Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-12

AUTHORS

Xia Jiang, Paul F. O’Reilly, Hugues Aschard, Yi-Hsiang Hsu, J. Brent Richards, Josée Dupuis, Erik Ingelsson, David Karasik, Stefan Pilz, Diane Berry, Bryan Kestenbaum, Jusheng Zheng, Jianan Luan, Eleni Sofianopoulou, Elizabeth A. Streeten, Demetrius Albanes, Pamela L. Lutsey, Lu Yao, Weihong Tang, Michael J. Econs, Henri Wallaschofski, Henry Völzke, Ang Zhou, Chris Power, Mark I. McCarthy, Erin D. Michos, Eric Boerwinkle, Stephanie J. Weinstein, Neal D. Freedman, Wen-Yi Huang, Natasja M. Van Schoor, Nathalie van der Velde, Lisette C. P. G. M. de Groot, Anke Enneman, L. Adrienne Cupples, Sarah L. Booth, Ramachandran S. Vasan, Ching-Ti Liu, Yanhua Zhou, Samuli Ripatti, Claes Ohlsson, Liesbeth Vandenput, Mattias Lorentzon, Johan G. Eriksson, M. Kyla Shea, Denise K. Houston, Stephen B. Kritchevsky, Yongmei Liu, Kurt K. Lohman, Luigi Ferrucci, Munro Peacock, Christian Gieger, Marian Beekman, Eline Slagboom, Joris Deelen, Diana van Heemst, Marcus E. Kleber, Winfried März, Ian H. de Boer, Alexis C. Wood, Jerome I. Rotter, Stephen S. Rich, Cassianne Robinson-Cohen, Martin den Heijer, Marjo-Riitta Jarvelin, Alana Cavadino, Peter K. Joshi, James F. Wilson, Caroline Hayward, Lars Lind, Karl Michaëlsson, Stella Trompet, M. Carola Zillikens, Andre G. Uitterlinden, Fernando Rivadeneira, Linda Broer, Lina Zgaga, Harry Campbell, Evropi Theodoratou, Susan M. Farrington, Maria Timofeeva, Malcolm G. Dunlop, Ana M. Valdes, Emmi Tikkanen, Terho Lehtimäki, Leo-Pekka Lyytikäinen, Mika Kähönen, Olli T. Raitakari, Vera Mikkilä, M. Arfan Ikram, Naveed Sattar, J. Wouter Jukema, Nicholas J. Wareham, Claudia Langenberg, Nita G. Forouhi, Thomas E. Gundersen, Kay-Tee Khaw, Adam S. Butterworth, John Danesh, Timothy Spector, Thomas J. Wang, Elina Hyppönen, Peter Kraft, Douglas P. Kiel

ABSTRACT

Vitamin D is a steroid hormone precursor that is associated with a range of human traits and diseases. Previous GWAS of serum 25-hydroxyvitamin D concentrations have identified four genome-wide significant loci (GC, NADSYN1/DHCR7, CYP2R1, CYP24A1). In this study, we expand the previous SUNLIGHT Consortium GWAS discovery sample size from 16,125 to 79,366 (all European descent). This larger GWAS yields two additional loci harboring genome-wide significant variants (P = 4.7×10-9 at rs8018720 in SEC23A, and P = 1.9×10-14 at rs10745742 in AMDHD1). The overall estimate of heritability of 25-hydroxyvitamin D serum concentrations attributable to GWAS common SNPs is 7.5%, with statistically significant loci explaining 38% of this total. Further investigation identifies signal enrichment in immune and hematopoietic tissues, and clustering with autoimmune diseases in cell-type-specific analysis. Larger studies are required to identify additional common SNPs, and to explore the role of rare or structural variants and gene-gene interactions in the heritability of circulating 25-hydroxyvitamin D levels. More... »

PAGES

260

References to SciGraph publications

  • 2013-11. Discovery and refinement of loci associated with lipid levels in NATURE GENETICS
  • 2013-10. The Implication of Vitamin D and Autoimmunity: a Comprehensive Review in CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
  • 2015-03. LD Score regression distinguishes confounding from polygenicity in genome-wide association studies in NATURE GENETICS
  • 2013-02. Chromatin marks identify critical cell types for fine mapping complex trait variants in NATURE GENETICS
  • 2015-12. International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways in NATURE COMMUNICATIONS
  • 2006-10. Cranio-lenticulo-sutural dysplasia is caused by a SEC23A mutation leading to abnormal endoplasmic-reticulum-to-Golgi trafficking in NATURE GENETICS
  • 2014-10. A genome-wide association study of anorexia nervosa in MOLECULAR PSYCHIATRY
  • 2015-02. Integrative analysis of 111 reference human epigenomes in NATURE
  • 2010-05. Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior in NATURE GENETICS
  • 2016-06. Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses in NATURE GENETICS
  • 2014-07. Biological insights from 108 schizophrenia-associated genetic loci in NATURE
  • 2013-10. Vitamin D in Systemic and Organ-Specific Autoimmune Diseases in CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
  • 2011-10. A high-resolution map of human evolutionary constraint using 29 mammals in NATURE
  • 2011-06. Well-Differentiated Liposarcoma of the Oesophagus: Clinicopathological, Immunohistochemical and Array CGH Analysis in PATHOLOGY & ONCOLOGY RESEARCH
  • 2015-12. Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus in NATURE GENETICS
  • 2016-07. Vitamin D and cardiovascular disease prevention in NATURE REVIEWS CARDIOLOGY
  • 2014-03. An atlas of active enhancers across human cell types and tissues in NATURE
  • 2016-07. Detection and interpretation of shared genetic influences on 42 human traits in NATURE GENETICS
  • 2011-03-06. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease in NATURE GENETICS
  • 2012-09. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes in NATURE GENETICS
  • 2014-02. Genetics of rheumatoid arthritis contributes to biology and drug discovery in NATURE
  • 2012-09. An integrated encyclopedia of DNA elements in the human genome in NATURE
  • 2010-04. Multiple common variants for celiac disease influencing immune gene expression in NATURE GENETICS
  • 2012-11. Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease in NATURE
  • 2012-04. Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits in NATURE GENETICS
  • 2015-11. Partitioning heritability by functional annotation using genome-wide association summary statistics in NATURE GENETICS
  • 2011-10. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4 in NATURE GENETICS
  • Journal

