Predictors of responses to immune checkpoint blockade in advanced melanoma View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-12

AUTHORS

N. Jacquelot, M. P. Roberti, D. P. Enot, S. Rusakiewicz, N. Ternès, S. Jegou, D. M. Woods, A. L. Sodré, M. Hansen, Y. Meirow, M. Sade-Feldman, A. Burra, S. S. Kwek, C. Flament, M. Messaoudene, C. P. M. Duong, L. Chen, B. S. Kwon, A. C. Anderson, V. K. Kuchroo, B. Weide, F. Aubin, C. Borg, S. Dalle, O. Beatrix, M. Ayyoub, B. Balme, G. Tomasic, A. M. Di Giacomo, M. Maio, D. Schadendorf, I. Melero, B. Dréno, A. Khammari, R. Dummer, M. Levesque, Y. Koguchi, L. Fong, M. Lotem, M. Baniyash, H. Schmidt, I. M. Svane, G. Kroemer, A. Marabelle, S. Michiels, A. Cavalcanti, M. J. Smyth, J. S. Weber, A. M. Eggermont, L. Zitvogel

ABSTRACT

Immune checkpoint blockers (ICB) have become pivotal therapies in the clinical armamentarium against metastatic melanoma (MMel). Given the frequency of immune related adverse events and increasing use of ICB, predictors of response to CTLA-4 and/or PD-1 blockade represent unmet clinical needs. Using a systems biology-based approach to an assessment of 779 paired blood and tumor markers in 37 stage III MMel patients, we analyzed association between blood immune parameters and the functional immune reactivity of tumor-infiltrating cells after ex vivo exposure to ICB. Based on this assay, we retrospectively observed, in eight cohorts enrolling 190 MMel patients treated with ipilimumab, that PD-L1 expression on peripheral T cells was prognostic on overall and progression-free survival. Moreover, detectable CD137 on circulating CD8+ T cells was associated with the disease-free status of resected stage III MMel patients after adjuvant ipilimumab + nivolumab (but not nivolumab alone). These biomarkers should be validated in prospective trials in MMel.The clinical management of metastatic melanoma requires predictors of the response to checkpoint blockade. Here, the authors use immunological assays to identify potential prognostic/predictive biomarkers in circulating blood cells and in tumor-infiltrating lymphocytes from patients with resected stage III melanoma. More... »

PAGES

592

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41467-017-00608-2

DOI

http://dx.doi.org/10.1038/s41467-017-00608-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1091688617

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28928380


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Immunology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "INSERM U1015, Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "University Paris-Saclay, 94 276, Kremlin Bic\u00eatre, France", 
            "Gustave Roussy Cancer Campus, 94800, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jacquelot", 
        "givenName": "N.", 
        "id": "sg:person.01170777250.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170777250.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "INSERM U1015, Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "Gustave Roussy Cancer Campus, 94800, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Roberti", 
        "givenName": "M. P.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, 94800, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Enot", 
        "givenName": "D. P.", 
        "id": "sg:person.01341501713.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341501713.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "INSERM U1015, Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "CIC1428, Gustave Roussy Cancer Campus, 94800, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rusakiewicz", 
        "givenName": "S.", 
        "id": "sg:person.0657152274.85", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657152274.85"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "University Paris-Saclay, 94 276, Kremlin Bic\u00eatre, France", 
            "Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "Gustave Roussy, Universit\u00e9 Paris-Saclay, Service de Biostatistique et d\u2019Epid\u00e9miologie, F-94805, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tern\u00e8s", 
        "givenName": "N.", 
        "id": "sg:person.0770276230.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0770276230.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Saint-Antoine", 
          "id": "https://www.grid.ac/institutes/grid.412370.3", 
          "name": [
            "Saint Antoine Hospital, INSERM ERL 1157-CNRS UMR 7203, 75005, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jegou", 
        "givenName": "S.", 
        "id": "sg:person.01005217353.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01005217353.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "New York University Langone Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.240324.3", 
          "name": [
            "Laura & Isaac Perlmutter Cancer Center, New York University Medical Center, 10016, New York, NY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Woods", 
        "givenName": "D. M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "New York University Langone Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.240324.3", 
          "name": [
            "Laura & Isaac Perlmutter Cancer Center, New York University Medical Center, 10016, New York, NY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sodr\u00e9", 
        "givenName": "A. L.", 
        "id": "sg:person.0622221332.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622221332.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Herlev Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411900.d", 
          "name": [
            "Center for Cancer Immune Therapy, Department of Hematology and Oncology, Copenhagen University Hospital, DK-2730, Herlev, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hansen", 
        "givenName": "M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hebrew University of Jerusalem", 
          "id": "https://www.grid.ac/institutes/grid.9619.7", 
          "name": [
            "The Lautenberg Center for General and Tumor Immunology, BioMedical Research institute Israel Canada of the Faculty of Medicine, The Hebrew University Hadassah Medical School, 91120, Jerusalem, Israel"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Meirow", 
        "givenName": "Y.", 
        "id": "sg:person.0754740703.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0754740703.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hebrew University of Jerusalem", 
          "id": "https://www.grid.ac/institutes/grid.9619.7", 
          "name": [
            "The Lautenberg Center for General and Tumor Immunology, BioMedical Research institute Israel Canada of the Faculty of Medicine, The Hebrew University Hadassah Medical School, 91120, Jerusalem, Israel"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sade-Feldman", 
        "givenName": "M.", 
        "id": "sg:person.01160336661.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01160336661.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California, San Francisco", 
          "id": "https://www.grid.ac/institutes/grid.266102.1", 
          "name": [
            "Division of Hematology/Oncology, Department of Medicine, University of California, 94143, San Francisco, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Burra", 
        "givenName": "A.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California, San Francisco", 
          "id": "https://www.grid.ac/institutes/grid.266102.1", 
          "name": [
            "Division of Hematology/Oncology, Department of Medicine, University of California, 94143, San Francisco, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kwek", 
        "givenName": "S. S.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "INSERM U1015, Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "University Paris-Saclay, 94 276, Kremlin Bic\u00eatre, France", 
            "Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "CIC1428, Gustave Roussy Cancer Campus, 94800, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Flament", 
        "givenName": "C.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "INSERM U1015, Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "Gustave Roussy Cancer Campus, 94800, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Messaoudene", 
        "givenName": "M.", 
        "id": "sg:person.01012276550.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012276550.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "INSERM U1015, Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "Gustave Roussy Cancer Campus, 94800, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Duong", 
        "givenName": "C. P. M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Yale University", 
          "id": "https://www.grid.ac/institutes/grid.47100.32", 
          "name": [
            "Department of Immunobiology, Yale School of Medicine, 10 Amistad Street, 06519, New Haven, CT, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chen", 
        "givenName": "L.", 
        "id": "sg:person.016303325577.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016303325577.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tulane University", 
          "id": "https://www.grid.ac/institutes/grid.265219.b", 
          "name": [
            "Eutilex, Suite# 1401 Daeryung Technotown 17 Gasan Digital 1-ro 25, 08594, Geumcheon-gu, Seoul, Korea", 
            "Section of Clinical Immunology, Allergy, and Rheumatology, Department of Medicine, Tulane University Health Sciences Center, 70112, New Orleans, LA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kwon", 
        "givenName": "B. S.", 
        "id": "sg:person.015361211617.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015361211617.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Harvard University", 
          "id": "https://www.grid.ac/institutes/grid.38142.3c", 
          "name": [
            "Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Brigham and Women\u2019s Hospital and Harvard Medical School, 02115, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Anderson", 
        "givenName": "A. C.", 
        "id": "sg:person.0676714763.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0676714763.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Harvard University", 
          "id": "https://www.grid.ac/institutes/grid.38142.3c", 
          "name": [
            "Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Brigham and Women\u2019s Hospital and Harvard Medical School, 02115, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kuchroo", 
        "givenName": "V. K.", 
        "id": "sg:person.0700425476.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700425476.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Universit\u00e4tsklinikum T\u00fcbingen", 
          "id": "https://www.grid.ac/institutes/grid.411544.1", 
          "name": [
            "Department of Dermatology, University Medical Center T\u00fcbingen, 72076, T\u00fcbingen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Weide", 
        "givenName": "B.", 
