignant phenotype. Indeed, edited miR-378a-3p but not its WT form inhibits melanoma metastasis in vivo. These results further emphasize the role of RNA editing in melanoma progression.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/s41467-018-02851-7", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2440238", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.3624488", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2440176", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.4243123", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2438826", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1043282", 
        "issn": [
          "2041-1723"
        ], 
        "name": "Nature Communications", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "9"
      }
    ], 
    "name": "A-to-I miR-378a-3p editing can prevent melanoma progression via regulation of PARVA expression", 
    "pagination": "461", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "58cae2cf48abcb824dc065d89f368320f3af62a6d0538c2aae73bfd04d4f0342"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "29386624"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101528555"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s41467-018-02851-7"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1100657961"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s41467-018-02851-7", 
      "https://app.dimensions.ai/details/publication/pub.1100657961"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T20:53", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8684_00000552.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/s41467-018-02851-7"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41467-018-02851-7'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41467-018-02851-7'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41467-018-02851-7'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41467-018-02851-7'


 

This table displays all metadata directly associated to this object as RDF triples.

356 TRIPLES      21 PREDICATES      75 URIs      42 LITERALS      30 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s41467-018-02851-7 schema:about N0820bf3097a64a76a363f0c6fa474f43
2 N0fc52da45939436e8d8837952244e9ce
3 N189570d927814544a342682d2ff145f8
4 N1f9e5e819ce342fc8de5c47e6d53dc22
5 N2603ccd619274ff9af54aff4692d6e63
6 N2e14105468474e25a10c500211c9e7f0
7 N3c782249dc914191a4f6a4a42917ae01
8 N47aaaec020af49538ac22bd767f7db33
9 N64cb4e254aa6424ca9d4a2075e5c6053
10 N8976b1453d2b4f1ca70663d5ea28c2d2
11 N9357ed5d4f53471298ae36aae98713ed
12 N9896a082e9a1422485548b6ebbceb969
13 Na4689d88f1f24e9ea008cf8cfcf7d13c
14 Na6ae242839df4031a948a82a48045fd2
15 Nabf06734e90340ceb9a7ba8b366b8766
16 Nd04b4c9894e34bce8b5ef69d96feaf31
17 Nd6f0c56ef6eb4f7f832910db0084db94
18 Nd722e3e0c4584ed8824ec05705ab589c
19 Nd7c7698cabf445bb8232819595b79873
20 Ne6bdcaed821b408bbb6ea791aecad8cb
21 Ne8d2646962e54bb68ab43627af70e48e
22 anzsrc-for:11
23 anzsrc-for:1112
24 schema:author Ne4c2d8ab2a1d413a9aa69f925c504e22
25 schema:citation sg:pub.10.1007/s00018-005-5355-1
26 sg:pub.10.1007/s10549-014-2859-0
27 sg:pub.10.1007/s13277-015-3996-8
28 sg:pub.10.1007/s13277-015-4710-6
29 sg:pub.10.1038/ncb3110
30 sg:pub.10.1038/ncomms10993
31 sg:pub.10.1038/ng.3694
32 sg:pub.10.1038/nrm1789
33 sg:pub.10.1038/sj.onc.1201358
34 sg:pub.10.1038/srep19455
35 https://app.dimensions.ai/details/publication/pub.1077605660
36 https://app.dimensions.ai/details/publication/pub.1079131351
37 https://doi.org/10.1002/hep.26396
38 https://doi.org/10.1074/jbc.273.38.24884
39 https://doi.org/10.1074/jbc.m109.019836
40 https://doi.org/10.1074/jbc.m112.385229
41 https://doi.org/10.1074/jbc.m508683200
42 https://doi.org/10.1083/jcb.142.3.827
43 https://doi.org/10.1158/0008-5472.can-05-0530
44 https://doi.org/10.1172/jci62980
45 https://doi.org/10.1371/journal.pone.0012452
46 https://doi.org/10.1371/journal.pone.0118530
47 https://doi.org/10.3109/07357907.2015.1047508
48 https://doi.org/10.3322/caac.21387
49 https://doi.org/10.4161/cbt.7.7.6535
50 schema:datePublished 2018-12
51 schema:datePublishedReg 2018-12-01
52 schema:description Previously we have reported that metastatic melanoma cell lines and tumor specimens have reduced expression of ADAR1 and consequently are impaired in their ability to perform A-to-I microRNA (miRNA) editing. The effects of A-to-I miRNAs editing on melanoma growth and metastasis are yet to be determined. Here we report that miR-378a-3p is undergoing A-to-I editing only in the non-metastatic but not in metastatic melanoma cells. The function of the edited form is different from its wild-type counterpart. The edited form of miR-378a-3p preferentially binds to the 3'-UTR of the PARVA oncogene and inhibits its expression, thus preventing the progression of melanoma towards the malignant phenotype. Indeed, edited miR-378a-3p but not its WT form inhibits melanoma metastasis in vivo. These results further emphasize the role of RNA editing in melanoma progression.