    TITLE

    Nature Communications

    ISSUE

    1

    VOLUME

    9

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/s41467-017-02662-2

    DOI

    http://dx.doi.org/10.1038/s41467-017-02662-2

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1100320496

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/29343764


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Genetics", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Amidohydrolases", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Autoimmune Diseases", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cohort Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "European Continental Ancestry Group", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genome-Wide Association Study", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Male", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Polymorphism, Single Nucleotide", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Vesicular Transport Proteins", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Vitamin D", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Karolinska Institute", 
              "id": "https://www.grid.ac/institutes/grid.4714.6", 
              "name": [
                "Program in Genetic Epidemiology and Statistical Genetics. Department of Epidemiology, Harvard T.H.Chan School of Public Health, 677 Huntington Avenue, 02115, Boston, MA, USA", 
                "Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Nobels vagen 13, 17177, Stockholm, Sweden"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Jiang", 
            "givenName": "Xia", 
            "id": "sg:person.01306434164.83", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01306434164.83"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "King's College London", 
              "id": "https://www.grid.ac/institutes/grid.13097.3c", 
              "name": [
                "Department of Social Genetic & Developmental Psychiatry, King\u2019s College London, Institute of Psychiatry, De Crespigny Park, SE5 8AF, London, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "O\u2019Reilly", 
            "givenName": "Paul F.", 
            "id": "sg:person.0664341505.44", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0664341505.44"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Institut Pasteur", 
              "id": "https://www.grid.ac/institutes/grid.428999.7", 
              "name": [
                "Program in Genetic Epidemiology and Statistical Genetics. Department of Epidemiology, Harvard T.H.Chan School of Public Health, 677 Huntington Avenue, 02115, Boston, MA, USA", 
                "Centre de Bioinformatique, Biostatistique et Biologie Int\u00e9grative (C3BI), Institut Pasteur, 75724, Paris, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Aschard", 
            "givenName": "Hugues", 
            "id": "sg:person.01066607126.16", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01066607126.16"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Broad Institute", 
              "id": "https://www.grid.ac/institutes/grid.66859.34", 
              "name": [
                "Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, 02131, Boston, MA, USA", 
                "Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, 02115, Boston, MA, USA", 
                "Broad Institute of Harvard and Massachusetts Institute of Technology, 02142, Boston, MA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hsu", 
            "givenName": "Yi-Hsiang", 
            "id": "sg:person.01327765331.73", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01327765331.73"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Departments of Medicine, Human Genetics, Epidemiology and Biostatistics, 3755 C\u00f4te Ste-Catherine Road, Suite H-413 Montr\u00e9al, H3T 1E2, Qu\u00e9bec, Canada"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Richards", 
            "givenName": "J. Brent", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Boston University", 
              "id": "https://www.grid.ac/institutes/grid.189504.1", 
              "name": [
                "Department of Biostatistics, Boston University School of Public Health, Crosstown Center. 801 Massachusetts Avenue 3rd Floor, 02118, Boston, MA, USA", 
                "Framingham Heart Study, 73 Mt. Wayte Avenue, 01702, Framingham, MA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Dupuis", 
            "givenName": "Jos\u00e9e", 
            "id": "sg:person.01230220117.55", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01230220117.55"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Uppsala University", 
              "id": "https://www.grid.ac/institutes/grid.8993.b", 
              "name": [
                "Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine Stanford, 94305, Stanford, CA, USA", 
                "Department of Medical Sciences, Uppsala University, 751 85, Uppsala, Sweden"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ingelsson", 
            "givenName": "Erik", 
            "id": "sg:person.01145654113.82", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145654113.82"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Harvard University", 
              "id": "https://www.grid.ac/institutes/grid.38142.3c", 
              "name": [
                "Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, 02131, Boston, MA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Karasik", 
            "givenName": "David", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Medical University of Graz", 
              "id": "https://www.grid.ac/institutes/grid.11598.34", 
              "name": [
                "Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Pilz", 
            "givenName": "Stefan", 
            "id": "sg:person.0751717266.10", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0751717266.10"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University College London", 
              "id": "https://www.grid.ac/institutes/grid.83440.3b", 
              "name": [
                "Population, Policy and Practice, University College London, Great Ormond Street, Institute of Child Health, WC1E 6BT, London, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Berry", 
            "givenName": "Diane", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Kidney Research Institute, Division of Nephrology, 325 Ninth Avenue, 98104, Seattle, WA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kestenbaum", 
            "givenName": "Bryan", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Cambridge", 
              "id": "https://www.grid.ac/institutes/grid.5335.0", 
              "name": [
                "MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, CB2 0QQ, Cambridge, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zheng", 
            "givenName": "Jusheng", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Cambridge", 
              "id": "https://www.grid.ac/institutes/grid.5335.0", 
              "name": [
                "MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, CB2 0QQ, Cambridge, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Luan", 
            "givenName": "Jianan", 
            "id": "sg:person.0776707354.45", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0776707354.45"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Cambridge", 
              "id": "https://www.grid.ac/institutes/grid.5335.0", 
              "name": [
                "Department of Public Health & Primary Care, University of Cambridge, Strangeways Research Laboratory, Wort\u2019s Causeway, CB1 8RN, Cambridge, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sofianopoulou", 
            "givenName": "Eleni", 
            "id": "sg:person.01015660301.22", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015660301.22"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Maryland, Baltimore", 
              "id": "https://www.grid.ac/institutes/grid.411024.2", 
              "name": [
                "Genetics and Personalized Medicine Program, University of Maryland School of Medicine, Howard Hall Room 567, 21201, Baltimore, MD, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Streeten", 
            "givenName": "Elizabeth A.", 
            "id": "sg:person.0604632732.94", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604632732.94"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "National Institute of Arthritis and Musculoskeletal and Skin Diseases", 
              "id": "https://www.grid.ac/institutes/grid.420086.8", 
              "name": [
                "Metabolic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 9609 Medical Center Drive, 20892, Bethesda, MD, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Albanes", 
            "givenName": "Demetrius", 
            "id": "sg:person.01024575002.28", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01024575002.28"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Minnesota", 
              "id": "https://www.grid.ac/institutes/grid.17635.36", 
              "name": [
                "Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, 1300S 2nd Street, Suite 300, 55454, Minneapolis, MN, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lutsey", 
            "givenName": "Pamela L.", 
            "id": "sg:person.011741202517.08", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011741202517.08"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Minnesota", 
              "id": "https://www.grid.ac/institutes/grid.17635.36", 
              "name": [
                "Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, 1300S 2nd Street, Suite 300, 55454, Minneapolis, MN, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Yao", 
            "givenName": "Lu", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Minnesota", 
              "id": "https://www.grid.ac/institutes/grid.17635.36", 
              "name": [
                "Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, 1300S 2nd Street, Suite 300, 55454, Minneapolis, MN, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Tang", 
            "givenName": "Weihong", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Indiana University \u2013 Purdue University Indianapolis", 
              "id": "https://www.grid.ac/institutes/grid.257413.6", 
              "name": [
                "Department of Medicine, Indiana University, Endocrinology, 1120W Michigan Street, 46202-5124, Indianapolis, IN, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Econs", 
            "givenName": "Michael J.", 
            "id": "sg:person.0721676562.69", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721676562.69"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "German Centre for Cardiovascular Research", 
              "id": "https://www.grid.ac/institutes/grid.452396.f", 
              "name": [
                "Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17489, Greifswald, Germany", 
                "DZHK (German Centre for Cardiovascular Research), Partner Site, Greifswald, 13316, Berlin, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wallaschofski", 
            "givenName": "Henri", 
            "id": "sg:person.0754621150.33", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0754621150.33"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Greifswald", 
              "id": "https://www.grid.ac/institutes/grid.5603.0", 
              "name": [
                "DZHK (German Centre for Cardiovascular Research), Partner Site, Greifswald, 13316, Berlin, Germany", 
                "Institut f\u00fcr Community Medicine, SHIP/Klinisch-Epidemiologische Forschung, Universit\u00e4tsmedizin Greifswald, Walther-Rathenau-Str. 48, 17475, Greifswald, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "V\u00f6lzke", 
            "givenName": "Henry", 
            "id": "sg:person.0712400456.14", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0712400456.14"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of South Australia", 
              "id": "https://www.grid.ac/institutes/grid.1026.5", 
              "name": [
                "Centre for Population Health Research, Sansom Institute for Health Research, University of South Australia, 5001, Adelaide, SA, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zhou", 
            "givenName": "Ang", 
            "id": "sg:person.014511602440.06", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014511602440.06"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University College London", 
              "id": "https://www.grid.ac/institutes/grid.83440.3b", 
              "name": [
                "Population, Policy and Practice, University College London, Great Ormond Street, Institute of Child Health, WC1E 6BT, London, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Power", 
            "givenName": "Chris", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Churchill Hospital", 
              "id": "https://www.grid.ac/institutes/grid.415719.f", 
              "name": [
                "Oxford Centre for Diabetes Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Old Road, Headington, OX3 7LJ, Oxford, UK", 
                "Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Headington, OX3 7BN, Oxford, UK", 
                "Oxford NIHR Biomedical Research Centre, Churchill Hospital, Old Road, Headington, OX3 7LJ, Oxford, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "McCarthy", 
            "givenName": "Mark I.", 
            "id": "sg:person.016704245502.43", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016704245502.43"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "Division of Cardiology, Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins School of Medicine, 21287, Baltimore, MD, USA", 
                "Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 21205, Baltimore, MD, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Michos", 
            "givenName": "Erin D.", 
            "id": "sg:person.01261451553.16", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261451553.16"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "The University of Texas Health Science Center at Houston", 
              "id": "https://www.grid.ac/institutes/grid.267308.8", 
              "name": [
                "Human Genetics Center, University of Texas Health Science Center at Houston, 77030, Houston, TX, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Boerwinkle", 
            "givenName": "Eric", 
            "id": "sg:person.01104262534.26", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01104262534.26"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "National Institute of Arthritis and Musculoskeletal and Skin Diseases", 
              "id": "https://www.grid.ac/institutes/grid.420086.8", 
              "name": [
                "Metabolic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 9609 Medical Center Drive, 20892, Bethesda, MD, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Weinstein", 
            "givenName": "Stephanie J.", 
            "id": "sg:person.01006015331.07", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01006015331.07"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "National Institute of Arthritis and Musculoskeletal and Skin Diseases", 
              "id": "https://www.grid.ac/institutes/grid.420086.8", 
              "name": [
                "Metabolic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 9609 Medical Center Drive, 20892, Bethesda, MD, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Freedman", 
            "givenName": "Neal D.", 
            "id": "sg:person.01114645561.56", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114645561.56"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "National Institute of Arthritis and Musculoskeletal and Skin Diseases", 
              "id": "https://www.grid.ac/institutes/grid.420086.8", 
              "name": [
                "Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 9609 Medical Center Drive, 20892, Bethesda, MD, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Huang", 
            "givenName": "Wen-Yi", 
            "id": "sg:person.012213174274.48", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012213174274.48"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "VU University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.16872.3a", 
              "name": [
                "Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, VU University Medical Center, De Boelelaan 1089a, 1081 HV, Amsterdam, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Van Schoor", 
            "givenName": "Natasja M.", 
            "id": "sg:person.01356554174.39", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356554174.39"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Academic Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.5650.6", 
              "name": [
                "Erasmus MC Department of Epidemiology, Postbus 2040, 3000CA, Rotterdam, The Netherlands", 
                "AMC, Internal Medicine, Geriatrics Department, PO Box 22700, 1100 DE, Amsterdam, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "van der Velde", 
            "givenName": "Nathalie", 
            "id": "sg:person.01236775365.34", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01236775365.34"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Wageningen University & Research", 
              "id": "https://www.grid.ac/institutes/grid.4818.5", 
              "name": [
                "Department of Human Nutrition, Wageningen University, PO-box 17, 6700 AA, Wageningen, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "de Groot", 
            "givenName": "Lisette C. P. G. M.", 
            "id": "sg:person.010047240537.27", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010047240537.27"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Erasmus University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.5645.2", 
              "name": [
                "Erasmus MC Department of Epidemiology, Postbus 2040, 3000CA, Rotterdam, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Enneman", 
            "givenName": "Anke", 
            "id": "sg:person.0747376474.29", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0747376474.29"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Boston University", 
              "id": "https://www.grid.ac/institutes/grid.189504.1", 
              "name": [
                "Department of Biostatistics, Boston University School of Public Health, Crosstown Center. 801 Massachusetts Avenue 3rd Floor, 02118, Boston, MA, USA", 
                "Framingham Heart Study, 73 Mt. Wayte Avenue, 01702, Framingham, MA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Cupples", 
            "givenName": "L. Adrienne", 
            "id": "sg:person.01365531352.22", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365531352.22"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Tufts University", 
              "id": "https://www.grid.ac/institutes/grid.429997.8", 
              "name": [
                "Vitamin K Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, 02111, Boston, MA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Booth", 
            "givenName": "Sarah L.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Framingham Heart Study, 73 Mt. Wayte Avenue, 01702, Framingham, MA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Vasan", 
            "givenName": "Ramachandran S.", 
            "id": "sg:person.01313052166.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313052166.05"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Boston University", 
              "id": "https://www.grid.ac/institutes/grid.189504.1", 
              "name": [
                "Department of Biostatistics, Boston University School of Public Health, Crosstown Center. 801 Massachusetts Avenue 3rd Floor, 02118, Boston, MA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Liu", 
            "givenName": "Ching-Ti", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Boston University", 
              "id": "https://www.grid.ac/institutes/grid.189504.1", 
              "name": [
                "Department of Biostatistics, Boston University School of Public Health, Crosstown Center. 801 Massachusetts Avenue 3rd Floor, 02118, Boston, MA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zhou", 
            "givenName": "Yanhua", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Helsinki", 
              "id": "https://www.grid.ac/institutes/grid.7737.4", 
              "name": [
                "Statistical and Translational Genetics, University of Helsinki, Tukholmankatu 8, Building, Biomedicum, Helsinki 2U, Finland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ripatti", 
            "givenName": "Samuli", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Gothenburg", 
              "id": "https://www.grid.ac/institutes/grid.8761.8", 
              "name": [
                "Department of Internal Medicine and Clinical Nutrition, University of Gothenburg, Vita Str\u00e5ket 11, 41345, Gothenburg, Sweden"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ohlsson", 
            "givenName": "Claes", 
            "id": "sg:person.01031064300.74", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031064300.74"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Gothenburg", 
              "id": "https://www.grid.ac/institutes/grid.8761.8", 
              "name": [