        "id": "sg:person.01314673254.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01314673254.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Universit\u00e9 de Franche Comt\u00e9, EA3181, SFR4234, Service de Dermatologie, Centre Hospitalier Universitaire (CHU), 25000, Besan\u00e7on, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Aubin", 
        "givenName": "F.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Franche-Comt\u00e9", 
          "id": "https://www.grid.ac/institutes/grid.7459.f", 
          "name": [
            "Department of Medical Oncology, University Hospital of Besancon, 3 Boulevard Alexander Fleming, F-25030, Besancon, France", 
            "Clinical Investigational Centre, CIC-1431, University Hospital of Besan\u00e7on, 25030, Besan\u00e7on, France", 
            "INSERM U1098, University of Franche-Comt\u00e9, 25020, Besan\u00e7on, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Borg", 
        "givenName": "C.", 
        "id": "sg:person.01153060003.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01153060003.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cancer Center of Lyon", 
          "id": "https://www.grid.ac/institutes/grid.462282.8", 
          "name": [
            "Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon and University Claude Bernard Lyon 1, 69000, Lyon, France", 
            "Centre de Recherche en Canc\u00e9rologie de Lyon, 69000, Lyon, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dalle", 
        "givenName": "S.", 
        "id": "sg:person.01060723265.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060723265.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Lyon Sud", 
          "id": "https://www.grid.ac/institutes/grid.411430.3", 
          "name": [
            "Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon and University Claude Bernard Lyon 1, 69000, Lyon, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Beatrix", 
        "givenName": "O.", 
        "id": "sg:person.01054702726.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054702726.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "INSERM U1015, Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "Gustave Roussy Cancer Campus, 94800, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ayyoub", 
        "givenName": "M.", 
        "id": "sg:person.01322650310.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01322650310.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospices Civils de Lyon", 
          "id": "https://www.grid.ac/institutes/grid.413852.9", 
          "name": [
            "Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon and University Claude Bernard Lyon 1, 69000, Lyon, France", 
            "Department of Pathology, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, 69000, Lyon, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Balme", 
        "givenName": "B.", 
        "id": "sg:person.01323064306.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01323064306.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "Department of Pathology, Gustave Roussy Cancer Campus, 94800, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tomasic", 
        "givenName": "G.", 
        "id": "sg:person.0665460265.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0665460265.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Azienda Ospedaliera Universitaria Senese", 
          "id": "https://www.grid.ac/institutes/grid.411477.0", 
          "name": [
            "Medical Oncology and Immunotherapy Division, University Hospital of Siena, Viale Bracci, 14, 53100, Siena, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Di Giacomo", 
        "givenName": "A. M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Azienda Ospedaliera Universitaria Senese", 
          "id": "https://www.grid.ac/institutes/grid.411477.0", 
          "name": [
            "Medical Oncology and Immunotherapy, Department of Oncology, University Hospital of Siena, Instituto Toscano Tumori, 53100, Siena, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maio", 
        "givenName": "M.", 
        "id": "sg:person.01061427172.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01061427172.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Duisburg-Essen", 
          "id": "https://www.grid.ac/institutes/grid.5718.b", 
          "name": [
            "Department of Dermatology, University Hospital, University Duisburg-Essen, Essen, Germany & German Cancer Consortium (DKTZ), D-69120, Heidelberg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schadendorf", 
        "givenName": "D.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Clinica Universidad de Navarra", 
          "id": "https://www.grid.ac/institutes/grid.411730.0", 
          "name": [
            "Division of Gene Therapy and Hepatology, Centre for Applied Medical Research, 31008, Pamplona, Spain", 
            "Oncology Department, University Clinic of Navarra, 31008, Pamplona, Spain", 
            "Centro de Investigaci\u00f3n cBiomedica en Red de Oncologia, 31008, Pamplona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Melero", 
        "givenName": "I.", 
        "id": "sg:person.0777142412.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0777142412.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Nantes", 
          "id": "https://www.grid.ac/institutes/grid.277151.7", 
          "name": [
            "Department of Onco-dermatology, CIC Biotherapy, INSERM U1232, CHU Nantes, 44000, Nantes, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dr\u00e9no", 
        "givenName": "B.", 
        "id": "sg:person.01146563400.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01146563400.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Nantes", 
          "id": "https://www.grid.ac/institutes/grid.277151.7", 
          "name": [
            "Department of Onco-dermatology, CIC Biotherapy, INSERM U1232, CHU Nantes, 44000, Nantes, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Khammari", 
        "givenName": "A.", 
        "id": "sg:person.0717176144.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717176144.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Dermatology, University Hospital Z\u00fcrich and University of Z\u00fcrich, 8091, Z\u00fcrich, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dummer", 
        "givenName": "R.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Dermatology, University Hospital Z\u00fcrich and University of Z\u00fcrich, 8091, Z\u00fcrich, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Levesque", 
        "givenName": "M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Providence St. Vincent Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.415337.7", 
          "name": [
            "Earle A. Chiles Research Institute, Providence Cancer Center, 97213, Portland, OR, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Koguchi", 
        "givenName": "Y.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California, San Francisco", 
          "id": "https://www.grid.ac/institutes/grid.266102.1", 
          "name": [
            "Division of Hematology/Oncology, Department of Medicine, University of California, 94143, San Francisco, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fong", 
        "givenName": "L.", 
        "id": "sg:person.011243423402.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011243423402.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hadassah Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.17788.31", 
          "name": [
            "Sharett Institute of Oncology, Hadassah Medical Organization, 91120, Jerusalem, Israel"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lotem", 
        "givenName": "M.", 
        "id": "sg:person.01062103030.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062103030.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hebrew University of Jerusalem", 
          "id": "https://www.grid.ac/institutes/grid.9619.7", 
          "name": [
            "The Lautenberg Center for General and Tumor Immunology, BioMedical Research institute Israel Canada of the Faculty of Medicine, The Hebrew University Hadassah Medical School, 91120, Jerusalem, Israel"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Baniyash", 
        "givenName": "M.", 
        "id": "sg:person.01006244063.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01006244063.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Aarhus University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.154185.c", 
          "name": [
            "Department of Oncology, Aarhus University Hospital, DK-8200, Aarhus, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schmidt", 
        "givenName": "H.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Herlev Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411900.d", 
          "name": [
            "Center for Cancer Immune Therapy, Department of Hematology and Oncology, Copenhagen University Hospital, DK-2730, Herlev, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Svane", 
        "givenName": "I. M.", 
        "id": "sg:person.0635206541.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0635206541.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Europ\u00e9en Georges-Pompidou", 
          "id": "https://www.grid.ac/institutes/grid.414093.b", 
          "name": [
            "Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "INSERM U1138, Centre de Recherche des Cordeliers, 75006, Paris, France", 
            "Equipe 11 labellis\u00e9e par la Ligue contre le Cancer, Centre de Recherche des Cordeliers, 75006, Paris, France", 
            "Universit\u00e9 Paris Descartes, Sorbonne Paris Cit\u00e9, 75006, Paris, France", 
            "Universit\u00e9 Pierre et Marie Curie, 75005, Paris, France", 
            "P\u00f4le de Biologie, H\u00f4pital Europ\u00e9en Georges Pompidou, AP-HP, 75015, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kroemer", 
        "givenName": "G.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "INSERM U1015, Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "CIC1428, Gustave Roussy Cancer Campus, 94800, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Marabelle", 
        "givenName": "A.", 
        "id": "sg:person.0746230417.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0746230417.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "Gustave Roussy, Universit\u00e9 Paris-Saclay, Service de Biostatistique et d\u2019Epid\u00e9miologie, F-94805, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Michiels", 
        "givenName": "S.", 
        "id": "sg:person.01020424360.96", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020424360.96"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "Department of Surgery, Gustave Roussy Cancer Center, 94800, Villejuif, France", 
            "Department of Dermatology, Gustave Roussy Cancer Center, 94800, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cavalcanti", 
        "givenName": "A.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Queensland", 
          "id": "https://www.grid.ac/institutes/grid.1003.2", 
          "name": [
            "Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, 4006, Herston, QLD, Australia", 
