European experience and risk factor analysis of donor cell-derived leukaemias/MDS following haematopoietic cell transplantation View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-07-26

AUTHORS

Nicole Engel, Alicia Rovo, Manuela Badoglio, Myriam Labopin, Grzegorz W. Basak, Yves Beguin, Denis Guyotat, Per Ljungman, Arnon Nagler, Anton Schattenberg, Thomas Schroeder, Wilfried Schroyens, Johanna Tischer, Gerard Socie, Hans-Jochem Kolb, Andre Tichelli, Nina Salooja, Rafael F. Duarte

ABSTRACT

Donor cell leukaemia (DCL) is a rare complication of allogeneic haematopoietic cell transplantation (HCT). We have investigated the prevalence and outcome of donor cell haematology malignancies within centres registered with the European Society of Blood and Marrow transplantation (EBMT). We have sought to identify risk factors to shed light on the pathogenesis of DCL as a model for leukaemogenesis. DCL cases were identified by questionnaire and a follow-up questionnaire requested detailed data. Control subjects from the EBMT registry who had not developed DCL were used for a matched pair analysis to identify risk factors. We identified 38 patients with DCL; the estimated prevalence was 80.5/100,000 transplants. Patients were predominantly treated for haematological malignancy. A clone was retrospectively identified in 7/25 (28%) donors for whom data was available. Overall survival was poor with 29/38 patients dead a median of 11 (range 0-91) months after DCL diagnosis. Matched case-pair analysis identified three factors on multivariate analysis as significantly associated with an increased risk for DCL: use of growth factors within the first 100 days after transplantation, in vivo T-cell depletion and multiple allografts. The risk factors identified, support reduced immune surveillance and replicative stress as pathogenic in the development of DCL. More... »

PAGES

1-10

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/s41375-018-0218-6

DOI

http://dx.doi.org/10.1038/s41375-018-0218-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1105854134

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30050122


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Ludwig Maximilian University of Munich", 
          "id": "https://www.grid.ac/institutes/grid.5252.0", 
          "name": [
            "Department of Internal Medicine III, Campus Gro\u00dfhadern, University of Munich, Munich, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Engel", 
        "givenName": "Nicole", 
        "id": "sg:person.01362332146.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362332146.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Children\u2019s Hospital Bern", 
          "id": "https://www.grid.ac/institutes/grid.412353.2", 
          "name": [
            "Department of Haematology, University hospital of Bern, Bern, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rovo", 
        "givenName": "Alicia", 
        "id": "sg:person.01210070346.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01210070346.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Saint-Antoine", 
          "id": "https://www.grid.ac/institutes/grid.412370.3", 
          "name": [
            "Department of Haematology, EBMT Paris study office, Saint Antoine Hospital, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Badoglio", 
        "givenName": "Manuela", 
        "id": "sg:person.0623632634.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623632634.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Saint-Antoine", 
          "id": "https://www.grid.ac/institutes/grid.412370.3", 
          "name": [
            "Department of Haematology, EBMT Paris study office, Saint Antoine Hospital, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Labopin", 
        "givenName": "Myriam", 
        "id": "sg:person.0762572112.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0762572112.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medical University of Warsaw", 
          "id": "https://www.grid.ac/institutes/grid.13339.3b", 
          "name": [
            "Department of Haematology, Oncology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Basak", 
        "givenName": "Grzegorz W.", 
        "id": "sg:person.0710473535.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710473535.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Li\u00e8ge", 
          "id": "https://www.grid.ac/institutes/grid.4861.b", 
          "name": [
            "Division of Haematology, Department of Medicine, University of Li\u00e8ge, Li\u00e8ge, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Beguin", 
        "givenName": "Yves", 
        "id": "sg:person.01351511132.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351511132.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "L\u2019Institut de Canc\u00e9rologie de la Loire, Saint-Priest-en-Jarez, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Guyotat", 
        "givenName": "Denis", 
        "id": "sg:person.0655776276.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0655776276.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Karolinska Institute", 
          "id": "https://www.grid.ac/institutes/grid.4714.6", 
          "name": [
            "Karolinska Institute, Haematology, Stockholm, Sweden"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ljungman", 
        "givenName": "Per", 
        "id": "sg:person.01077046511.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077046511.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Saint-Antoine", 
          "id": "https://www.grid.ac/institutes/grid.412370.3", 
          "name": [
            "The Chaim Sheba Medical Center, Bone Marrow Transplantation Department, Tel Hashomer, Israel", 
            "Chair of the ALWP EBMT Paris Office, Hospital Saint Antoine, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nagler", 
        "givenName": "Arnon", 