                "Department of Internal Medicine and Clinical Nutrition, University of Gothenburg, Vita Str\u00e5ket 11, 41345, Gothenburg, Sweden"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Vandenput", 
            "givenName": "Liesbeth", 
            "id": "sg:person.0727423345.30", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0727423345.30"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Department of Geriatric Medicine, University of Gothenburg and Sahlgrenska University Hospital, 43180, M\u00f6lndal, Sweden"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lorentzon", 
            "givenName": "Mattias", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Helsinki", 
              "id": "https://www.grid.ac/institutes/grid.7737.4", 
              "name": [
                "Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, University of Helsinki, P.O. Box 20, 8 B 00014, Tukholmankatu, Finland", 
                "Folkh\u00e4lsan Research Center, University of Helsinki, PO Box 2000014, Helsinki, Finland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Eriksson", 
            "givenName": "Johan G.", 
            "id": "sg:person.01242715665.45", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01242715665.45"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Tufts University", 
              "id": "https://www.grid.ac/institutes/grid.429997.8", 
              "name": [
                "Vitamin K Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, 02111, Boston, MA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Shea", 
            "givenName": "M. Kyla", 
            "id": "sg:person.0712704164.77", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0712704164.77"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Sticht Center for Healthy Aging and Alzheimer\u2019s Prevention, Wake Forest School of Medicine, Medical Center Boulevard, 27157, Winston-Salem, NC, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Houston", 
            "givenName": "Denise K.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Sticht Center for Healthy Aging and Alzheimer\u2019s Prevention, Wake Forest School of Medicine, Medical Center Boulevard, 27157, Winston-Salem, NC, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kritchevsky", 
            "givenName": "Stephen B.", 
            "id": "sg:person.016403337057.14", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016403337057.14"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Medical Center Blvd, 27157, Winston-Salem, NC, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Liu", 
            "givenName": "Yongmei", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Medical Center Blvd, 27157, Winston-Salem, NC, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lohman", 
            "givenName": "Kurt K.", 
            "id": "sg:person.0766720170.34", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0766720170.34"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "National Institute on Aging", 
              "id": "https://www.grid.ac/institutes/grid.419475.a", 
              "name": [
                "Longitudinal Studies Section, Intramural Research Program of the National Institute on Aging, NIH, 21225, Baltimore, MD, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ferrucci", 
            "givenName": "Luigi", 
            "id": "sg:person.015356157217.08", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015356157217.08"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Indiana University \u2013 Purdue University Indianapolis", 
              "id": "https://www.grid.ac/institutes/grid.257413.6", 
              "name": [
                "Department of Medicine, Indiana University, Endocrinology, 1120W Michigan Street, 46202-5124, Indianapolis, IN, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Peacock", 
            "givenName": "Munro", 
            "id": "sg:person.01326573405.52", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01326573405.52"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Helmholtz Zentrum M\u00fcnchen", 
              "id": "https://www.grid.ac/institutes/grid.4567.0", 
              "name": [
                "German Research Center for Environmental Health, Molecular Epidemiology, AME, Ingolst\u00e4dter Landstr 1, D-85764, Neuherberg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Gieger", 
            "givenName": "Christian", 
            "id": "sg:person.011673465237.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011673465237.05"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Leiden University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.10419.3d", 
              "name": [
                "Molecular Epidemiology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Beekman", 
            "givenName": "Marian", 
            "id": "sg:person.0657304603.00", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657304603.00"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Leiden University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.10419.3d", 
              "name": [
                "Molecular Epidemiology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Slagboom", 
            "givenName": "Eline", 
            "id": "sg:person.01247550615.12", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01247550615.12"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Max Planck Institute for Biology of Ageing", 
              "id": "https://www.grid.ac/institutes/grid.419502.b", 
              "name": [
                "Molecular Epidemiology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands", 
                "Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Str. 9b, D-50931, K\u00f6ln (Cologne), Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Deelen", 
            "givenName": "Joris", 
            "id": "sg:person.01330734403.13", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01330734403.13"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Leiden University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.10419.3d", 
              "name": [
                "Gerontology and Geriatrics, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "van Heemst", 
            "givenName": "Diana", 
            "id": "sg:person.01353111051.81", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01353111051.81"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Heidelberg University", 
              "id": "https://www.grid.ac/institutes/grid.7700.0", 
              "name": [
                "Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer1, 68167, Mannheim, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kleber", 
            "givenName": "Marcus E.", 
            "id": "sg:person.01341032053.15", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341032053.15"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Medical University of Graz", 
              "id": "https://www.grid.ac/institutes/grid.11598.34", 
              "name": [
                "Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer1, 68167, Mannheim, Germany", 
                "Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Graz, Austria", 
                "SYNLAB Holding Deutschland GmbH, Gubener Stra\u00dfe 39, 86156, Augsburg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "M\u00e4rz", 
            "givenName": "Winfried", 
            "id": "sg:person.01200771067.24", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01200771067.24"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Washington", 
              "id": "https://www.grid.ac/institutes/grid.34477.33", 
              "name": [
                "Division of Nephrology and Kidney Research Institute, University of Washington, 325 ninth Avenue, 98104, Washington, DC, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "de Boer", 
            "givenName": "Ian H.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Agricultural Research Service", 
              "id": "https://www.grid.ac/institutes/grid.463419.d", 
              "name": [
                "USDA/ARS Children\u2019s Nutrition Research Center, 1100 Bates Avenue, 77071, Houston, TX, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wood", 
            "givenName": "Alexis C.", 
            "id": "sg:person.01065702313.98", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01065702313.98"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Harbor\u2013UCLA Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.239844.0", 
              "name": [
                "Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor-UCLA Medical Center, 90502, Torrance, CA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rotter", 
            "givenName": "Jerome I.", 
            "id": "sg:person.012264440652.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012264440652.05"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Virginia", 
              "id": "https://www.grid.ac/institutes/grid.27755.32", 
              "name": [
                "Department of Public Health Sciences, University of Virginia, 22908, Charlottesville, VA, USA", 
                "Center for Public Health Genomics, University of Virginia, 22908, Charlottesville, VA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rich", 
            "givenName": "Stephen S.", 
            "id": "sg:person.015565463537.09", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015565463537.09"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Vanderbilt University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.412807.8", 
              "name": [
                "Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, 1161 21st Ave S., 37232, Nashville, TN, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Robinson-Cohen", 
            "givenName": "Cassianne", 
            "id": "sg:person.013165261347.40", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013165261347.40"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Erasmus University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.5645.2", 
              "name": [
                "Erasmus MC Department of Internal Medicine, Postbus 2040, 3000CA, Rotterdam, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Heijer", 
            "givenName": "Martin den", 
            "id": "sg:person.015732055741.64", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015732055741.64"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Oulu University Hospital", 
              "id": "https://www.grid.ac/institutes/grid.412326.0", 
              "name": [
                "Epidemiology and Biostatistics School of Public Health, Imperial College London, 156 Norfolk Place, St. Mary\u2019s Campus, UK W2 1PG, London, UK", 
                "Center for Life Course Health Research, Faculty of Medicine, University of Oulu, 90014, Oulu, Finland", 
                "Biocenter Oulu, University of Oulu, P.O. Box 5000, FI-90014, Aapistie 5A, Finland", 
                "Unit of Primary Care, Oulu University Hospital, P.O. Box 20, FI-90220 Oulu, 90029 OYS, Kajaanintie 50, Finland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Jarvelin", 
            "givenName": "Marjo-Riitta", 
            "id": "sg:person.015301404517.88", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015301404517.88"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Queen Mary University of London", 
              "id": "https://www.grid.ac/institutes/grid.4868.2", 
              "name": [
                "Population, Policy and Practice, University College London, Great Ormond Street, Institute of Child Health, WC1E 6BT, London, UK", 
                "Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, EC1M 6BQ, London, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Cavadino", 
            "givenName": "Alana", 
            "id": "sg:person.01131101310.00", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01131101310.00"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Edinburgh", 
              "id": "https://www.grid.ac/institutes/grid.4305.2", 
              "name": [
                "Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, EH8 9AG, Edinburgh, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Joshi", 
            "givenName": "Peter K.", 
            "id": "sg:person.0763100407.41", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0763100407.41"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Edinburgh", 
              "id": "https://www.grid.ac/institutes/grid.4305.2", 
              "name": [
                "Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, EH8 9AG, Edinburgh, UK", 
                "MRC Human Genetics Unit, MRC Institute of Genetics & Molecular Medicine, the University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wilson", 
            "givenName": "James F.", 
            "id": "sg:person.01060172311.14", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060172311.14"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "MRC Human Genetics Unit, MRC Institute of Genetics & Molecular Medicine, the University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hayward", 
            "givenName": "Caroline", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Uppsala University", 
              "id": "https://www.grid.ac/institutes/grid.8993.b", 
              "name": [
                "Department of Medical Sciences, Uppsala University, 751 85, Uppsala, Sweden"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lind", 
            "givenName": "Lars", 
            "id": "sg:person.01003275415.57", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01003275415.57"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Uppsala University", 
              "id": "https://www.grid.ac/institutes/grid.8993.b", 
              "name": [
                "Department of Surgical Sciences, Uppsala University, Dag Hammarskj\u00f6ldsv 14 B, Uppsala Science Park, 751 85, Uppsala, Sweden"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Micha\u00eblsson", 
            "givenName": "Karl", 
            "id": "sg:person.0724034436.28", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0724034436.28"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Leiden University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.10419.3d", 
              "name": [
                "Gerontology and Geriatrics, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands", 
                "Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Trompet", 
            "givenName": "Stella", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Erasmus University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.5645.2", 
              "name": [
                "Erasmus MC Department of Internal Medicine, Postbus 2040, 3000CA, Rotterdam, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zillikens", 
            "givenName": "M. Carola", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Erasmus University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.5645.2", 
              "name": [
                "Erasmus MC Department of Epidemiology, Postbus 2040, 3000CA, Rotterdam, The Netherlands", 
                "Erasmus MC Department of Internal Medicine, Postbus 2040, 3000CA, Rotterdam, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Uitterlinden", 
            "givenName": "Andre G.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Erasmus University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.5645.2", 
              "name": [
                "Erasmus MC Department of Epidemiology, Postbus 2040, 3000CA, Rotterdam, The Netherlands", 
                "Erasmus MC Department of Internal Medicine, Postbus 2040, 3000CA, Rotterdam, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rivadeneira", 
            "givenName": "Fernando", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Erasmus University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.5645.2", 
              "name": [
                "Erasmus MC Department of Internal Medicine, Postbus 2040, 3000CA, Rotterdam, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Broer", 
            "givenName": "Linda", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Trinity College Dublin", 
              "id": "https://www.grid.ac/institutes/grid.8217.c", 
              "name": [
                "Department of Public Health and Primary Care, Institute of Population Health, Trinity College Dublin, University of Dublin, D02 PN40, Dublin 24, Ireland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zgaga", 
            "givenName": "Lina", 
            "id": "sg:person.01114232756.11", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114232756.11"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Edinburgh", 
              "id": "https://www.grid.ac/institutes/grid.4305.2", 
              "name": [
                "Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, EH8 9AG, Edinburgh, UK", 
                "Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Campbell", 
            "givenName": "Harry", 
            "id": "sg:person.01262170300.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01262170300.25"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Edinburgh", 
              "id": "https://www.grid.ac/institutes/grid.4305.2", 
              "name": [
                "Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, EH8 9AG, Edinburgh, UK", 
                "Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Theodoratou", 
            "givenName": "Evropi", 
            "id": "sg:person.011173242767.55", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011173242767.55"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Farrington", 
            "givenName": "Susan M.", 
            "id": "sg:person.012142217732.11", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012142217732.11"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Timofeeva", 
            "givenName": "Maria", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Dunlop", 
            "givenName": "Malcolm G.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "King's College London", 
              "id": "https://www.grid.ac/institutes/grid.13097.3c", 
              "name": [
                "The Department of Twin Research & Genetic Epidemiology, King\u2019s College London, St Thomas\u2019 Campus, Westminster Bridge Road, SE1 7EH, London, UK", 
                "School of Medicine, University of Nottingham, City Hospital, Hucknall Rd, NG5 1PB, Nottingham, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Valdes", 
            "givenName": "Ana M.", 
            "id": "sg:person.0701147373.33", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0701147373.33"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Helsinki", 
              "id": "https://www.grid.ac/institutes/grid.7737.4", 
              "name": [
                "FIMM-Institute for Molecular Medicine Finland, University of Helsinki, P.O. Box 20, FI-00014, Helsinki, Finland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Tikkanen", 
            "givenName": "Emmi", 
            "id": "sg:person.01061362614.78", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01061362614.78"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Tampere", 
              "id": "https://www.grid.ac/institutes/grid.5509.9", 
              "name": [
                "Department of Clinical Chemistry, Fimlab Laboratories, 33520, Tampere, Finland", 
                "Department of Clinical Chemistry, Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Life Sciences, University of Tampere, 33014, Tampere, Finland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lehtim\u00e4ki", 
            "givenName": "Terho", 
            "id": "sg:person.0654341265.88", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0654341265.88"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Tampere", 
              "id": "https://www.grid.ac/institutes/grid.5509.9", 
              "name": [
                "Department of Clinical Chemistry, Fimlab Laboratories, 33520, Tampere, Finland", 
                "Department of Clinical Chemistry, Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Life Sciences, University of Tampere, 33014, Tampere, Finland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lyytik\u00e4inen", 
            "givenName": "Leo-Pekka", 
            "id": "sg:person.01020276562.45", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020276562.45"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Tampere", 
              "id": "https://www.grid.ac/institutes/grid.5509.9", 
              "name": [
                "Department of Clinical Physiology, Tampere University Hospital, 33521, Tampere, Finland", 
                "Department of Clinical Physiology, Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Life Sciences, University of Tampere, 33014, Tampere, Finland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "K\u00e4h\u00f6nen", 
            "givenName": "Mika", 
            "id": "sg:person.01335473265.62", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335473265.62"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Turku", 
              "id": "https://www.grid.ac/institutes/grid.1374.1", 
              "name": [
                "Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, 20521, Turku, Finland", 
                "Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, 20014, Turku, Finland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Raitakari", 
            "givenName": "Olli T.", 
