Ontology type: schema:ScholarlyArticle Open Access: True
2017-09-07
AUTHORSCayla E. Jewett, Timothy E. Vanderleest, Hui Miao, Yi Xie, Roopa Madhu, Dinah Loerke, J. Todd Blankenship
ABSTRACTThe coordination between membrane trafficking and actomyosin networks is essential to the regulation of cell and tissue shape. Here, we examine Rab protein distributions during Drosophila epithelial tissue remodeling and show that Rab35 is dynamically planar polarized. Rab35 compartments are enriched at contractile interfaces of intercalating cells and provide the first evidence of interfacial monopolarity. When Rab35 function is disrupted, apical area oscillations still occur and contractile steps are observed. However, contractions are followed by reversals and interfaces fail to shorten, demonstrating that Rab35 functions as a ratchet ensuring unidirectional movement. Although actomyosin forces have been thought to drive interface contraction, initiation of Rab35 compartments does not require Myosin II function. However, Rab35 compartments do not terminate and continue to grow into large elongated structures following actomyosin disruption. Finally, Rab35 represents a common contractile cell-shaping mechanism, as mesoderm invagination fails in Rab35 compromised embryos and Rab35 localizes to constricting surfaces. More... »
PAGES476
http://scigraph.springernature.com/pub.10.1038/s41467-017-00553-0
DOIhttp://dx.doi.org/10.1038/s41467-017-00553-0
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1091465435
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/28883443
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biological Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biochemistry and Cell Biology",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Actomyosin",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Animals",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Animals, Genetically Modified",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cell Compartmentation",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cell Membrane",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cell Polarity",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cell Shape",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Drosophila Proteins",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Drosophila melanogaster",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Endosomes",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Epithelial Cells",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Myosin Type II",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "rab GTP-Binding Proteins",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "rab5 GTP-Binding Proteins",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Department of Biological Sciences, University of Denver, 80208, Denver, CO, USA",
"id": "http://www.grid.ac/institutes/grid.266239.a",
"name": [
"Department of Biological Sciences, University of Denver, 80208, Denver, CO, USA"
],
"type": "Organization"
},
"familyName": "Jewett",
"givenName": "Cayla E.",
"id": "sg:person.01325560363.24",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01325560363.24"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Physics, University of Denver, 80208, Denver, CO, USA",
"id": "http://www.grid.ac/institutes/grid.266239.a",
"name": [
"Department of Physics, University of Denver, 80208, Denver, CO, USA"
],
"type": "Organization"
},
"familyName": "Vanderleest",
"givenName": "Timothy E.",
"id": "sg:person.01257445163.89",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257445163.89"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Biological Sciences, University of Denver, 80208, Denver, CO, USA",
"id": "http://www.grid.ac/institutes/grid.266239.a",
"name": [
"Department of Biological Sciences, University of Denver, 80208, Denver, CO, USA"
],
"type": "Organization"
},
"familyName": "Miao",
"givenName": "Hui",
"id": "sg:person.01341221323.52",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341221323.52"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Biological Sciences, University of Denver, 80208, Denver, CO, USA",
"id": "http://www.grid.ac/institutes/grid.266239.a",
"name": [
"Department of Biological Sciences, University of Denver, 80208, Denver, CO, USA"
],
"type": "Organization"
},
"familyName": "Xie",
"givenName": "Yi",
"id": "sg:person.01321756676.01",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01321756676.01"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Physics, University of Denver, 80208, Denver, CO, USA",
"id": "http://www.grid.ac/institutes/grid.266239.a",
"name": [
"Department of Physics, University of Denver, 80208, Denver, CO, USA"
],
"type": "Organization"
},
"familyName": "Madhu",
"givenName": "Roopa",
"id": "sg:person.010254042777.61",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010254042777.61"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Physics, University of Denver, 80208, Denver, CO, USA",
"id": "http://www.grid.ac/institutes/grid.266239.a",
"name": [
"Department of Physics, University of Denver, 80208, Denver, CO, USA"
],
"type": "Organization"
},
"familyName": "Loerke",
"givenName": "Dinah",
"id": "sg:person.01255445236.88",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255445236.88"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Biological Sciences, University of Denver, 80208, Denver, CO, USA",
"id": "http://www.grid.ac/institutes/grid.266239.a",
"name": [
"Department of Biological Sciences, University of Denver, 80208, Denver, CO, USA"
],
"type": "Organization"
},
"familyName": "Blankenship",
"givenName": "J. Todd",