        "id": "sg:person.0644252102.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0644252102.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Radboud University Nijmegen Medical Centre", 
          "id": "https://www.grid.ac/institutes/grid.10417.33", 
          "name": [
            "Department of Haematology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schattenberg", 
        "givenName": "Anton", 
        "id": "sg:person.014214642074.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014214642074.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heinrich Heine University D\u00fcsseldorf", 
          "id": "https://www.grid.ac/institutes/grid.411327.2", 
          "name": [
            "Department of Haematology, Oncology und Clinical Immunology, University of Duesseldorf, Medical Faculty, Duesseldorf, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schroeder", 
        "givenName": "Thomas", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Haematology, University of Antwerp, Antwerpen, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schroyens", 
        "givenName": "Wilfried", 
        "id": "sg:person.0653223122.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0653223122.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ludwig Maximilian University of Munich", 
          "id": "https://www.grid.ac/institutes/grid.5252.0", 
          "name": [
            "Department of Internal Medicine III, Campus Gro\u00dfhadern, University of Munich, Munich, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tischer", 
        "givenName": "Johanna", 
        "id": "sg:person.0726516141.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0726516141.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Saint-Louis", 
          "id": "https://www.grid.ac/institutes/grid.413328.f", 
          "name": [
            "Department of Haematology, Immunology, Oncology, APHP Hospital Saint Louis, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Socie", 
        "givenName": "Gerard", 
        "id": "sg:person.015747476457.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015747476457.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ludwig Maximilian University of Munich", 
          "id": "https://www.grid.ac/institutes/grid.5252.0", 
          "name": [
            "Unit for Haematopoietic Cell Transplantation, Campus Gro\u00dfhadern, University of Munich, Munich, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kolb", 
        "givenName": "Hans-Jochem", 
        "id": "sg:person.01332010455.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01332010455.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospital of Basel", 
          "id": "https://www.grid.ac/institutes/grid.410567.1", 
          "name": [
            "Department of Haematology, University Hospital, Basel, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tichelli", 
        "givenName": "Andre", 
        "id": "sg:person.0674766513.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674766513.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Imperial College London", 
          "id": "https://www.grid.ac/institutes/grid.7445.2", 
          "name": [
            "Centre for Haematology, Imperial College London, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Salooja", 
        "givenName": "Nina", 
        "id": "sg:person.0575377452.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0575377452.83"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario Puerta de Hierro Majadahonda", 
          "id": "https://www.grid.ac/institutes/grid.73221.35", 
          "name": [
            "Department of Haematology, Hospital Universitario Puerta de Hierro, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Duarte", 
        "givenName": "Rafael F.", 
        "id": "sg:person.01321024667.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01321024667.53"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1002/ajh.10286", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000255270"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1309/ajcppjuq9dnr1ghp", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001003352"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/pbc.22617", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001518074"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/pbc.22617", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001518074"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2010-08-300673", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002681978"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature08851", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003023917", 
          "https://doi.org/10.1038/nature08851"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature08851", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003023917", 
          "https://doi.org/10.1038/nature08851"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1590/s1415-47572012005000056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003504983"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbmt.2005.09.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008226664"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm198909213211203", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008484259"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbmt.2006.01.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015659232"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-0609.2011.01741.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017123423"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bmt.2008.443", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018879724", 
          "https://doi.org/10.1038/bmt.2008.443"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ajh.20111", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019851984"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/10428190600693099", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021254929"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2015-03-631747", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021457668"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1704588", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021540960", 