            "id": "sg:person.01267360065.55", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01267360065.55"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Science Adviser at Academy of Finland, Hakaniemenranta 6, PO Box 131, FI-00531, Helsinki, Finland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Mikkil\u00e4", 
            "givenName": "Vera", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Erasmus University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.5645.2", 
              "name": [
                "Erasmus MC Department of Epidemiology, Postbus 2040, 3000CA, Rotterdam, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ikram", 
            "givenName": "M. Arfan", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, University Avenue, G12 8QQ, Glasgow, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sattar", 
            "givenName": "Naveed", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Leiden University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.10419.3d", 
              "name": [
                "Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, Netherlands", 
                "Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Jukema", 
            "givenName": "J. Wouter", 
            "id": "sg:person.016674701102.75", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016674701102.75"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Cambridge", 
              "id": "https://www.grid.ac/institutes/grid.5335.0", 
              "name": [
                "MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, CB2 0QQ, Cambridge, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wareham", 
            "givenName": "Nicholas J.", 
            "id": "sg:person.013723776517.34", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013723776517.34"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Cambridge", 
              "id": "https://www.grid.ac/institutes/grid.5335.0", 
              "name": [
                "MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, CB2 0QQ, Cambridge, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Langenberg", 
            "givenName": "Claudia", 
            "id": "sg:person.0616003437.07", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0616003437.07"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Cambridge", 
              "id": "https://www.grid.ac/institutes/grid.5335.0", 
              "name": [
                "MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, CB2 0QQ, Cambridge, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Forouhi", 
            "givenName": "Nita G.", 
            "id": "sg:person.0621621022.09", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0621621022.09"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Vitas (Norway)", 
              "id": "https://www.grid.ac/institutes/grid.439075.c", 
              "name": [
                "Vitas AS, Gaustadaleen 21, N-0349, Oslo, Norway"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Gundersen", 
            "givenName": "Thomas E.", 
            "id": "sg:person.01150747020.74", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150747020.74"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Cambridge", 
              "id": "https://www.grid.ac/institutes/grid.5335.0", 
              "name": [
                "Department of Public Health & Primary Care, University of Cambridge, Strangeways Research Laboratory, Wort\u2019s Causeway, CB1 8RN, Cambridge, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Khaw", 
            "givenName": "Kay-Tee", 
            "id": "sg:person.015521617657.37", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015521617657.37"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Cambridge", 
              "id": "https://www.grid.ac/institutes/grid.5335.0", 
              "name": [
                "Department of Public Health & Primary Care, University of Cambridge, Strangeways Research Laboratory, Wort\u2019s Causeway, CB1 8RN, Cambridge, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Butterworth", 
            "givenName": "Adam S.", 
            "id": "sg:person.01132715706.47", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01132715706.47"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Wellcome Sanger Institute", 
              "id": "https://www.grid.ac/institutes/grid.10306.34", 
              "name": [
                "Department of Public Health & Primary Care, University of Cambridge, Strangeways Research Laboratory, Wort\u2019s Causeway, CB1 8RN, Cambridge, UK", 
                "Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, CB10 1SA, Cambridge, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Danesh", 
            "givenName": "John", 
            "id": "sg:person.01367711150.31", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01367711150.31"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "King's College London", 
              "id": "https://www.grid.ac/institutes/grid.13097.3c", 
              "name": [
                "The Department of Twin Research & Genetic Epidemiology, King\u2019s College London, St Thomas\u2019 Campus, Westminster Bridge Road, SE1 7EH, London, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Spector", 
            "givenName": "Timothy", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Vanderbilt University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.412807.8", 
              "name": [
                "Division of Cardiovascular Medicine, Vanderbilt Heart and Vascular Institute, 2220 Pierce Avenue 383 Preston Research Building, 37232-6300, Nashville, TN, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wang", 
            "givenName": "Thomas J.", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of South Australia", 
              "id": "https://www.grid.ac/institutes/grid.1026.5", 
              "name": [
                "Population, Policy and Practice, University College London, Great Ormond Street, Institute of Child Health, WC1E 6BT, London, UK", 
                "Centre for Population Health Research, Sansom Institute for Health Research, University of South Australia, 5001, Adelaide, SA, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hypp\u00f6nen", 
            "givenName": "Elina", 
            "id": "sg:person.01317660746.45", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317660746.45"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Harvard University", 
              "id": "https://www.grid.ac/institutes/grid.38142.3c", 
              "name": [
                "Program in Genetic Epidemiology and Statistical Genetics. Department of Epidemiology, Harvard T.H.Chan School of Public Health, 677 Huntington Avenue, 02115, Boston, MA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kraft", 
            "givenName": "Peter", 
            "id": "sg:person.07512454234.04", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07512454234.04"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Broad Institute", 
              "id": "https://www.grid.ac/institutes/grid.66859.34", 
              "name": [
                "Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, 02131, Boston, MA, USA", 
                "Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, 02115, Boston, MA, USA", 
                "Broad Institute of Harvard and Massachusetts Institute of Technology, 02142, Boston, MA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kiel", 
            "givenName": "Douglas P.", 
            "id": "sg:person.01003710361.37", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01003710361.37"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/ng.784", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000937327", 
              "https://doi.org/10.1038/ng.784"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.784", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000937327", 
              "https://doi.org/10.1038/ng.784"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1359/jbmr.2001.16.2.371", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001699569"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12253-010-9322-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002075029", 
              "https://doi.org/10.1007/s12253-010-9322-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrcardio.2016.73", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003330595", 
              "https://doi.org/10.1038/nrcardio.2016.73"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3945/ajcn.2010.30176", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003813798"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.psyneuen.2009.05.023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004742978"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/gepi.20546", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005004408"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.2213", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006110604", 
              "https://doi.org/10.1038/ng.2213"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.2383", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011024359", 
              "https://doi.org/10.1038/ng.2383"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12016-013-8361-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011043576", 
              "https://doi.org/10.1007/s12016-013-8361-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2013.09.053", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011111923"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature10530", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013402885", 
              "https://doi.org/10.1038/nature10530"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.943", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014682139", 
              "https://doi.org/10.1038/ng.943"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1017/thg.2014.70", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015154270"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/gks1284", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016676991"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.3434", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020046043", 
              "https://doi.org/10.1038/ng.3434"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature13595", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021916306", 
              "https://doi.org/10.1038/nature13595"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature12787", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022158752", 
              "https://doi.org/10.1038/nature12787"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gr.229102", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022792016"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/db10-1656", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022907614"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/gepi.21989", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023769094"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1399-0004.2010.01550.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028946770"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/ddq155", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029039763"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature11247", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029065430", 
              "https://doi.org/10.1038/nature11247"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/nxg.0000000000000097", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029195307"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/nxg.0000000000000097", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029195307"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature14248", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031836937", 
              "https://doi.org/10.1038/nature14248"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.2797", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031899225", 
              "https://doi.org/10.1038/ng.2797"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.3570", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031947374", 
              "https://doi.org/10.1038/ng.3570"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pmed.1001866", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032282372"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.2504", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033269562", 
              "https://doi.org/10.1038/ng.2504"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.3552", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033380373", 
              "https://doi.org/10.1038/ng.3552"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.3552", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033380373", 
              "https://doi.org/10.1038/ng.3552"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.3404", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033620431", 
              "https://doi.org/10.1038/ng.3404"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng1876", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034270289", 
              "https://doi.org/10.1038/ng1876"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng1876", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034270289", 
              "https://doi.org/10.1038/ng1876"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12016-012-8342-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035787415", 
              "https://doi.org/10.1007/s12016-012-8342-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ncomms9019", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040301690", 
              "https://doi.org/10.1038/ncomms9019"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ncomms9019", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040301690", 
              "https://doi.org/10.1038/ncomms9019"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1046/j.1469-1809.1999.6350429.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040897492"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1225057", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041004956"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/mp.2013.187", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041076958", 
              "https://doi.org/10.1038/mp.2013.187"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/mp.2013.187", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041076958", 
              "https://doi.org/10.1038/mp.2013.187"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature12873", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043116196", 
              "https://doi.org/10.1038/nature12873"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.3211", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044444076", 
              "https://doi.org/10.1038/ng.3211"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(10)60588-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044618640"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature11582", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046541188", 
              "https://doi.org/10.1038/nature11582"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcla.21955", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046554670"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/bioinformatics/btq340", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047276303"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.573", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048010930", 
              "https://doi.org/10.1038/ng.573"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.573", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048010930", 
              "https://doi.org/10.1038/ng.573"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.543", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050960747", 
              "https://doi.org/10.1038/ng.543"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.543", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050960747", 
              "https://doi.org/10.1038/ng.543"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(12)62129-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050992578"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ajhg.2014.10.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053287809"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/gepi.21694", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053504157"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1159/000323318", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053661804"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2008-1532", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064290881"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2105/ajph.2004.045260", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068842573"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/ajcn/88.2.441", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1077687195"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077943216", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/bmj.i6583", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083841792"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/bmj.i6583", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083841792"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ajhg.2017.06.014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090914533"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2018-12", 
        "datePublishedReg": "2018-12-01", 
        "description": "Vitamin D is a steroid hormone precursor that is associated with a range of human traits and diseases. Previous GWAS of serum 25-hydroxyvitamin D concentrations have identified four genome-wide significant loci (GC, NADSYN1/DHCR7, CYP2R1, CYP24A1). In this study, we expand the previous SUNLIGHT Consortium GWAS discovery sample size from 16,125 to 79,366 (all European descent). This larger GWAS yields two additional loci harboring genome-wide significant variants (P\u2009=\u20094.7\u00d710-9 at rs8018720 in SEC23A, and P\u2009=\u20091.9\u00d710-14 at rs10745742 in AMDHD1). The overall estimate of heritability of 25-hydroxyvitamin D serum concentrations attributable to GWAS common SNPs is 7.5%, with statistically significant loci explaining 38% of this total. Further investigation identifies signal enrichment in immune and hematopoietic tissues, and clustering with autoimmune diseases in cell-type-specific analysis. Larger studies are required to identify additional common SNPs, and to explore the role of rare or structural variants and gene-gene interactions in the heritability of circulating 25-hydroxyvitamin D levels.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1038/s41467-017-02662-2", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.3560309", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2755349", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2463275", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2765219", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.5475480", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2786906", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.4294206", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.5141446", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.5140177", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2774591", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.5134440", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.6445883", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.3496493", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.3560622", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.7028443", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2775947", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.5143008", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.6944894", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2439028", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.5072449", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2774057", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.6443219", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1043282", 
            "issn": [
              "2041-1723"
            ], 
            "name": "Nature Communications", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "9"
          }
        ], 
        "name": "Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels", 
        "pagination": "260", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "2d84cf776559bfe9c7876b86bf8de38c3542f823d116c3e6e5d9edd76737fa26"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "29343764"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "101528555"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/s41467-017-02662-2"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1100320496"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/s41467-017-02662-2", 
          "https://app.dimensions.ai/details/publication/pub.1100320496"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T13:17", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000368_0000000368/records_78938_00000000.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://www.nature.com/articles/s41467-017-02662-2"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41467-017-02662-2'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41467-017-02662-2'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41467-017-02662-2'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41467-017-02662-2'