53 schema:genre research_article
54 schema:inLanguage en
55 schema:isAccessibleForFree true
56 schema:isPartOf N584a1dbad216494bb3ce97327a7e0f97
57 Ncc0a22888aa24aeeb8a8c476c3f2d9b6
58 sg:journal.1043282
59 schema:name A-to-I miR-378a-3p editing can prevent melanoma progression via regulation of PARVA expression
60 schema:pagination 461
61 schema:productId N59fb98471d3942d5b92c91989c5be8cb
62 N69358e9ac1d14c5290db34af20dd63f9
63 Nc19c6d6b645c4f09b77ccd2f39c94812
64 Ne33f8452a9ac4bada0b57533d4e2d199
65 Nf1565dff8555428992cb9dee716952ec
66 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100657961
67 https://doi.org/10.1038/s41467-018-02851-7
68 schema:sdDatePublished 2019-04-10T20:53
69 schema:sdLicense https://scigraph.springernature.com/explorer/license/
70 schema:sdPublisher N141595ba0a91400bbf0e68924780fd95
71 schema:url https://www.nature.com/articles/s41467-018-02851-7
72 sgo:license sg:explorer/license/
73 sgo:sdDataset articles
74 rdf:type schema:ScholarlyArticle
75 N0820bf3097a64a76a363f0c6fa474f43 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Cell Proliferation
77 rdf:type schema:DefinedTerm
78 N0a8f275deca64e21aee146ef5e3e2768 schema:affiliation N78143a01f72c467ea6d8d1670f503501
79 schema:familyName Brooks
80 schema:givenName Denise
81 rdf:type schema:Person
82 N0d65f5a8f73e4c87a704f38347c0846f schema:affiliation https://www.grid.ac/institutes/grid.240145.6
83 schema:familyName Paret
84 schema:givenName Harrison
85 rdf:type schema:Person
86 N0fc52da45939436e8d8837952244e9ce schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Mice, Nude
88 rdf:type schema:DefinedTerm
89 N141595ba0a91400bbf0e68924780fd95 schema:name Springer Nature - SN SciGraph project
90 rdf:type schema:Organization
91 N189570d927814544a342682d2ff145f8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Melanoma
93 rdf:type schema:DefinedTerm
94 N1b45d0cd1d1f48b4929256d4e1a0cdc7 rdf:first sg:person.01344724200.05
95 rdf:rest N64f58d843f9d4dcfa5f844ef9dadae4a
96 N1f9e5e819ce342fc8de5c47e6d53dc22 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Gene Expression Regulation, Neoplastic
98 rdf:type schema:DefinedTerm
99 N2603ccd619274ff9af54aff4692d6e63 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name RNA Editing
101 rdf:type schema:DefinedTerm
102 N2e14105468474e25a10c500211c9e7f0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Humans
104 rdf:type schema:DefinedTerm
105 N2e4e0f3d49224cecb907376a82db6f46 rdf:first sg:person.01115051510.99
106 rdf:rest N4e96980ab5a14106bae9a52f2f840a61
107 N3c782249dc914191a4f6a4a42917ae01 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Inosine
109 rdf:type schema:DefinedTerm
110 N40a8f3f47c574d37a180710ec9c12602 rdf:first sg:person.012350726577.33
111 rdf:rest N73e6a35b87724464825bd01b8dd93317
112 N47aaaec020af49538ac22bd767f7db33 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Disease Progression
114 rdf:type schema:DefinedTerm
115 N4e96980ab5a14106bae9a52f2f840a61 rdf:first sg:person.01074353043.17
116 rdf:rest N5e447a49a77f4bf7893f10e7dc611eda
117 N584a1dbad216494bb3ce97327a7e0f97 schema:issueNumber 1
118 rdf:type schema:PublicationIssue