          "https://doi.org/10.1038/sj.bmt.1704588"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbmt.2010.10.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023823975"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1399-3046.2011.01584.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027810434"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1705750", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031438922", 
          "https://doi.org/10.1038/sj.bmt.1705750"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(71)90998-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033290104"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(71)90998-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033290104"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bmt.2014.294", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033494998", 
          "https://doi.org/10.1038/bmt.2014.294"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/leu.2016.310", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034798043", 
          "https://doi.org/10.1038/leu.2016.310"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1703360", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036698319", 
          "https://doi.org/10.1038/sj.bmt.1703360"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/bjh.13504", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043649754"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-0609.2006.00716.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044269332"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gcc.20286", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046663433"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gcc.20286", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046663433"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1537-2995.2008.02008.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051377884"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077075532", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079173143", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2017/3728429", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083915419"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2017/3728429", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083915419"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/leu.2017.104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084128335", 
          "https://doi.org/10.1038/leu.2017.104"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/pbc.26823", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091831092"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2169/internalmedicine.9005-17", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1092787448"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-07-26", 
    "datePublishedReg": "2018-07-26", 
    "description": "Donor cell leukaemia (DCL) is a rare complication of allogeneic haematopoietic cell transplantation (HCT). We have investigated the prevalence and outcome of donor cell haematology malignancies within centres registered with the European Society of Blood and Marrow transplantation (EBMT). We have sought to identify risk factors to shed light on the pathogenesis of DCL as a model for leukaemogenesis. DCL cases were identified by questionnaire and a follow-up questionnaire requested detailed data. Control subjects from the EBMT registry who had not developed DCL were used for a matched pair analysis to identify risk factors. We identified 38 patients with DCL; the estimated prevalence was 80.5/100,000 transplants. Patients were predominantly treated for haematological malignancy. A clone was retrospectively identified in 7/25 (28%) donors for whom data was available. Overall survival was poor with 29/38 patients dead a median of 11 (range 0-91) months after DCL diagnosis. Matched case-pair analysis identified three factors on multivariate analysis as significantly associated with an increased risk for DCL: use of growth factors within the first 100 days after transplantation, in vivo T-cell depletion and multiple allografts. The risk factors identified, support reduced immune surveillance and replicative stress as pathogenic in the development of DCL.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/s41375-018-0218-6", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1097065", 
        "issn": [
          "0887-6924", 
          "1476-5551"
        ], 
        "name": "Leukemia", 
        "type": "Periodical"
      }
    ], 
    "name": "European experience and risk factor analysis of donor cell-derived leukaemias/MDS following haematopoietic cell transplantation", 
    "pagination": "1-10", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "cc2c0b2a12254314a34254a038ba25e9b9997c553b6a30330f5044c6920e653a"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30050122"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8704895"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/s41375-018-0218-6"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1105854134"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/s41375-018-0218-6", 
      "https://app.dimensions.ai/details/publication/pub.1105854134"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T13:27", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8659_00000566.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/s41375-018-0218-6"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/s41375-018-0218-6'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/s41375-018-0218-6'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/s41375-018-0218-6'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/s41375-018-0218-6'


 

This table displays all metadata directly associated to this object as RDF triples.