     

    This table displays all metadata directly associated to this object as RDF triples.

    1245 TRIPLES      21 PREDICATES      96 URIs      32 LITERALS      20 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/s41467-017-02662-2 schema:about N0737851a0f8a4252a45e0e2e29a8f2ed
    2 N258834c06987455cbee1c40b01a181ae
    3 N4e34dd6faa2f45bbab6979ed381cad8c
    4 N557b7351db6e4a2a9fd06fd0f5fd9244
    5 N758132f8aa9449c39e0d6aad21e43092
    6 N7ec0120178b342669a9617c63d606e9b
    7 N89a7932a32574fa98d5ac20a6db0e93a
    8 Nb322fd1f14cc441ea1f62e60389483d3
    9 Nb7529e91707542baa660391387a8fd71
    10 Ne4732a346a914a5f83ec2c6fbf184da8
    11 Nf02602a53b50469eab7974e21eb43a5b
    12 anzsrc-for:06
    13 anzsrc-for:0604
    14 schema:author Naf8d99a8fbcc441f905de0a39911efd6
    15 schema:citation sg:pub.10.1007/s12016-012-8342-y
    16 sg:pub.10.1007/s12016-013-8361-3
    17 sg:pub.10.1007/s12253-010-9322-2
    18 sg:pub.10.1038/mp.2013.187
    19 sg:pub.10.1038/nature10530
    20 sg:pub.10.1038/nature11247
    21 sg:pub.10.1038/nature11582
    22 sg:pub.10.1038/nature12787
    23 sg:pub.10.1038/nature12873
    24 sg:pub.10.1038/nature13595
    25 sg:pub.10.1038/nature14248
    26 sg:pub.10.1038/ncomms9019
    27 sg:pub.10.1038/ng.2213
    28 sg:pub.10.1038/ng.2383
    29 sg:pub.10.1038/ng.2504
    30 sg:pub.10.1038/ng.2797
    31 sg:pub.10.1038/ng.3211
    32 sg:pub.10.1038/ng.3404
    33 sg:pub.10.1038/ng.3434
    34 sg:pub.10.1038/ng.3552
    35 sg:pub.10.1038/ng.3570
    36 sg:pub.10.1038/ng.543
    37 sg:pub.10.1038/ng.573
    38 sg:pub.10.1038/ng.784
    39 sg:pub.10.1038/ng.943
    40 sg:pub.10.1038/ng1876
    41 sg:pub.10.1038/nrcardio.2016.73
    42 https://app.dimensions.ai/details/publication/pub.1077943216
    43 https://doi.org/10.1002/gepi.20546
    44 https://doi.org/10.1002/gepi.21694
    45 https://doi.org/10.1002/gepi.21989
    46 https://doi.org/10.1002/jcla.21955
    47 https://doi.org/10.1016/j.ajhg.2014.10.004
    48 https://doi.org/10.1016/j.ajhg.2017.06.014
    49 https://doi.org/10.1016/j.cell.2013.09.053
    50 https://doi.org/10.1016/j.psyneuen.2009.05.023
    51 https://doi.org/10.1016/s0140-6736(10)60588-0
    52 https://doi.org/10.1016/s0140-6736(12)62129-1
    53 https://doi.org/10.1017/thg.2014.70
    54 https://doi.org/10.1046/j.1469-1809.1999.6350429.x
    55 https://doi.org/10.1093/ajcn/88.2.441
    56 https://doi.org/10.1093/bioinformatics/btq340
    57 https://doi.org/10.1093/hmg/ddq155
    58 https://doi.org/10.1093/nar/gks1284
    59 https://doi.org/10.1101/gr.229102
    60 https://doi.org/10.1111/j.1399-0004.2010.01550.x
    61 https://doi.org/10.1126/science.1225057
    62 https://doi.org/10.1136/bmj.i6583
    63 https://doi.org/10.1159/000323318
    64 https://doi.org/10.1210/jc.2008-1532
    65 https://doi.org/10.1212/nxg.0000000000000097
    66 https://doi.org/10.1359/jbmr.2001.16.2.371
    67 https://doi.org/10.1371/journal.pmed.1001866
    68 https://doi.org/10.2105/ajph.2004.045260
    69 https://doi.org/10.2337/db10-1656
    70 https://doi.org/10.3945/ajcn.2010.30176
    71 schema:datePublished 2018-12
    72 schema:datePublishedReg 2018-12-01
    73 schema:description Vitamin D is a steroid hormone precursor that is associated with a range of human traits and diseases. Previous GWAS of serum 25-hydroxyvitamin D concentrations have identified four genome-wide significant loci (GC, NADSYN1/DHCR7, CYP2R1, CYP24A1). In this study, we expand the previous SUNLIGHT Consortium GWAS discovery sample size from 16,125 to 79,366 (all European descent). This larger GWAS yields two additional loci harboring genome-wide significant variants (P = 4.7×10<sup>-9</sup> at rs8018720 in SEC23A, and P = 1.9×10<sup>-14</sup> at rs10745742 in AMDHD1). The overall estimate of heritability of 25-hydroxyvitamin D serum concentrations attributable to GWAS common SNPs is 7.5%, with statistically significant loci explaining 38% of this total. Further investigation identifies signal enrichment in immune and hematopoietic tissues, and clustering with autoimmune diseases in cell-type-specific analysis. Larger studies are required to identify additional common SNPs, and to explore the role of rare or structural variants and gene-gene interactions in the heritability of circulating 25-hydroxyvitamin D levels.
    74 schema:genre research_article
    75 schema:inLanguage en
    76 schema:isAccessibleForFree true
    77 schema:isPartOf N7ee8c77286dd484b91aa9a0a76aa80ba
    78 Ned9920a63c924d07b0a45826fcb63c1c
    79 sg:journal.1043282
    80 schema:name Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels
    81 schema:pagination 260
    82 schema:productId N1c0b0e1a727447e0976a5697f319472d
    83 N24c2886e0dc44b7ea916e9c507ed1cdd
    84 N31794f22ce234a4c846883312b8c66a8
    85 N564242ba48a74ce8bfe2966ebb131a9f
    86 Nec48115e03094a80b22548b06ddbae6c
    87 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100320496
    88 https://doi.org/10.1038/s41467-017-02662-2
    89 schema:sdDatePublished 2019-04-11T13:17
    90 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    91 schema:sdPublisher Nd519408348fe4f93b9c98e43bbb4ceaf
    92 schema:url https://www.nature.com/articles/s41467-017-02662-2
    93 sgo:license sg:explorer/license/
    94 sgo:sdDataset articles
    95 rdf:type schema:ScholarlyArticle
    96 N0171ab4fa53a447a83e275fd189b7dca schema:affiliation https://www.grid.ac/institutes/grid.412807.8
    97 schema:familyName Wang
    98 schema:givenName Thomas J.
    99 rdf:type schema:Person
    100 N01ecc982feb7465ba501de14d339d1ee schema:affiliation https://www.grid.ac/institutes/grid.17635.36
    101 schema:familyName Tang
    102 schema:givenName Weihong
    103 rdf:type schema:Person
    104 N0297f41ca0d84fa8a664e7035245a6e5 rdf:first sg:person.0616003437.07
    105 rdf:rest N6aba7cb383214a17ae8603eba9fc096d
    106 N059471d0ca4c44c887064e13c9d1cf1e rdf:first Na11690eef58e46318fdfdbd5fc822955
    107 rdf:rest Nc77495e9b27d412884dde28745379bb4
    108 N0737851a0f8a4252a45e0e2e29a8f2ed schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    109 schema:name Amidohydrolases
    110 rdf:type schema:DefinedTerm
    111 N073c3c39d2394f519fa793bd3f9d1d67 rdf:first N344eac52fa534aedab6d0aacf78e46d3
    112 rdf:rest N206c91c38d9f42a9a135e7f70f1ab2a0
    113 N08205455e6c84352a4e065e5d6bf5d51 rdf:first Nc854cd9fbad84407960c89e4b1fb56f9
    114 rdf:rest Nae3c66825c0547dba8edc27f4560ef22
    115 N0e95caf4c2f54d688e5fe953a981f9de rdf:first sg:person.01313052166.05
    116 rdf:rest Nfb4304b2221b4635b9b5eb2fe1ba20cb
    117 N0f134a7030644eb69c10f877c3b1028c rdf:first sg:person.0712704164.77
    118 rdf:rest N65e905c1dcb942709523250802bd1d4d
    119 N103720e2c6904bc490f6c9095c3f6c8d rdf:first sg:person.01353111051.81
    120 rdf:rest Ne74382e036594b8fb7f87cd9ce785ce5
    121 N1236bb5390b946da853a632126d35096 schema:affiliation https://www.grid.ac/institutes/grid.34477.33
    122 schema:familyName de Boer
    123 schema:givenName Ian H.
    124 rdf:type schema:Person
    125 N144f3796ed5549ca964c31dcfbf51951 rdf:first sg:person.01006015331.07
    126 rdf:rest N806463f5f658479f9791850dc2018245
    127 N16a6da8046944d8187e7d43920c599a5 rdf:first sg:person.01365531352.22
    128 rdf:rest Nad2cfd4044234fee997d4921abd6d654
    129 N19052fb607cf4c059debb47d2842b816 rdf:first sg:person.01060172311.14
    130 rdf:rest N328f6a66d6b94258b67af77621e3962d
    131 N1ba5040a861546148d6de9a542cb370b schema:affiliation N7a41e2f738184f289251195b46910aba
    132 schema:familyName Timofeeva
    133 schema:givenName Maria
    134 rdf:type schema:Person
    135 N1c0b0e1a727447e0976a5697f319472d schema:name readcube_id
    136 schema:value 2d84cf776559bfe9c7876b86bf8de38c3542f823d116c3e6e5d9edd76737fa26
    137 rdf:type schema:PropertyValue
    138 N1caf53be41f74210b80ecd5a77cf8904 schema:affiliation N6fbf4323b35d4fbbb888b7a4c15fcf0f
    139 schema:familyName Sattar
    140 schema:givenName Naveed
    141 rdf:type schema:Person
    142 N206c91c38d9f42a9a135e7f70f1ab2a0 rdf:first sg:person.01242715665.45
    143 rdf:rest N0f134a7030644eb69c10f877c3b1028c
    144 N24c2886e0dc44b7ea916e9c507ed1cdd schema:name dimensions_id
    145 schema:value pub.1100320496
    146 rdf:type schema:PropertyValue
    147 N258834c06987455cbee1c40b01a181ae schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    148 schema:name Vesicular Transport Proteins
    149 rdf:type schema:DefinedTerm
    150 N29542c3ef7a840a9b1e29b422e73c094 rdf:first sg:person.0712400456.14
    151 rdf:rest Nfab9181157b44df3924616a426d1197e
    152 N295b98b2db0c4d7faeae2cff0952f5f7 schema:affiliation https://www.grid.ac/institutes/grid.10419.3d
    153 schema:familyName Trompet
    154 schema:givenName Stella
    155 rdf:type schema:Person
    156 N2c7c13dbb4a24393b9b50f0fb701188f rdf:first sg:person.01020276562.45
    157 rdf:rest N7ec562c60679447ebf04df3257beef36
    158 N2d3b0b76e9d643758da7f1ac42e51442 rdf:first N30a0b73468db470caca2bb4440b78b98
    159 rdf:rest Nad67838debe9427e89ecf3ed82ff3eed
    160 N30a0b73468db470caca2bb4440b78b98 schema:affiliation N71dd3229d79b4fc0b413d79f3ee72a51
    161 schema:familyName Dunlop
    162 schema:givenName Malcolm G.
    163 rdf:type schema:Person
    164 N31794f22ce234a4c846883312b8c66a8 schema:name nlm_unique_id
    165 schema:value 101528555
    166 rdf:type schema:PropertyValue
    167 N328f6a66d6b94258b67af77621e3962d rdf:first Nd1866590ed3d42678b712034dffdf734
    168 rdf:rest N8daaec7e38a44639a35e32b50f0f3134
    169 N344eac52fa534aedab6d0aacf78e46d3 schema:affiliation Nf9b7566cdbac4f92b1092db5835d5ed6
    170 schema:familyName Lorentzon
    171 schema:givenName Mattias
    172 rdf:type schema:Person
    173 N350f3e80f6604b2aa40318444d8612d7 rdf:first sg:person.01015660301.22
    174 rdf:rest Nee2073e8dce74c31a427fcc818f5b672
    175 N36a6cc137dfb4bbaa7cf4eac9c6a9326 rdf:first sg:person.01236775365.34
    176 rdf:rest Ndc9295412e44422bbf866e360a2ba0e9
    177 N41685d4511834087b2799746c7c0a373 schema:name Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Medical Center Blvd, 27157, Winston-Salem, NC, USA
    178 rdf:type schema:Organization
    179 N4462b29883a24e709167fc6c94dfb16c rdf:first sg:person.0766720170.34
    180 rdf:rest N7377c39b759a4e90bbb598fc542890ef
    181 N476d123262b741a1aa86b60cdd610b47 schema:name Science Adviser at Academy of Finland, Hakaniemenranta 6, PO Box 131, FI-00531, Helsinki, Finland
    182 rdf:type schema:Organization
    183 N485a5edc22ae4efa96dbeccb96bf423c rdf:first N1caf53be41f74210b80ecd5a77cf8904
    184 rdf:rest Nd188521b2d1241bc8dea0a7f8bc90178
    185 N485a6b597d5843b4ab881e5667bc9376 schema:affiliation https://www.grid.ac/institutes/grid.189504.1
    186 schema:familyName Liu
    187 schema:givenName Ching-Ti
    188 rdf:type schema:Person
    189 N4a11395674ca44499e352034e3c15ab1 schema:name Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK
    190 rdf:type schema:Organization
    191 N4d123fd575cc4e5d979e4f084daf0231 schema:name Departments of Medicine, Human Genetics, Epidemiology and Biostatistics, 3755 Côte Ste-Catherine Road, Suite H-413 Montréal, H3T 1E2, Québec, Canada
    192 rdf:type schema:Organization
    193 N4d22391f4f9b458882767cb4d8c36ce1 rdf:first Ncadc280d19bf45709a8f64e769c06217
    194 rdf:rest N08205455e6c84352a4e065e5d6bf5d51
    195 N4e34dd6faa2f45bbab6979ed381cad8c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    196 schema:name Autoimmune Diseases
    197 rdf:type schema:DefinedTerm
    198 N52420e4c491743bf97636c71c92dae3c rdf:first sg:person.01150747020.74
    199 rdf:rest N97adfbebd11149e38511edf9c38a6ee2
    200 N557b7351db6e4a2a9fd06fd0f5fd9244 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    201 schema:name European Continental Ancestry Group
    202 rdf:type schema:DefinedTerm
    203 N564242ba48a74ce8bfe2966ebb131a9f schema:name pubmed_id
    204 schema:value 29343764
    205 rdf:type schema:PropertyValue
    206 N5876feaafcf54b899838e3ea9a748e56 rdf:first sg:person.011173242767.55
    207 rdf:rest N74ef767ac4c5408b9f6b3bcb5b75961e
    208 N58a9f4dfa1e5483e957be228943511a2 rdf:first sg:person.013723776517.34
    209 rdf:rest N0297f41ca0d84fa8a664e7035245a6e5
    210 N5acaf725a9da4f9d9489f4ed2cc3e84d schema:affiliation https://www.grid.ac/institutes/grid.5645.2
    211 schema:familyName Zillikens
    212 schema:givenName M. Carola
    213 rdf:type schema:Person
    214 N601e537b2e2c4695868c19931ba49455 rdf:first sg:person.01327765331.73
    215 rdf:rest Nf5c65bcc725b47dca897ebb7ea14dae7
    216 N612565f320034a9aa7b9bc91104bd23e rdf:first N7d74ec6295e543f8873f7f0abca77646
    217 rdf:rest N059471d0ca4c44c887064e13c9d1cf1e
    218 N613202a264e6495487a8ddc78adaec9a rdf:first sg:person.01317660746.45
    219 rdf:rest N9ac84caeae3c4025af6602bf85a0612a
    220 N615b6ba2486046c08a231aa17722a93d rdf:first sg:person.01230220117.55
    221 rdf:rest Nfd5fa625cf5340b18e27c8631eed2fc5
    222 N620bc3b1f9994d678280e5ebc333a8f0 rdf:first sg:person.01066607126.16
    223 rdf:rest N601e537b2e2c4695868c19931ba49455
    224 N63c9db6057e240e59f54dd9193975327 rdf:first sg:person.016704245502.43
    225 rdf:rest Nbd905f6a164249918553cd5dd8ee3155
    226 N643c18edfad44741b8011da16febfd86 rdf:first sg:person.012264440652.05
    227 rdf:rest Nc78d18bb3d9f4befb68e45d1e909b12c
    228 N65e905c1dcb942709523250802bd1d4d rdf:first Nc4d6ae700d1444bb8dfdaec7a8cf4ae5
    229 rdf:rest N8e8e217d2e5d435481d43d0761e58503
    230 N667604828fe0469da776eb59df590090 rdf:first sg:person.01003710361.37