119 N59fb98471d3942d5b92c91989c5be8cb schema:name doi
120 schema:value 10.1038/s41467-018-02851-7
121 rdf:type schema:PropertyValue
122 N5e447a49a77f4bf7893f10e7dc611eda rdf:first sg:person.01160523062.28
123 rdf:rest rdf:nil
124 N62d1f8f7a9154628b77bed615b962503 rdf:first sg:person.01176437025.21
125 rdf:rest N2e4e0f3d49224cecb907376a82db6f46
126 N64cb4e254aa6424ca9d4a2075e5c6053 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Neoplasm Invasiveness
128 rdf:type schema:DefinedTerm
129 N64f58d843f9d4dcfa5f844ef9dadae4a rdf:first sg:person.01354560625.68
130 rdf:rest N40a8f3f47c574d37a180710ec9c12602
131 N69358e9ac1d14c5290db34af20dd63f9 schema:name readcube_id
132 schema:value 58cae2cf48abcb824dc065d89f368320f3af62a6d0538c2aae73bfd04d4f0342
133 rdf:type schema:PropertyValue
134 N71bf00e0e6bf4f88a31f2124ee4cdafd schema:name Canada’s Michael Smith Cancer Agency, V5Z4S6, Vancouver, BC, Canada
135 rdf:type schema:Organization
136 N73e6a35b87724464825bd01b8dd93317 rdf:first sg:person.01317617201.88
137 rdf:rest Ne55d09ee22fc4e0c9bc6e46e23833d33
138 N78143a01f72c467ea6d8d1670f503501 schema:name Canada’s Michael Smith Cancer Agency, V5Z4S6, Vancouver, BC, Canada
139 rdf:type schema:Organization
140 N8976b1453d2b4f1ca70663d5ea28c2d2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Animals
142 rdf:type schema:DefinedTerm
143 N8be2aa428c8a4bc79c4f2a02fd89a638 schema:name Canada’s Michael Smith Cancer Agency, V5Z4S6, Vancouver, BC, Canada
144 rdf:type schema:Organization
145 N8e2a15df89f943629b49486adbd39c1f rdf:first Nf946ccb884bf48728b8f5357d10ee898
146 rdf:rest N62d1f8f7a9154628b77bed615b962503
147 N9357ed5d4f53471298ae36aae98713ed schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Epigenesis, Genetic
149 rdf:type schema:DefinedTerm
150 N9896a082e9a1422485548b6ebbceb969 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name 3' Untranslated Regions
152 rdf:type schema:DefinedTerm
153 Na4689d88f1f24e9ea008cf8cfcf7d13c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Microfilament Proteins
155 rdf:type schema:DefinedTerm
156 Na6ae242839df4031a948a82a48045fd2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name MicroRNAs
158 rdf:type schema:DefinedTerm
159 Nabf06734e90340ceb9a7ba8b366b8766 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Skin Neoplasms
161 rdf:type schema:DefinedTerm
162 Naf9236fc9e14413eb986114f69767bfd rdf:first sg:person.01257563174.54
163 rdf:rest Nd50c0b0205394f108eb62480c6c7b862
164 Nc19c6d6b645c4f09b77ccd2f39c94812 schema:name dimensions_id
165 schema:value pub.1100657961
166 rdf:type schema:PropertyValue
167 Ncc0a22888aa24aeeb8a8c476c3f2d9b6 schema:volumeNumber 9
168 rdf:type schema:PublicationVolume
169 Nd04b4c9894e34bce8b5ef69d96feaf31 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Female
171 rdf:type schema:DefinedTerm
172 Nd50c0b0205394f108eb62480c6c7b862 rdf:first sg:person.01342026204.71
173 rdf:rest Nedc7e3bf32d844428fab48dcb1421ad2
174 Nd6f0c56ef6eb4f7f832910db0084db94 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
175 schema:name Mice
176 rdf:type schema:DefinedTerm
177 Nd722e3e0c4584ed8824ec05705ab589c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Adenosine