323 TRIPLES      21 PREDICATES      58 URIs      18 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/s41375-018-0218-6 schema:about anzsrc-for:11
2 anzsrc-for:1102
3 schema:author N4e5a1eb5323945f8ac075c7fc372ba92
4 schema:citation sg:pub.10.1038/bmt.2008.443
5 sg:pub.10.1038/bmt.2014.294
6 sg:pub.10.1038/leu.2016.310
7 sg:pub.10.1038/leu.2017.104
8 sg:pub.10.1038/nature08851
9 sg:pub.10.1038/sj.bmt.1703360
10 sg:pub.10.1038/sj.bmt.1704588
11 sg:pub.10.1038/sj.bmt.1705750
12 https://app.dimensions.ai/details/publication/pub.1077075532
13 https://app.dimensions.ai/details/publication/pub.1079173143
14 https://doi.org/10.1002/ajh.10286
15 https://doi.org/10.1002/ajh.20111
16 https://doi.org/10.1002/gcc.20286
17 https://doi.org/10.1002/pbc.22617
18 https://doi.org/10.1002/pbc.26823
19 https://doi.org/10.1016/j.bbmt.2005.09.004
20 https://doi.org/10.1016/j.bbmt.2006.01.006
21 https://doi.org/10.1016/j.bbmt.2010.10.010
22 https://doi.org/10.1016/s0140-6736(71)90998-6
23 https://doi.org/10.1056/nejm198909213211203
24 https://doi.org/10.1080/10428190600693099
25 https://doi.org/10.1111/bjh.13504
26 https://doi.org/10.1111/j.1399-3046.2011.01584.x
27 https://doi.org/10.1111/j.1537-2995.2008.02008.x
28 https://doi.org/10.1111/j.1600-0609.2006.00716.x
29 https://doi.org/10.1111/j.1600-0609.2011.01741.x
30 https://doi.org/10.1155/2017/3728429
31 https://doi.org/10.1182/blood-2010-08-300673
32 https://doi.org/10.1182/blood-2015-03-631747
33 https://doi.org/10.1309/ajcppjuq9dnr1ghp
34 https://doi.org/10.1590/s1415-47572012005000056
35 https://doi.org/10.2169/internalmedicine.9005-17
36 schema:datePublished 2018-07-26
37 schema:datePublishedReg 2018-07-26
38 schema:description Donor cell leukaemia (DCL) is a rare complication of allogeneic haematopoietic cell transplantation (HCT). We have investigated the prevalence and outcome of donor cell haematology malignancies within centres registered with the European Society of Blood and Marrow transplantation (EBMT). We have sought to identify risk factors to shed light on the pathogenesis of DCL as a model for leukaemogenesis. DCL cases were identified by questionnaire and a follow-up questionnaire requested detailed data. Control subjects from the EBMT registry who had not developed DCL were used for a matched pair analysis to identify risk factors. We identified 38 patients with DCL; the estimated prevalence was 80.5/100,000 transplants. Patients were predominantly treated for haematological malignancy. A clone was retrospectively identified in 7/25 (28%) donors for whom data was available. Overall survival was poor with 29/38 patients dead a median of 11 (range 0-91) months after DCL diagnosis. Matched case-pair analysis identified three factors on multivariate analysis as significantly associated with an increased risk for DCL: use of growth factors within the first 100 days after transplantation, in vivo T-cell depletion and multiple allografts. The risk factors identified, support reduced immune surveillance and replicative stress as pathogenic in the development of DCL.