    231 rdf:rest rdf:nil
    232 N672072d59a8f4ca4869e455783bb2930 rdf:first N295b98b2db0c4d7faeae2cff0952f5f7
    233 rdf:rest Nb2c15542601c4b96aa6d2252128ef7fe
    234 N67e431ca6aa5468e9043187198655c9e rdf:first sg:person.011673465237.05
    235 rdf:rest Nc664ce6a053c406fab14ce145046537c
    236 N6aba7cb383214a17ae8603eba9fc096d rdf:first sg:person.0621621022.09
    237 rdf:rest N52420e4c491743bf97636c71c92dae3c
    238 N6c041871a7be492ca2cdc1d4b3763dd2 rdf:first N8378833bba6d4fd490cf40f579cd6f69
    239 rdf:rest N731e3bd2d9644fe09b04a8898692fd3e
    240 N6d05d7c09de3409884a3dfc781cfac88 schema:affiliation N4d123fd575cc4e5d979e4f084daf0231
    241 schema:familyName Richards
    242 schema:givenName J. Brent
    243 rdf:type schema:Person
    244 N6e4baee8a6ca4529b4c367535ed43918 rdf:first sg:person.012213174274.48
    245 rdf:rest N92fc880aa8a94e2cac40bfb71e0413ef
    246 N6fbf4323b35d4fbbb888b7a4c15fcf0f schema:name BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, University Avenue, G12 8QQ, Glasgow, UK
    247 rdf:type schema:Organization
    248 N71dbaacbf35f4ff9b594fd4a04acd38e rdf:first sg:person.011741202517.08
    249 rdf:rest Nd6bc6d189b20433f9b61fde1bd8c3fe1
    250 N71dd3229d79b4fc0b413d79f3ee72a51 schema:name Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK
    251 rdf:type schema:Organization
    252 N731e3bd2d9644fe09b04a8898692fd3e rdf:first sg:person.0751717266.10
    253 rdf:rest Nccd0fab6c4b64a9a8fabae9ec7994536
    254 N7377c39b759a4e90bbb598fc542890ef rdf:first sg:person.015356157217.08
    255 rdf:rest Ne0e1bb0c497047a6b37ae2223bc96b5c
    256 N74ef767ac4c5408b9f6b3bcb5b75961e rdf:first sg:person.012142217732.11
    257 rdf:rest Nd9be24623b5f4cbaa64fd8af59477957
    258 N752348eae2ab4fa485928d78a2f89a40 rdf:first sg:person.0664341505.44
    259 rdf:rest N620bc3b1f9994d678280e5ebc333a8f0
    260 N758132f8aa9449c39e0d6aad21e43092 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    261 schema:name Humans
    262 rdf:type schema:DefinedTerm
    263 N77f02bc3f58743a39a2515f24161cb9c rdf:first sg:person.01132715706.47
    264 rdf:rest Nd234cf42ac904f71b10cf05c49c56736
    265 N793e90c70c024597aaa6f9fcbd476ada rdf:first sg:person.01031064300.74
    266 rdf:rest Nb76852de77ef49adb7a95d5586b4107a
    267 N79dca852006945708ceab070ddd6a3c2 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
    268 schema:familyName Spector
    269 schema:givenName Timothy
    270 rdf:type schema:Person
    271 N7a41e2f738184f289251195b46910aba schema:name Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK
    272 rdf:type schema:Organization
    273 N7a84ad03f128420ea4176fa992b12040 rdf:first sg:person.01061362614.78
    274 rdf:rest Nd5446f023fad4c8594d553b69e0d0085
    275 N7cfedc1a9603430e963475178ea41a1d rdf:first N892e7d10a38a45b19da235cf1e1b9669
    276 rdf:rest N793e90c70c024597aaa6f9fcbd476ada
    277 N7d74ec6295e543f8873f7f0abca77646 schema:affiliation Nec8fa0844d534a1e9e35765de438f40f
    278 schema:familyName Kestenbaum
    279 schema:givenName Bryan
    280 rdf:type schema:Person
    281 N7ec0120178b342669a9617c63d606e9b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    282 schema:name Female
    283 rdf:type schema:DefinedTerm
    284 N7ec562c60679447ebf04df3257beef36 rdf:first sg:person.01335473265.62
    285 rdf:rest Nce7eccdcab6e499fb47f5f2e676020ed
    286 N7ee8c77286dd484b91aa9a0a76aa80ba schema:issueNumber 1
    287 rdf:type schema:PublicationIssue
    288 N806463f5f658479f9791850dc2018245 rdf:first sg:person.01114645561.56
    289 rdf:rest N6e4baee8a6ca4529b4c367535ed43918
    290 N81c2761284944f7a9d9ed28c408b288b schema:affiliation https://www.grid.ac/institutes/grid.17635.36
    291 schema:familyName Yao
    292 schema:givenName Lu
    293 rdf:type schema:Person
    294 N8378833bba6d4fd490cf40f579cd6f69 schema:affiliation https://www.grid.ac/institutes/grid.38142.3c
    295 schema:familyName Karasik
    296 schema:givenName David
    297 rdf:type schema:Person
    298 N86204f1bb4f94afd923c4b2685eba7f9 schema:name MRC Human Genetics Unit, MRC Institute of Genetics & Molecular Medicine, the University of Edinburgh, Western General Hospital, EH4 2XU, Edinburgh, UK
    299 rdf:type schema:Organization
    300 N8766fc6743de4467a00a61360dcfa1bf rdf:first sg:person.01104262534.26
    301 rdf:rest N144f3796ed5549ca964c31dcfbf51951
    302 N892e7d10a38a45b19da235cf1e1b9669 schema:affiliation https://www.grid.ac/institutes/grid.7737.4
    303 schema:familyName Ripatti
    304 schema:givenName Samuli
    305 rdf:type schema:Person
    306 N89a7932a32574fa98d5ac20a6db0e93a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    307 schema:name Genome-Wide Association Study
    308 rdf:type schema:DefinedTerm
    309 N8ade176b1af84a6b8a0646036179fb3f rdf:first sg:person.015301404517.88
    310 rdf:rest Nf9c39d590e3e4f578e4dbf0cce2e1ce7
    311 N8daaec7e38a44639a35e32b50f0f3134 rdf:first sg:person.01003275415.57
    312 rdf:rest Ne84a7e9266c44846b587223697240e58
    313 N8e5bc378c6174eefb0a4d853404db811 schema:name Sticht Center for Healthy Aging and Alzheimer’s Prevention, Wake Forest School of Medicine, Medical Center Boulevard, 27157, Winston-Salem, NC, USA
    314 rdf:type schema:Organization
    315 N8e8e217d2e5d435481d43d0761e58503 rdf:first sg:person.016403337057.14
    316 rdf:rest Nb23bd16701224b5996268cfbd5575789
    317 N905b9de2206a4f8f86d70dc3e744ea56 rdf:first N99aae090b22e4edd81bdb59f064ad32e
    318 rdf:rest N63c9db6057e240e59f54dd9193975327
    319 N9261244d89704669b820ea3383571dd2 rdf:first Nf95bb39651264b37a5c35966e4973cbc
    320 rdf:rest N4d22391f4f9b458882767cb4d8c36ce1
    321 N92fc880aa8a94e2cac40bfb71e0413ef rdf:first sg:person.01356554174.39
    322 rdf:rest N36a6cc137dfb4bbaa7cf4eac9c6a9326
    323 N97adfbebd11149e38511edf9c38a6ee2 rdf:first sg:person.015521617657.37
    324 rdf:rest N77f02bc3f58743a39a2515f24161cb9c
    325 N98dccf20595a4ebe87daf0db2e31e8b6 schema:affiliation https://www.grid.ac/institutes/grid.83440.3b
    326 schema:familyName Berry
    327 schema:givenName Diane
    328 rdf:type schema:Person
    329 N99aae090b22e4edd81bdb59f064ad32e schema:affiliation https://www.grid.ac/institutes/grid.83440.3b
    330 schema:familyName Power
    331 schema:givenName Chris
    332 rdf:type schema:Person
    333 N9ac84caeae3c4025af6602bf85a0612a rdf:first sg:person.07512454234.04
    334 rdf:rest N667604828fe0469da776eb59df590090
    335 N9c96964b7897445aa50b46cad84cc318 schema:affiliation https://www.grid.ac/institutes/grid.5645.2
    336 schema:familyName Ikram
    337 schema:givenName M. Arfan
    338 rdf:type schema:Person
    339 N9f967379f2c949beb432dfef160cafee rdf:first sg:person.0754621150.33
    340 rdf:rest N29542c3ef7a840a9b1e29b422e73c094
    341 N9ff9d663bf6a433391be271b0d77d0b2 rdf:first sg:person.0721676562.69
    342 rdf:rest N9f967379f2c949beb432dfef160cafee
    343 Na0f8c8b44cb74e6d8d50e8165573f069 rdf:first sg:person.01024575002.28
    344 rdf:rest N71dbaacbf35f4ff9b594fd4a04acd38e
    345 Na11690eef58e46318fdfdbd5fc822955 schema:affiliation https://www.grid.ac/institutes/grid.5335.0
    346 schema:familyName Zheng
    347 schema:givenName Jusheng
    348 rdf:type schema:Person
    349 Na3bcd33c62424fe3a94501ee1cd0d9fa rdf:first N0171ab4fa53a447a83e275fd189b7dca
    350 rdf:rest N613202a264e6495487a8ddc78adaec9a
    351 Na672ef1f2a2f484b9693187715b996f5 schema:affiliation https://www.grid.ac/institutes/grid.429997.8
    352 schema:familyName Booth
    353 schema:givenName Sarah L.
    354 rdf:type schema:Person
    355 Na8910271d5cd4442a0e9ce3184357345 rdf:first sg:person.01262170300.25
    356 rdf:rest N5876feaafcf54b899838e3ea9a748e56
    357 Na916f180e50f498891bce13d032c9c05 rdf:first sg:person.01330734403.13
    358 rdf:rest N103720e2c6904bc490f6c9095c3f6c8d
    359 Nad2cfd4044234fee997d4921abd6d654 rdf:first Na672ef1f2a2f484b9693187715b996f5
    360 rdf:rest N0e95caf4c2f54d688e5fe953a981f9de
    361 Nad67838debe9427e89ecf3ed82ff3eed rdf:first sg:person.0701147373.33
    362 rdf:rest N7a84ad03f128420ea4176fa992b12040
    363 Nae3c66825c0547dba8edc27f4560ef22 rdf:first sg:person.01114232756.11
    364 rdf:rest Na8910271d5cd4442a0e9ce3184357345
    365 Naf8d99a8fbcc441f905de0a39911efd6 rdf:first sg:person.01306434164.83
    366 rdf:rest N752348eae2ab4fa485928d78a2f89a40
    367 Nb23bd16701224b5996268cfbd5575789 rdf:first Nc9eab1d661e243c2a9b04489a9d43f14
    368 rdf:rest N4462b29883a24e709167fc6c94dfb16c
    369 Nb2c15542601c4b96aa6d2252128ef7fe rdf:first N5acaf725a9da4f9d9489f4ed2cc3e84d
    370 rdf:rest N9261244d89704669b820ea3383571dd2
    371 Nb322fd1f14cc441ea1f62e60389483d3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    372 schema:name Vitamin D
    373 rdf:type schema:DefinedTerm
    374 Nb34c486f67a04f088758fa2af2878002 rdf:first N01ecc982feb7465ba501de14d339d1ee
    375 rdf:rest N9ff9d663bf6a433391be271b0d77d0b2
    376 Nb567dab1201c4d95a2782f7186970bd3 schema:affiliation N476d123262b741a1aa86b60cdd610b47
    377 schema:familyName Mikkilä
    378 schema:givenName Vera
    379 rdf:type schema:Person
    380 Nb7529e91707542baa660391387a8fd71 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    381 schema:name Polymorphism, Single Nucleotide
    382 rdf:type schema:DefinedTerm
    383 Nb76852de77ef49adb7a95d5586b4107a rdf:first sg:person.0727423345.30
    384 rdf:rest N073c3c39d2394f519fa793bd3f9d1d67
    385 Nb780d04849fb4515af8a9d56d49e9966 rdf:first N79dca852006945708ceab070ddd6a3c2
    386 rdf:rest Na3bcd33c62424fe3a94501ee1cd0d9fa
    387 Nb8f6e52f2f474820be6325f63c3c9f61 rdf:first Nb567dab1201c4d95a2782f7186970bd3
    388 rdf:rest Nea8806b687514f1ab0ef6bf6c4365726
    389 Nb9aa50896e474f3b821641d4ff8b1a28 rdf:first sg:person.0747376474.29
    390 rdf:rest N16a6da8046944d8187e7d43920c599a5
    391 Nbd16214a00a84e96968c7fdc30a08b7e schema:name Framingham Heart Study, 73 Mt. Wayte Avenue, 01702, Framingham, MA, USA
    392 rdf:type schema:Organization
    393 Nbd905f6a164249918553cd5dd8ee3155 rdf:first sg:person.01261451553.16
    394 rdf:rest N8766fc6743de4467a00a61360dcfa1bf
    395 Nc4d6ae700d1444bb8dfdaec7a8cf4ae5 schema:affiliation Nde505fd2e5ff44b89b93637e5d8f69b2
    396 schema:familyName Houston
    397 schema:givenName Denise K.
    398 rdf:type schema:Person
    399 Nc5aeda82186c4b5a9e1f207a7e2bd1b7 rdf:first sg:person.013165261347.40
    400 rdf:rest Ncf2f2e516e52424e8f18c84166394478
    401 Nc664ce6a053c406fab14ce145046537c rdf:first sg:person.0657304603.00
    402 rdf:rest Nce0ed50e4d3346cd85a5a5d53873b741
    403 Nc77495e9b27d412884dde28745379bb4 rdf:first sg:person.0776707354.45
    404 rdf:rest N350f3e80f6604b2aa40318444d8612d7
    405 Nc78d18bb3d9f4befb68e45d1e909b12c rdf:first sg:person.015565463537.09
    406 rdf:rest Nc5aeda82186c4b5a9e1f207a7e2bd1b7
    407 Nc854cd9fbad84407960c89e4b1fb56f9 schema:affiliation https://www.grid.ac/institutes/grid.5645.2
    408 schema:familyName Broer
    409 schema:givenName Linda
    410 rdf:type schema:Person
    411 Nc9eab1d661e243c2a9b04489a9d43f14 schema:affiliation Nfb670ab6841745e0849877681e4a5420
    412 schema:familyName Liu
    413 schema:givenName Yongmei
    414 rdf:type schema:Person
    415 Ncadc280d19bf45709a8f64e769c06217 schema:affiliation https://www.grid.ac/institutes/grid.5645.2
    416 schema:familyName Rivadeneira
    417 schema:givenName Fernando
    418 rdf:type schema:Person
    419 Nccd0fab6c4b64a9a8fabae9ec7994536 rdf:first N98dccf20595a4ebe87daf0db2e31e8b6
    420 rdf:rest N612565f320034a9aa7b9bc91104bd23e
    421 Nce0ed50e4d3346cd85a5a5d53873b741 rdf:first sg:person.01247550615.12
    422 rdf:rest Na916f180e50f498891bce13d032c9c05
    423 Nce7eccdcab6e499fb47f5f2e676020ed rdf:first sg:person.01267360065.55
    424 rdf:rest Nb8f6e52f2f474820be6325f63c3c9f61
    425 Ncf2f2e516e52424e8f18c84166394478 rdf:first sg:person.015732055741.64
    426 rdf:rest N8ade176b1af84a6b8a0646036179fb3f
    427 Nd1866590ed3d42678b712034dffdf734 schema:affiliation N86204f1bb4f94afd923c4b2685eba7f9
    428 schema:familyName Hayward
    429 schema:givenName Caroline
    430 rdf:type schema:Person
    431 Nd188521b2d1241bc8dea0a7f8bc90178 rdf:first sg:person.016674701102.75
    432 rdf:rest N58a9f4dfa1e5483e957be228943511a2
    433 Nd234cf42ac904f71b10cf05c49c56736 rdf:first sg:person.01367711150.31
    434 rdf:rest Nb780d04849fb4515af8a9d56d49e9966
    435 Nd519408348fe4f93b9c98e43bbb4ceaf schema:name Springer Nature - SN SciGraph project
    436 rdf:type schema:Organization
    437 Nd5446f023fad4c8594d553b69e0d0085 rdf:first sg:person.0654341265.88
    438 rdf:rest N2c7c13dbb4a24393b9b50f0fb701188f
    439 Nd6bc6d189b20433f9b61fde1bd8c3fe1 rdf:first N81c2761284944f7a9d9ed28c408b288b
    440 rdf:rest Nb34c486f67a04f088758fa2af2878002
    441 Nd9be24623b5f4cbaa64fd8af59477957 rdf:first N1ba5040a861546148d6de9a542cb370b
    442 rdf:rest N2d3b0b76e9d643758da7f1ac42e51442
    443 Ndbba27c5de804649892861d98cfbe968 rdf:first N1236bb5390b946da853a632126d35096
    444 rdf:rest Nf7ff5db6e93a428db36618748cad38b3
    445 Ndc9295412e44422bbf866e360a2ba0e9 rdf:first sg:person.010047240537.27
    446 rdf:rest Nb9aa50896e474f3b821641d4ff8b1a28
    447 Ndd34e12c8a914843b51a963652e35796 schema:affiliation https://www.grid.ac/institutes/grid.189504.1
    448 schema:familyName Zhou
    449 schema:givenName Yanhua
    450 rdf:type schema:Person
    451 Nde505fd2e5ff44b89b93637e5d8f69b2 schema:name Sticht Center for Healthy Aging and Alzheimer’s Prevention, Wake Forest School of Medicine, Medical Center Boulevard, 27157, Winston-Salem, NC, USA
