Ontology type: schema:ScholarlyArticle Open Access: True
2019-12
AUTHORSNicola Wright, Jonathan Hill, Andrew Pickles, Helen Sharp
ABSTRACTCallous-unemotional (CU) traits are thought to confer risk for aggression via reduced amygdala responsivity to distress cues in others. Low cortisol reactivity is thought to confer risk for aggression via reduced arousal and this effect may be confined to boys. We tested the hypothesis that the association between childhood CU traits and aggression would be greatest in the absence of the inhibitory effects of cortisol reactivity, and that this effect would be sex dependent. Participants were 283 members of a stratified subsample within an epidemiological longitudinal cohort (WCHADS). Cortisol reactivity to a social stressor was assessed at 5 years. CU traits were reported by mothers at 5 years, and physical aggression by mothers and teachers at age 7. Results showed that CU traits were associated with elevated aggression at 7 years controlling for earlier aggression. There was no main effect of cortisol reactivity on regression. The association between CU traits and aggression was moderated by cortisol reactivity (p = .011) with a strong association between CU traits and aggression in the presence of low reactivity, and a small and non-significant association in the presence of high reactivity. This association was further moderated by child sex (p = .041) with the joint effect of high CU traits and low cortisol reactivity seen only in boys (p = .016). We report first evidence that a combined deficit in inhibitory processes associated with CU traits and low cortisol reactivity increases risk for childhood aggression, in a sex-dependent manner. More... »
PAGES79
http://scigraph.springernature.com/pub.10.1038/s41398-019-0406-9
DOIhttp://dx.doi.org/10.1038/s41398-019-0406-9
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1112058002
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/30741941
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1701",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Psychology",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/17",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Psychology and Cognitive Sciences",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "King's College London",
"id": "https://www.grid.ac/institutes/grid.13097.3c",
"name": [
"Biostatistics Department at the Institute of Psychiatry, King\u2019s College London, London, UK"
],
"type": "Organization"
},
"familyName": "Wright",
"givenName": "Nicola",
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Reading",
"id": "https://www.grid.ac/institutes/grid.9435.b",
"name": [
"School of Psychology and Clinical Language Sciences, University of Reading, Reading, UK"
],
"type": "Organization"
},
"familyName": "Hill",
"givenName": "Jonathan",
"type": "Person"
},
{
"affiliation": {
"alternateName": "King's College London",
"id": "https://www.grid.ac/institutes/grid.13097.3c",
"name": [
"Biostatistics Department at the Institute of Psychiatry, King\u2019s College London, London, UK"
],
"type": "Organization"
},
"familyName": "Pickles",
"givenName": "Andrew",
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Liverpool",
"id": "https://www.grid.ac/institutes/grid.10025.36",
"name": [
"Department of Psychological Science, Institute of Psychology, Health and Society, University of Liverpool, Liverpool, UK"
],
"type": "Organization"
},
"familyName": "Sharp",
"givenName": "Helen",
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1111/jcpp.12326",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000467759"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.psyneuen.2008.09.006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001476038"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.psyneuen.2008.09.006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001476038"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/jnnp.71.6.727",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002247018"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jaac.2010.03.014",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003145998"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0191-8869(98)00231-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004506529"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1037/0022-3514.95.1.197",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006974462"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1469-7610.1997.tb01545.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007188964"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1037/0033-2909.133.1.149",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007225218"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/1073191114556101",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009061802"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/1073191114556101",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009061802"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/dev.20300",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010157285"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1207/s15374424jccp3301_6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010765904"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1037/a0033076",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011404922"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1017/s0954579412001150",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016548354"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/yco.0b013e32832bfa6d",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016616713"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/yco.0b013e32832bfa6d",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016616713"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/yco.0b013e32832bfa6d",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016616713"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/archgenpsychiatry.2007.27",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017622279"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1469-7610.2010.02323.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018667666"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1037/0021-843x.109.2.335",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020629136"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1037/0021-843x.109.2.335",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020629136"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1037/a0022303",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021477158"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1467-8624.2005.00890.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021685329"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1467-8624.2005.00890.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021685329"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1037/0022-006x.73.3.400",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022913415"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1037/0022-006x.73.3.400",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022913415"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10802-007-9204-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025017067",
"https://doi.org/10.1007/s10802-007-9204-6"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10862-010-9195-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025873096",