39 schema:genre research_article
40 schema:inLanguage en
41 schema:isAccessibleForFree false
42 schema:isPartOf sg:journal.1097065
43 schema:name European experience and risk factor analysis of donor cell-derived leukaemias/MDS following haematopoietic cell transplantation
44 schema:pagination 1-10
45 schema:productId N213fe03919414c5ba02ccf3d6989d1e2
46 N24baf0daff0042aca35f6e6136958a62
47 N5ea95f1b895b47e1a25c83ef9368668b
48 N614f5049ef3540bebe926f7a6e537ea7
49 Nb6b6f96657a947658445ee0b360bd3b7
50 schema:sameAs https://app.dimensions.ai/details/publication/pub.1105854134
51 https://doi.org/10.1038/s41375-018-0218-6
52 schema:sdDatePublished 2019-04-10T13:27
53 schema:sdLicense https://scigraph.springernature.com/explorer/license/
54 schema:sdPublisher Ne22de287dce048f992803dcbf780a9ce
55 schema:url https://www.nature.com/articles/s41375-018-0218-6
56 sgo:license sg:explorer/license/
57 sgo:sdDataset articles
58 rdf:type schema:ScholarlyArticle
59 N0e5dffddf01342f9b30538d880699a47 rdf:first sg:person.01077046511.37
60 rdf:rest N45a5cf73727a49219d8f9e1917929d1e
61 N213fe03919414c5ba02ccf3d6989d1e2 schema:name dimensions_id
62 schema:value pub.1105854134
63 rdf:type schema:PropertyValue
64 N24baf0daff0042aca35f6e6136958a62 schema:name doi
65 schema:value 10.1038/s41375-018-0218-6
66 rdf:type schema:PropertyValue
67 N2736e485a29f4f218c1ade3fbd1c2d38 rdf:first sg:person.0653223122.50
68 rdf:rest N68ce8cf09dde4cc1a52699963c7d3f9d
69 N2f75d10534444bc990e31ec652657423 schema:affiliation https://www.grid.ac/institutes/grid.411327.2
70 schema:familyName Schroeder
71 schema:givenName Thomas
72 rdf:type schema:Person
73 N3603486fe3b04db38984bb591f934829 rdf:first sg:person.0623632634.46
74 rdf:rest N9fb1cac4eceb4563b53773216a160215
75 N39de147081b2449196b63ebb028c677e rdf:first sg:person.0710473535.27
76 rdf:rest N3d2bafe972b74ba1ae5863b5de1245db
77 N3d2bafe972b74ba1ae5863b5de1245db rdf:first sg:person.01351511132.15
78 rdf:rest Ne6fe5d46cf8a47a685c5dd2389e09f7f
79 N3fbffc8028304dd19900d049284be575 schema:name L’Institut de Cancérologie de la Loire, Saint-Priest-en-Jarez, France
80 rdf:type schema:Organization
81 N45a5cf73727a49219d8f9e1917929d1e rdf:first sg:person.0644252102.00
82 rdf:rest N88a2a7e87b8d424fb6c9af4ce3580fe1
83 N4e5a1eb5323945f8ac075c7fc372ba92 rdf:first sg:person.01362332146.99
84 rdf:rest N84e32ba4955e4aa287507efec8814788
85 N5ea95f1b895b47e1a25c83ef9368668b schema:name readcube_id
86 schema:value cc2c0b2a12254314a34254a038ba25e9b9997c553b6a30330f5044c6920e653a
87 rdf:type schema:PropertyValue
88 N614f5049ef3540bebe926f7a6e537ea7 schema:name pubmed_id
89 schema:value 30050122
90 rdf:type schema:PropertyValue
91 N68ce8cf09dde4cc1a52699963c7d3f9d rdf:first sg:person.0726516141.72
92 rdf:rest Ncdfc7d7c43c640e9a608c447785ae2bf
93 N6cccc46cdd3c47989b6cc7a5d664cde8 schema:name Department of Haematology, University of Antwerp, Antwerpen, The Netherlands
94 rdf:type schema:Organization
95 N84e32ba4955e4aa287507efec8814788 rdf:first sg:person.01210070346.32
96 rdf:rest N3603486fe3b04db38984bb591f934829
97 N88a2a7e87b8d424fb6c9af4ce3580fe1 rdf:first sg:person.014214642074.18
98 rdf:rest Nf80f317e26a64deeb87533f24c50c050
99 N9fb1cac4eceb4563b53773216a160215 rdf:first sg:person.0762572112.39
100 rdf:rest N39de147081b2449196b63ebb028c677e
101 Nb6b6f96657a947658445ee0b360bd3b7 schema:name nlm_unique_id
102 schema:value 8704895
103 rdf:type schema:PropertyValue
104 Nc2d522aec68e4c71917b66a8daec4c4b rdf:first sg:person.0575377452.83
105 rdf:rest Ne55b1ee732214466ab6911366ef4ca3c
106 Ncdfc7d7c43c640e9a608c447785ae2bf rdf:first sg:person.015747476457.00
107 rdf:rest Nd4e08d95114b46c3967cd9af1af359fb
108 Nd4e08d95114b46c3967cd9af1af359fb rdf:first sg:person.01332010455.05
109 rdf:rest Nf66daecaff3447dfa9974d56170000a7
110 Ne22de287dce048f992803dcbf780a9ce schema:name Springer Nature - SN SciGraph project
111 rdf:type schema:Organization
112 Ne55b1ee732214466ab6911366ef4ca3c rdf:first sg:person.01321024667.53
113 rdf:rest rdf:nil
114 Ne6fe5d46cf8a47a685c5dd2389e09f7f rdf:first sg:person.0655776276.35
115 rdf:rest N0e5dffddf01342f9b30538d880699a47
116 Nf66daecaff3447dfa9974d56170000a7 rdf:first sg:person.0674766513.32