    452 rdf:type schema:Organization
    453 Ne0e1bb0c497047a6b37ae2223bc96b5c rdf:first sg:person.01326573405.52
    454 rdf:rest N67e431ca6aa5468e9043187198655c9e
    455 Ne13b0f7b28c143cb8c517b26204a3540 rdf:first Ndd34e12c8a914843b51a963652e35796
    456 rdf:rest N7cfedc1a9603430e963475178ea41a1d
    457 Ne4732a346a914a5f83ec2c6fbf184da8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    458 schema:name Cohort Studies
    459 rdf:type schema:DefinedTerm
    460 Ne74382e036594b8fb7f87cd9ce785ce5 rdf:first sg:person.01341032053.15
    461 rdf:rest Nf954a2adaf3249fba0306e1483fe6772
    462 Ne84a7e9266c44846b587223697240e58 rdf:first sg:person.0724034436.28
    463 rdf:rest N672072d59a8f4ca4869e455783bb2930
    464 Nea8806b687514f1ab0ef6bf6c4365726 rdf:first N9c96964b7897445aa50b46cad84cc318
    465 rdf:rest N485a5edc22ae4efa96dbeccb96bf423c
    466 Nec48115e03094a80b22548b06ddbae6c schema:name doi
    467 schema:value 10.1038/s41467-017-02662-2
    468 rdf:type schema:PropertyValue
    469 Nec8fa0844d534a1e9e35765de438f40f schema:name Kidney Research Institute, Division of Nephrology, 325 Ninth Avenue, 98104, Seattle, WA, USA
    470 rdf:type schema:Organization
    471 Ned9920a63c924d07b0a45826fcb63c1c schema:volumeNumber 9
    472 rdf:type schema:PublicationVolume
    473 Nee2073e8dce74c31a427fcc818f5b672 rdf:first sg:person.0604632732.94
    474 rdf:rest Na0f8c8b44cb74e6d8d50e8165573f069
    475 Nf02602a53b50469eab7974e21eb43a5b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    476 schema:name Male
    477 rdf:type schema:DefinedTerm
    478 Nf5c65bcc725b47dca897ebb7ea14dae7 rdf:first N6d05d7c09de3409884a3dfc781cfac88
    479 rdf:rest N615b6ba2486046c08a231aa17722a93d
    480 Nf7ff5db6e93a428db36618748cad38b3 rdf:first sg:person.01065702313.98
    481 rdf:rest N643c18edfad44741b8011da16febfd86
    482 Nf954a2adaf3249fba0306e1483fe6772 rdf:first sg:person.01200771067.24
    483 rdf:rest Ndbba27c5de804649892861d98cfbe968
    484 Nf95bb39651264b37a5c35966e4973cbc schema:affiliation https://www.grid.ac/institutes/grid.5645.2
    485 schema:familyName Uitterlinden
    486 schema:givenName Andre G.
    487 rdf:type schema:Person
    488 Nf9b7566cdbac4f92b1092db5835d5ed6 schema:name Department of Geriatric Medicine, University of Gothenburg and Sahlgrenska University Hospital, 43180, Mölndal, Sweden
    489 rdf:type schema:Organization
    490 Nf9c39d590e3e4f578e4dbf0cce2e1ce7 rdf:first sg:person.01131101310.00
    491 rdf:rest Nff6c5b5101a34e8e87b4484644868a06
    492 Nfab9181157b44df3924616a426d1197e rdf:first sg:person.014511602440.06
    493 rdf:rest N905b9de2206a4f8f86d70dc3e744ea56
    494 Nfb4304b2221b4635b9b5eb2fe1ba20cb rdf:first N485a6b597d5843b4ab881e5667bc9376
    495 rdf:rest Ne13b0f7b28c143cb8c517b26204a3540
    496 Nfb670ab6841745e0849877681e4a5420 schema:name Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Medical Center Blvd, 27157, Winston-Salem, NC, USA
    497 rdf:type schema:Organization
    498 Nfd5fa625cf5340b18e27c8631eed2fc5 rdf:first sg:person.01145654113.82
    499 rdf:rest N6c041871a7be492ca2cdc1d4b3763dd2
    500 Nff6c5b5101a34e8e87b4484644868a06 rdf:first sg:person.0763100407.41
    501 rdf:rest N19052fb607cf4c059debb47d2842b816
    502 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    503 schema:name Biological Sciences
    504 rdf:type schema:DefinedTerm
    505 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
    506 schema:name Genetics
    507 rdf:type schema:DefinedTerm
    508 sg:grant.2439028 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    509 rdf:type schema:MonetaryGrant
    510 sg:grant.2463275 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    511 rdf:type schema:MonetaryGrant
    512 sg:grant.2755349 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    513 rdf:type schema:MonetaryGrant
    514 sg:grant.2765219 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    515 rdf:type schema:MonetaryGrant
    516 sg:grant.2774057 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    517 rdf:type schema:MonetaryGrant
    518 sg:grant.2774591 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    519 rdf:type schema:MonetaryGrant
    520 sg:grant.2775947 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    521 rdf:type schema:MonetaryGrant
    522 sg:grant.2786906 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    523 rdf:type schema:MonetaryGrant
    524 sg:grant.3496493 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    525 rdf:type schema:MonetaryGrant
    526 sg:grant.3560309 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    527 rdf:type schema:MonetaryGrant
    528 sg:grant.3560622 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    529 rdf:type schema:MonetaryGrant
    530 sg:grant.4294206 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    531 rdf:type schema:MonetaryGrant
    532 sg:grant.5072449 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    533 rdf:type schema:MonetaryGrant
    534 sg:grant.5134440 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    535 rdf:type schema:MonetaryGrant
    536 sg:grant.5140177 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    537 rdf:type schema:MonetaryGrant
    538 sg:grant.5141446 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    539 rdf:type schema:MonetaryGrant
    540 sg:grant.5143008 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    541 rdf:type schema:MonetaryGrant
    542 sg:grant.5475480 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    543 rdf:type schema:MonetaryGrant
    544 sg:grant.6443219 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    545 rdf:type schema:MonetaryGrant
    546 sg:grant.6445883 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    547 rdf:type schema:MonetaryGrant
    548 sg:grant.6944894 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    549 rdf:type schema:MonetaryGrant
    550 sg:grant.7028443 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-02662-2
    551 rdf:type schema:MonetaryGrant
    552 sg:journal.1043282 schema:issn 2041-1723
    553 schema:name Nature Communications
    554 rdf:type schema:Periodical
    555 sg:person.01003275415.57 schema:affiliation https://www.grid.ac/institutes/grid.8993.b
    556 schema:familyName Lind
    557 schema:givenName Lars
    558 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01003275415.57
    559 rdf:type schema:Person
    560 sg:person.01003710361.37 schema:affiliation https://www.grid.ac/institutes/grid.66859.34
    561 schema:familyName Kiel
    562 schema:givenName Douglas P.
    563 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01003710361.37
    564 rdf:type schema:Person
    565 sg:person.010047240537.27 schema:affiliation https://www.grid.ac/institutes/grid.4818.5
    566 schema:familyName de Groot
    567 schema:givenName Lisette C. P. G. M.
    568 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010047240537.27
    569 rdf:type schema:Person
    570 sg:person.01006015331.07 schema:affiliation https://www.grid.ac/institutes/grid.420086.8
    571 schema:familyName Weinstein
    572 schema:givenName Stephanie J.
    573 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01006015331.07
    574 rdf:type schema:Person
    575 sg:person.01015660301.22 schema:affiliation https://www.grid.ac/institutes/grid.5335.0
    576 schema:familyName Sofianopoulou
    577 schema:givenName Eleni
    578 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015660301.22
    579 rdf:type schema:Person
    580 sg:person.01020276562.45 schema:affiliation https://www.grid.ac/institutes/grid.5509.9
    581 schema:familyName Lyytikäinen
    582 schema:givenName Leo-Pekka
    583 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020276562.45
    584 rdf:type schema:Person
    585 sg:person.01024575002.28 schema:affiliation https://www.grid.ac/institutes/grid.420086.8
    586 schema:familyName Albanes
    587 schema:givenName Demetrius
    588 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01024575002.28
    589 rdf:type schema:Person
    590 sg:person.01031064300.74 schema:affiliation https://www.grid.ac/institutes/grid.8761.8
    591 schema:familyName Ohlsson
    592 schema:givenName Claes
    593 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031064300.74
    594 rdf:type schema:Person
    595 sg:person.01060172311.14 schema:affiliation https://www.grid.ac/institutes/grid.4305.2
    596 schema:familyName Wilson
    597 schema:givenName James F.
    598 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060172311.14
    599 rdf:type schema:Person
    600 sg:person.01061362614.78 schema:affiliation https://www.grid.ac/institutes/grid.7737.4
    601 schema:familyName Tikkanen
    602 schema:givenName Emmi
    603 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01061362614.78
    604 rdf:type schema:Person
    605 sg:person.01065702313.98 schema:affiliation https://www.grid.ac/institutes/grid.463419.d
    606 schema:familyName Wood
    607 schema:givenName Alexis C.
    608 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01065702313.98
    609 rdf:type schema:Person
    610 sg:person.01066607126.16 schema:affiliation https://www.grid.ac/institutes/grid.428999.7
    611 schema:familyName Aschard
    612 schema:givenName Hugues
    613 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01066607126.16
    614 rdf:type schema:Person
    615 sg:person.01104262534.26 schema:affiliation https://www.grid.ac/institutes/grid.267308.8
    616 schema:familyName Boerwinkle
    617 schema:givenName Eric
    618 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01104262534.26
    619 rdf:type schema:Person
    620 sg:person.01114232756.11 schema:affiliation https://www.grid.ac/institutes/grid.8217.c
    621 schema:familyName Zgaga
    622 schema:givenName Lina
    623 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114232756.11
    624 rdf:type schema:Person
    625 sg:person.01114645561.56 schema:affiliation https://www.grid.ac/institutes/grid.420086.8
    626 schema:familyName Freedman
    627 schema:givenName Neal D.
    628 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114645561.56
    629 rdf:type schema:Person
    630 sg:person.011173242767.55 schema:affiliation https://www.grid.ac/institutes/grid.4305.2
    631 schema:familyName Theodoratou
    632 schema:givenName Evropi
    633 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011173242767.55
    634 rdf:type schema:Person
    635 sg:person.01131101310.00 schema:affiliation https://www.grid.ac/institutes/grid.4868.2
    636 schema:familyName Cavadino
    637 schema:givenName Alana
    638 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01131101310.00
    639 rdf:type schema:Person
    640 sg:person.01132715706.47 schema:affiliation https://www.grid.ac/institutes/grid.5335.0
    641 schema:familyName Butterworth
    642 schema:givenName Adam S.
    643 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01132715706.47
    644 rdf:type schema:Person
    645 sg:person.01145654113.82 schema:affiliation https://www.grid.ac/institutes/grid.8993.b
    646 schema:familyName Ingelsson
    647 schema:givenName Erik
    648 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145654113.82
    649 rdf:type schema:Person
    650 sg:person.01150747020.74 schema:affiliation https://www.grid.ac/institutes/grid.439075.c
    651 schema:familyName Gundersen
    652 schema:givenName Thomas E.
    653 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150747020.74
    654 rdf:type schema:Person
    655 sg:person.011673465237.05 schema:affiliation https://www.grid.ac/institutes/grid.4567.0
    656 schema:familyName Gieger
    657 schema:givenName Christian
    658 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011673465237.05
    659 rdf:type schema:Person
    660 sg:person.011741202517.08 schema:affiliation https://www.grid.ac/institutes/grid.17635.36
    661 schema:familyName Lutsey
    662 schema:givenName Pamela L.
    663 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011741202517.08
    664 rdf:type schema:Person
    665 sg:person.01200771067.24 schema:affiliation https://www.grid.ac/institutes/grid.11598.34
    666 schema:familyName März
    667 schema:givenName Winfried
    668 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01200771067.24
    669 rdf:type schema:Person
    670 sg:person.012142217732.11 schema:affiliation N4a11395674ca44499e352034e3c15ab1
    671 schema:familyName Farrington
    672 schema:givenName Susan M.
    673 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012142217732.11
    674 rdf:type schema:Person
    675 sg:person.012213174274.48 schema:affiliation https://www.grid.ac/institutes/grid.420086.8
    676 schema:familyName Huang
    677 schema:givenName Wen-Yi
    678 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012213174274.48
    679 rdf:type schema:Person
    680 sg:person.012264440652.05 schema:affiliation https://www.grid.ac/institutes/grid.239844.0
    681 schema:familyName Rotter
    682 schema:givenName Jerome I.
    683 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012264440652.05
    684 rdf:type schema:Person
    685 sg:person.01230220117.55 schema:affiliation https://www.grid.ac/institutes/grid.189504.1
    686 schema:familyName Dupuis
    687 schema:givenName Josée
    688 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01230220117.55
    689 rdf:type schema:Person