            "School of Medicine, University of Queensland, 4006, Herston, QLD, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Smyth", 
        "givenName": "M. J.", 
        "id": "sg:person.01010600434.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01010600434.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "New York University Langone Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.240324.3", 
          "name": [
            "Laura & Isaac Perlmutter Cancer Center, New York University Medical Center, 10016, New York, NY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Weber", 
        "givenName": "J. S.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "Gustave Roussy Cancer Campus, 94800, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Eggermont", 
        "givenName": "A. M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Gustave Roussy", 
          "id": "https://www.grid.ac/institutes/grid.14925.3b", 
          "name": [
            "INSERM U1015, Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "University Paris-Saclay, 94 276, Kremlin Bic\u00eatre, France", 
            "Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "CIC1428, Gustave Roussy Cancer Campus, 94800, Villejuif, France", 
            "Gustave Roussy, Universit\u00e9 Paris-Saclay, Service de Biostatistique et d\u2019Epid\u00e9miologie, F-94805, Villejuif, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zitvogel", 
        "givenName": "L.", 
        "id": "sg:person.01214767546.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01214767546.51"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/s1470-2045(16)30366-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001468571"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1479-5876-9-204", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002969174", 
          "https://doi.org/10.1186/1479-5876-9-204"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.molonc.2015.10.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003821098"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1470-2045(15)70122-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003860539"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12253-008-9109-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004056254", 
          "https://doi.org/10.1007/s12253-008-9109-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2014.58.1967", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006980479"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1414428", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007696832"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-15-2303", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008301360"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-15-2412", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008399758"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jid.2015.12.042", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008425988"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/cr.2015.3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008573304", 
          "https://doi.org/10.1038/cr.2015.3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdt027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008750772"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2016.11.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009220256"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2016.11.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009220256"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00262-011-1172-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009295521", 
          "https://doi.org/10.1007/s00262-011-1172-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.21264", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012911980"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.21264", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012911980"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-2133.2002.04745.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014774895"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1001294", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017807249"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.24951", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018207285"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.24951", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018207285"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/scitranslmed.3003689", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018365419"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci81217", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018400866"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00268-002-6378-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018719615", 
          "https://doi.org/10.1007/s00268-002-6378-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/2326-6066.cir-13-0020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019042882"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1406498", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020435459"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature13954", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020455470", 
          "https://doi.org/10.1038/nature13954"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1611299", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020609326"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1611299", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020609326"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1611299", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020609326"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2009.26.7609", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020897568"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/scitranslmed.3003634", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020921605"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.seminoncol.2015.02.016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021039257"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature12213", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021761707", 
          "https://doi.org/10.1038/nature12213"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/2326-6066.cir-14-0013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021999618"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1189/jlb.2mr0215-055r", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022591957"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2015.08.052", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024088208"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s2213-2600(13)70159-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024358603"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdt161", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024839180"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1504030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024843336"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-14-3128", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025700448"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-14-3253", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025801974"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrclinonc.2015.106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026995724", 
          "https://doi.org/10.1038/nrclinonc.2015.106"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0084927", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028199095"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-09-1624", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028571226"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci80071", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029324712"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/2326-6066.cir-15-0193", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029683691"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1501824", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031881319"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2015.03.045", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033378425"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1479-5876-3-10", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033807595", 
          "https://doi.org/10.1186/1479-5876-3-10"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1470-2045(16)30624-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034482273"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.celrep.2015.08.077", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034973964"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/djq310", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037022855"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/his.12537", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037223091"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12253-012-9512-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037319234", 
          "https://doi.org/10.1007/s12253-012-9512-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm.3541", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039587457", 
          "https://doi.org/10.1038/nm.3541"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/02841860500482225", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040084577"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-13-2234", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040432582"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(13)60802-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043729077"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-15-0612", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045903927"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/scitranslmed.aaa3643", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046673496"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1200694", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047413837"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-13-1794", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049860235"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.3677", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052106779", 
          "https://doi.org/10.1038/ng.3677"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.seminoncol.2010.09.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052798261"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ccell.2015.03.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053023000"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/15548627.2015.1082022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058406596"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/2162402x.2015.1137418", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058420687"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/2162402x.2016.1235107", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058420771"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-15-3104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063225302"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-16-0127", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063225334"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074559855", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074813226", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078245726", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2016.34.15_suppl.9586", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1106842906"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-12", 