117 rdf:rest Nc2d522aec68e4c71917b66a8daec4c4b
118 Nf80f317e26a64deeb87533f24c50c050 rdf:first N2f75d10534444bc990e31ec652657423
119 rdf:rest N2736e485a29f4f218c1ade3fbd1c2d38
120 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
121 schema:name Medical and Health Sciences
122 rdf:type schema:DefinedTerm
123 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
124 schema:name Cardiorespiratory Medicine and Haematology
125 rdf:type schema:DefinedTerm
126 sg:journal.1097065 schema:issn 0887-6924
127 1476-5551
128 schema:name Leukemia
129 rdf:type schema:Periodical
130 sg:person.01077046511.37 schema:affiliation https://www.grid.ac/institutes/grid.4714.6
131 schema:familyName Ljungman
132 schema:givenName Per
133 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077046511.37
134 rdf:type schema:Person
135 sg:person.01210070346.32 schema:affiliation https://www.grid.ac/institutes/grid.412353.2
136 schema:familyName Rovo
137 schema:givenName Alicia
138 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01210070346.32
139 rdf:type schema:Person
140 sg:person.01321024667.53 schema:affiliation https://www.grid.ac/institutes/grid.73221.35
141 schema:familyName Duarte
142 schema:givenName Rafael F.
143 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01321024667.53
144 rdf:type schema:Person
145 sg:person.01332010455.05 schema:affiliation https://www.grid.ac/institutes/grid.5252.0
146 schema:familyName Kolb
147 schema:givenName Hans-Jochem
148 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01332010455.05
149 rdf:type schema:Person
150 sg:person.01351511132.15 schema:affiliation https://www.grid.ac/institutes/grid.4861.b
151 schema:familyName Beguin
152 schema:givenName Yves
153 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351511132.15
154 rdf:type schema:Person
155 sg:person.01362332146.99 schema:affiliation https://www.grid.ac/institutes/grid.5252.0
156 schema:familyName Engel
157 schema:givenName Nicole
158 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362332146.99
159 rdf:type schema:Person
160 sg:person.014214642074.18 schema:affiliation https://www.grid.ac/institutes/grid.10417.33
161 schema:familyName Schattenberg
162 schema:givenName Anton
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014214642074.18
164 rdf:type schema:Person
165 sg:person.015747476457.00 schema:affiliation https://www.grid.ac/institutes/grid.413328.f
166 schema:familyName Socie
167 schema:givenName Gerard
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015747476457.00
169 rdf:type schema:Person
170 sg:person.0575377452.83 schema:affiliation https://www.grid.ac/institutes/grid.7445.2
171 schema:familyName Salooja
172 schema:givenName Nina
173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0575377452.83
174 rdf:type schema:Person
175 sg:person.0623632634.46 schema:affiliation https://www.grid.ac/institutes/grid.412370.3
176 schema:familyName Badoglio
177 schema:givenName Manuela
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623632634.46
179 rdf:type schema:Person
180 sg:person.0644252102.00 schema:affiliation https://www.grid.ac/institutes/grid.412370.3
181 schema:familyName Nagler
182 schema:givenName Arnon
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0644252102.00
184 rdf:type schema:Person
185 sg:person.0653223122.50 schema:affiliation N6cccc46cdd3c47989b6cc7a5d664cde8
186 schema:familyName Schroyens
187 schema:givenName Wilfried
188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0653223122.50
189 rdf:type schema:Person
190 sg:person.0655776276.35 schema:affiliation N3fbffc8028304dd19900d049284be575
191 schema:familyName Guyotat
192 schema:givenName Denis
193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0655776276.35
194 rdf:type schema:Person
195 sg:person.0674766513.32 schema:affiliation https://www.grid.ac/institutes/grid.410567.1
196 schema:familyName Tichelli
197 schema:givenName Andre
198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674766513.32
199 rdf:type schema:Person
200 sg:person.0710473535.27 schema:affiliation https://www.grid.ac/institutes/grid.13339.3b
201 schema:familyName Basak