"id": "sg:person.01240645011.37",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01240645011.37"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1038/ncb2224",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002431551",
"https://doi.org/10.1038/ncb2224"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ng1622",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022081541",
"https://doi.org/10.1038/ng1622"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ncomms14528",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1083860049",
"https://doi.org/10.1038/ncomms14528"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nmeth.1237",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014167362",
"https://doi.org/10.1038/nmeth.1237"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature02590",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026028927",
"https://doi.org/10.1038/nature02590"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ncb2454",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025763456",
"https://doi.org/10.1038/ncb2454"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ncb2796",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033494938",
"https://doi.org/10.1038/ncb2796"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ng.2452",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009091081",
"https://doi.org/10.1038/ng.2452"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ncb2279",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046208104",
"https://doi.org/10.1038/ncb2279"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature14603",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041672041",
"https://doi.org/10.1038/nature14603"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature07522",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008738516",
"https://doi.org/10.1038/nature07522"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ncb1798",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019439618",
"https://doi.org/10.1038/ncb1798"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature09566",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016876949",
"https://doi.org/10.1038/nature09566"
],
"type": "CreativeWork"
}
],
"datePublished": "2017-09-07",
"datePublishedReg": "2017-09-07",
"description": "The coordination between membrane trafficking and actomyosin networks is essential to the regulation of cell and tissue shape. Here, we examine Rab protein distributions during Drosophila epithelial tissue remodeling and show that Rab35 is dynamically planar polarized. Rab35 compartments are enriched at contractile interfaces of intercalating cells and provide the first evidence of interfacial monopolarity. When Rab35 function is disrupted, apical area oscillations still occur and contractile steps are observed. However, contractions are followed by reversals and interfaces fail to shorten, demonstrating that Rab35 functions as a ratchet ensuring unidirectional movement. Although actomyosin forces have been thought to drive interface contraction, initiation of Rab35 compartments does not require Myosin II function. However, Rab35 compartments do not terminate and continue to grow into large elongated structures following actomyosin disruption. Finally, Rab35 represents a common contractile cell-shaping mechanism, as mesoderm invagination fails in Rab35 compromised embryos and Rab35 localizes to constricting surfaces.",
"genre": "article",
"id": "sg:pub.10.1038/s41467-017-00553-0",
"inLanguage": "en",
"isAccessibleForFree": true,
"isFundedItemOf": [
{
"id": "sg:grant.4729683",
"type": "MonetaryGrant"
},
{
"id": "sg:grant.2520679",
"type": "MonetaryGrant"
},
{
"id": "sg:grant.7026356",
"type": "MonetaryGrant"
}
],
"isPartOf": [
{
"id": "sg:journal.1043282",
"issn": [
"2041-1723"
],
"name": "Nature Communications",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "8"
}
],
"keywords": [
"Rab35 function",
"Drosophila epithelial tissues",
"myosin II function",
"regulation of cell",
"mesoderm invagination",
"Drosophila epithelia",
"cell intercalation",
"membrane trafficking",
"actomyosin network",
"actomyosin forces",
"Rab35",
"protein distribution",
"tissue shape",
"epithelial tissues",
"unidirectional movement",
"first evidence",
"compartments",
"cells",
"trafficking",
"embryos",
"interface contraction",
"invagination",
"ratchet",
"regulation",
"function",
"disruption",
"monopolarity",
"tissue",
"epithelium",
"mechanism",
"initiation",
"evidence",
"structure",
"step",
"distribution",
"contraction",
"movement",
"reversal",
"coordination",
"shape",
"network",
"interface",
"surface",
"intercalation",
"force",
"oscillations",
"area oscillations",
"planar"
],
"name": "Planar polarized Rab35 functions as an oscillatory ratchet during cell intercalation in the Drosophila epithelium",
"pagination": "476",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1091465435"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/s41467-017-00553-0"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"28883443"
]
}
],
"sameAs": [
"https://doi.org/10.1038/s41467-017-00553-0",
"https://app.dimensions.ai/details/publication/pub.1091465435"
],
"sdDataset": "articles",
"sdDatePublished": "2022-05-20T07:33",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/article/article_730.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1038/s41467-017-00553-0"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41467-017-00553-0'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41467-017-00553-0'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41467-017-00553-0'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41467-017-00553-0'
This table displays all metadata directly associated to this object as RDF triples.
267 TRIPLES
22 PREDICATES
101 URIs
80 LITERALS
21 BLANK NODES