"https://doi.org/10.1007/s10862-010-9195-4"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1098/rstb.2008.0029",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026679947"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/1467-8624.00369",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027773740"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00127-011-0374-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030570605",
"https://doi.org/10.1007/s00127-011-0374-8"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1017/s0954579412001101",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032753465"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.psyneuen.2012.11.013",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033143197"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.psyneuen.2008.03.005",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033285030"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.tics.2007.07.003",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033464465"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10826-013-9756-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038471912",
"https://doi.org/10.1007/s10826-013-9756-8"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1037/0012-1649.43.1.13",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039622118"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1523/jneurosci.0499-06.2006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041214355"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/dev.21267",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042351116"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrn3577",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045203387",
"https://doi.org/10.1038/nrn3577"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/978-1-4757-4648-8_1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046528344",
"https://doi.org/10.1007/978-1-4757-4648-8_1"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00702-010-0386-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048183123",
"https://doi.org/10.1007/s00702-010-0386-7"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00702-010-0386-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048183123",
"https://doi.org/10.1007/s00702-010-0386-7"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.psyneuen.2009.02.010",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048858615"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.psyneuen.2016.05.021",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049895288"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1469-8986.1994.tb02440.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051440355"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1371/journal.pone.0045446",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051680788"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1037/1040-3590.9.1.47",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051779887"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.neubiorev.2017.03.016",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1084098150"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1017/s0954579417000293",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1084119347"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/jcpp.12750",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1085748771"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/jcpp.12784",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1090738450"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/jcpp.12784",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1090738450"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/jcpp.12784",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1090738450"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/jcpp.12867",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1100692860"
],
"type": "CreativeWork"
}
],
"datePublished": "2019-12",
"datePublishedReg": "2019-12-01",
"description": "Callous-unemotional (CU) traits are thought to confer risk for aggression via reduced amygdala responsivity to distress cues in others. Low cortisol reactivity is thought to confer risk for aggression via reduced arousal and this effect may be confined to boys. We tested the hypothesis that the association between childhood CU traits and aggression would be greatest in the absence of the inhibitory effects of cortisol reactivity, and that this effect would be sex dependent. Participants were 283 members of a stratified subsample within an epidemiological longitudinal cohort (WCHADS). Cortisol reactivity to a social stressor was assessed at 5 years. CU traits were reported by mothers at 5 years, and physical aggression by mothers and teachers at age 7. Results showed that CU traits were associated with elevated aggression at 7 years controlling for earlier aggression. There was no main effect of cortisol reactivity on regression. The association between CU traits and aggression was moderated by cortisol reactivity (p\u2009=\u2009.011) with a strong association between CU traits and aggression in the presence of low reactivity, and a small and non-significant association in the presence of high reactivity. This association was further moderated by child sex (p\u2009=\u2009.041) with the joint effect of high CU traits and low cortisol reactivity seen only in boys (p\u2009=\u2009.016). We report first evidence that a combined deficit in inhibitory processes associated with CU traits and low cortisol reactivity increases risk for childhood aggression, in a sex-dependent manner.",
"genre": "research_article",
"id": "sg:pub.10.1038/s41398-019-0406-9",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isFundedItemOf": [
{
"id": "sg:grant.2770627",
"type": "MonetaryGrant"
},
{
"id": "sg:grant.2770300",
"type": "MonetaryGrant"
},
{
"id": "sg:grant.3956573",
"type": "MonetaryGrant"
}
],
"isPartOf": [
{
"id": "sg:journal.1045271",
"issn": [
"2158-3188"
],
"name": "Translational Psychiatry",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "9"
}
],
"name": "Callous-unemotional traits, low cortisol reactivity and physical aggression in children: findings from the Wirral Child Health and Development Study",
"pagination": "79",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"53992184cc1a031da2dd5ddb2ecf90e1ad65d05376333a871ad07e452634e949"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"30741941"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"101562664"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/s41398-019-0406-9"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1112058002"
]
}
],
"sameAs": [
"https://doi.org/10.1038/s41398-019-0406-9",
"https://app.dimensions.ai/details/publication/pub.1112058002"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T13:18",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000368_0000000368/records_78938_00000001.jsonl",
"type": "ScholarlyArticle",
"url": "https://www.nature.com/articles/s41398-019-0406-9"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41398-019-0406-9'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41398-019-0406-9'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41398-019-0406-9'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41398-019-0406-9'
This table displays all metadata directly associated to this object as RDF triples.
242 TRIPLES
21 PREDICATES
75 URIs
21 LITERALS
9 BLANK NODES