    "datePublishedReg": "2017-12-01", 
    "description": "Immune checkpoint blockers (ICB) have become pivotal therapies in the clinical armamentarium against metastatic melanoma (MMel). Given the frequency of immune related adverse events and increasing use of ICB, predictors of response to CTLA-4 and/or PD-1 blockade represent unmet clinical needs. Using a systems biology-based approach to an assessment of 779 paired blood and tumor markers in 37 stage III MMel patients, we analyzed association between blood immune parameters and the functional immune reactivity of tumor-infiltrating cells after ex vivo exposure to ICB. Based on this assay, we retrospectively observed, in eight cohorts enrolling 190 MMel patients treated with ipilimumab, that PD-L1 expression on peripheral T cells was prognostic on overall and progression-free survival. Moreover, detectable CD137 on circulating CD8+ T cells was associated with the disease-free status of resected stage III MMel patients after adjuvant ipilimumab\u2009+\u2009nivolumab (but not nivolumab alone). These biomarkers should be validated in prospective trials in MMel.The clinical management of metastatic melanoma requires predictors of the response to checkpoint blockade. Here, the authors use immunological assays to identify potential prognostic/predictive biomarkers in circulating blood cells and in tumor-infiltrating lymphocytes from patients with resected stage III melanoma.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/s41467-017-00608-2", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.3932694", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1043282", 
        "issn": [
          "2041-1723"
        ], 
        "name": "Nature Communications", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "8"
      }
    ], 
    "name": "Predictors of responses to immune checkpoint blockade in advanced melanoma", 
    "pagination": "592", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "233385b8aa09e68f674b428cbf66cc330e999386b29062ee74252abfe2b46c1d"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28928380"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101528555"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s41467-017-00608-2"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1091688617"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s41467-017-00608-2", 
      "https://app.dimensions.ai/details/publication/pub.1091688617"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T01:21", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8697_00000601.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/s41467-017-00608-2"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41467-017-00608-2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41467-017-00608-2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41467-017-00608-2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41467-017-00608-2'


 

This table displays all metadata directly associated to this object as RDF triples.

709 TRIPLES      21 PREDICATES      99 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s41467-017-00608-2 schema:about anzsrc-for:11
2 anzsrc-for:1107
3 schema:author N77cf586709cd44478d19262ba2274bf8
4 schema:citation sg:pub.10.1007/s00262-011-1172-6
5 sg:pub.10.1007/s00268-002-6378-5
6 sg:pub.10.1007/s12253-008-9109-x
7 sg:pub.10.1007/s12253-012-9512-1
8 sg:pub.10.1038/cr.2015.3
9 sg:pub.10.1038/nature12213
10 sg:pub.10.1038/nature13954
11 sg:pub.10.1038/ng.3677
12 sg:pub.10.1038/nm.3541
13 sg:pub.10.1038/nrclinonc.2015.106
14 sg:pub.10.1186/1479-5876-3-10
15 sg:pub.10.1186/1479-5876-9-204
16 https://app.dimensions.ai/details/publication/pub.1074559855
17 https://app.dimensions.ai/details/publication/pub.1074813226
18 https://app.dimensions.ai/details/publication/pub.1078245726
19 https://doi.org/10.1002/cncr.24951
20 https://doi.org/10.1002/ijc.21264
21 https://doi.org/10.1016/j.ccell.2015.03.001
22 https://doi.org/10.1016/j.cell.2015.03.045
23 https://doi.org/10.1016/j.cell.2015.08.052
24 https://doi.org/10.1016/j.cell.2016.11.022
25 https://doi.org/10.1016/j.celrep.2015.08.077
26 https://doi.org/10.1016/j.jid.2015.12.042
27 https://doi.org/10.1016/j.molonc.2015.10.009
28 https://doi.org/10.1016/s0140-6736(13)60802-8
29 https://doi.org/10.1016/s1470-2045(15)70122-1
30 https://doi.org/10.1016/s1470-2045(16)30366-7
31 https://doi.org/10.1016/s1470-2045(16)30624-6
32 https://doi.org/10.1016/s2213-2600(13)70159-0
33 https://doi.org/10.1046/j.1365-2133.2002.04745.x
34 https://doi.org/10.1053/j.seminoncol.2010.09.008
35 https://doi.org/10.1053/j.seminoncol.2015.02.016
36 https://doi.org/10.1056/nejmoa1001294
37 https://doi.org/10.1056/nejmoa1200694
38 https://doi.org/10.1056/nejmoa1406498
39 https://doi.org/10.1056/nejmoa1414428
40 https://doi.org/10.1056/nejmoa1501824
41 https://doi.org/10.1056/nejmoa1504030
42 https://doi.org/10.1056/nejmoa1611299
43 https://doi.org/10.1080/02841860500482225
44 https://doi.org/10.1080/15548627.2015.1082022
45 https://doi.org/10.1080/2162402x.2015.1137418
46 https://doi.org/10.1080/2162402x.2016.1235107
47 https://doi.org/10.1093/annonc/mdt027
48 https://doi.org/10.1093/annonc/mdt161
49 https://doi.org/10.1093/jnci/djq310
50 https://doi.org/10.1111/his.12537
51 https://doi.org/10.1126/scitranslmed.3003634
52 https://doi.org/10.1126/scitranslmed.3003689
53 https://doi.org/10.1126/scitranslmed.aaa3643
54 https://doi.org/10.1158/0008-5472.can-13-1794
55 https://doi.org/10.1158/0008-5472.can-15-2303
56 https://doi.org/10.1158/1078-0432.ccr-09-1624
57 https://doi.org/10.1158/1078-0432.ccr-13-2234
58 https://doi.org/10.1158/1078-0432.ccr-14-3128
59 https://doi.org/10.1158/1078-0432.ccr-14-3253
60 https://doi.org/10.1158/1078-0432.ccr-15-0612
61 https://doi.org/10.1158/1078-0432.ccr-15-2412
62 https://doi.org/10.1158/1078-0432.ccr-15-3104
63 https://doi.org/10.1158/1078-0432.ccr-16-0127
64 https://doi.org/10.1158/2326-6066.cir-13-0020
65 https://doi.org/10.1158/2326-6066.cir-14-0013
66 https://doi.org/10.1158/2326-6066.cir-15-0193
67 https://doi.org/10.1172/jci80071
68 https://doi.org/10.1172/jci81217
69 https://doi.org/10.1189/jlb.2mr0215-055r
70 https://doi.org/10.1200/jco.2009.26.7609
71 https://doi.org/10.1200/jco.2014.58.1967
72 https://doi.org/10.1200/jco.2016.34.15_suppl.9586
73 https://doi.org/10.1371/journal.pone.0084927
74 schema:datePublished 2017-12
75 schema:datePublishedReg 2017-12-01
76 schema:description Immune checkpoint blockers (ICB) have become pivotal therapies in the clinical armamentarium against metastatic melanoma (MMel). Given the frequency of immune related adverse events and increasing use of ICB, predictors of response to CTLA-4 and/or PD-1 blockade represent unmet clinical needs. Using a systems biology-based approach to an assessment of 779 paired blood and tumor markers in 37 stage III MMel patients, we analyzed association between blood immune parameters and the functional immune reactivity of tumor-infiltrating cells after ex vivo exposure to ICB. Based on this assay, we retrospectively observed, in eight cohorts enrolling 190 MMel patients treated with ipilimumab, that PD-L1 expression on peripheral T cells was prognostic on overall and progression-free survival. Moreover, detectable CD137 on circulating CD8<sup>+</sup> T cells was associated with the disease-free status of resected stage III MMel patients after adjuvant ipilimumab + nivolumab (but not nivolumab alone). These biomarkers should be validated in prospective trials in MMel.The clinical management of metastatic melanoma requires predictors of the response to checkpoint blockade. Here, the authors use immunological assays to identify potential prognostic/predictive biomarkers in circulating blood cells and in tumor-infiltrating lymphocytes from patients with resected stage III melanoma.
77 schema:genre research_article
78 schema:inLanguage en
79 schema:isAccessibleForFree true
80 schema:isPartOf N1c18e8da455d4033b26d6bb556841c0c
81 N8a0f1c1bf61e42bbbb1d93b9a321b91a
82 sg:journal.1043282
83 schema:name Predictors of responses to immune checkpoint blockade in advanced melanoma
84 schema:pagination 592
85 schema:productId N23b2206543754b2abffa233060705e75
86 N37f4aff4005e44a2b8a954e99b52c1bd
87 N6d79919e56b04fd7b346234582c47c1a
88 N9c0bda575ea742c89492487eb329d840
89 Na79d510dfc784eea9d33b80fd9ec6e15
90 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091688617
91 https://doi.org/10.1038/s41467-017-00608-2
92 schema:sdDatePublished 2019-04-11T01:21
93 schema:sdLicense https://scigraph.springernature.com/explorer/license/
94 schema:sdPublisher N90f536cbcdcc45f6864c80423f14db4d
95 schema:url https://www.nature.com/articles/s41467-017-00608-2
96 sgo:license sg:explorer/license/
97 sgo:sdDataset articles
98 rdf:type schema:ScholarlyArticle
99 N01c78d21c4d94ef388cc0e98b4963482 rdf:first N3e99297cd42f464c89223adaba947631
100 rdf:rest N64451d17cddf4cdd9bf172ef89450964
101 N01dcb48d88a3453eb192ab139947d424 rdf:first sg:person.01020424360.96
102 rdf:rest Ne40fce6067084893a611da3bb819929c
103 N138a5a2a611b4a1c94dc3f26ee441035 rdf:first Nfa8a2630f79543359aabc7dcdff4b372
104 rdf:rest Naf50389a821d41a59fd72aa57d77a945
105 N1b76b8fc884645328c5a8083d2e68ffd rdf:first sg:person.01061427172.10
106 rdf:rest N6bfcb2dc62834b458512ee6237566803
107 N1c18e8da455d4033b26d6bb556841c0c schema:issueNumber 1
108 rdf:type schema:PublicationIssue
109 N201f6d01a0cc426da3a795c7b7a70233 schema:affiliation https://www.grid.ac/institutes/grid.411477.0
110 schema:familyName Di Giacomo
111 schema:givenName A. M.
112 rdf:type schema:Person
113 N23b2206543754b2abffa233060705e75 schema:name pubmed_id
114 schema:value 28928380
115 rdf:type schema:PropertyValue
116 N24682b7ad37d4157a0bfe3752f22acb8 rdf:first sg:person.01012276550.27
117 rdf:rest Nf0e291a679434b9b9288491484ac220a
118 N2706fdad2c584dd69cd007fe5cefc643 rdf:first Nb0038db37cf34d3c9e60c191ef226b3a
119 rdf:rest N8bbacd1ef2ad495da4870cfbf3236ec8
120 N2a73ad72da1b4320b1b460f8d036e37d rdf:first sg:person.0676714763.05
121 rdf:rest Naff37782d4374b53ad0e02c6ad620751
122 N355cf917eb994fc68d1f2d8c963577b2 rdf:first sg:person.01153060003.44
123 rdf:rest N5f403cf63ee6482998e705152c6734b2
124 N3568c5b691734c419d40f69b2c8c7298 schema:affiliation N84b099622748440a973b76da5913699f
125 schema:familyName Aubin
126 schema:givenName F.
127 rdf:type schema:Person
128 N37f4aff4005e44a2b8a954e99b52c1bd schema:name dimensions_id
129 schema:value pub.1091688617
130 rdf:type schema:PropertyValue
131 N3e99297cd42f464c89223adaba947631 schema:affiliation Nc56f42edba0e4f9a821f1a7441256ddc
132 schema:familyName Levesque
133 schema:givenName M.
134 rdf:type schema:Person
135 N3f6d11b7a3e2443aa3a44366e2f5fa27 rdf:first sg:person.0746230417.54
136 rdf:rest N01dcb48d88a3453eb192ab139947d424
137 N410e697039b94276b3f8adcee87798d7 schema:affiliation https://www.grid.ac/institutes/grid.415337.7
138 schema:familyName Koguchi
139 schema:givenName Y.