    690 sg:person.01236775365.34 schema:affiliation https://www.grid.ac/institutes/grid.5650.6
    691 schema:familyName van der Velde
    692 schema:givenName Nathalie
    693 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01236775365.34
    694 rdf:type schema:Person
    695 sg:person.01242715665.45 schema:affiliation https://www.grid.ac/institutes/grid.7737.4
    696 schema:familyName Eriksson
    697 schema:givenName Johan G.
    698 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01242715665.45
    699 rdf:type schema:Person
    700 sg:person.01247550615.12 schema:affiliation https://www.grid.ac/institutes/grid.10419.3d
    701 schema:familyName Slagboom
    702 schema:givenName Eline
    703 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01247550615.12
    704 rdf:type schema:Person
    705 sg:person.01261451553.16 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    706 schema:familyName Michos
    707 schema:givenName Erin D.
    708 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261451553.16
    709 rdf:type schema:Person
    710 sg:person.01262170300.25 schema:affiliation https://www.grid.ac/institutes/grid.4305.2
    711 schema:familyName Campbell
    712 schema:givenName Harry
    713 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01262170300.25
    714 rdf:type schema:Person
    715 sg:person.01267360065.55 schema:affiliation https://www.grid.ac/institutes/grid.1374.1
    716 schema:familyName Raitakari
    717 schema:givenName Olli T.
    718 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01267360065.55
    719 rdf:type schema:Person
    720 sg:person.01306434164.83 schema:affiliation https://www.grid.ac/institutes/grid.4714.6
    721 schema:familyName Jiang
    722 schema:givenName Xia
    723 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01306434164.83
    724 rdf:type schema:Person
    725 sg:person.01313052166.05 schema:affiliation Nbd16214a00a84e96968c7fdc30a08b7e
    726 schema:familyName Vasan
    727 schema:givenName Ramachandran S.
    728 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313052166.05
    729 rdf:type schema:Person
    730 sg:person.013165261347.40 schema:affiliation https://www.grid.ac/institutes/grid.412807.8
    731 schema:familyName Robinson-Cohen
    732 schema:givenName Cassianne
    733 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013165261347.40
    734 rdf:type schema:Person
    735 sg:person.01317660746.45 schema:affiliation https://www.grid.ac/institutes/grid.1026.5
    736 schema:familyName Hyppönen
    737 schema:givenName Elina
    738 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317660746.45
    739 rdf:type schema:Person
    740 sg:person.01326573405.52 schema:affiliation https://www.grid.ac/institutes/grid.257413.6
    741 schema:familyName Peacock
    742 schema:givenName Munro
    743 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01326573405.52
    744 rdf:type schema:Person
    745 sg:person.01327765331.73 schema:affiliation https://www.grid.ac/institutes/grid.66859.34
    746 schema:familyName Hsu
    747 schema:givenName Yi-Hsiang
    748 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01327765331.73
    749 rdf:type schema:Person
    750 sg:person.01330734403.13 schema:affiliation https://www.grid.ac/institutes/grid.419502.b
    751 schema:familyName Deelen
    752 schema:givenName Joris
    753 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01330734403.13
    754 rdf:type schema:Person
    755 sg:person.01335473265.62 schema:affiliation https://www.grid.ac/institutes/grid.5509.9
    756 schema:familyName Kähönen
    757 schema:givenName Mika
    758 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335473265.62
    759 rdf:type schema:Person
    760 sg:person.01341032053.15 schema:affiliation https://www.grid.ac/institutes/grid.7700.0
    761 schema:familyName Kleber
    762 schema:givenName Marcus E.
    763 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341032053.15
    764 rdf:type schema:Person
    765 sg:person.01353111051.81 schema:affiliation https://www.grid.ac/institutes/grid.10419.3d
    766 schema:familyName van Heemst
    767 schema:givenName Diana
    768 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01353111051.81
    769 rdf:type schema:Person
    770 sg:person.01356554174.39 schema:affiliation https://www.grid.ac/institutes/grid.16872.3a
    771 schema:familyName Van Schoor
    772 schema:givenName Natasja M.
    773 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356554174.39
    774 rdf:type schema:Person
    775 sg:person.01365531352.22 schema:affiliation https://www.grid.ac/institutes/grid.189504.1
    776 schema:familyName Cupples
    777 schema:givenName L. Adrienne
    778 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365531352.22
    779 rdf:type schema:Person
    780 sg:person.01367711150.31 schema:affiliation https://www.grid.ac/institutes/grid.10306.34
    781 schema:familyName Danesh
    782 schema:givenName John
    783 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01367711150.31
    784 rdf:type schema:Person
    785 sg:person.013723776517.34 schema:affiliation https://www.grid.ac/institutes/grid.5335.0
    786 schema:familyName Wareham
    787 schema:givenName Nicholas J.
    788 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013723776517.34
    789 rdf:type schema:Person
    790 sg:person.014511602440.06 schema:affiliation https://www.grid.ac/institutes/grid.1026.5
    791 schema:familyName Zhou
    792 schema:givenName Ang
    793 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014511602440.06
    794 rdf:type schema:Person
    795 sg:person.015301404517.88 schema:affiliation https://www.grid.ac/institutes/grid.412326.0
    796 schema:familyName Jarvelin
    797 schema:givenName Marjo-Riitta
    798 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015301404517.88
    799 rdf:type schema:Person
    800 sg:person.015356157217.08 schema:affiliation https://www.grid.ac/institutes/grid.419475.a
    801 schema:familyName Ferrucci
    802 schema:givenName Luigi
    803 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015356157217.08
    804 rdf:type schema:Person
    805 sg:person.015521617657.37 schema:affiliation https://www.grid.ac/institutes/grid.5335.0
    806 schema:familyName Khaw
    807 schema:givenName Kay-Tee
    808 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015521617657.37
    809 rdf:type schema:Person
    810 sg:person.015565463537.09 schema:affiliation https://www.grid.ac/institutes/grid.27755.32
    811 schema:familyName Rich
    812 schema:givenName Stephen S.
    813 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015565463537.09
    814 rdf:type schema:Person
    815 sg:person.015732055741.64 schema:affiliation https://www.grid.ac/institutes/grid.5645.2
    816 schema:familyName Heijer
    817 schema:givenName Martin den
    818 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015732055741.64
    819 rdf:type schema:Person
    820 sg:person.016403337057.14 schema:affiliation N8e5bc378c6174eefb0a4d853404db811
    821 schema:familyName Kritchevsky
    822 schema:givenName Stephen B.
    823 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016403337057.14
    824 rdf:type schema:Person
    825 sg:person.016674701102.75 schema:affiliation https://www.grid.ac/institutes/grid.10419.3d
    826 schema:familyName Jukema
    827 schema:givenName J. Wouter
    828 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016674701102.75
    829 rdf:type schema:Person
    830 sg:person.016704245502.43 schema:affiliation https://www.grid.ac/institutes/grid.415719.f
    831 schema:familyName McCarthy
    832 schema:givenName Mark I.
    833 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016704245502.43
    834 rdf:type schema:Person
    835 sg:person.0604632732.94 schema:affiliation https://www.grid.ac/institutes/grid.411024.2
    836 schema:familyName Streeten
    837 schema:givenName Elizabeth A.
    838 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604632732.94
    839 rdf:type schema:Person
    840 sg:person.0616003437.07 schema:affiliation https://www.grid.ac/institutes/grid.5335.0
    841 schema:familyName Langenberg
    842 schema:givenName Claudia
    843 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0616003437.07
    844 rdf:type schema:Person
    845 sg:person.0621621022.09 schema:affiliation https://www.grid.ac/institutes/grid.5335.0
    846 schema:familyName Forouhi
    847 schema:givenName Nita G.
    848 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0621621022.09
    849 rdf:type schema:Person
    850 sg:person.0654341265.88 schema:affiliation https://www.grid.ac/institutes/grid.5509.9
    851 schema:familyName Lehtimäki
    852 schema:givenName Terho
    853 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0654341265.88
    854 rdf:type schema:Person
    855 sg:person.0657304603.00 schema:affiliation https://www.grid.ac/institutes/grid.10419.3d
    856 schema:familyName Beekman
    857 schema:givenName Marian
    858 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657304603.00
    859 rdf:type schema:Person
    860 sg:person.0664341505.44 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
    861 schema:familyName O’Reilly
    862 schema:givenName Paul F.
    863 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0664341505.44
    864 rdf:type schema:Person
    865 sg:person.0701147373.33 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
    866 schema:familyName Valdes
    867 schema:givenName Ana M.
    868 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0701147373.33
    869 rdf:type schema:Person
    870 sg:person.0712400456.14 schema:affiliation https://www.grid.ac/institutes/grid.5603.0
    871 schema:familyName Völzke
    872 schema:givenName Henry
    873 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0712400456.14
    874 rdf:type schema:Person
    875 sg:person.0712704164.77 schema:affiliation https://www.grid.ac/institutes/grid.429997.8
    876 schema:familyName Shea
    877 schema:givenName M. Kyla
    878 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0712704164.77
    879 rdf:type schema:Person
    880 sg:person.0721676562.69 schema:affiliation https://www.grid.ac/institutes/grid.257413.6
    881 schema:familyName Econs
    882 schema:givenName Michael J.
    883 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721676562.69
    884 rdf:type schema:Person
    885 sg:person.0724034436.28 schema:affiliation https://www.grid.ac/institutes/grid.8993.b
    886 schema:familyName Michaëlsson
    887 schema:givenName Karl
    888 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0724034436.28
    889 rdf:type schema:Person
    890 sg:person.0727423345.30 schema:affiliation https://www.grid.ac/institutes/grid.8761.8
    891 schema:familyName Vandenput
    892 schema:givenName Liesbeth
    893 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0727423345.30
    894 rdf:type schema:Person
    895 sg:person.0747376474.29 schema:affiliation https://www.grid.ac/institutes/grid.5645.2
    896 schema:familyName Enneman
    897 schema:givenName Anke
    898 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0747376474.29
    899 rdf:type schema:Person
    900 sg:person.07512454234.04 schema:affiliation https://www.grid.ac/institutes/grid.38142.3c
    901 schema:familyName Kraft
    902 schema:givenName Peter
    903 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07512454234.04
    904 rdf:type schema:Person
    905 sg:person.0751717266.10 schema:affiliation https://www.grid.ac/institutes/grid.11598.34
    906 schema:familyName Pilz
    907 schema:givenName Stefan
    908 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0751717266.10
    909 rdf:type schema:Person
    910 sg:person.0754621150.33 schema:affiliation https://www.grid.ac/institutes/grid.452396.f
    911 schema:familyName Wallaschofski
    912 schema:givenName Henri
    913 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0754621150.33
    914 rdf:type schema:Person
    915 sg:person.0763100407.41 schema:affiliation https://www.grid.ac/institutes/grid.4305.2
    916 schema:familyName Joshi
    917 schema:givenName Peter K.
    918 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0763100407.41
    919 rdf:type schema:Person
    920 sg:person.0766720170.34 schema:affiliation N41685d4511834087b2799746c7c0a373
    921 schema:familyName Lohman
    922 schema:givenName Kurt K.
    923 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0766720170.34
    924 rdf:type schema:Person
    925 sg:person.0776707354.45 schema:affiliation https://www.grid.ac/institutes/grid.5335.0
    926 schema:familyName Luan
    927 schema:givenName Jianan
    928 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0776707354.45
    929 rdf:type schema:Person
    930 sg:pub.10.1007/s12016-012-8342-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1035787415
    931 https://doi.org/10.1007/s12016-012-8342-y
    932 rdf:type schema:CreativeWork
    933 sg:pub.10.1007/s12016-013-8361-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011043576
    934 https://doi.org/10.1007/s12016-013-8361-3
    935 rdf:type schema:CreativeWork
    936 sg:pub.10.1007/s12253-010-9322-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002075029
    937 https://doi.org/10.1007/s12253-010-9322-2
    938 rdf:type schema:CreativeWork
    939 sg:pub.10.1038/mp.2013.187 schema:sameAs