179 rdf:type schema:DefinedTerm
180 Nd7c7698cabf445bb8232819595b79873 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
181 schema:name Cell Line, Tumor
182 rdf:type schema:DefinedTerm
183 Ndc3d8908233344d99ce7e40bfb17165c rdf:first sg:person.011076371162.80
184 rdf:rest N8e2a15df89f943629b49486adbd39c1f
185 Ne33f8452a9ac4bada0b57533d4e2d199 schema:name nlm_unique_id
186 schema:value 101528555
187 rdf:type schema:PropertyValue
188 Ne4c2d8ab2a1d413a9aa69f925c504e22 rdf:first sg:person.01021027001.42
189 rdf:rest N1b45d0cd1d1f48b4929256d4e1a0cdc7
190 Ne55d09ee22fc4e0c9bc6e46e23833d33 rdf:first N0d65f5a8f73e4c87a704f38347c0846f
191 rdf:rest Nff8d86d979644b19831a2105981e6557
192 Ne6bdcaed821b408bbb6ea791aecad8cb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
193 schema:name Neoplasm Metastasis
194 rdf:type schema:DefinedTerm
195 Ne8d2646962e54bb68ab43627af70e48e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
196 schema:name Oncogenes
197 rdf:type schema:DefinedTerm
198 Nedc7e3bf32d844428fab48dcb1421ad2 rdf:first N0a8f275deca64e21aee146ef5e3e2768
199 rdf:rest Ndc3d8908233344d99ce7e40bfb17165c
200 Nf1565dff8555428992cb9dee716952ec schema:name pubmed_id
201 schema:value 29386624
202 rdf:type schema:PropertyValue
203 Nf946ccb884bf48728b8f5357d10ee898 schema:affiliation N71bf00e0e6bf4f88a31f2124ee4cdafd
204 schema:familyName Robertson
205 schema:givenName A. Gordon
206 rdf:type schema:Person
207 Nff8d86d979644b19831a2105981e6557 rdf:first sg:person.014375355307.61
208 rdf:rest Naf9236fc9e14413eb986114f69767bfd
209 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
210 schema:name Medical and Health Sciences
211 rdf:type schema:DefinedTerm
212 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
213 schema:name Oncology and Carcinogenesis
214 rdf:type schema:DefinedTerm
215 sg:grant.2438826 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-018-02851-7
216 rdf:type schema:MonetaryGrant
217 sg:grant.2440176 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-018-02851-7
218 rdf:type schema:MonetaryGrant
219 sg:grant.2440238 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-018-02851-7
220 rdf:type schema:MonetaryGrant
221 sg:grant.3624488 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-018-02851-7
222 rdf:type schema:MonetaryGrant
223 sg:grant.4243123 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-018-02851-7
224 rdf:type schema:MonetaryGrant
225 sg:journal.1043282 schema:issn 2041-1723
226 schema:name Nature Communications
227 rdf:type schema:Periodical
228 sg:person.01021027001.42 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
229 schema:familyName Velazquez-Torres
230 schema:givenName Guermarie
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021027001.42
232 rdf:type schema:Person
233 sg:person.01074353043.17 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
234 schema:familyName Sood
235 schema:givenName Anil
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01074353043.17
237 rdf:type schema:Person
238 sg:person.011076371162.80 schema:affiliation N8be2aa428c8a4bc79c4f2a02fd89a638
239 schema:familyName Jones
240 schema:givenName Steven J. M.