140 rdf:type schema:Person
141 N4362991cb9a149bead3e4feffd5064d7 rdf:first sg:person.01006244063.07
142 rdf:rest N138a5a2a611b4a1c94dc3f26ee441035
143 N443f44d456eb47a78bf3e61273cb9c1d rdf:first sg:person.011243423402.43
144 rdf:rest Naff7c197bd1b4121b647ccc340285c17
145 N4bdde143f02b45a184131df5153dc1ea rdf:first sg:person.01160336661.40
146 rdf:rest N7f72c49f78254918b44e1c0e4f20a326
147 N4d3204798caf41ac9c2ed000060cb5c2 rdf:first sg:person.01010600434.98
148 rdf:rest N6c0a357c3c5549f5a6af3133da8b3408
149 N50061e1ee513410da8bb45376548476f rdf:first sg:person.01341501713.19
150 rdf:rest N95b2cee08e5c43419295804f7d7b4f8c
151 N5a12fa8033c241459ee24e711465a33f rdf:first sg:person.0665460265.17
152 rdf:rest N610a64642ef645559cc12e4513aab7e4
153 N5f403cf63ee6482998e705152c6734b2 rdf:first sg:person.01060723265.49
154 rdf:rest Nc73abe9c3bdd40598fd6401fc7b23b04
155 N5fadf6a1b0bd4657a5a9dfaba25e2c52 rdf:first Necc074c0b0174b9d861d6cd63ae57e91
156 rdf:rest N68a83b6617944d169a157a20d96f4866
157 N610a64642ef645559cc12e4513aab7e4 rdf:first N201f6d01a0cc426da3a795c7b7a70233
158 rdf:rest N1b76b8fc884645328c5a8083d2e68ffd
159 N63e68a12aa21432d93cb1a629ee7441e rdf:first sg:person.0622221332.57
160 rdf:rest N2706fdad2c584dd69cd007fe5cefc643
161 N64451d17cddf4cdd9bf172ef89450964 rdf:first N410e697039b94276b3f8adcee87798d7
162 rdf:rest N443f44d456eb47a78bf3e61273cb9c1d
163 N68a83b6617944d169a157a20d96f4866 rdf:first Na973dc9e757a494a9b30ec732742cc66
164 rdf:rest N24682b7ad37d4157a0bfe3752f22acb8
165 N6bfcb2dc62834b458512ee6237566803 rdf:first Nfb4da767cea1477b8350aaf88f2dc0a6
166 rdf:rest N7617bc4928b64fbb94876138288b93e1
167 N6c0a357c3c5549f5a6af3133da8b3408 rdf:first Nfb138c55bc544d21aefd74b923342dec
168 rdf:rest N97ad4b9f2dc0467ebae69477ea6f7a2d
169 N6d79919e56b04fd7b346234582c47c1a schema:name doi
170 schema:value 10.1038/s41467-017-00608-2
171 rdf:type schema:PropertyValue
172 N74de7c1c17204d57ac1a1da083415135 rdf:first Nd1a16ae41803404fb5986cd40569e1b2
173 rdf:rest N3f6d11b7a3e2443aa3a44366e2f5fa27
174 N7617bc4928b64fbb94876138288b93e1 rdf:first sg:person.0777142412.98
175 rdf:rest Nad12bb4216da4e40b9032ca4526f0eb5
176 N77cf586709cd44478d19262ba2274bf8 rdf:first sg:person.01170777250.79
177 rdf:rest Nbabb8c2a1b1648a5a8604da933bef112
178 N790ba310690a48ed8e88569f56643470 rdf:first Nfc651882a4624bfca57c62769f248422
179 rdf:rest N01c78d21c4d94ef388cc0e98b4963482
180 N7ab27704ceca455bb866c5baa9560b5a schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
181 schema:familyName Roberti
182 schema:givenName M. P.
183 rdf:type schema:Person
184 N7f72c49f78254918b44e1c0e4f20a326 rdf:first Nf6da7cc8d5c94b06bf63437c0313ee4f
185 rdf:rest N5fadf6a1b0bd4657a5a9dfaba25e2c52
186 N82cd79fcea334b9287dee0f79d525587 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
187 schema:familyName Eggermont
188 schema:givenName A. M.
189 rdf:type schema:Person
190 N84b099622748440a973b76da5913699f schema:name Université de Franche Comté, EA3181, SFR4234, Service de Dermatologie, Centre Hospitalier Universitaire (CHU), 25000, Besançon, France
191 rdf:type schema:Organization
192 N8a0f1c1bf61e42bbbb1d93b9a321b91a schema:volumeNumber 8
193 rdf:type schema:PublicationVolume
194 N8bbacd1ef2ad495da4870cfbf3236ec8 rdf:first sg:person.0754740703.61
195 rdf:rest N4bdde143f02b45a184131df5153dc1ea
196 N90f536cbcdcc45f6864c80423f14db4d schema:name Springer Nature - SN SciGraph project
197 rdf:type schema:Organization
198 N95b2cee08e5c43419295804f7d7b4f8c rdf:first sg:person.0657152274.85
199 rdf:rest Nb29f4935bd3d44efabc610f0df49af30
200 N96cfd2786d4b4856b260547847439e30 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
201 schema:familyName Duong
202 schema:givenName C. P. M.
203 rdf:type schema:Person
204 N97ad4b9f2dc0467ebae69477ea6f7a2d rdf:first N82cd79fcea334b9287dee0f79d525587
205 rdf:rest Nbf0bccc6ad8c428fa2916ae9171f4742
206 N9c0bda575ea742c89492487eb329d840 schema:name nlm_unique_id
207 schema:value 101528555
208 rdf:type schema:PropertyValue
209 Na10e7f472e6f46f1aa0622ba3026d393 rdf:first Ncb171ebc5c74457ea7ffe5733536ef47
210 rdf:rest N63e68a12aa21432d93cb1a629ee7441e
211 Na79d510dfc784eea9d33b80fd9ec6e15 schema:name readcube_id
212 schema:value 233385b8aa09e68f674b428cbf66cc330e999386b29062ee74252abfe2b46c1d
213 rdf:type schema:PropertyValue
214 Na973dc9e757a494a9b30ec732742cc66 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
215 schema:familyName Flament
216 schema:givenName C.
217 rdf:type schema:Person
218 Naca2a2b9d2514e4cb17c1a3e233e651c schema:name Department of Dermatology, University Hospital Zürich and University of Zürich, 8091, Zürich, Switzerland
219 rdf:type schema:Organization
220 Nad12bb4216da4e40b9032ca4526f0eb5 rdf:first sg:person.01146563400.12
221 rdf:rest Nb71fb94ca1cf4738adaeadaab2def602
222 Naf50389a821d41a59fd72aa57d77a945 rdf:first sg:person.0635206541.65
223 rdf:rest N74de7c1c17204d57ac1a1da083415135
224 Naff37782d4374b53ad0e02c6ad620751 rdf:first sg:person.0700425476.95
225 rdf:rest Nb3c13c1502324f619a9aaeafb6035c21
226 Naff7c197bd1b4121b647ccc340285c17 rdf:first sg:person.01062103030.57
227 rdf:rest N4362991cb9a149bead3e4feffd5064d7
228 Nb0038db37cf34d3c9e60c191ef226b3a schema:affiliation https://www.grid.ac/institutes/grid.411900.d
229 schema:familyName Hansen
230 schema:givenName M.
231 rdf:type schema:Person
232 Nb29f4935bd3d44efabc610f0df49af30 rdf:first sg:person.0770276230.45
233 rdf:rest Nc9dd43d9bf344bb5a593279888ef7ebb
234 Nb3c13c1502324f619a9aaeafb6035c21 rdf:first sg:person.01314673254.79
235 rdf:rest Nf1e330bc74c040019858d39cc6ba0609
236 Nb4598630309d4ed2be4a95b948379550 rdf:first sg:person.01322650310.99
237 rdf:rest Nfec64af5832d44dcb0c54a3c1b843ed0
238 Nb71fb94ca1cf4738adaeadaab2def602 rdf:first sg:person.0717176144.55
239 rdf:rest N790ba310690a48ed8e88569f56643470
240 Nbabb8c2a1b1648a5a8604da933bef112 rdf:first N7ab27704ceca455bb866c5baa9560b5a
241 rdf:rest N50061e1ee513410da8bb45376548476f
242 Nbf0bccc6ad8c428fa2916ae9171f4742 rdf:first sg:person.01214767546.51
243 rdf:rest rdf:nil
244 Nc56f42edba0e4f9a821f1a7441256ddc schema:name Department of Dermatology, University Hospital Zürich and University of Zürich, 8091, Zürich, Switzerland
245 rdf:type schema:Organization
246 Nc73abe9c3bdd40598fd6401fc7b23b04 rdf:first sg:person.01054702726.78
247 rdf:rest Nb4598630309d4ed2be4a95b948379550
248 Nc9dd43d9bf344bb5a593279888ef7ebb rdf:first sg:person.01005217353.34
249 rdf:rest Na10e7f472e6f46f1aa0622ba3026d393
250 Ncb171ebc5c74457ea7ffe5733536ef47 schema:affiliation https://www.grid.ac/institutes/grid.240324.3
251 schema:familyName Woods
252 schema:givenName D. M.
253 rdf:type schema:Person
254 Nce03be63b2ad488c94b5d59aa558051a schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
255 schema:familyName Cavalcanti
256 schema:givenName A.
257 rdf:type schema:Person
258 Nd1a16ae41803404fb5986cd40569e1b2 schema:affiliation https://www.grid.ac/institutes/grid.414093.b
259 schema:familyName Kroemer
260 schema:givenName G.
261 rdf:type schema:Person
262 Ne40fce6067084893a611da3bb819929c rdf:first Nce03be63b2ad488c94b5d59aa558051a
263 rdf:rest N4d3204798caf41ac9c2ed000060cb5c2
264 Ne786e8f5bfa04dfb88e62b16c21dd295 rdf:first sg:person.015361211617.31
265 rdf:rest N2a73ad72da1b4320b1b460f8d036e37d
266 Necc074c0b0174b9d861d6cd63ae57e91 schema:affiliation https://www.grid.ac/institutes/grid.266102.1
267 schema:familyName Kwek
268 schema:givenName S. S.
