Patient eligibility for hematopoietic stem cell transplantation: a review of patient-associated variables View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-03

AUTHORS

J. Tay, A. Daly, K. Jamani, L. Labelle, L. Savoie, D. Stewart, J. Storek, S. Beattie

ABSTRACT

Assessing patient eligibility for hematopoietic stem cell transplantation (HSCT) remains a complex, multifaceted challenge. Among these challenges, the paucity of comprehensive clinical data to guide decision making remains problematic coupled with unclear trade-offs between patient, disease and local HSCT center factors. Moreover, it is unclear that the modification of poor patient characteristics will improve post-HSCT outcomes. However, the use of Comorbidity Indices and Comprehensive Geriatric Assessments helps meet this challenge, but may be limited by overlapping patient characteristics. The increasing consideration for pre-HSCT psychosocial assessments and interventions remains to be studied. Ultimately, the decision to proceed with a HSCT remains interdisciplinary while considering the available evidence discussed in this review. More... »

PAGES

368-382

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    http://scigraph.springernature.com/pub.10.1038/s41409-018-0265-7

    DOI

    http://dx.doi.org/10.1038/s41409-018-0265-7

    DIMENSIONS

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/29988063


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