202 schema:givenName Grzegorz W.
203 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0710473535.27
204 rdf:type schema:Person
205 sg:person.0726516141.72 schema:affiliation https://www.grid.ac/institutes/grid.5252.0
206 schema:familyName Tischer
207 schema:givenName Johanna
208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0726516141.72
209 rdf:type schema:Person
210 sg:person.0762572112.39 schema:affiliation https://www.grid.ac/institutes/grid.412370.3
211 schema:familyName Labopin
212 schema:givenName Myriam
213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0762572112.39
214 rdf:type schema:Person
215 sg:pub.10.1038/bmt.2008.443 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018879724
216 https://doi.org/10.1038/bmt.2008.443
217 rdf:type schema:CreativeWork
218 sg:pub.10.1038/bmt.2014.294 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033494998
219 https://doi.org/10.1038/bmt.2014.294
220 rdf:type schema:CreativeWork
221 sg:pub.10.1038/leu.2016.310 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034798043
222 https://doi.org/10.1038/leu.2016.310
223 rdf:type schema:CreativeWork
224 sg:pub.10.1038/leu.2017.104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084128335
225 https://doi.org/10.1038/leu.2017.104
226 rdf:type schema:CreativeWork
227 sg:pub.10.1038/nature08851 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003023917
228 https://doi.org/10.1038/nature08851
229 rdf:type schema:CreativeWork
230 sg:pub.10.1038/sj.bmt.1703360 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036698319
231 https://doi.org/10.1038/sj.bmt.1703360
232 rdf:type schema:CreativeWork
233 sg:pub.10.1038/sj.bmt.1704588 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021540960
234 https://doi.org/10.1038/sj.bmt.1704588
235 rdf:type schema:CreativeWork
236 sg:pub.10.1038/sj.bmt.1705750 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031438922
237 https://doi.org/10.1038/sj.bmt.1705750
238 rdf:type schema:CreativeWork
239 https://app.dimensions.ai/details/publication/pub.1077075532 schema:CreativeWork
240 https://app.dimensions.ai/details/publication/pub.1079173143 schema:CreativeWork
241 https://doi.org/10.1002/ajh.10286 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000255270
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1002/ajh.20111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019851984
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1002/gcc.20286 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046663433
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1002/pbc.22617 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001518074
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1002/pbc.26823 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091831092
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1016/j.bbmt.2005.09.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008226664
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1016/j.bbmt.2006.01.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015659232
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1016/j.bbmt.2010.10.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023823975
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1016/s0140-6736(71)90998-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033290104
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1056/nejm198909213211203 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008484259
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1080/10428190600693099 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021254929
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1111/bjh.13504 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043649754
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1111/j.1399-3046.2011.01584.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1027810434
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1111/j.1537-2995.2008.02008.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1051377884
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1111/j.1600-0609.2006.00716.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1044269332