269 rdf:type schema:Person
270 Nf0e291a679434b9b9288491484ac220a rdf:first N96cfd2786d4b4856b260547847439e30
271 rdf:rest Nfba52a9ac285479cbd556ced1bc08900
272 Nf1e330bc74c040019858d39cc6ba0609 rdf:first N3568c5b691734c419d40f69b2c8c7298
273 rdf:rest N355cf917eb994fc68d1f2d8c963577b2
274 Nf6da7cc8d5c94b06bf63437c0313ee4f schema:affiliation https://www.grid.ac/institutes/grid.266102.1
275 schema:familyName Burra
276 schema:givenName A.
277 rdf:type schema:Person
278 Nfa8a2630f79543359aabc7dcdff4b372 schema:affiliation https://www.grid.ac/institutes/grid.154185.c
279 schema:familyName Schmidt
280 schema:givenName H.
281 rdf:type schema:Person
282 Nfb138c55bc544d21aefd74b923342dec schema:affiliation https://www.grid.ac/institutes/grid.240324.3
283 schema:familyName Weber
284 schema:givenName J. S.
285 rdf:type schema:Person
286 Nfb4da767cea1477b8350aaf88f2dc0a6 schema:affiliation https://www.grid.ac/institutes/grid.5718.b
287 schema:familyName Schadendorf
288 schema:givenName D.
289 rdf:type schema:Person
290 Nfba52a9ac285479cbd556ced1bc08900 rdf:first sg:person.016303325577.21
291 rdf:rest Ne786e8f5bfa04dfb88e62b16c21dd295
292 Nfc651882a4624bfca57c62769f248422 schema:affiliation Naca2a2b9d2514e4cb17c1a3e233e651c
293 schema:familyName Dummer
294 schema:givenName R.
295 rdf:type schema:Person
296 Nfec64af5832d44dcb0c54a3c1b843ed0 rdf:first sg:person.01323064306.36
297 rdf:rest N5a12fa8033c241459ee24e711465a33f
298 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
299 schema:name Medical and Health Sciences
300 rdf:type schema:DefinedTerm
301 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
302 schema:name Immunology
303 rdf:type schema:DefinedTerm
304 sg:grant.3932694 http://pending.schema.org/fundedItem sg:pub.10.1038/s41467-017-00608-2
305 rdf:type schema:MonetaryGrant
306 sg:journal.1043282 schema:issn 2041-1723
307 schema:name Nature Communications
308 rdf:type schema:Periodical
309 sg:person.01005217353.34 schema:affiliation https://www.grid.ac/institutes/grid.412370.3
310 schema:familyName Jegou
311 schema:givenName S.
312 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01005217353.34
313 rdf:type schema:Person
314 sg:person.01006244063.07 schema:affiliation https://www.grid.ac/institutes/grid.9619.7
315 schema:familyName Baniyash
316 schema:givenName M.
317 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01006244063.07
318 rdf:type schema:Person
319 sg:person.01010600434.98 schema:affiliation https://www.grid.ac/institutes/grid.1003.2
320 schema:familyName Smyth
321 schema:givenName M. J.
322 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01010600434.98
323 rdf:type schema:Person
324 sg:person.01012276550.27 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
325 schema:familyName Messaoudene
326 schema:givenName M.
327 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012276550.27
328 rdf:type schema:Person
329 sg:person.01020424360.96 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
330 schema:familyName Michiels
331 schema:givenName S.
332 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020424360.96
333 rdf:type schema:Person
334 sg:person.01054702726.78 schema:affiliation https://www.grid.ac/institutes/grid.411430.3
335 schema:familyName Beatrix
336 schema:givenName O.
337 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054702726.78
338 rdf:type schema:Person
339 sg:person.01060723265.49 schema:affiliation https://www.grid.ac/institutes/grid.462282.8
340 schema:familyName Dalle
341 schema:givenName S.
342 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060723265.49
343 rdf:type schema:Person
344 sg:person.01061427172.10 schema:affiliation https://www.grid.ac/institutes/grid.411477.0
345 schema:familyName Maio
346 schema:givenName M.
347 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01061427172.10
348 rdf:type schema:Person
349 sg:person.01062103030.57 schema:affiliation https://www.grid.ac/institutes/grid.17788.31
350 schema:familyName Lotem
351 schema:givenName M.
352 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062103030.57
353 rdf:type schema:Person
354 sg:person.011243423402.43 schema:affiliation https://www.grid.ac/institutes/grid.266102.1
355 schema:familyName Fong
356 schema:givenName L.
357 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011243423402.43
358 rdf:type schema:Person
359 sg:person.01146563400.12 schema:affiliation https://www.grid.ac/institutes/grid.277151.7
360 schema:familyName Dréno
361 schema:givenName B.
362 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01146563400.12
363 rdf:type schema:Person
364 sg:person.01153060003.44 schema:affiliation https://www.grid.ac/institutes/grid.7459.f
365 schema:familyName Borg
366 schema:givenName C.
367 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01153060003.44
368 rdf:type schema:Person
369 sg:person.01160336661.40 schema:affiliation https://www.grid.ac/institutes/grid.9619.7
370 schema:familyName Sade-Feldman
371 schema:givenName M.
372 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01160336661.40
373 rdf:type schema:Person
374 sg:person.01170777250.79 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
375 schema:familyName Jacquelot
376 schema:givenName N.
377 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170777250.79
378 rdf:type schema:Person
379 sg:person.01214767546.51 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
380 schema:familyName Zitvogel
381 schema:givenName L.
382 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01214767546.51
383 rdf:type schema:Person
384 sg:person.01314673254.79 schema:affiliation https://www.grid.ac/institutes/grid.411544.1
385 schema:familyName Weide
386 schema:givenName B.
387 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01314673254.79
388 rdf:type schema:Person
389 sg:person.01322650310.99 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
390 schema:familyName Ayyoub
391 schema:givenName M.
392 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01322650310.99
393 rdf:type schema:Person
394 sg:person.01323064306.36 schema:affiliation https://www.grid.ac/institutes/grid.413852.9
395 schema:familyName Balme
396 schema:givenName B.
397 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01323064306.36
398 rdf:type schema:Person
399 sg:person.01341501713.19 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
400 schema:familyName Enot
401 schema:givenName D. P.
402 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341501713.19
403 rdf:type schema:Person
404 sg:person.015361211617.31 schema:affiliation https://www.grid.ac/institutes/grid.265219.b
405 schema:familyName Kwon
406 schema:givenName B. S.
407 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015361211617.31
408 rdf:type schema:Person
409 sg:person.016303325577.21 schema:affiliation https://www.grid.ac/institutes/grid.47100.32
410 schema:familyName Chen
411 schema:givenName L.
412 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016303325577.21
413 rdf:type schema:Person
414 sg:person.0622221332.57 schema:affiliation https://www.grid.ac/institutes/grid.240324.3
415 schema:familyName Sodré
416 schema:givenName A. L.
417 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622221332.57
418 rdf:type schema:Person
419 sg:person.0635206541.65 schema:affiliation https://www.grid.ac/institutes/grid.411900.d
420 schema:familyName Svane
421 schema:givenName I. M.
422 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0635206541.65
423 rdf:type schema:Person
424 sg:person.0657152274.85 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
425 schema:familyName Rusakiewicz
426 schema:givenName S.
427 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657152274.85
428 rdf:type schema:Person
429 sg:person.0665460265.17 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
430 schema:familyName Tomasic
431 schema:givenName G.
432 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0665460265.17
433 rdf:type schema:Person
434 sg:person.0676714763.05 schema:affiliation https://www.grid.ac/institutes/grid.38142.3c
435 schema:familyName Anderson
436 schema:givenName A. C.
437 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0676714763.05
438 rdf:type schema:Person
439 sg:person.0700425476.95 schema:affiliation https://www.grid.ac/institutes/grid.38142.3c
440 schema:familyName Kuchroo
441 schema:givenName V. K.
442 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700425476.95
443 rdf:type schema:Person
444 sg:person.0717176144.55 schema:affiliation https://www.grid.ac/institutes/grid.277151.7
445 schema:familyName Khammari
446 schema:givenName A.
447 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717176144.55
448 rdf:type schema:Person
449 sg:person.0746230417.54 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
450 schema:familyName Marabelle
451 schema:givenName A.
452 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0746230417.54
453 rdf:type schema:Person
454 sg:person.0754740703.61 schema:affiliation https://www.grid.ac/institutes/grid.9619.7
455 schema:familyName Meirow
456 schema:givenName Y.