241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011076371162.80
242 rdf:type schema:Person
243 sg:person.01115051510.99 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
244 schema:familyName Lopez-Berenstein
245 schema:givenName Gabriel
246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115051510.99
247 rdf:type schema:Person
248 sg:person.01160523062.28 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
249 schema:familyName Bar-Eli
250 schema:givenName Menashe
251 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01160523062.28
252 rdf:type schema:Person
253 sg:person.01176437025.21 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
254 schema:familyName Calin
255 schema:givenName George
256 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01176437025.21
257 rdf:type schema:Person
258 sg:person.012350726577.33 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
259 schema:familyName Huang
260 schema:givenName Li
261 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012350726577.33
262 rdf:type schema:Person
263 sg:person.01257563174.54 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
264 schema:familyName Rodriguez-Aguayo
265 schema:givenName Cristian
266 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257563174.54
267 rdf:type schema:Person
268 sg:person.01317617201.88 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
269 schema:familyName Fuentes-Mattei
270 schema:givenName Enrique
271 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317617201.88
272 rdf:type schema:Person
273 sg:person.01342026204.71 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
274 schema:familyName Xie
275 schema:givenName Victoria
276 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342026204.71
277 rdf:type schema:Person
278 sg:person.01344724200.05 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
279 schema:familyName Shoshan
280 schema:givenName Einav
281 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01344724200.05
282 rdf:type schema:Person
283 sg:person.01354560625.68 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
284 schema:familyName Ivan
285 schema:givenName Cristina
286 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354560625.68
287 rdf:type schema:Person
288 sg:person.014375355307.61 schema:affiliation https://www.grid.ac/institutes/grid.240145.6
289 schema:familyName Kim
290 schema:givenName Sun Jin
291 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014375355307.61
292 rdf:type schema:Person
293 sg:pub.10.1007/s00018-005-5355-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045832152
294 https://doi.org/10.1007/s00018-005-5355-1
295 rdf:type schema:CreativeWork
296 sg:pub.10.1007/s10549-014-2859-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037631377
297 https://doi.org/10.1007/s10549-014-2859-0
298 rdf:type schema:CreativeWork
299 sg:pub.10.1007/s13277-015-3996-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018800013
300 https://doi.org/10.1007/s13277-015-3996-8
301 rdf:type schema:CreativeWork
302 sg:pub.10.1007/s13277-015-4710-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018249828
303 https://doi.org/10.1007/s13277-015-4710-6
304 rdf:type schema:CreativeWork
305 sg:pub.10.1038/ncb3110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037204646
306 https://doi.org/10.1038/ncb3110
307 rdf:type schema:CreativeWork
308 sg:pub.10.1038/ncomms10993 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017154708
309 https://doi.org/10.1038/ncomms10993
310 rdf:type schema:CreativeWork
311 sg:pub.10.1038/ng.3694 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042300353
312 https://doi.org/10.1038/ng.3694
313 rdf:type schema:CreativeWork
314 sg:pub.10.1038/nrm1789 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036759909
315 https://doi.org/10.1038/nrm1789
316 rdf:type schema:CreativeWork
317 sg:pub.10.1038/sj.onc.1201358 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037217388
318 https://doi.org/10.1038/sj.onc.1201358
319 rdf:type schema:CreativeWork
320 sg:pub.10.1038/srep19455 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049246797
321 https://doi.org/10.1038/srep19455
322 rdf:type schema:CreativeWork
323 https://app.dimensions.ai/details/publication/pub.1077605660 schema:CreativeWork
324 https://app.dimensions.ai/details/publication/pub.1079131351 schema:CreativeWork
325 https://doi.org/10.1002/hep.26396 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050860270
326 rdf:type schema:CreativeWork
327 https://doi.org/10.1074/jbc.273.38.24884 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043567766
328 rdf:type schema:CreativeWork
329 https://doi.org/10.1074/jbc.m109.019836 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014490168
330 rdf:type schema:CreativeWork
331 https://doi.org/10.1074/jbc.m112.385229 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026359223
332 rdf:type schema:CreativeWork
333 https://doi.org/10.1074/jbc.m508683200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005252934
334 rdf:type schema:CreativeWork
335 https://doi.org/10.1083/jcb.142.3.827 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047165335
336 rdf:type schema:CreativeWork
337 https://doi.org/10.1158/0008-5472.can-05-0530 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030443527
338 rdf:type schema:CreativeWork
339 https://doi.org/10.1172/jci62980 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031724930
340 rdf:type schema:CreativeWork
341 https://doi.org/10.1371/journal.pone.0012452 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032875127
342 rdf:type schema:CreativeWork
343 https://doi.org/10.1371/journal.pone.0118530 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002130722
344 rdf:type schema:CreativeWork
345 https://doi.org/10.3109/07357907.2015.1047508 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035954777
346 rdf:type schema:CreativeWork
347 https://doi.org/10.3322/caac.21387 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014894112
348 rdf:type schema:CreativeWork
349 https://doi.org/10.4161/cbt.7.7.6535 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072295035
350 rdf:type schema:CreativeWork
351 https://www.grid.ac/institutes/grid.240145.6 schema:alternateName The University of Texas MD Anderson Cancer Center
352 schema:name Department of Cancer Biology, Unit 1906, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, 77030, Houston, TX, USA
353 Department of Experimental Therapeutics, Unit 1950, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, 77030, Houston, TX, USA
354 Department of Gynecologic Oncology, Unit 1362, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, TX, USA
355 Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, TX, USA
356 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...