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1111/j.1600-0609.2011.01741.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1017123423
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1155/2017/3728429 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083915419
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1182/blood-2010-08-300673 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002681978
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1182/blood-2015-03-631747 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021457668
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1309/ajcppjuq9dnr1ghp schema:sameAs https://app.dimensions.ai/details/publication/pub.1001003352
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1590/s1415-47572012005000056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003504983
282 rdf:type schema:CreativeWork
283 https://doi.org/10.2169/internalmedicine.9005-17 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092787448
284 rdf:type schema:CreativeWork
285 https://www.grid.ac/institutes/grid.10417.33 schema:alternateName Radboud University Nijmegen Medical Centre
286 schema:name Department of Haematology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
287 rdf:type schema:Organization
288 https://www.grid.ac/institutes/grid.13339.3b schema:alternateName Medical University of Warsaw
289 schema:name Department of Haematology, Oncology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland
290 rdf:type schema:Organization
291 https://www.grid.ac/institutes/grid.410567.1 schema:alternateName University Hospital of Basel
292 schema:name Department of Haematology, University Hospital, Basel, Switzerland
293 rdf:type schema:Organization
294 https://www.grid.ac/institutes/grid.411327.2 schema:alternateName Heinrich Heine University Düsseldorf
295 schema:name Department of Haematology, Oncology und Clinical Immunology, University of Duesseldorf, Medical Faculty, Duesseldorf, Germany
296 rdf:type schema:Organization
297 https://www.grid.ac/institutes/grid.412353.2 schema:alternateName University Children’s Hospital Bern
298 schema:name Department of Haematology, University hospital of Bern, Bern, Switzerland
299 rdf:type schema:Organization
300 https://www.grid.ac/institutes/grid.412370.3 schema:alternateName Hôpital Saint-Antoine
301 schema:name Chair of the ALWP EBMT Paris Office, Hospital Saint Antoine, Paris, France
302 Department of Haematology, EBMT Paris study office, Saint Antoine Hospital, Paris, France
303 The Chaim Sheba Medical Center, Bone Marrow Transplantation Department, Tel Hashomer, Israel
304 rdf:type schema:Organization
305 https://www.grid.ac/institutes/grid.413328.f schema:alternateName Hôpital Saint-Louis
306 schema:name Department of Haematology, Immunology, Oncology, APHP Hospital Saint Louis, Paris, France
307 rdf:type schema:Organization
308 https://www.grid.ac/institutes/grid.4714.6 schema:alternateName Karolinska Institute
309 schema:name Karolinska Institute, Haematology, Stockholm, Sweden
310 rdf:type schema:Organization
311 https://www.grid.ac/institutes/grid.4861.b schema:alternateName University of Liège
312 schema:name Division of Haematology, Department of Medicine, University of Liège, Liège, Belgium
313 rdf:type schema:Organization
314 https://www.grid.ac/institutes/grid.5252.0 schema:alternateName Ludwig Maximilian University of Munich
315 schema:name Department of Internal Medicine III, Campus Großhadern, University of Munich, Munich, Germany
316 Unit for Haematopoietic Cell Transplantation, Campus Großhadern, University of Munich, Munich, Germany
317 rdf:type schema:Organization
318 https://www.grid.ac/institutes/grid.73221.35 schema:alternateName Hospital Universitario Puerta de Hierro Majadahonda
319 schema:name Department of Haematology, Hospital Universitario Puerta de Hierro, Madrid, Spain
320 rdf:type schema:Organization
321 https://www.grid.ac/institutes/grid.7445.2 schema:alternateName Imperial College London
322 schema:name Centre for Haematology, Imperial College London, London, UK
323 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...