457 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0754740703.61
458 rdf:type schema:Person
459 sg:person.0770276230.45 schema:affiliation https://www.grid.ac/institutes/grid.14925.3b
460 schema:familyName Ternès
461 schema:givenName N.
462 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0770276230.45
463 rdf:type schema:Person
464 sg:person.0777142412.98 schema:affiliation https://www.grid.ac/institutes/grid.411730.0
465 schema:familyName Melero
466 schema:givenName I.
467 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0777142412.98
468 rdf:type schema:Person
469 sg:pub.10.1007/s00262-011-1172-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009295521
470 https://doi.org/10.1007/s00262-011-1172-6
471 rdf:type schema:CreativeWork
472 sg:pub.10.1007/s00268-002-6378-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018719615
473 https://doi.org/10.1007/s00268-002-6378-5
474 rdf:type schema:CreativeWork
475 sg:pub.10.1007/s12253-008-9109-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1004056254
476 https://doi.org/10.1007/s12253-008-9109-x
477 rdf:type schema:CreativeWork
478 sg:pub.10.1007/s12253-012-9512-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037319234
479 https://doi.org/10.1007/s12253-012-9512-1
480 rdf:type schema:CreativeWork
481 sg:pub.10.1038/cr.2015.3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008573304
482 https://doi.org/10.1038/cr.2015.3
483 rdf:type schema:CreativeWork
484 sg:pub.10.1038/nature12213 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021761707
485 https://doi.org/10.1038/nature12213
486 rdf:type schema:CreativeWork
487 sg:pub.10.1038/nature13954 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020455470
488 https://doi.org/10.1038/nature13954
489 rdf:type schema:CreativeWork
490 sg:pub.10.1038/ng.3677 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052106779
491 https://doi.org/10.1038/ng.3677
492 rdf:type schema:CreativeWork
493 sg:pub.10.1038/nm.3541 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039587457
494 https://doi.org/10.1038/nm.3541
495 rdf:type schema:CreativeWork
496 sg:pub.10.1038/nrclinonc.2015.106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026995724
497 https://doi.org/10.1038/nrclinonc.2015.106
498 rdf:type schema:CreativeWork
499 sg:pub.10.1186/1479-5876-3-10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033807595
500 https://doi.org/10.1186/1479-5876-3-10
501 rdf:type schema:CreativeWork
502 sg:pub.10.1186/1479-5876-9-204 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002969174
503 https://doi.org/10.1186/1479-5876-9-204
504 rdf:type schema:CreativeWork
505 https://app.dimensions.ai/details/publication/pub.1074559855 schema:CreativeWork
506 https://app.dimensions.ai/details/publication/pub.1074813226 schema:CreativeWork
507 https://app.dimensions.ai/details/publication/pub.1078245726 schema:CreativeWork
508 https://doi.org/10.1002/cncr.24951 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018207285
509 rdf:type schema:CreativeWork
510 https://doi.org/10.1002/ijc.21264 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012911980
511 rdf:type schema:CreativeWork
512 https://doi.org/10.1016/j.ccell.2015.03.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053023000
513 rdf:type schema:CreativeWork
514 https://doi.org/10.1016/j.cell.2015.03.045 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033378425
515 rdf:type schema:CreativeWork
516 https://doi.org/10.1016/j.cell.2015.08.052 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024088208
517 rdf:type schema:CreativeWork
518 https://doi.org/10.1016/j.cell.2016.11.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009220256
519 rdf:type schema:CreativeWork
520 https://doi.org/10.1016/j.celrep.2015.08.077 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034973964
521 rdf:type schema:CreativeWork
522 https://doi.org/10.1016/j.jid.2015.12.042 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008425988
523 rdf:type schema:CreativeWork
524 https://doi.org/10.1016/j.molonc.2015.10.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003821098
525 rdf:type schema:CreativeWork
526 https://doi.org/10.1016/s0140-6736(13)60802-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043729077
527 rdf:type schema:CreativeWork
528 https://doi.org/10.1016/s1470-2045(15)70122-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003860539
529 rdf:type schema:CreativeWork
530 https://doi.org/10.1016/s1470-2045(16)30366-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001468571
531 rdf:type schema:CreativeWork
532 https://doi.org/10.1016/s1470-2045(16)30624-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034482273
533 rdf:type schema:CreativeWork
534 https://doi.org/10.1016/s2213-2600(13)70159-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024358603
535 rdf:type schema:CreativeWork
536 https://doi.org/10.1046/j.1365-2133.2002.04745.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014774895
537 rdf:type schema:CreativeWork
538 https://doi.org/10.1053/j.seminoncol.2010.09.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052798261
539 rdf:type schema:CreativeWork
540 https://doi.org/10.1053/j.seminoncol.2015.02.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021039257
541 rdf:type schema:CreativeWork
542 https://doi.org/10.1056/nejmoa1001294 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017807249
543 rdf:type schema:CreativeWork
544 https://doi.org/10.1056/nejmoa1200694 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047413837
545 rdf:type schema:CreativeWork
546 https://doi.org/10.1056/nejmoa1406498 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020435459
547 rdf:type schema:CreativeWork
548 https://doi.org/10.1056/nejmoa1414428 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007696832
549 rdf:type schema:CreativeWork
550 https://doi.org/10.1056/nejmoa1501824 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031881319
551 rdf:type schema:CreativeWork
552 https://doi.org/10.1056/nejmoa1504030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024843336
553 rdf:type schema:CreativeWork
554 https://doi.org/10.1056/nejmoa1611299 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020609326
555 rdf:type schema:CreativeWork
556 https://doi.org/10.1080/02841860500482225 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040084577
557 rdf:type schema:CreativeWork
558 https://doi.org/10.1080/15548627.2015.1082022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058406596
559 rdf:type schema:CreativeWork
560 https://doi.org/10.1080/2162402x.2015.1137418 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058420687
561 rdf:type schema:CreativeWork
562 https://doi.org/10.1080/2162402x.2016.1235107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058420771
563 rdf:type schema:CreativeWork
564 https://doi.org/10.1093/annonc/mdt027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008750772
565 rdf:type schema:CreativeWork
566 https://doi.org/10.1093/annonc/mdt161 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024839180
567 rdf:type schema:CreativeWork
568 https://doi.org/10.1093/jnci/djq310 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037022855
569 rdf:type schema:CreativeWork
570 https://doi.org/10.1111/his.12537 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037223091
571 rdf:type schema:CreativeWork
572 https://doi.org/10.1126/scitranslmed.3003634 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020921605
573 rdf:type schema:CreativeWork
574 https://doi.org/10.1126/scitranslmed.3003689 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018365419
575 rdf:type schema:CreativeWork
576 https://doi.org/10.1126/scitranslmed.aaa3643 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046673496
577 rdf:type schema:CreativeWork
578 https://doi.org/10.1158/0008-5472.can-13-1794 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049860235
579 rdf:type schema:CreativeWork
580 https://doi.org/10.1158/0008-5472.can-15-2303 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008301360
581 rdf:type schema:CreativeWork
582 https://doi.org/10.1158/1078-0432.ccr-09-1624 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028571226
583 rdf:type schema:CreativeWork
584 https://doi.org/10.1158/1078-0432.ccr-13-2234 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040432582
585 rdf:type schema:CreativeWork
586 https://doi.org/10.1158/1078-0432.ccr-14-3128 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025700448
587 rdf:type schema:CreativeWork
588 https://doi.org/10.1158/1078-0432.ccr-14-3253 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025801974
589 rdf:type schema:CreativeWork
590 https://doi.org/10.1158/1078-0432.ccr-15-0612 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045903927
591 rdf:type schema:CreativeWork
592 https://doi.org/10.1158/1078-0432.ccr-15-2412 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008399758
593 rdf:type schema:CreativeWork
594 https://doi.org/10.1158/1078-0432.ccr-15-3104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063225302
595 rdf:type schema:CreativeWork
596 https://doi.org/10.1158/1078-0432.ccr-16-0127 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063225334
597 rdf:type schema:CreativeWork
598 https://doi.org/10.1158/2326-6066.cir-13-0020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019042882
599 rdf:type schema:CreativeWork
600 https://doi.org/10.1158/2326-6066.cir-14-0013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021999618
601 rdf:type schema:CreativeWork
602 https://doi.org/10.1158/2326-6066.cir-15-0193 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029683691
603 rdf:type schema:CreativeWork
604 https://doi.org/10.1172/jci80071 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029324712
605 rdf:type schema:CreativeWork
606 https://doi.org/10.1172/jci81217 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018400866
607 rdf:type schema:CreativeWork
608 https://doi.org/10.1189/jlb.2mr0215-055r schema:sameAs https://app.dimensions.ai/details/publication/pub.1022591957
609 rdf:type schema:CreativeWork
610 https://doi.org/10.1200/jco.2009.26.7609 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020897568
611 rdf:type schema:CreativeWork
612 https://doi.org/10.1200/jco.2014.58.1967 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006980479
613 rdf:type schema:CreativeWork
614 https://doi.org/10.1200/jco.2016.34.15_suppl.9586 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106842906
615 rdf:type schema:CreativeWork
616 https://doi.org/10.1371/journal.pone.0084927 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028199095
617 rdf:type schema:CreativeWork
618 https://www.grid.ac/institutes/grid.1003.2 schema:alternateName University of Queensland
619 schema:name Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, 4006, Herston, QLD, Australia
620 School of Medicine, University of Queensland, 4006, Herston, QLD, Australia
621 rdf:type schema:Organization
622 https://www.grid.ac/institutes/grid.14925.3b schema:alternateName Institut Gustave Roussy
623 schema:name CIC1428, Gustave Roussy Cancer Campus, 94800, Villejuif, France
624 Department of Dermatology, Gustave Roussy Cancer Center, 94800, Villejuif, France
625 Department of Pathology, Gustave Roussy Cancer Campus, 94800, Villejuif, France
626 Department of Surgery, Gustave Roussy Cancer Center, 94800, Villejuif, France
627 Gustave Roussy Cancer Campus, 94800, Villejuif, France
628 Gustave Roussy, Université Paris-Saclay, Service de Biostatistique et d’Epidémiologie, F-94805, Villejuif, France
629 INSERM U1015, Gustave Roussy Cancer Campus, 94800, Villejuif, France
630 Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, 94800, Villejuif, France
631 University Paris-Saclay, 94 276, Kremlin Bicêtre, France
632 rdf:type schema:Organization
633 https://www.grid.ac/institutes/grid.154185.c schema:alternateName Aarhus University Hospital
634 schema:name Department of Oncology, Aarhus University Hospital, DK-8200, Aarhus, Denmark
635 rdf:type schema:Organization
636 https://www.grid.ac/institutes/grid.17788.31 schema:alternateName Hadassah Medical Center
637 schema:name Sharett Institute of Oncology, Hadassah Medical Organization, 91120, Jerusalem, Israel
638 rdf:type schema:Organization
639 https://www.grid.ac/institutes/grid.240324.3 schema:alternateName New York University Langone Medical Center
640 schema:name Laura & Isaac Perlmutter Cancer Center, New York University Medical Center, 10016, New York, NY, USA
641 rdf:type schema:Organization
642 https://www.grid.ac/institutes/grid.265219.b schema:alternateName Tulane University
643 schema:name Eutilex, Suite# 1401 Daeryung Technotown 17 Gasan Digital 1-ro 25, 08594, Geumcheon-gu, Seoul, Korea
644 Section of Clinical Immunology, Allergy, and Rheumatology, Department of Medicine, Tulane University Health Sciences Center, 70112, New Orleans, LA, USA
645 rdf:type schema:Organization
646 https://www.grid.ac/institutes/grid.266102.1 schema:alternateName University of California, San Francisco
647 schema:name Division of Hematology/Oncology, Department of Medicine, University of California, 94143, San Francisco, CA, USA
648 rdf:type schema:Organization
649 https://www.grid.ac/institutes/grid.277151.7 schema:alternateName Centre Hospitalier Universitaire de Nantes
650 schema:name Department of Onco-dermatology, CIC Biotherapy, INSERM U1232, CHU Nantes, 44000, Nantes, France
651 rdf:type schema:Organization
652 https://www.grid.ac/institutes/grid.38142.3c schema:alternateName Harvard University
653 schema:name Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Brigham and Women’s Hospital and Harvard Medical School, 02115, Boston, MA, USA
654 rdf:type schema:Organization
655 https://www.grid.ac/institutes/grid.411430.3 schema:alternateName Centre Hospitalier Lyon Sud
656 schema:name Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon and University Claude Bernard Lyon 1, 69000, Lyon, France
657 rdf:type schema:Organization
658 https://www.grid.ac/institutes/grid.411477.0 schema:alternateName Azienda Ospedaliera Universitaria Senese
659 schema:name Medical Oncology and Immunotherapy Division, University Hospital of Siena, Viale Bracci, 14, 53100, Siena, Italy
660 Medical Oncology and Immunotherapy, Department of Oncology, University Hospital of Siena, Instituto Toscano Tumori, 53100, Siena, Italy
661 rdf:type schema:Organization
662 https://www.grid.ac/institutes/grid.411544.1 schema:alternateName Universitätsklinikum Tübingen
663 schema:name Department of Dermatology, University Medical Center Tübingen, 72076, Tübingen, Germany
664 rdf:type schema:Organization
665 https://www.grid.ac/institutes/grid.411730.0 schema:alternateName Clinica Universidad de Navarra
666 schema:name Centro de Investigación cBiomedica en Red de Oncologia, 31008, Pamplona, Spain
667 Division of Gene Therapy and Hepatology, Centre for Applied Medical Research, 31008, Pamplona, Spain
668 Oncology Department, University Clinic of Navarra, 31008, Pamplona, Spain
669 rdf:type schema:Organization
670 https://www.grid.ac/institutes/grid.411900.d schema:alternateName Herlev Hospital
671 schema:name Center for Cancer Immune Therapy, Department of Hematology and Oncology, Copenhagen University Hospital, DK-2730, Herlev, Denmark
672 rdf:type schema:Organization
673 https://www.grid.ac/institutes/grid.412370.3 schema:alternateName Hôpital Saint-Antoine
674 schema:name Saint Antoine Hospital, INSERM ERL 1157-CNRS UMR 7203, 75005, Paris, France
675 rdf:type schema:Organization
676 https://www.grid.ac/institutes/grid.413852.9 schema:alternateName Hospices Civils de Lyon
677 schema:name Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon and University Claude Bernard Lyon 1, 69000, Lyon, France
678 Department of Pathology, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, 69000, Lyon, France
679 rdf:type schema:Organization
680 https://www.grid.ac/institutes/grid.414093.b schema:alternateName Hôpital Européen Georges-Pompidou
681 schema:name Equipe 11 labellisée par la Ligue contre le Cancer, Centre de Recherche des Cordeliers, 75006, Paris, France
682 Gustave Roussy Cancer Campus, 94800, Villejuif, France
683 INSERM U1138, Centre de Recherche des Cordeliers, 75006, Paris, France
684 Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, 94800, Villejuif, France
685 Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, 75015, Paris, France
686 Université Paris Descartes, Sorbonne Paris Cité, 75006, Paris, France
687 Université Pierre et Marie Curie, 75005, Paris, France
688 rdf:type schema:Organization
689 https://www.grid.ac/institutes/grid.415337.7 schema:alternateName Providence St. Vincent Medical Center
690 schema:name Earle A. Chiles Research Institute, Providence Cancer Center, 97213, Portland, OR, USA
691 rdf:type schema:Organization
692 https://www.grid.ac/institutes/grid.462282.8 schema:alternateName Cancer Center of Lyon
693 schema:name Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon and University Claude Bernard Lyon 1, 69000, Lyon, France
694 Centre de Recherche en Cancérologie de Lyon, 69000, Lyon, France
695 rdf:type schema:Organization
696 https://www.grid.ac/institutes/grid.47100.32 schema:alternateName Yale University
697 schema:name Department of Immunobiology, Yale School of Medicine, 10 Amistad Street, 06519, New Haven, CT, USA
698 rdf:type schema:Organization
699 https://www.grid.ac/institutes/grid.5718.b schema:alternateName University of Duisburg-Essen
700 schema:name Department of Dermatology, University Hospital, University Duisburg-Essen, Essen, Germany & German Cancer Consortium (DKTZ), D-69120, Heidelberg, Germany
701 rdf:type schema:Organization
702 https://www.grid.ac/institutes/grid.7459.f schema:alternateName University of Franche-Comté
703 schema:name Clinical Investigational Centre, CIC-1431, University Hospital of Besançon, 25030, Besançon, France
704 Department of Medical Oncology, University Hospital of Besancon, 3 Boulevard Alexander Fleming, F-25030, Besancon, France
705 INSERM U1098, University of Franche-Comté, 25020, Besançon, France
706 rdf:type schema:Organization
707 https://www.grid.ac/institutes/grid.9619.7 schema:alternateName Hebrew University of Jerusalem
708 schema:name The Lautenberg Center for General and Tumor Immunology, BioMedical Research institute Israel Canada of the Faculty of Medicine, The Hebrew University Hadassah Medical School, 91120, Jerusalem, Israel
709 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...